発表論文

TOP 発表論文 Papers 2026

研究成果

Papers 2026

  1. Wan, C., Wang, XQ., Yue, HR., Zhang, MM., Kondo, A., Haan, RD., Hasunuma, T., Li, K., Zhao, XQ. (2026/01) MDG1-mediated transcriptional reprogramming enhances cellulase production and alters thermal activity in recombinant Saccharomyces cerevisiae, Metabolic Engineering, 93,24-34

  2. Abe, M., Takeuchi, M., Kato, S.,* Hasunuma, T., Groger H., Hayashi T.* (2026/01) Organic solvent-tolerant bacteria as a host for whole-cell biocatalysis: Enzymatic dehydration of aldoximes in organic medium, Journal of Porphyrins and Phthalocyanines, 29, A-F

  3. Kato, S.,* Takeuchi, K., Umeda, K., Kudo, H., Hasunuma, T., Hayashi, T.* (2026/01) PCA-Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation, Angewandte Chemie International Edition, 65(10), e26025

  4. Takeuchi, K., Kato, S.,* Ueshima, R., Hayashi, T.* (2026/01) Directed Evolution Enhances the Peroxidation Activity of Myoglobin Reconstituted with an Iron Corrole Complex, Bulletin of the Chemical Society of Japan, 99(22), uoag024

  5. Li, X., Li, K., Zhang, F., Hasunuma, T., Kondo, A., Zhang, L., Zhao, X., Bai, F. (2026/03) CRISPR-based synthetic biology toolkit development in Candida viswanthii and functional analysis of the stress responsive Ena1-like protein, Synthetic and Systems Biotechnology, 11, 298-308

  6. Tomita, I., Bamba, T., Yoshida, T., Domingues, L., Nasuno, R., Hidese, R., Hasunuma, T. (2026/03) Biosynthetic platform for orsellinic acid-derived meroterpenoids in Escherichia coli, Metabolic Engineering, 94, 231-240

  7. Sekiya, R., Nakamoto, M.,* Kato, S., Hayashi, T., Matsusaki, M.* (2026/03) Injectable and transient hydrogel with programmable lifetime by endogenous coordination crosslinking and enzymatic de-crosslinking, Journal of Controlled Release, 394, 114867

  8. Kato, S.,* Hasunuma, T.* (2026/04) Expanding the Chemical Space of Biosynthesis through Chemistry-Inspired Enzymatic Transformations, Current Opinion in Biotechnology, in press

  9. Minnaar, L.S., Inokuma, K., Hasunuma, T., den Haan, R. (2026/05) Engineering natural Saccharomyces cerevisiae isolates for enhanced one-step cellulosic ethanol production, Applied Microbiology and Biotechnology, in press

  10. Nasuno, R., Kudo, H., Fushimi, K., Hidese, R., Kondo, A., Hasunuma, T. (2025/07) Amino acid deaminase outperforms transaminase in α-keto acid production from amino acids, Metabolic Engineering, 96, 234-242

  11. Matsuo, M., Hagino, K., Kawata, S., Hasunuma, T., Honda, K. Achieving Bottom-Up ELSI and RRI in Synthetic Biology Research Community from the Japanese Context, Frontiers in Genetics, in press

  12. Yoshida, T., Shintani, T., Sasaki, D., Vavricka, C., Matsuki, Y., Kondo, A., Hasunuma, T. Development of a quantitative serial LC–MS/MS method for gut microbiota metabolomics, ACS Omega, in press

  13. Kawahara, Y., Nasuno, R., Jin, Y.S., Hasunuma, T. Engineering a robust cell-surface display platform in the multi-stress-tolerant yeast Issatchenkia orientalis, Applied Microbiology and Biotechnology, in press

  14. Kawamoto, N., Kawagoe, Y., Yamada, Y., Hamaguchi, K., Shimakawa, G., Hasunuma, T., Tanaka, K., Nakanishi, S. Synchronous oscillation of photosynthetic electricity generation and carbon assimilation, Bioelectrochemistry, in press

総説・解説

  1. 加藤俊介，有機化学から代謝反応を考える，生物工学会誌 バイオミディア104(2): 68 (2026/02)

  2. 松尾真紀子(東京大学)，松本拓郎(文部科学省)，貴田うらら(経済産業省)，吉田彩乃(文部科学省)，横山修斗(内閣府)，味方和樹(NEDO)，水無渉(神戸大学)，蓮沼誠久(神戸大学)，城山英明(東京大学)，立川雅司(名古屋大学)，バイオものづくり政策の課題と提言－バイオエコノミー社会の実現に向けて， 東京大学未来ビジョン研究センター，政策提言No.40 (2026/05)

  3. 木村友紀，検出素子としての転写因子と遺伝子回路構築による応答調節，ぶんせき，5，155–156 (2026/05)

著書

  1. Tanaka, K., Vavricka, CJ., Hasunuma, T. Metabolomics: Big Data Approaches, Machine Learning and Big Data-enabled Biotechnology, Wiley-VCH, Chapter 10, 263-283 (2026/03)

  2. Nasuno, R., Xie, CY, Kawahara, Y., Tang, YQ., Hasunuma, T. Engineered Microbial Strains for Co-fermentation of C5 and C6 Sugars to Produce Cellulosic Ethanol, Advances in Biochemical Engineering/Biotechnology. Biotechnology for Utilization of Agricultural Residues, Springer, (2026/05)

  3. Wang, WB., Bamba, T., Cheng, C., Hasunuma, T., Kondo, A., Zhao, XQ., Bai, FW. Chapter 7. Metabolic engineering of microbial strains for 1,2,4-butanetriol production: progress and future perspectives, Advances in Biochemical Engineering/Biotechnology. Biotechnology for Utilization of Agricultural Residues, Springer, (2026/)

Chen J, Vavricka CJ, Wei S, Nakazawa Y, Matsumoto Y, Chen H, Tang Y, Liang J, Chen J, Huang Y, Noguchi K, Hasunuma T, Guan H, Li J, Liao C, Han Q