研究成果
Papers 2018
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Nambu-Nishida, Y., Sakihama, Y., Ishii, J., Hasunuma, T., Kondo, A. (2018/01) Selection of yeast Saccharomyces cerevisiae promoters available for xylose cultivation and fermentation, Journal of Bioscience and Bioengineering, 125(1), 76-86
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Matsumoto, T., Isogawa, Y., Tanaka, T., Kondo, A. (2018/01) Streptavidin-hydrogel prepared by sortase A-assisted click chemistry for enzyme immobilization on an electrode. Biosensors and Bioelectronics, 99, 56-61
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Sasaki, D., Sasaki, K., Ikuta, N., Yasuda, T., Fukuda, I., Kondo, A., Osawa, R. (2018/01) Low amounts of dietary fibre increase in vitro production of short-chain fatty acids without changing human colonic microbiota structure, Scientific Reports, 8, 435
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Oladejo, BO., Bi, Y., Vavricka, CJ., Li, C., Chai, Y., Xu, K., Li, L., Lu, Z., Li, J., Wong, G., Mohan, S., Pinto, BM., Jiang, H., Qi, J., Gao, GF., Tien, P., Wu, Y. (2018/01) Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus, BioRxiv, 378075
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Yamane-Koshizawa, D., Fujii, S., Maruno, T., Kobayashi, Y., Yamanaka, M., Wakai, S., Sambongi, Y. (2018/02) Stabilization of mesophilic Allochromatium vinosum cytochrome c' through specific mutations modeled by a thermophilic homologue, Bioscience, Biotechnology, and Biochemistry, 82, 304-311
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Li, YH., Zhang, XY., Zhang, F., Peng, LC., Zhang, DB., Kondo, A., Bai, FW., Zhao, X. (2018/02) Optimization of cellulolytic enzyme components through engineering Trichoderma reesei and on-site fermentation using the soluble inducer for cellulosic ethanol production from corn stover, Biotechnology for Biofuels, 11: 49
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Aikawa, S., Inokuma, K., Wakai, S., Sasaki, K., Ogino, C., Chang, JS, Hasunuma, T., Kondo, A. (2018/02) Direct and highly productive conversion of cyanobacteria Arthrospira platensis to ethanol with CaCl2 addition, Biotechnology for Biofuels, 11: 50
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Rahmani, N., Kahar, P., Lisdiyanti, P., Hermiati, Euis, Lee, J., Yopi, Y., Prasetya, B., Ogino, C., Kondo, A. (2018/02) Xylanase and feruloyl esterase from actinomycetes cultures could enhance sugarcane bagasse hydrolysis in the production of fermentable sugars, Bioscience, Biotechnology, and Biochemistry, 82(5), 904-915
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Nishimura, Y., Matsui, T., Ishii, J., Kondo, A. (2018/03) Metabolic Engineering of the 2-Ketobutyrate Biosynthetic Pathway for 1-Propanol Production in Saccharomyces cerevisiae, Microbial Cell Factories, 17: 38
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Bamba, T., Inokuma, K., Hasunuma, T., Kondo, A. (2018/03) Enhanced cell-surface display of a heterologous protein using SED1 anchoring system in SED1-disrupted Saccharomyces cerevisiae strain., Journal of Bioscience and Bioengineering, 125(3), 306-310
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Teramura, H., Sasaki, K., Oshima, T., Kawaguchi, H., Ogino, C., Sazuka, T., Kondo, A. (2018/03) Effective usage of sorghum bagasse: optimization of organosolv pretreatment using 25% 1-butanol and subsequent nanofiltration membrane separation, Bioresource Technology, 252, 157-164
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Gonçalves, G.A.L., Mori, Y., Tanaka, T., Kamiya, N. (2018/03) Casein-based scaffold for artificial cellulosome design., Process Biochemistry, 66, 140-145
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Fujii, S., Masanari-Fujii, M., Kobayashi, S., Kato, C., Nishiyama, M., Harada, Y., Wakai, S., Sambongi, Y. (2018/03) Commonly stabilized cytochromes c from deep-sea Shewanella and Pseudomonas, Bioscience, Biotechnology, and Biochemistry, 82, 792-799
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Takahashi, S., Kishi K., Hiraga R., Hayashi K., Mamada Y., Oshige, M., Katsura, S. (2018/03) A New Method for Immobilization of His-Tagged Proteins with the Application of Low-Frequency AC Electric Field. Sensors, 18, 784
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Hama, S., Noda, H., Kondo, A. (2018/04) How lipase technology contributes to evolution of biodiesel production using multiple feedstocks, Current Opinion in Biotechnology, 50, 57-64
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Sasaki, K., Sasaki, D., Kamiya, K., Nakanishi, S., Kondo, A., Kato, S. (2018/04) Electrochemical biotechnologies minimizing the required electrode assemblies, Current Opinion in Biotechnology, 50, 182-188
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Banno, S., Nishida, K., Arazoe, T., Mitsunobu, H., Kondo, A. (2018/04) Deaminase-mediated multiplex genome editing in Escherichia coli, Nature Microbiology, 3, 423-429
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Hashi, H., Nakamura, Y., Ishii, J., Kondo, A. (2018/04) Modifying expression modes of human neurotensin receptor type 1 alters sensing capabilities for agonists in yeast signaling biosensor, Biotechnology Journal, 13(4), e1700522
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Nambu-Nishida, Y., Nishida, K., Hasunuma, T., Kondo, A. (2018/04) Genetic and physiological basis for antibody production by Kluyveromyces marxianus, AMB Express, 8: 56
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Okano, K., Uematsu, G., Hama, S., Tanaka, T., Noda, H., Kondo, A., Honda, K. (2018/05) Metabolic engineering of Lactobacillus plantarum for direct L-lactic acid production from raw corn starch, Biotechnology Journal, 13(5), 1700517
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Thomson, NM., Shirai, T., Chiapello, M., Kondo, A., Mukherjee, KJ., Sivaniah, E., Numata, K., Summers, DK. (2018/05) Efficient 3-hydroxybutyrate production by quiescent Escherichia coli microbial cell factories is facilitated by indole-induced proteomic and metabolomic changes, Biotechnology Journal, 13(5), 1700571
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Tashiro, Y., Hirano, S., Matson, MM., Atsumi, S., Kondo, A. (2018/05) Electrical-biological hybrid system for CO2 reduction, Metabolic Engineering, 47, 211-218
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Kawaguchi, H., Yoshihara, K., Hara, K. Y., Hasunuma, T., Ogino, C., Kondo, A. (2018/05) Metabolome analysis-based design and engineering of a metabolic pathway in Corynebacterium glutamicum to match rates of simultaneous utilization of D-glucose and L-arabinose, Microbial Cell Factories, 17: 76
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Tominaga, D., Kawaguchi, H., Hori, Y., Hasunuma, T., Ogino, C., Aburatani, S. (2018/05) Mathematical model for small size time series data of bacterial secondary metabolic pathways, Bioinformatics and Biology Insights, 12: 1-7
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Sasaki, K., Sasaki, D., Tsuge, Y., Morita, M., Kondo, A. (2018/06) Changes in the microbial consortium during dark hydrogen fermentation in a bioelectrochemical system increases methane production during a two-stage process, Biotechnology for Biofuels, 11: 173
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Ishii, J., Morita, K., Ida, K., Kato, H., Kinoshita, S., Hataya, S., Shimizu, H., Kondo, A., Matsuda, F. (2018/06) A pyruvate carbon flux tugging strategy for increasing 2,3-butanediol production and reducing ethanol subgeneration in the yeast Saccharomyces cerevisiae, Biotechnology for Biofuels, 11: 180
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Juanssilfero, AB., Kahar, P., Amza, RL., Miyamoto, N., Otsuka, H., Matsumoto, H., Kihira, C., Thontowi, A., Yop, Ogino, C., Prasetya, B., Kondo, A. (2018/06) Effect of inoculum size on single-cell oil production from glucose and xylose using oleaginous yeast Lipomyces starkeyi, Journal of Bioscience and Bioengineering, 126(6), 695-702
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Kobayashi, J., Sasaki, D., Kondo, A. (2018/06) A procedure for precise determination of glutathione produced by Saccharomyces cerevisiae, Bio-protocol, 8(12): e2887
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Suffian, I., Wang, J., Faruqu, F., Benitez, J., Nishimura, Y., Ogino, C., Kondo, A., Al-Jamal, K. (2018/06) Engineering Human Epidermal Growth Receptor 2-Targeting Hepatitis B Virus Core Nanoparticles for siRNA Delivery in Vitro and in Vivo, ACS Applied Nano Materials, 1(7), 3269-3282
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Tsuge, Y., Kawaguchi, H., Yamamoto, S., Nishigami, Y., Sota, M., Ogino, C., Kondo, A. (2018/07) Metabolic engineering of Corynebacterium glutamicum for production of sunscreen shinorine, Bioscience, Biotechnology, and Biochemistry, 82(7): 1252-1259 (7月号表紙採用)
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Restu, WK., Nishida, Y., Yamamoto, S., Ishii, J., Maruyama, T. (2018/07) Short oligopeptides for biocompatible and biodegradable supramolecular hydrogels. Langmuir, 34, 8065−8074
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Ohno, R., Teramura, H., Ogino, C., Kondo, A., Takumi, S. (2018/07) Genotypic effects on sugar and by-products of liquid hydrolysates and on saccharification of acid-insoluble residues of from wheat straw, Genes & Genetic Systems, 93, 1-7
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Nakamura, Y., Nishi, T., Noguchi, R., Ito, Y., Watanabe, T., Nishiyama, T., Aikawa, S., Hasunuma, T., Ishii, J., Okubo, Y., Kondo, A. (2018/07) A stable, autonomously replicating plasmid vector containing Pichia pastoris centromeric DNA, Applied and Environmental Microbiology, 84(15), e02882-17
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Morita, K., Suzuki, T., Nishimura, Y., Matsumoto, K., Numako, C., Sato, K., Nakayama, M., Sasaki, R., Ogino, C., Kondo, A. (2018/07) In vivo tissue distribution and safety of polyacrylic acid–modified titanium peroxide nanoparticles as novel radiosensitizers, Journal of Bioscience and Bioengineering, 126(1), 119-125
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Hasunuma, T.*, Matsuda, M., Kato, Y., Vavricka, CJ., Kondo, A. (2018/07) Temperature enhanced succinate production concurrent with increased central metabolism turnover in the cyanobacterium Synechocystis sp. PCC 6803, Metabolic Engineering, 48, 109-120
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Nihei, N., Okamoto, H., Furune, T., Ikuta, N., Sasaki, K., Rimbach, G., Yoshikawa, Y., Terao, K. (2018/8) Dietary α-cyclodextrin modifies gut microbiota and reduces fat accumulation in high-fat-diet-fed obese mice, BioFactors, 44(4), 336-347
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Shimatani, Z., Fujikura, U., Ishii, H., Terada, R., Nishida, K., Kondo, A. (2018/08) Herbicide tolerance-assisted multiplex targeted nucleotide substitution in rice, Data in Brief, 20: 1325-1331
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Eguchi, Y., Makanae, K., Hasunuma, T., Ishibashi, Y., Kito, K., Moriya, H. (2018/08) Estimating the protein burden limit of yeast cells by measuring expression limits of glycolytic proteins, eLife, 7: e34595
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Hama, S., Kihara, M., Noda, H., Kondo, A. (2018/09) Development of cell recycle technology incorporating nutrient supplementation for lignocellulosic ethanol fermentation using industrial yeast Saccharomyces cerevisiae, Biochemical Engineering Journal, 137, 23-29
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Juanssilfero, BA., Kahar, P., Amza, LR., Miyamoto, N., Otsuka, H., Matsumoto, H., Kihira, C., Thontowi, A., Yopi., Ogino, C., Prasetya, B., Kondo, A. (2018/09) Selection of oleaginous yeasts capable of high lipid accumulation during challenges from inhibitory chemical compounds, Biochemical Engineering Journal, 137, 182-191
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Noguchi, Y.*, Kashiwagi, N.*, Uzura, A., Ogino, C., Kondo, A., Ikeda, H., Sota, M. (2018/09) Development of a strictly regulated xylose-induced expression system in Streptomyces, Microbial Cell Factories, 17: 151
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Inokuma, K., Matsuda M., Sasaki, D., Hasunuma, T., Kondo, A. (2018/09) Widespread effect of N-acetyl-D-glucosamine assimilation on the metabolisms of amino acids, purines, and pyrimidines in Scheffersomyces stipitis, Microbial Cell Factories, 17, 153
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Arazoe, T., Kondo, A., Nishida, K. (2018/09) Targeted nucleotide editing technologies for microbial metabolic engineering, Biotechnology Journal, 13(9), 1700596
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Wijaya, H., Sasaki, K., Kahar, P., Yopi, Kawaguchi, H., Sazuka, T., Ogino, C., Prasetya, B., Kondo, A. (2018/10) Repeated ethanol fermentation from membrane-concentrated sweet sorghum juice using the flocculating yeast Saccharomyces cerevisiae F118 strain, Bioresource Technology, 265, 542-547
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Shimatani, Z.*, Fujikura, U.*, Ishii, H., Matsui, Y., Suzuki, M., Ueke, Y., Taoka, K., Terada, R., Nishida, K., Kondo, A. (2018/10) Inheritance of co-edited genes by CRISPR-based targeted nucleotide substitutions in rice, Plant Physiology and Biochemistry, 131: 78-83
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Fujiwara, R., Noda, S., Tanaka, T., Kondo, A. (2018/10) Muconic acid production using gene-level fusion proteins in Escherichia coli, ACS Synthetic Biology, 7(11), 2698-2705
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Okano, K., Honda, K., Taniguchi, H., Kondo, A. (2018/10) De novo design of biosynthetic pathways for bacterial production of bulk chemicals and biofuels, FEMS Microbiology Letters, 365(20), fny215
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Zhang, Y., Nakagawa, K., Shibuya, M., Sasaki, K., Takahashi, T., Shintani, T., Yoshida, T., Kamio, E., Kondo, A., Matsuyama, H. (2018/11) Improved permselectivity of forward osmosis membranes for efficient concentration of pretreated rice straw and bioethanol production, Journal of Membrane Science, 566, 15-24
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Takayama, S., Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Hirata, Y., Matsumoto, T., Tanaka, T., Kondo, A. (2018/11) Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe. Microbial Cell Factories, 17, 176
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Ito, Y., Watanabe, T., Aikawa, S., Nishi, T., Nishiyama, T., Nakamura, Y., Hasunuma, T., Okubo, Y., Ishii, J., Kondo, A. (2018/11) Deletion of DNA ligase IV homolog confers higher gene targeting efficiency on homologous recombination in Komagataella phaffii, FEMS Yeast Research, 18(7), foy074
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Itoh, H., Matsui, M., Miyamura, Y., Takeda, I., Ishii, J., Kumagai, T., Machida, M., Shibata, T., Arita, M. (2018/12) Biosynthesis of Novel Statins by Combining Heterologous Genes from Xylaria and Aspergillus, ACS Synthetic Biology, 7(12), 2783-2789
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Takaishi, T., Wakisaka, K., Vavricka, CJ., Kiyota, H., Izumi, M. (2018/12) Multigram-scale and column chromatography-free synthesis of L-azetidine-2-carboxylic acid for the synthesis of nicotianamine and its derivatives, Heterocycles, 96, 2126-2134
総説・解説
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澁谷真史,中川敬三,佐々木建吾,近藤昭彦,松山秀人, FOプロセスの適用によるバイオエタノール生産の向上, 膜,43(1), 21-26 (2018/01)
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柘植謙爾, 石井純, 荒木通啓, 近藤昭彦, ゲノム合成の潮流のインパクト 微生物による物質生産, 現代化学, 1月号, No.562, <特集>生命をつくる:ゲノム編集の時代, 36-41 (2018/01)
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西田敬二, 進展するゲノム編集, 現代化学, 1月号, No.562, <特集>生命をつくる:ゲノム編集の時代, 26-29 (2018/01)
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若井暁, 微生物腐食を防ぐ新薬剤, 配管技術, vol.60(2), 22-28 (2018/02)
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佐々木建吾, In vitro培養系ヒト大腸菌叢モデルを利用したプレバイオティクスおよびタウリンの影響評価, 日本醸造協会誌, 第113巻, 第2号, 71-78 (2018/02)
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林将也, 岡田茜, 山本久美子, 奥河内知美, 日下知香, 工藤大蔵, 根本理子, 稲垣純子, 広瀬侑, 岡島俊英, 田村隆, 左右田健次, 稲垣賢二, 放線菌Streptomyces sp. 590由来の抗腫瘍性酵素L-メチオニン脱炭酸酵素の遺伝子クローニング,組換え発現,均一精製および性質検討, Vitamins (Japan), 92(3), 113-116 (2018/04)
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若井暁,加熱で活性型になるバイオサイド,BIO INDUSTRY,vol. 35(4),26-35 (2018/04)
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生田直子, 篠原涼平, 佐々木大介, 佐々木建吾, 培養系ヒト腸内細菌叢モデルKUHIMMを利用した食物繊維の影響評価, New Food Industry, Vol.60, No.5, 37-43 (2018/05)
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清田洋正, Vavricka, CJ. シアリダーゼ阻害剤・抗インフルエンザ薬の創出 - スルホシアル酸の展開, 化学, 73, 66-67 (2018/05)
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若井暁,金属中の電子を抜き出して食べる微生物達,環境バイオテクノロジー学会誌,vol. 18(1), 51-56 (2018/07)
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田中勉, 近藤昭彦, 分裂酵母を用いた有機酸生産技術の開発, ケミカルエンジニヤリング, 特集=革新技術が拓く新しい可能性, vol. 63(7), 7-10 (2018/07)
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小林淳平, 酵素を出さない光合成細菌の遺伝子工学的な有用物質生産, 生物工学会誌, vol.96(9), 534-537 (2018/09)
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蓮沼誠久, チャンスを掴むための準備, バイオ系のキャリアデザイン, 生物工学会誌, vol96(10), 598-601 (2018/10)
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猪熊健太郎, 若井暁, 近藤昭彦, 多様な糖を用いた高収率物質生産技術の開発, ケミカルエンジニヤリング, 特集/バイオテクノロジーが拓く新世代, vol.63(11), 43-51 (2018/11)
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佐々木大介, 佐々木建吾, 近藤昭彦, 大澤朗, in vitro培養システムによる食物繊維のヒト腸管細菌叢への影響評価, ルミナコイド研究(日本食物繊維学会会誌), Vol22, No.2, 63-74 (2018/12)
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大重真彦, 高橋俊介, 桂進司, 電界印加による分子・生体分子操作-タンパク質分子の固定化技術-, 静電気学会誌, 42, 168-173 (2018)
著書
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岡野憲司, 田中勉, 本田孝祐, 近藤昭彦, 乳酸菌の遺伝子操作技術の進展, 酵母菌・麹菌・乳酸菌の産業応用展開, 第III編 乳酸菌 第2章, 201-207, シーエムシー出版 (2018/01)
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吉見啓, 宮澤拳, 張斯来, 麹菌の細胞壁 a-1,3-グルカン欠損株による高密度培養と物質高生産への利用, 酵母・麹菌・乳酸菌の産業応用展開, 第二編 麹菌 第9章, 162-167, シーエムシー出版 (2018/01)
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Inokuma, K., Hasunuma, T., Kondo, A. Emerging Areas in Bioengineering:Whole cell biocatalysts using enzymes displayed on yeast cell surface., Chang HN (Ed) Wiley-VCH, 81-92 (2018/01)
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松本拓也, 田中勉, Sortase Aを用いたタンパク質配向固定化技術の開発, 細胞・生体分子の固定化と機能発現, 第3章, 18-25 (2018/04)
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蓮沼誠久, 田村具博, 近藤昭彦, 総論, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 1-9, シーエムシー出版 (2018/06)
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柘植謙爾, 高橋俊介, 近藤昭彦, OGAB法による長鎖DNA合成技術, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第1編 ハイスループット合成・分析・評価技術, 第1章 ハイスループット長鎖DNA合成技術, 19-25, シーエムシー出版 (2018/06)
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石井純, 西晶子, 北野美保, 中村朋美, 庄司信一郎, 秀瀬涼太, 蓮沼誠久, 近藤昭彦, 微生物を用いた物質生産とハイスループット微生物構築技術, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第1編 ハイスループット合成・分析・評価技術, 第2章 ハイスループット微生物構築・評価技術, 39-43, シーエムシー出版 (2018/06)
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蓮沼誠久, スマートセル設計に資するメタボローム解析, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第1編 ハイスループット合成・分析・評価技術, 第3章 オミクス解析技術, 62-68, シーエムシー出版 (2018/06)
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荒木通啓, 白井智量, 新規代謝経路の設計, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第2編 情報解析技術, 第1章 代謝系を設計する情報解析技術, 83-87, シーエムシー出版 (2018/06)
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厨祐喜, 白井智量, 荒木通啓, 代謝モデル構築と代謝経路設計, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第2編 情報解析技術, 第1章 代謝系を設計する情報解析技術, 88-91, シーエムシー出版 (2018/06)
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荒木通啓, 代謝設計に向けた酵素選択, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第2編 情報解析技術, 第1章 代謝系を設計する情報解析技術, 99-103, シーエムシー出版 (2018/06)
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荒木通啓, 伊藤潔人, 武田志津, バイオ生産に資するAI基盤技術, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第2編 情報解析技術, 第5章 知識整理技術, 135-140, シーエムシー出版 (2018/06)
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高久洋暁, 荒木秀雄, 小笠原渉, 田代康介, 蓮沼誠久, 油谷幸代, 矢追克郎, 第9章 油脂酵母による油脂発酵生産性改善へ向けた技術開発, スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第3編 産業応用へのアプローチ, 206-214, シーエムシー出版 (2018/06)
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Nakamura, Y., Kondo, A., Ishii, J., Biosensing techniques in yeast: G-protein signaling and protein-protein interaction assays for monitoring ligand stimulation and oligomer formation of heterologous GPCRs, Peripheral Membrane Proteins, ISBN 978-1-78923-513-5, IntechOpen, Chapter 3, 25-48 (2018/07)
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Matsumoto, T., Tanaka, T., Kondo, A. Sortase A-Assisted Metabolic Enzyme Ligation in Escherichia coli for Enhancing Metabolic Flux. In: Braman J. (eds) Synthetic Biology, Methods in Molecular Biology, vol 1772. pp125-136 Humana Press, New York, NY (2018)
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Wakai, S., Sambongi, Y. Extremophilic enzymes related to energy conversion, Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery, Springer, Makoto Suzuki (Eds.), 275-302 (2018)
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Morita, K., Nishimura, Y., Suzuki, T., Ogino, C., Kondo, A. A cancer treatment strategy that combines the use of inorganic/biocomplex nanoparticles with conventional radiation therapy, Nanoparticle Technology Handbook, Category A - Medical, Cosmetic, Biological, 439-443 (2018)
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Kondo, A. Development of the thermoresponsive magnetic nanoparticle and its deployment in the biotechnology field, Nanoparticle Technology Handbook, Category A - Medical, Cosmetic, Biological, 427-434 (2018)