研究成果
Papers 2022
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Ismail, KSK., Matano, Y., Sakihama, Y., Inokuma, K., Nambu, Y., Hasunuma, T., Kondo, A. (2022/01) Pretreatment of extruded Napier grass by hydrothermal process with dilute sulfuric acid and fermentation using a cellulose-hydrolyzing and xylose-assimilating yeast for ethanol production, Bioresource Technology, 343, 126071
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Kawaguchi, H., Takada, K., Elkasaby, T., Pangestu, R., Toyoshima, M., Kahar, P., Ogino, C., Kaneko, T., Kondo, A. (2022/01) Recent advances in lignocellulosic biomass white biotechnology for bioplastics, Bioresource Technology, 344(B): 126165
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Kato, Y., Inabe, K., Hidese, R., Kondo, A., Hasunuma, T. (2022/01) Metabolomics-based engineering for biofuel and bio-based chemical production in microalgae and cyanobacteria: A review, Bioresource Technology, 344(A): 126196
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Kahar, P., Rachmadona, N., Pangestu, R., Palar, R., Nugroho Adi, DT., Juanssilfero, AB., Yopi, Manurung, I., Hama, S., Ogino, C. (2022/01) An integrated biorefinery strategy for the utilization of palm-oil wastes, Bioresource Technology, 344(B): 126266
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Kobayashi, Y., Inokuma, K., Matsuda, M., Kondo, A., Hasunuma, T. (2022/01) Resveratrol production of a recombinant Scheffersomyces stipitis strain from molasses, Biotechnology Notes, 3, 1-7
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Chen, HQ., Zhang, MM., Xing, Q., Ye, PL., Hasunuma, T., Kondo, A., Zhao, XQ. (2022/01) Improved ethanol fermentation by promoter replacement of zinc responsive genes IPL1, PRP6 and RTC1 in Saccharomyces cerevisiae, Biochemical Engineering Journal, 178, 108274
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Li, YH., Zhang, P., Zhu, DY., Yao, B., Hasunuma, T., Kondo, A., Zhao, XQ. (2022/01) Efficient preparation of soluble inducer for cellulase production and saccharification of corn stover using in-house generated crude enzymes, Biochemical Engineering Journal, 178, 108296
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Kashojiya, S., Lu, Y., Takayama, M., Komatsu, H., Minh, L., Nishida, K., Shirasawa, K., Miura, K., Nonaka, S., Masuda, J., Kondo, A., Ezura, H., Ariizumi, T. (2022/01) Modification of tomato breeding traits and plant hormone signaling by Target-AID, the genome-editing system inducing efficient nucleotide substitution, Horticulture Research, 9, uhab004
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Nishi, T., Ito, Y., Nakamura, Y., Yamaji, T., Hashiba, N., Tamai, M., Yasohara, Y., Ishii, J., Kondo, A. (2022/01) One-step in vivo assembly of multiple DNA fragments and genomic integration in Komagataella phaffii, ACS Synthetic Biology, 11(2), 644-654
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Ratnakomala, S., Kahar, P., Kashiwagi, N., Lee, J., Kudou, M., Matsumoto, H., Apriliana, P., Yopi, Y., Prasetya, B., Ogino, C., Kondo, A. (2022/01) Manno-Oligosaccharide Production from Biomass Hydrolysis by Using Endo-1,4-β-Mannanase (ManNj6-379) from Nonomuraea jabiensis ID06-379, Processes, 10, 269
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Bamba, T., Guirimand, G., Kondo, A., Hasunuma, T. (2022/02) Enzyme display technology for lignocellulosic biomass valorization by yeast cell factories, Current Opinion in Green and Sustainable Chemistry, 33: 100584
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Vavricka, CJ., Takahashi, S., Watanabe, N., Takenaka, M., Matsuda, M., Yoshida, T., Suzuki, R., Kiyota, H., Li, J., Minami, H., Ishii, J., Tsuge, K., Araki, M., Kondo, A., Hasunuma, T. (2022/03) Machine learning discovery of missing links that mediate alternative branches to plant alkaloids, Nature Communications, 13, 1405
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Morita, K., Seike, T., Ishii, J., Matsuda, F., Shimizu, H. (2022/03) Improvement of 2, 3-butanediol production by dCas9 gene expression system in Saccharomyces cerevisiae, Journal of Bioscience and Bioengineering, 133(3), 208-212
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Tominaga, M., Kondo, A., Ishii, J. (2022/04) (Review) Engineering of Synthetic Transcriptional Switches in Yeast, Life, 12, 557
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Okano, K., Sato, Y., Hama, S., Tanaka, T., Noda, H., Kondo, A., Honda, K. (2022/04) L-Lactate oxidase-mediated removal of L-lactic acid derived from fermentation medium for the production of optically pure D-lactic acid, Biotechnology Journal, 17(4), 2100331
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Yamaguchi, A., Maeshige, N., Ma, X., Uemura, M., Noguchi, H., Matsuda, M., Nishimura, Y., Hasunuma, T., Kondo, H., Fujino, H. (2022/04) Pulsed-ultrasound irradiation induces the production of itaconate and attenuates inflammatory responses in macrophages, Journal of Inflammation Research, 15, 2387-2395
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Shirai, T., Kondo, A. (2022/04) In silico design strategies for the production of target chemical compounds using iterative single-level linear programming problems, biomolecules, 12(5), 620
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Kumokita, R., Bamba, T., Inokuma, K., Yoshida, T., Ito, Y., Kondo, A., Hasunuma, T. (2022/05) Construction of an ʟ-Tyrosine chassis in Pichia pastoris enhances aromatic secondary metabolites production from glycerol, ACS Synthetic Biology, 11(6), 2098-2107
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Rachmadona, N., Harada, Y., Amoah, J., Quayson, E., Aznury, M., Hama, S., Kondo, A., Ogino, C. (2022/06) Integrated bioconversion process for biodiesel production utilizing waste from the palm oil industry, Journal of Environmental Chemical Engineering, 10(3), 107550
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Ito, Y., Ishigami, M., Terai, G., Nakamura, Y., Hashiba, N., Nishi, T., Nakazawa, H., Hasunuma, T., Asai, K., Umetsu, M., Ishii, J., Kondo, A. (2022/06) A streamlined strain engineering workflow with genome-wide screening detects enhanced protein secretion in Komagataella phaffii, Communications Biology, 5, 561
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Fujiwara, R., Nakano, M., Hirata, Y., Otomo, C., Nonaka, D., Kawada, S., Nakazawa, H., Umetsu, M., Shirai, T., Noda, S., Tanaka, T., Kondo, A. (2022/07) G6P-capturing molecules in the periplasm of Escherichia coli accelerate the shikimate pathway, Metabolic Engineering, 72, 68-81
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Kahar, P., Itomi, A., Tsuboi, H., Ishizaki, M., Yasuda, M., Kihira, C., Otsuka, H., Azmi, N.b., Matsumoto, H., Ogino, C., Kondo, A. (2022/07) The flocculant Saccharomyces cerevisiae strain gains robustness via alteration of the cell wall hydrophobicity, Metabolic Engineering, 72, 82-96
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Toya, Y., Hirono-Hara, Y., Hirayama, H., Kamata, K., Tanaka, R., Sano, M., Kitamura, S., Otsuka, K., Abe-Yoshizumi, R., Tsunoda, S., Kikukawa, H., Kandori, H., Shimizu, H., Matsuda, F., Ishii, J., Hara, KY. (2022/07) Optogenetic reprogramming of carbon metabolism using light-powering microbial proton pump systems, Metabolic Engineering, 72, 227-236
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Tominaga, M., Miyazaki, K., Hataya, S., Mitsui, Y., Kuroda, S., Kondo, A., Ishii, J. (2022/07) Enhanced squalene production by modulation of pathways consuming squalene and its precursor, Journal of Bioscience and Bioengineering, 134(1), 1-6
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Isogai, S., Tominaga, M., Kondo, A., Ishii, J. (2022/07) Plant flavonoid production in bacteria and yeasts, Frontiers in Chemical Engineering, 4, 880694
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Niimi-Nakamura, S., Kawaguchi, H., Uematsu, K., Teramura, H., Tsuruta, S., Kashiwagi, N., Sugai, Y., Katsuyama, Y., Ohnishi, Y., Ogino, C., Kondo, A. (2022/07) 3-Amino-4-hydroxybenzoic acid production from glucose and/or xylose via recombinant Streptomyces lividans, The Journal of General and Applied Microbiology, 68(2), 109-116
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Li, A., Mitsunobu, H., Yoshioka, S., Suzuki, T., Kondo, A., Nishida, K. (2022/08) Cytosine base editing systems with minimized off-target effect and molecular size, Nature Communications, 13 4531
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Kobayashi, J., Sasaki, D., Hara, KY., Hasunuma, T., Kondo, A. (2022/08) Metabolic engineering of the L-serine biosynthetic pathway improves glutathione production in Saccharomyces cerevisiae, Microbial Cell Factories, 21, 153
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Pangestu, R., Kahar, P., Kholida, LN., Perwitasari, U., Thontowi, A., Fahrurrozi, Lisdiyanti, P., Yopi, Ogino, C., Prasetya, B., Kondo, A. (2022/08) Harnessing originally robust yeast for rapid lactic acid bioproduction without detoxification and neutralization, Scientific Reports, 12, 13645
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Kee, PE., Yim, HS., Kondo, A., Wei Won, SY., Lan, J. C-W., Ng, HS. (2022/08) Evaluation of ionic liquids/salt aqueous biphasic flotation system on recovery of Kytococcus sedentarius TWHKC01 keratinase from crude feedstock, Journal of the Taiwan Institute of Chemical Engineers, 137, 104198
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Chetty, BJ., Inokuma, K., Hasunuma, T., van Zyl, WH., den Haan, R. (2022/09) Improvement of cell-tethered cellulase activity in recombinant strains of Saccharomyces cerevisiae, Applied Microbiology and Biotechnology, 106(18), 6347-6361
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Ito, Y., Ishigami, M., Hashiba, N., Nakamura, Y., Terai, G., Hasunuma, T., Ishii, J., Kondo, A. (2022/09) Avoiding entry into intracellular protein degradation pathways by signal mutations increases protein secretion in Pichia pastoris, Microbial Biotechnology, 15(9), 2364-2378
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Oyama, T., Kato, Y., Hidese, R., Matsuda, M., Matsutani, M., Watanabe, S., Kondo, A., Hasunuma, T. (2022/09) Development of a stable semi-continuous lipid production system of an oleaginous Chlamydomonas sp. mutant using multi-omics profiling, Biotechnology for Biofuels and Bioproducts, 15, 95
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Putra, F.J.N., Kahar, P., Kondo, A., Ogino, C. (2022/10) Valorization of Lignin and Its Derivatives Using Yeast, Processes, 10, 2004
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Fujie, N., Ito, M., Kishida, M., Hirata, Y., Kondo, A., Tanaka, T. (2022/11) Metabolic engineering of Schizosaccharomyces pombe for itaconic acid production, Journal of Biotechnology, 358(10), 111-117
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Hidese, R., Matsuda, M., Kajikawa, M., Osanai, T., Kondo, A., Hasunuma, T. (2022/11) Metabolic and microbial community engineering for four-carbon dicarboxylic acid production from CO2-derived glycogen in the Cyanobacterium Synechocystis sp. PCC6803, ACS Synthetic Biology, 11, 4054-4064
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Sano, M., Tanaka, R., Kamata, K., Hirono-Hara, Y., Ishii, J., Matsuda, F., Hara, KY., Shimizu, H., Toya, Y. (2022/11) Conversion of mevalonate to isoprenol using light energy in Escherichia coli without consuming sugars for ATP supply, ACS Synthetic Biology, 11, 3966-3972
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Alfaro-Sayes, D.A., Amoah, J., Aikawa, S., Matsuda, M., Hasunuma, T., Kondo, A., Ogino, C. (2022/12) Alginate immobilization as a strategy for improving succinate production during autofermentation using cyanobacteria Synechocystis sp. PCC 6803, Biochemical Engineering Journal, 188, 108681
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Otsuka, K., Seike, T., Toya, Y., Ishii, J., Hirono-Hara, Y., Hara, KY., Matsuda, F. (2022/12) Evolutionary approach for improved proton pumping activity of heterologous rhodopsin expressed in Escherichia coli, Journal of Bioscience and Bioengineering, 134(6): 484-490
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Morita, K., Nishimura, Y., Ishii, J., Maruyama, T. (2022/12) Micelle-like nanoassemblies of short peptides create antimicrobial selectivity in a conventional antifungal drug. ACS Applied Nano Materials, 6(2): 1432-1440
総説・解説
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猪熊健太郎, 蓮沼誠久, 進化する酵母細胞表層工学 -バイオインターフェイスの高度利用に向けた技術戦略-, オレオサイエンス, 22(3), 99-105 (2022/03)
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近藤昭彦, 荻野千秋, [特集]「生物機能を利用したモノづくり」に貢献するプロセス強化 バイオエコノミーの展望, 化学工学, 86(4), 151-152 (2022/04)
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蓮沼誠久, 秀瀬涼太, 番場崇弘, [特集]「生物機能を利用したモノづくり」に貢献するプロセス強化 微生物の高速育種を実現するスマートセル創出プラットフォーム, 化学工学, 86(4), 157-160 (表紙採用) (2022/04)
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冨永将大, mRNAワクチン:予防医薬の急先鋒?, 生物工学会誌, 100(4), 190-190 (2022/04)
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田口精一, 高 相昊, 生分解性「多元ポリ乳酸LAHB」の研究ストーリー:乳酸重合酵素誕生・オリゴマー分泌生産発見・膜小胞創発, 生物工学会誌, 100(9), 483-488 (2022/09)
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近藤昭彦, 蓮沼誠久, 秀瀬涼太, 育種技術 -突然変異から代謝工学へ-, 日本生物工学会100年史, 第3章 生物工学の研究100年, 29-31 (2022/10)
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蓮沼誠久, これからの生物育種 -代謝工学による育種のこれから-, 日本生物工学会100年史, 第4章 生物工学のこれから, 58-60 (2022/10)
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藤原良介, 野田修平, 田中勉, 糖の使い分け技術 ・ 代謝制御添加剤を駆使した 微生物発酵生産, 化学工業, 73, 10 (2022/10)
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藤原良介, 野田修平, 田中勉, 大腸菌ペリプラズムでのグルコース-6-リン酸の捕捉は芳香族アミノ酸合成を促進する, バイオサイエンスとインダストリー, 80, 6, 474-475 (2022/11)
著書
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猪熊健太郎,蓮沼誠久,クリーンエネルギーの技術と市場 2022 第9章 バイオマス燃料生産の技術動向,シーエムシー出版,84-91 (2022/02)