研究成果
Papers 2017
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Nishimura, Y., Ezawa, R., Ishii, J., Ogino, C., Kondo, A. (2017/01) Affibody-displaying bio-nanocapsules effective in EGFR, typical biomarker, expressed in various cancer cells., Bioorganic & Medicinal Chemistry Letters, 27(2), 336-341
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Ghobadi, N., Ogino, C., Yamabe, K., Ohmura, N. (2017/01) Characterizations of the submerged fermentation of Aspergillus oryzae using a Fullzone impeller in a stirred tank bioreactor., Journal of Bioscience and Bioengineering, 123(1), 101-108
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Kono, T., Mehrotra, S., Endo, C., Kizu, N., Matsuda, M., Kimura, H., Mizohata, E., Inoue, T., Hasunuma, T., Yokota, A., Matsumura, H., Ashida, H. (2017/01) A RuBisCO-mediated carbon metabolic pathway in methanogenic archaea., Nature Communications, 8 : 14007
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Ho, SH., Chen, YD., Chang, CY., Lai, YY., Chen, CY., Kondo, A., Ren, NQ., Chang, JS. (2017/01) Feasibility of CO2 mitigation and carbohydrate production by microalga Scenedesmus obliquus CNW-N used for bioethanol fermentation under outdoor conditions : Effects of seasonal changes. Biotechnology for Biofuels, 10 : 27
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Qing, X., Yan, HM., Ni, ZY., Vavricka, CJ., Zhang, ML., Shi, QW., Gu, YC., Kiyota, H. (2017/01) Chemical and pharmacological research on the plants from genus Ajuga, Heterocyclic Communications, 23(4), 245
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Takenaka, M., Okumura, Y., Amino, T., Miyachi, Y., Ogino, C., Kondo, A. (2017/02) DNA-duplex linker for AFM-SELEX of DNA aptamer against human serum albumin. Bioorganic and Medicinal Chemistry Letters, 27(4), 954-957
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Zhang. F., Wang, HW., Tominaga, K., Hayashi, M., Hasunuma, T., Kondo, A. (2017/02) Application of THz vibrational spectroscopy to molecular characterization and the theoretical fundamentals: an illustration using saccharide molecules., Chemistry - An Asian Journal, 12(3), 324-331
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Hsu, H., Hasunuma, T., Araki, M., Yoshida, T., Hori, Y., Murata, M., Kondo, A. (2017/02) Application of LC-MS/MS analysis for time-lapse amino acid metabolomics in CHO cell culture., Shimadzu Journal, 5 (1), 17-21
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Okano, K., Hama, S., Kihara, M., Noda, H., Tanaka, T., Kondo, A. (2017/03) Production of optically pure D-lactic acid from brown rice using metabolically engineered Lactobacillus plantarum., Applied Microbiology and Biotechnology, 101(5), 1869-1875
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Takenaka, M., Kobayashi, T., Inokuma, K., Hasunuma, T., Maruyama, T., Ogino, C., Kondo, A. (2017/03) Mapping of endoglucanases displayed on yeast cell surface using atomic force microscopy., Colloids and Surfaces B: Biointerfaces, 151, 134-142
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Bin Mohamed Suffian, I. F., Wang, J. T-W., Hodgins, N. O., Klippstein, R., Garcia-Maya, M., Brown, P., Nishimura, Y., Heidari, H., Bals, S., Sosabowski, J., Ogino, C., Kondo, A., Al-Jamal, K. T. (2017/03) Engineering hepatitis B virus core particles for targeting HER2 receptors in vitro and in vivo., Biomaterials, 120, 126-138
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Bin Mohamed Suffian, I. F., Mitla, GM., Paul, B., Bui, T., Nishimura, Y., Amir, R. B. M. J. P., Ogino, C., Kondo, A., Al-Jamal, K.T. (2017/03) Yield optimisation of hepatitis B virus core particles in E. coli expression system for drug delivery applications. Scientific Reports, 7: 43160
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Hsu, H., Araki, M., Mochizuki, M., Hori, Y., Murata, M., Kahar, P., Yoshida, T., Hasunuma, T., Kondo, A. (2017/03) A systematic approach to time-series metabolite profiling and RNA-seq analysis of Chinese hamster ovary cell culture, Scientific Reports, 7:43518
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Kuribayashi, A., Fujii, S., Masanari, M., Yamanaka, M., Wakai, S., Sambongi, Y. (2017/03) Difference in NaCl tolerance of membrane-bound 5’-nucleotidases purified from deep-sea and brackish water Shewanella species. Extremophiles, 21(2), 357-368
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Kobayashi, J., Sasaki, D., Hara, K.Y., Hasunuma, T., Kondo, A. (2017/03) Enzymatic improvement of mitochondrial thiol oxidase Erv1 for oxidized glutathione fermentation by Saccharomyces cerevisiae, Microbial Cell Factories, 16:44
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Nagarajan, D., Lee, DJ., Kondo, A., Chang, JS. (Review) (2017/03) Recent insights into biohydrogen production by microalgae - from biophotolysis to dark fermentation. Bioresource Technology, 227, 373-387
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Amoah, J., Quayson, E., Hama, S., Yoshida, A., Hasunuma, T., Ogino, C., Kondo, A. (2017/03) Simultaneous conversion of free fatty acids and triglycerides to biodiesel by immobilized Aspergillus oryzae expressing Fusarium heterosporum lipase., Biotechnology Journal, 12(3), 1600400
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Fujii, S., Oki, H., Kawahara, K., Yamane, S., Yamanaka, M., Maruno, T., Kobayashi, Y., Masanari, M., Wakai, S., Nishihara, H., Ohkubo, T., Sambongi, Y. (2017/04) Structural and functional insights into thermally stable cytochrome c' from a thermophile. Protein Science., 26, 737-748
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Ho, SH., Nakanishi, A., Kato, Y., Yamasaki, H., Chang, JS., Misawa, N., Hirose, Y., Minagawa, J., Hasunuma, T.*, Kondo, A. (2017/04) Dynamic metabolic profiling together with transcription analysis reveals salinity-induced starch-to-lipid biosynthesis in alga Chlamydomonas sp. JSC4, Scientific Reports, 4;7: 45471
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Shibuya, M., Yasukawa, M., Sasaki, K., Tanaka, Y., Takahashi, T., Kondo, A., Matsuyama, H. (2017/05) Up-concentration of sugars in pretreated-rice straw by an osmotic pressure-driven method. Biochemical Engineering Journal, 121, 13-16
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Wakai, S., Abe, A., Fujii, S., Nakasone, K., Sambongi, Y. (2017/05) Pyrophosphate hydrolysis in the extremely halophilic archaeon Haloarcula japonica is catalyzed by a single enzyme with a broad ionic strength range. Extremophiles, 21: 471-477
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Eguchi, Y., Kato, T., Tanaka, T., Maruyama, T. (2017/05) A DNA-gold nanoparticle hybrid hydrogel network prepared by enzymatic reaction. Chemical Communications, 53, 5802-5805
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Yamada, R., Nakashima, K., Asai-Nakashima, N., Tokuhara, W., Ishida, N., Katahira, S., Kamiya, N., Ogino, C., Kondo, A. (2017/05) Direct ethanol production from ionic liquid-pretreated lignocellulosic biomass by cellulase-displaying yeasts., Applied Biochemistry and Biotechnology, 182(1), 229–237
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Shimatani, Z., Kashojiya, S., Takayama, M., Terada, R., Arazoe, T., Ishii, H., Teramura, H., Yamamoto, T., Komatsu, H., Miura, K., Ezura, H., Nishida, K., Ariizumi, T., Kondo, A. (2017/05) Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion, Nature Biotechnology, 35(5), 441-443
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Fukutani, Y., Ishii, J., Kondo, A., Ozawa, T., Matsunami, H., Yohda, M. (2017/06) Split luciferase complementation assay for the analysis of G protein-coupled receptor ligand response in Saccharomyces cerevisiae. Biotechnology and Bioengineering, 114(6): 1354-1361
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Liu, Z., Inokuma, K., Ho, SH., den Haan, R., van Zyl, W.H., Hasunuma, T., Kondo, A. (2017/06) Improvement of ethanol production from crystalline cellulose via optimizing cellulase ratios in cellulolytic Saccharomyces cerevisiae. Biotechnology and Bioengineering, 114(6), 1201-1207
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Ryo, S., Ishii, J., Matsuno, T., Nakamura, Y., Matsubara, D., Tominaga, M., Kondo, A. (2017/06) Positive feedback genetic circuit incorporating a constitutively active mutant Gal3 into yeast GAL induction system., ACS Synthetic Biology, 6(6), 928-935
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Arazoe, T., Nishida, K., Kondo, A. (2017/06) Targeted nucleotide substitution in mammalian cell by Target-AID, Bio-protocol, 7: 11
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Shibuya, M., Sasaki, K., Tanaka, Y., Yasukawa, M., Takahashi, T., Kondo, A., Matsuyama, H. (2017/07) Development of combined nanofiltration and forward osmosis process for production of ethanol from pretreated rice straw. Bioresource Technology, 235, 405-410
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Kobayashi, S., Fujii, S., Koga, A., Wakai, S., Matsubayasi, N., Sambongi, Y. (2017/07) Pseudomonas aeruginosa cytochrome c551 denaturation by five systematic urea derivatives that differ in the alkyl chain length. Bioscience, Biotechnology, and Biochemistry., 81: 1274-1278
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Sasaki, K., Sasaki, D., Okai, N., Tanaka, K., Nomoto, R., Fukuda, I., Yoshida, K., Kondo, A., Osawa, R. (2017/07) Taurine does not affect the composition, diversity, or metabolism of human colonic microbiota simulated in a single-batch fermentation system, PLOS ONE, 12(7), e0180991
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Kawaguchi, H., Katsuyama, Y., Danyao, D., P. Kahar, Nakamura-Tsuruta, S., Teramura, H., Wakai, K., Yoshihara K., Minami, H., Ogino, C., Ohnishi, Y., Kondo, A. (2017/07) Caffeic acid production by simultaneous saccharification and fermentation of kraft pulp using recombinant Escherichia coli, Appl Microbiol Biotechnoliol, 101(13), 5279–5290
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Teramura, H., Sasaki, K., Kawaguchi, H., Matsuda, F., Kikuchi, J., Shirai, T., Sazuka, T., Yamasaki, Y., Takumi, S., Ogino, C., Kondo, A. (2017/08) Differences in glucose yield of residues from among varieties of rice, wheat, and sorghum after dilute acid pretreatment. Bioscience Biotechnology and Biochemistry, 81(8), 1650-1656
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Osada, T., Maeda, M., Tanabe, C., Furuta, K., Vavricka, CJ., Sasaki, E., Okano, M., Kimura, Y. (2017/08) Glycoform of a newly identified pollen allergen, Cha o 3, from Chamaecyparis obtusa (Japanese cypress, Hinoki). Carbohydrate Research, 448, 18-23
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Sasaki, K., Tsuge, Y., Kawaguchi, H., Yasukawa, M., Sasaki, D., Sazuka, T., Kamio, E., Ogino, C., Matsuyama, H., Kondo, A. (2017/08) Sucrose purification and repeated ethanol production from sugars remaining in sweet sorghum juice subjected to a membrane separation process, Applied Microbiology and Biotechnology, 101(15): 6007-6014
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Noda, S., Kondo, A. (Review) (2017/08) Recent advances in microbial production of aromatic chemicals and derivatives, Trends in Biotechnology, 35(8), 785-796
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Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Takayama, S., Matsumoto, T., Tanaka, T., Kondo, A. (2017/08) Metabolic engineering of Schizosaccharomyces pombe via CRISPR-Cas9 genome editing for lactic acid production from glucose and cellobiose. Metabolic Engineering Communications, 5, 60-67
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Fukuda, N., Kaishima, M., Ishii, J., Honda, S. (2017/08) Positive detection of GPCR antagonists using a system for inverted expression of a fluorescent reporter gene. ACS Synthetic Biology, 6(8), 1554-1562
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Vavricka, CJ., Muto, C., Hasunuma, T., Kimura, Y., Araki, M., Wu, Y., Gao, GF., Ohrui, H., Izumi, M., Kiyota, H. (2017/08) Synthesis of sulfo-sialic acid analogues: potent neuraminidase inhibitors in regards to anomeric functionality, Scientific Reports, 7(1): 8239
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Nambu-Nishida, Y., Nishida, K., Hasunuma, T., Kondo, A. (2017/08) Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strain, Scientific Reports, 7(1): 8993
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Wu, YB., Wang, YZ., Ni, ZY., Qing, X., Shi, QW., Sauriol, F., Vavricka, CJ., Gu, YC., Kiyota, H. (2017/09) Xylomexicanins I and J: limonoids with unusual B/C rings from xylocarpus granatum. Journal of Natural Products, 80(9), 2547-2550
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Ueno, Y., Aikawa, S., Niwa, K., Abe, T., Murakami, A., Kondo, A., Akimoto, S. (2017/09) Variety in excitation energy transfer processes from phycobilisomes to photosystems ⅠandⅡ, Photosynthesis Research, 133(1-3), 235-243
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Onishi, A., Aikawa, S., Kondo, A., Akimoto, S. (2017/09) Energy transfer in Anabaena variabilis Filaments under nitrogen-depleted and nitrogen-enriched conditions studied by time-resolved fluorescence, Photosynthesis research, 133(1-3), 317-326
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Morita, K., Nomura, Y., Ishii, J., Matsuda, F., Kondo, A., Shimizu, H. (2017/09) Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner-Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production, Journal of Bioscience and Bioengineering, 124(3), 263-270
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Mitsunobu, H., Teramoto, J., Nishida, K., Kondo, A. (Review)(2017/10) Beyond native Cas9: manipulating genomic information and function, Trends in Biotechnology, 35(10), 983-996
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Mert, MJ., Rose, SH., la Grange, DC., Bamba, T., Hasunuma, T., Kondo, A., van Zyl, WH. (2017/10) Quantitative metabolomics of a xylose‑utilizing Saccharomyces cerevisiae strain expressing the Bacteroides thetaiotaomicron xylose isomerase on glucose and xylose, Journal of Industrial Microbiology and Biotechnology, 44(10), 1459-1470
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Morita, R., Teramura, H., Ogino, C., Kondo, A., Fukayama, H. (2017/10) Overexpression of CO2-responsive CCT protein, a key regulator of starch synthesis strikingly increases the glucose yield from rice straw for bioethanol production, Plant Production Science, 20(4), 441-447
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Noda, S., Shirai, T., Mori, Y., Oyama, S., Kondo, A. (2017/10) Engineering a synthetic pathway for maleate in Escherichia coli, Nature Communications, 8(1): 1153
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Osumi, K., Matsuda, S., Fujimura, N., Matsubara, K., Kitago, M., Itano, O., Ogino, C., Shimizu, N., Obara, H., Kitagawa, Y. (2017/11) Acceleration of wound healing by ultrasound activation of TiO2 in Escherichia coli-infected wounds in mice., Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105(8), 2344-2351
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Takenaka, M., Amino, T., Miyachi, Y., Ogino, C., Kondo, A. (2017/11) Bear-trap sensing of somatostatin via split aptamers and atomic force microscopy, Sensors & Actuators: B. Chemical, 252, 600-605
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Takenaka, M., Amino, T., Miyachi, Y., Ogino, C., Kondo, A. (2017/11) Screening and evaluation of aptamers against somatostatin, and sandwich-like monitoring of somatostatin based on atomic force microscopy, Sensors & Actuators: B. Chemical, 252, 813-821
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Hara, Y. K., Kobayashi, J., Yamada, R., Sasaki, D., Kuriya, Y., Hirono-Hara, Y., Ishii, J., Araki, M., Kondo, A. (2017/11) Transporter Engineering in Biomass Utilization by Yeast, FEMS Yeast Research, 17(7), fox061
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N. Rahmani, Kashiwagi, N., Lee, J., Niimi-Nakamura, S., Matsumoto, H., P. Kahar, Lisdiyanti, P., Yopi, Y., Prasetya, B., Ogino, C., Kondo, A. (2017/12) Mannan endo-1,4-β-mannosidase from Kitasatospora sp. isolated in Indonesia and its potential for production of mannooligosaccharides from mannan polymers, AMB Express, 7(1): 100
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Okai, N., Masuda, T., Takeshima, Y., Tanaka, K., Yoshida, K., Miyamoto, M., Ogino, C., Kondo, A. (2017/12) Biotransformation of ferulic acid to protocatechuic acid by Corynebacterium glutamicum ATCC 21420 engineered to express vanillate O-demethylase, AMB Express, 7(1): 130
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Wakai, S., Arazoe, T., Ogino, C., Kondo, A. (Review)(2017/12) Future insights in fungal metabolic engineering. Bioresource Technology, 245, 1314-1326
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Matsumoto, T., Tanaka, T., Kondo, A. (Review)(2017/12) Engineering metabolic pathways in Escherichia coli for constructing a “microbial chassis” for biochemical production. Bioresource Technology, 245, 1362-1368
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A. Prima, Hara, Y. K., A. C. Djohan, Kashiwagi, N., P. Kahar, Ishii, J., Nakayama, H., Okazaki, F., B. Prasetya, Kondo, A., Yopi, Ogino, C. (2017/12) Glutathione production from mannan-based bioresource by mannanase/mannosidase expressing Saccharomyces cerevisiae, Bioresource Technology, 245, 1400-1406
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Amoah, J., Ishizue, N., Ishizaki, M., Yasuda, M., Takahashi, K., Ninomiya, K., Yamada, R., Kondo, A., Ogino, C. (2017/12) Development and evaluation of consolidated bioprocessing yeast for ethanol production from ionic liquid-pretreated bagasse, Bioresource Technology, 245, 1413-1420
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P. Kahar, E. I. Riyanti, Otsuka, H., Matsumoto, H., Kihira, C., Ogino, C., Kondo, A. (2017/12) Challenges of non-flocculating Saccharomyces cerevisiae haploid strain against inhibitory chemical complex for ethanol production, Bioresource Technology, 245, 1436-1446
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Khatun, MM., Yu, X., Kondo, A., Bai, F., Zhao, X. (2017/12) Improved ethanol production at high temperature by consolidated bioprocessing using Saccharomyces cerevisiae strain engineered with artificial zinc finger protein, Bioresource Technology, 245, 1447-1454
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Kato, Y., Ho, SH., Vavricka, CJ., Chang, JS., Hasunuma, T., Kondo, A. (2017/12) Evolutionary engineering of salt-resistant Chlamydomonas sp. strains reveals salinity stress-activated starch-to-lipid biosynthesis switching, Bioresource Technology, 245, 1484-1490
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Kashiwagi, N., Ogino, C., Kondo, A. (Review)(2017/12) Production of chemicals and proteins using biomass-derived substrates from a Streptomyces host, Bioresource Technology, 245, 1655-1663
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Kawaguchi, H., Ogino, C., Kondo, A. (Review)(2017/12) Microbial conversion of biomass into bio-based polymers, Bioresource Technology, 245, 1664-1673
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Imao, K., Konishi, R., Kishida, M., Hirata, Y., Segawa, S., Adachi, N., Matsuura, R., Tsuge, Y., Matsumoto, T., Tanaka T., Kondo, A. (2017/12) 1,5-Diaminopentane production from xylooligosaccharides using metabolically engineered Corynebacterium glutamicum displaying beta-xylosidase on the cell surface. Bioresource Technology, 245, 1684-1691
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Wang, Y., Ho, SH., Yen, HW., Nagarajan, D., Ren, NQ., Li, S., Hu, Z., Lee, DJ., Kondo, A., Chang, JS. (Review)(2017/12) Current advances on fermentative biobutanol production using third generation feedstock, Biotechnology Advances, 35(8), 1049-1059
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Onodera, K., Hama, S., Yoshida, Y., Noda, H., Kondo, A. (2017/12) Development of fed-batch process for high-yielding β-glucosidase displayed on cell surface of industrial yeast Saccharomyces cerevisiae, Biochemical Engineering Journal, 128, 195-200
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J. Amoah, Ho, SH., Hama, S., Yoshida, A., Nakanishi, A., Hasunuma, T., Ogino, C., Kondo, A. (2017/12) Conversion of Chlamydomonas sp. JSC4 lipids to biodiesel using Fusarium heterosporum lipase-expressing Aspergillus oryzae whole-cell as biocatalyst, Algal Research, 28, 16-23
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Inokuma, K., Iwamoto, R., Bamba, T., Hasunuma, T., Kondo, A. (2017/12) Improvement of xylose fermentation ability under heat and acid co-stress in Saccharomyces cerevisiae using genome shuffling technique, Frontiers in Bioengineering and Biotechnology, 5, 81
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Yoshida, Y., Kuroiwa, H., Shimada, T., Yoshida, M., Ohnuma, M., Fujiwara, T., Imoto, Y., Yagisawa, F., Nishida, K., Hirooka, S., Misumi, O., Mogi, Y., Akakabe, Y., Matsushita, K., Kuroiwa, T. (2017/12) Glycosyltransferase MDR1 assembles a dividing ring for mitochondrial proliferation comprising polyglucan nanofilaments, Proceedings of the National Academy of Sciences of the United States of America, 114(50), 13284-13289
総説・解説
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岡野憲司, 濵真司, 田中勉, 野田秀夫, 近藤昭彦, 未利用バイオマスからのD-乳酸生産に向けた乳酸菌の代謝工学研究, JATAFFジャーナル, Vol.5, No.3, 33-37 (2017/03)
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川口秀夫, 近藤昭彦, リグノセルロース系バイオマスからのバイオモノマー発酵生産, ケミカルエンジニヤリング,Vol.62, No.3, 13-20 (2017/03)
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中村泰之, 伊藤洋一郎, 梅津光央, 石井純, 近藤昭彦, 低分子抗体医薬の開発展望, バイオインダストリー, Vol.34, No.6, 54-62 (2017/06)
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西田敬二, 島谷善平, 近藤昭彦, デアミナーゼを用いたゲノム編集, 植物の生長調節, 52(1), 15-18 (2017/06)
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佐々木建吾, 星奈美子, 16S rRNA遺伝子から見る腸内細菌叢の魅力, 生物工学会誌, 第95巻, 第7号, 397-400 (2017/07)
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近藤昭彦, バイオテクノロジー革新によるバイオプラスチック研究開発の加速, バイオプラジャーナル, No.65, 巻頭 (2017/07)
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近藤昭彦, バイオリファイナリー技術の最近の進歩, アグリバイオ, 11月号, vol.1(12), 総論(2017/11)
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荻野千秋, 農業残さを用いたバイオリファイナリー, アグリバイオ, 11月号, vol.1(12), 19-23(2017/11)
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蓮沼誠久, バイオリファイナリー実現を加速する先端バイオ技術と情報技術の融合, アグリバイオ, 11月号, vol.1(12), 24-29(2017/11)
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石田亘広, 神谷典穂, 荻野千秋, 大西徹, Ionic Liquid-based Consolidated Bioprocessing (i-CBP) for Cellulosic Ethanol Production イオン液体を利用したエタノール生産プロセス, R&D Review of Toyota CRDL, 48巻4号, 特集 低炭素社会を目指した内燃機関の挑戦, 55-64 (2017/12)
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西村勇哉,森田健太,鈴木貴弘,荻野千秋,近藤昭彦,無機とバイオの融合ナノ粒子によるがん治療戦略,粉砕,No.60, 13-19(2017)
著書
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Tsuge, Y., Kondo, A., Production of platform chemicals from sustainable resources: Production of amino acids(L-glutamic acid and L-lysine) from biomass, Feng Z (Ed) Springer, 437-455 (2017)