発表論文

TOP 発表論文 Papers 2025

研究成果

Papers 2025

  1. Aoki, R., Kumagawa, E., Kamata, K., Ago, H., Sakai, N., Hasunuma, T., Taoka, N., Ohta, Y., Kobayash, S. (2025/01) Engineering of acyl ligase domain in nonribosomal peptide synthetases to change fatty acid moieties of lipopeptides, Communications Chemistry, 8:17

  2. Tanaka, K., Yukawa, T., Bamba T., Wakiya, M., Kumokita, R., Jin Y.S., Kondo, A., Hasunuma, T.*(2025/01) Engineering Saccharomyces cerevisiae for growth on xylose using an oxidative pathway, Applied Microbiology and Biotechnology, 109, 30

  3. Apriliana, P., Kahar, P., Rachmadona, N., Restu, W. K., Kondo, A., Ogino, C. (2025/01). Lipid Production in Streptomyces jeddahensis Is Enhanced by Glucose and Fatty Acid Derivatives, with Temperature Variations Influencing Gene Expression and Biosynthesis. Fermentation, 11(2), 45.

  4. Zain, N.-A. A., Tan, K. L., Kahar, P., Ogino, C. (2025/01). Lipid Production from Palm Acid Oil (PAO) as a Sole Carbon Source by Meyerozyma guilliermondii. Processes, 13(2), 311.

  5. Tasia, W., Washio, A., Yamate, K., Morita, K., Mori, Y., Kahar, P., Sasaki, R., Ogino, C. (2025/01). Catalase-Knockout Complements the Radio-Sensitization Effect of Titanium Peroxide Nanoparticles on Pancreatic Cancer Cells. Molecules, 30(3), 629.

  6. Wang, Z., Zeng, D., Zhu, Y., Zhou, M., Kondo, A., Hasunuma, T., Zhao, X. (2025/02) Fermentation design and process optimization strategy based on machine learning ML-BASED FERMENTATION DESIGN AND OPTIMIZATION, BioDesign Research, 100002

  7. Tanaka, K., Lan, J.CW., Kondo, A., Hasunuma T.* (2025/03) Metabolic engineering and cultivation strategies for efficient production of fucoxanthin and related carotenoids. Applied Microbiology and Biotechnology, 109, 57

  8. Kato, Y., Kamasaka, K., Matsuda, M., Koizumi, H., Ohbayashi, R., Ashida, H., Kondo, A., Hasunuma, T. (2025/03) Metabolic analysis reveals the contribution of mechanosensitive channel MscM to extracellular release of glutamate in glycogen-deficient Synechococcus elongatus, Journal of Bioscience and Bioengineering, 139(3), 187-193

  9. Rahmasari, D., Kahar, P., de Oliveira, A. V., Putra, F. J. N., Kondo, A., Ogino, C. (2025/03). Factors Affecting D-Lactic Acid Production by Flocculant Saccharomyces cerevisiae Under Non-Neutralizing Conditions. Microorganisms, 13(3), 618.

  10. Mitsunobu, H., Kita, Y., Nambu-Nishida, Y., Miyazaki, S., Nakajima, K., Taoka, K., Kondo, A., Nishida, K. (2025/04) Development of a highly efficient base editing system for Lactobacilli to improve probiotics and dissect essential functions Applied Microbiology and Biotechnology, 109(1), 96

  11. Tasia, W., Kawamoto, K., Morita, K., Mori, Y., Kahar, P., Sasaki, R., Ogino, C. (2025/04). Selective Interaction and Radio-Sensitizing Effect of Rutin-G-Modified Titanium Peroxide Nanoparticles on Breast Cancer Cells. Preprints.org

  12. Nonaka, D., Kishida, M., Hirata, Y., Mori, A., Kondo, A., Mori, Y., Noda, S., Tanaka, T.* (2025/04) Metabolic engineering for resveratrol production based on modularization of metabolic pathways in Escherichia coli, Journal of Agricultural and Food Chemistry, 73, 11878-11888

  13. Tominaga, M., Kawakami, K., Ogawa, H., Nakamura, T., Kondo, A., Ishii, J. (2025/05) Production of borneol, camphor, and bornyl acetate using engineered Saccharomyces cerevisiae. Metabolic Engineering Communications, 20, e00259

  14. Chen, J., Vavricka, CJ., Wei, S., Nakazawa, Y., Matsumoto, Y., Chen, H., Tang, Y., Liang, J., Chen, J., Huang, Y., Noguchi, K., Hasunuma, T., Guan, H., Li, J., Liao, C., Han, Q. (2025/05)
    3,4-Dihydroxyphenylacetaldehyde synthase evolved an ordered structure to deliver oxygen to pyridoxal 5'-phosphate for cuticle assembly in the mosquito Aedes aegypti, Nature Communications, 16, 4486

  15. Nonaka, D., Kishida,M., Hirata, Y., Mori, A., Kondo, A., Mori, Y., Noda, S., Tanaka,T.* (2025/05)
    Modular pathway engineering for enhanced production of para-aminobenzoic acid and 4-amino-phenylalanine in Escherichia coli via glucose/xylose co-utilization, Applied and Environmental Microbiology, 91, e02468-24

  16. Hidese, R., Sakai, K., Takenaka, M., Fushimi, K., Kudo, H., Tanaka, K., Nasuno, R., Vavricka, CJ.,Kondo, A., Hasunuma, T. (2025/06) Identification of subfamily specific residues within highly active and promiscuous alcohol dehydrogenases, ACS Catalysis, 15, 11931-11943

  17. Mori, A., Hirata, Y., Kishida, M., Nonaka, D., Kondo, A., Mori, Y., Noda, S., Tanaka, T.* (2025/09) Metabolic engineering of Escherichia coli for 4-nitrophenylalanine production via the 4-aminophenylalanine synthetic pathway, Metabolic Engineering, 91, 171-180

  18. Kaneko, S., Fukushima, H., Nakahama, M., Tsuge, K., Ishii, J., Aizawa, Y., Itaya, M., Kondo, A. (2025/09) Versatile Methodology for Efficient Large-sized DNA Delivery Between Microorganisms Without In vitro Purification, Journal of Molecular Biology, 437(17), 169289

  19. Inabe, K., Hidese, R., Kato, Y., Matsuda, M., Yoshida, T., Matsumoto, K., Kondo, A., Sato, S., Hasunuma, T. Introduction of acetyl-phosphate bypass and increased culture temperatures enhanced growth-coupled poly-hydroxybutyrate production in the marine cyanobacterium Synechococcus sp. PCC7002, Metabolic Engineering, in press

  20. Fushimi, K., Nakai, Y., Nishi, A., Suzuki, R., Ikegami, M., Nimura, R., Tomono, T., Hidese, R., Yasueda, H., Tagawa, Y., Hasunuma, T. Development of the Autonomous Lab system to support biotechnology research, Scientific Reports, in press

  21. Moreno,D.S., Cunha, J., Luís D. R. Melo, Tanaka, K., Bamba, T., Hasunuma, T., Azeredo, J., Domingues, L. CRISPR-Cas9 engineered Saccharomyces cerevisiae for endolysin delivery to combat Listeria monocytogenes, Applied Microbiology and Biotechnology, in press

  22. Hisatomi, A., Yoshida, T., Hasunuma,T., Ohkuma, M., Sakamoto, M. Difficult-to-culture microorganisms specifically isolated using the liquid-liquid co-culture method, Microbiology, in press

総説・解説

  1. 松本 圭司, バイオものづくりを志す若者にエール, 生物工学会誌, 103(2), 49 (2025/02)

  2. 石井 純, バイオものづくりに向けた酵母の発現制御・センシング基盤の開発と応用, 生物工学会誌, 103(3), 104-111 (2025/03)

  3. 番場崇弘, 棟方涼介, 矢﨑一史, 蓮沼誠久 プロポリス生理活性成分アルテピリンCの酵母による生産, バイオサイエンスとインダストリー(B&I), vol.83(3), 246-247 (2025/05)

  4. Kahar, P., Zain, N. A. A., Pangestu, R., Ogino, C. Important Key Points Regarding the Circular Bioeconomy in the Palm Oil Industry: Current Practices and Future Perspectives, The Palm Oil Export Market: Trends, Challenges, and Future Strategies for Sustainability, 183-192(2025/3)

著書

  1. 蓮沼誠久, 第10章 循環型未来社会への取組み -6.バイオ燃料, 応用微生物学 第4版, 文永堂出版, 180-323 (2025/03)

  2. 田中勉, 第5章 微生物の代謝 -2.発酵, 応用微生物学 第4版, 文永堂出版, 88-94 (2025/03)

Chen J, Vavricka CJ, Wei S, Nakazawa Y, Matsumoto Y, Chen H, Tang Y, Liang J, Chen J, Huang Y, Noguchi K, Hasunuma T, Guan H, Li J, Liao C, Han Q