研究成果
Papers 2023
-
Takenaka, M., Yoshida, T., Yoshida, E., Ono, S., Horie, S., Vavricka, CJ., Hiratani, M., Tsuge, K., Ishii, J., Hayakawa, Y., Kondo, A., Hasunuma, T. (2023/01) Online SFE-SFC-MS/MS colony screening: a high-throughput approach for optimizing (-)-limonene production, Journal of Chromatography B, 1215, 123588
- Ng, HS., Wan, PK., Kondo, A., Chang, JS., Lan, JCW. (2023/01) Production and recovery of ectoine: a review of current state and future prospects, Processes 11(2), 339
-
Alfaro-Sayes, DA., Amoah, J., Rachmadona, N., Hama, S., Hasunuma, T., Kondo, A., Ogino, C. (2023/01) Enhanced growth and lipid productivity by living Chlorella sorokiniana immobilized in Ca-alginate beads, Journal of Physics: Energy, 5, 014019
- Jagadeesh, V., Yoshida, T., Uraji, M., Okahashi, N., Matsuda, F., Vavricka, CJ., Tsuge, K., Kondo, A. (2023/01) Simple and Rapid Non-ribosomal Peptide Synthetase Gene Assembly Using the SEAM-OGAB Method, ACS Synthetic Biology, 12(1):305-318
- Zhang, S., Guo, F., yang, Q., Jiang, Y., Yang, S., Ma, J., Xin, F., Hasunuma, T., Kondo, A., Zhang, W., Jiang, M. (2023/01) Improving methanol assimilation in Yarrowia lipolytica via systematic metabolic engineering combined with compartmentalization, Green Chemstry, 25(1), 183-195
-
Adachi, M., Sugimoto, H., Nishimura, Y., Morita, K., Ogino, C., Fujii, M. (2023/01) Fluorophore-decorated mie resonant silicon nanosphere for scattering/fluorescence dual-mode imaging, small, 2207318
-
Vikromvarasiri, N. Noda, S., Shirai, T., Kondo, A. (2023/01) Investigation of two metabolic engineering approaches for (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis, Journal of Biological Engineering, 17(1), 3
-
Risanto, R., Nugroho Adi, Dt., Fajriutami, T., Teramura, H., Fatriasari, W., Hermiati, E., Kahar, P., Kondo, A., Ogino, C. (2023/02) Pretreatment with dilute maleic acid enhances the enzymatic digestibility of sugarcane bagasse and oil palm empty fruit bunch fiber, Bioresource Technology, 369, 128382
-
Yukawa, T., Bamba, T., Matsuda, M., Yoshida, T., Inokuma, K., Kim, J., Lee. J.W., Jin, Y.S., Kondo, A., Hasunuma, T. (2023/02) Enhanced production of 3,4-dihydroxybutyrate from xylose by engineered yeast via xylonate re-assimilation under alkaline condition, Biotechnology and Bioengineering, 120(2): 511-523
-
Sakae, K., Nonaka, D., Kishida, M., Hirata, Y., Fujiwara, R., Kondo, A., Noda, S., Tanaka, T. (2023/03) Caffeic acid production from glucose using metabolically engineered Escherichia coli, Enzyme and Microbial Technology, 164, 110193
-
Inokuma, K., Miyamoto, S., Morinaga, K., Kobayashi, Y., Kumokita, R., Bamba, T., Ito, Y., Kondo, A., Hasunuma, T. (2023/04) Direct production of 4-hydroxybenzoic acid from cellulose using cellulase-displaying Pichia pastoris, Biotechnology and Bioengineering, 120(4): 1097-1107
-
Tanaka, K., Shirai, T., Vavricka, CJ., Matsuda, M., Kondo, A., Hasunuma, T. (2023/04) Dark accumulation of downstream glycolytic intermediates initiates robust photosynthesis in cyanobacteria, Plant Physiology, 191(4), 2400-2413
-
Kudo, H., Ono, S., Abe, K., Matsuda, M., Hasunuma, T., Nishizawa, T., Asayama, M., Nishihara, H., Chohnan, S. (2023/4) Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate), Microbial Cell Factories, 22(1): 75
-
Kato, Y., Inabe, K., Haraguchi, Y., Shimizu, T., Kondo, A., Hasunuma, T. (2023/05) L-Lactate treatment by photosynthetic cyanobacteria expressing heterogeneous L-lactate dehydrogenase, Scientific Reports, 13(1): 7249
-
Yoshida, E., Kato, Y., Kanamoto, A., Kondo, A., Hasunuma, T. (2023/05) Metabolomic analysis of the effect of nitrogen on fucoxanthin synthesis by the haptophyte Pavlova gyrans. Algal Research, 72, 103144
-
Yamaguchi, A., Maeshige, N., Yan, J., Ma, X., Uemura, M., Matsuda, M., Nishimura, Y., Hasunuma, T., Kondo, H., Fujino, H., Yuan, ZM. (2023/5) Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages, Frontiers in Immunology, section Inflammation, 14: 1099799
-
Arai, T.*, Wada, M., Nishiguchi, H., Takimura, Y., Ishii, J.* (2023/5) Inducer-free recombinant protein production in Trichoderma reesei: Secretory production of endogenous enzymes and heterologous nanobodies using glucose as the sole carbon source. Microbial Cell Factories, 22(1): 103
-
Kawaguchi, H., Masuo, S., Wakai, K., Takaya, N., Hasunuma, T., Kaneko, T., Okada, S., Sazuka, T., Ogino, C., Kondo, A. (2023/5) Metabolic engineering for 4-aminophenylalanine production from lignocellulosic biomass by recombinant Escherichia coli, RSC Sustainability, 1(4): 1043-1054
-
Haraguchi, Y., Kato, Y., Inabe, K., Kondo, A., Hasunuma, T., Shimizu, T. (2023/06) Circular cell culture for sustainable food production using recombinant lactate-assimilating cyanobacteria that supplies pyruvate and amino acids, Archives of Microbiology, 205(7), 266
-
Inokuma,K., Sasaki,D., Kurata,K., Ichikawa,M., Otsuka,Y., Kondo,A. (2023/7) Sulfated and non-sulfated chondroitin affect the composition and metabolism of human colonic microbiota simulated in an in vitro fermentation system, Scientific Reports, 13(1):12313
-
Doke, M., Kishida, M., Hirata, Y., Nakano, M., Horita, M., Nonaka, D., Mori, Y., Fujiwara, R., Kondo, A., Noda, S., Tanaka, T.*(2023/07) Hydroxybenzoic acid production using metabolically engineered Corynebacterium glutamicum, Synthetic Biology and Engineering, 1(2),10012
-
Sasaki, D., Sasaki, K., Abe, A., Ozaki, M., Kondo, A. (2023/7) Effects of partially hydrolyzed guar gums of different molecular weights on a human intestinal invitro fermentation model, Journal of Bioscience and Bioengineering, 136(1), 67-73
- Hanh, DD., Elkasaby, T., Kawaguchi, H., Tsuge, Y., Ogino, C., Kondo, A. (2023/07) Enhanced production of itaconic acid from enzymatic hydrolysate of lignocellulosic biomass by recombinant Corynebacterium glutamicum, Journal of Bioscience and Bioengineering, 136(1): 7-12
- Y, Tamaru., S, Nakanishi., K, Tanaka., M, Umetsu., H, Nakazawa., A, Sugiyama., T, Ito., N, Shimokawa., M, Takagi., (2023/08) Recent research advances on non-linear phenomena in various biosystems. Journal of Bioscience Bioengineering, 136, 75-86.
-
Elkasaby, T., Hanh, DD., Kawaguchi, H., Kondo, A., Ogino, C. (2023/8) Effect of different metabolic pathways on itaconic acid production in engineered Corynebacterium glutamicum, Journal of Bioscience and Bioengineering, 136(2): 109-116
- Putra, FJN., Kahar, P., Kondo, A., Ogino, C. (2023/08) The bioconversion of lignin derivative aldehydes into high-value aromatic alcohols and lipids via Lipomyces starkeyi, Biochemical Engineering Journal, 200, 109065
-
Mori, A., Hirata, Y., Kishida,M., Mori, Y., Kondo, A., Noda, S., Tanaka,T.* (2023/9) p-Nitrobenzoate production from glucose by utilizing p-aminobenzoate N-oxygenase: AurF, Enzyme and Microbial Technology, 171: 110321
-
Kumokita, R., Yoshida, T., Shirai, T., Kondo, A., Hasunuma, T. (2023/9) Aromatic secondary metabolite production from glycerol was enhanced by amino acid addition in Pichia pastoris , Applied Microbiology and Biotechnology, 107(24): 7391–7401
-
Matsuoka, Y., Fujie, N., Nakano, M., Koshiba, A., Kondo, A., Tanaka, T.* (2023/10) Triacetic acid lactone production using 2-pyrone synthase expressing Yarrowia lipolytica via targeted gene deletion, Journal of Bioscience and Bioengineering, 136(4): 320-326
- Elkasaby, T., Hanh, DD., Kawaguchi, H., Toyoshima, M., Kondo, A., Ogino, C. (2023/10) Co-utilization of Maltose and Sodium Acetate via Engineered Corynebacterium glutamicum for Improved Itaconic Acid Production, Biotechnology and Bioprocess Engineering, 28(5): 790-803
-
Uemura, M., Maeshige, N., Yamaguchi, A., Ma, X., Matsuda, M., Nishimura, Y., Hasunuma, T., Inoue, T., Yan, J., Wang, J., Kondo, H., Fujino, H. (2023/10) Electrical stimulation facilitates NADPH production in pentose phosphate pathway and exerts an anti-inflammatory effect in macrophages, Scientific Reports, 13(1): 17819
-
Yatabe, F., Seike, T., Okahashi, N., Ishii, J., Matsuda, F. (2023/10) Improvement of ethanol and 2,3-butanediol production in Saccharomyces cerevisiae by ATP wasting. Microbial Cell Factories, 22(1): 204
-
Sugimura, M., Seike, T., Okahashi, N., Izumi, Y., Bamba, T., Ishii, J., Matsuda F. (2023/11) Improved 2,3-butanediol production rate of metabolically engineered Saccharomyces cerevisiae by deletion of RIM15 and activation of pyruvate consumption pathway. International Journal of Molecular Sciences, 24(22): 16378
-
Morita, K., Takenaka, M., Tomita, K., Ishii, J., Kawaguchi, H., Murakami, D., Amo, H., Fujii, M., Maruyama, T., Matsumoto, T., Nishino, T., Ogino, C. (2023/11) Nanoscopic lignin mapping on cellulose nanofibers via scanning transmission electron microscopy and atomic force microscopy. Cellulose, 30: 11357–11367
-
Bamba, T., Hori, Y., Umebayashi, K., Soh, C., Hakozaki, T., Toyama, K., Osumi, M., Kondo, A., Hasunuma, T. (2023/11) Comprehensive metabolic profiling of Geotrichum candidum and comparison with Saccharomyces cerevisiae, Journal of Bioscience and Bioengineering, 137(1): 9-15
- Zhao, S., Zhang, T., Hasunuma, T., Kondo, A., Zhao, XQ., Feng, JX. (2023/11) Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma reesei, Critical Reviews in Biotechnology, 1-21
-
Sugimoto, K., Hori, K., Ishikawa, M., Ito, H., Kamachi, T., Tanaka, K., Chen, Y., Nakanishi, S. (2023/11) Electrochemical Monitoring of Metabolic Activity of Methane/Methanol Conversing Methylococcus Capsulatus (Bath) Cells Based on Extracellular Electron Transfer, Electrochemistry, 1344-3542
-
Putra, F.J.N., Kahar, P., Kondo, A., Ogino, C. (2023/11). The bioconversion of lignin derivative aldehydes into high-value aromatic alcohols and lipids via Lipomyces starkeyi, Biochemical Engineering Journal, 200, 109065
-
Uy, Abigail Loren Tung., Yamamoto, A., Matsuda, M., Hasunuma, T., Demura, T., Ohtani, M. (2023/12) The carbon flow shifts from primary to secondary metabolism during xylem vessel cell differentiation in Arabidopsis thaliana, Plant and Cell Physiology, 64, 1563-1575
-
Hidese, R., Ohbayashi, R., Kato, Y., Matsuda, M., Tanaka, K., Imamura, S., Ashida, H., Kondo, A., Hasunuma, T. (2023/12) ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels, Communications Biology, 6, 1285
- Pangestu, R., Kahar, P., Ogino, C., Kondo, A. (2023/12) Comparative responses of flocculating and nonflocculating yeasts to cell density and chemical stress in lactic acid fermentation, Yeast 3917
-
Narutaki, A., Kahar, P., Shimadzu, S., Maeda, S., Furuya, T., Ishizaki, K., Fukaki, H., Ogino, C., Kondo, Y. (2023/12) Sucrose signaling contributes to the maintenance of vascular cambium by inhibiting cell differentiation, Plant and Cell Physiology, S, 64(12), 1511–1522
-
Wijaya, H., Kahar, P., Sasaki, K., Rahmani, N., Hermiati, E., Yopi, Ogino, C., Prasetya, B., Simarmata, R., Christita, M., Kondo, A. (2023/12) Saccharification of pretreated empty bunch by concentrated xylanase and assisted by cellulase, AIP Conference Proceedings, 2972(1): 040001
総説・解説
-
近藤昭彦, 特集 CO2から有用物質を生産し低炭素社会実現へ:「バイオものづくり」が導く低炭素社会, JST news, 1, 4-5 (2023/01)
-
蓮沼誠久, 特集 CO2から有用物質を生産し低炭素社会実現へ:AIと代謝工学を組み合わせ生産株開発を加速, JST news, 1, 10-11 (2023/01)
-
近藤昭彦, 生物工学賞「バイオ物質生産に資するスマートセル創出に向けた革新的アプローチ」, 生物工学会誌, 101(1), 2-14 (2023/01)
-
田中謙也, 蓮沼誠久,「光合成が始まる瞬間の代謝機構」, 光合成研究,33,23-33 (2023/04)
-
高相昊, 田口精一, メンブレンベシクル創発の新原理~バイオプラスチック合成が“引き金”~, 化学と生物, 61(5), 217-219 (2023/05)
-
伊藤洋一郎, 石井純, 近藤昭彦, ピキア酵母の多重遺伝子欠損による難分泌性抗体タンパク質の生産性向上, Bioscience & Industry, 81(3), 234-236 (2023/05)
-
荻野千秋, 松田史生, 特集 バイオマスは日本のどこにある? -特集によせて-, 生物工学会誌, 101(5), 216 (2023/05)
-
荻野千秋, 特集 バイオマスは日本のどこにある? -海外・国内での農業廃棄物系バイオマスによるコンビナート構想-, 生物工学会誌, 101(5), 234-237 (2023/05)
著書
-
蓮沼誠久, I編 生物資源利用の基礎:3. 物理・化学的変換技術の理論「3.3 バイオリファイナリー」, 119-128,
Ⅱ編 生物資源の応用技術:2. エネルギー利用技術「2.4 バイオリファイナリー産物」, 229-237, 農業・食料生産分野におけるバイオマス利用工学 -循環型社会のための生物資源利用-, コロナ社 (2023/04) -
蓮沼誠久(監修), はじめに, 微生物を活用した有用物質の製造技術, シーエムシー出版 (2023/05)
-
戸谷吉博, 松田史生, 石井純, 原清敬, 第1章 バイオものづくりに資する微生物と育種技術 -4. 光をエネルギー源にして利用する有用物質生産大腸菌の開発-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 24-30 (2023/05)
-
西田敬二, 第2章 高度なバイオものづくり用微生物を開発するための要素技術 -2. 微生物でのゲノム編集の有用性-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 48-52 (2023/05)
-
蓮沼誠久, 第2章 高度なバイオものづくり用微生物を開発するための要素技術 -6. 微生物物質生産に資するオミクス技術-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 73-80 (2023/05)
-
近藤昭彦, 竹中武藏, 第2章 高度なバイオものづくり用微生物を開発するための要素技術 -7. バイオエコノミーの開拓者:バイオファウンドリ-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 81-87 (2023/05)
-
白井智量, 森裕太郎, 第3章 化成品原料の生産 -4. 代謝設計・酵素設計によるゴム原料の微生物生産-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 111-116 (2023/05)
-
秀瀬涼太, 蓮沼誠久, 第5章 CO2からの有用物質生産 -2. 水素酸化細菌によるCO2吸収-, 微生物を活用した有用物質の製造技術, シーエムシー出版, 170-179 (2023/05)
-
近藤昭彦, 佐々木大介, 第2章 精密栄養学を支える基盤技術 -6. 食の評価(in vitro腸内細菌培養システム), 実験医学 増刊号 「精密栄養学」, 羊土社, 41(10), 75-80 (2023/06)
-
川口 秀夫, Prihardi Kahar, 荻野 千秋, 草本バイオマスを原料としたバイオリファイナリー利用, 草本バイオマスの増産と利用, アグリバイオ, 510-514 (2023/06)
-
加藤悠一,田中謙也,蓮沼誠久,第5章 第14節 シアノバクテリアを利用した二酸化炭素からの有用物質生産技術,CO2の有効利用技術の開発,技術情報協会,293-300 (2023/7)
-
新谷知也, 佐々木大介, 動物実験代替法とNew Approach Methodologiesの開発・利用動向, CMC出版, 第VII編第2章, p.264-272 (2023/09)
-
Kahar, P., Guirimand, G., Hasunuma, T., Ethanol Production by Recombinant CBP Yeasts. In: Bisaria, V. (eds) Handbook of Biorefinery Research and Technology. , Springer, 1-22, (2023/10)
-
Kahar, P., Guirimand, G., Hasunuma, T., Ethanol Production by Recombinant CBP Yeasts, Handbook of Biorefinery Research and Technology, Springer, 1-22 (2023/10)
-
蓮沼誠久, 14-6 スマートセルインダストリー, テクノロジー・ロードマップ 2024-2033 全産業編, 日経BP (2023/11)