発表論文

TOP 発表論文 Papers 2024

研究成果

Papers 2024

  1. Yanagibashi, S., Bamba, T., Kirisako, T., Kondo, A., Hasunuma, T. (2024/01) Beneficial effect of optimizing the expression balance of the mevalonate pathway introduced into the mitochondria on terpenoid production in Saccharomyces cerevisiae, Journal of Bioscience and Bioengineering, 137(1): 16-23

  2. Elkasaby, T., Hanh, DD., Kahar, P., Kawaguchi, H., Sazuka, T., Kondo, A., Ogino, C. (2024/01) Utilization of sweet sorghum juice as a carbon source for enhancement of itaconic acid production in engineered Corynebacterium glutamicum, Enzyme and Microbial Technology, 172: 110345

  3. Noda, S., Fujiwara, R., Mori, Y., Dainin, M., Shirai, T., Kondo, A. (2024/01) Styrene Production in Genetically Engineered Escherichia coli in a Two-Phase Culture, BioTech, 13(1), 2

  4. Yanagibashi, S., Bamba, T., Kirisako, T., Kondo, A., Hasunuma, T. (2024/01) The potency of mitochondria enlargement for mitochondria-mediated terpenoid production in yeast, Applied Microbiology and Biotechnology, 108: 110

  5. Elkasaby, T., Hanh, D.D., Kahar, P., Kawaguchi, H., Sazuka, T., Kondo, A., Ogino, C. (2024/01) Utilization of sweet sorghum juice as a carbon source for enhancement of itaconic acid production in engineered Corynebacterium glutamicum, Enzyme and Microbial Technology, 172, 110345

  6. Yuan, B., Wang, WB., Wang, XQ., Liu, CG., Hasunuma, T., Kondo, A., Zhao, XQ. (2024/02) The chromatin remodeler Ino80 regulates yeast stress tolerance and cell metabolism through modulating nitrogen catabolite repression, International Journal of Biological Macromolecules, 258, 129041

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  7. Kumokita, R., Bamba, T., Yasueda, H., Tsukida, A., Nakagawa, K., Kitagawa, T., Yoshioka, T., Matsuyama, H., Yamamoto, Y., Maruyama, S., Hayashi, T., Kondo, A., Hasunuma,T. (2024/02) High-level phenol bioproduction by engineered Pichia pastoris in glycerol fed-batch fermentation using an efficient pertraction system, Bioresource Technology, 393, 130144

  8. Tanaka, K., Bamba, T., Kondo, A., Hasunuma, T. (2024/02) Metabolomics-based development of bioproduction processes toward industrial-scale production. Current Opinion in Biotechnology, 85, 103057

  9. Sasaki, K., Takeshima, Y., Fujino, A., Yamashita, J., Kimoto, A., Sasaki, D., Kondo, A., Akashi, M., Okumura, R. (2024/02) Construction of a versatile in vitro cultivation screening platform using human oral microbiota, Environmental Microbiology Reports, 16(2): e13243

  10. Kato, Y., Hidese, R., Matsuda, M., Ohbayashi, R., Ashida, H., Kondo, A., Hasunuma, T. (2024/02) Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria, Communications Biology, 7, 233

  11. Matsuyama, C., Seike, T., Okahashi, N., Niide, T., Hara, KY., Hirono-Hara, Y., Ishii, J., Shimizu, H., Toya, Y., Matsuda, F. (2024/03) Metabolome analysis of metabolic burden in Escherichia coli caused by overexpression of green fluorescent protein and delta-rhodopsin, Journal of Bioscience and Bioengineering, 137(3), 187-194

  12. Koh, S., Furutate, S., Imai, Y., Kanda, T., Tanaka, S., Tominaga, Y., Sato, S., Taguchi, S. (2024/04) Microbial platform for tailor-made production of a biodegradable polylactide modifier: Ultrahigh-molecular-weight lactate-based polyester LAHB, ACS Sustainable Chem. Eng., 12, 6145-6156

  13. Pangestu, R., Kahar, P., Ogino, C., Kondo, A. (2024/04) Comparative responses of flocculating and nonflocculating yeasts to cell density and chemical stress in lactic acid fermentation, Yeast, 41, 192–206

  14. Asama, R., Liu, C.J.S., Tominaga, M., Cheng, Y-R., Nakamura, Y., Kondo, A., Wang, H-Y., Ishii, J. (2024/04) Droplet-based microfluidic platform for detecting agonistic peptides that are self-secreted by yeast expressing a G-protein-coupled receptor, Microbial Cell Factories, 23, 104

  15. Imai, Y., Tominaga, Y., Tanaka, S., Yoshida, M., Furutate, S., Sato, S., Koh, S., Taguchi, S. (2024/05) Modification of poly(lactate) via polymer blending with microbially produced poly[(R)-lactate-co-(R)-3-hydroxybutyrate] copolymers, International Journal of Biological Macromolecules, 266, 130990

  16. Yoshida, E., Kato, Y., Kanamoto, A., Kondo, A., Hasunuma, T. (2024/05) Mixotrophic culture enhances fucoxanthin production in the haptophyte Pavlova gyrans, Applied Microbiology and Biotechnology, 108, 352

  17. Shintani, T., Sasaki, D., Matsuki, Y., Kondo, A, (2024/06) In vitro human colon microbiota culture model for drug research, Medicine in Drug Discovery, 22: 100184

  18. Takenaka, M., Kamasaka, K., Daryong, K., Tsuchikane, K., Miyazawa, S., Fujihana, S., Hori, Y., Vavricka, CJ., Hosoyama, A., Kawasaki, H., Shirai, T., Araki, M., Nakagawa, A., Minami, H., Kondo, A., Hasunuma, T. (2024/06) Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis, Microbial cell factories, 23, 178

  19. Bamba, T., Aoki, R., Hori, Y., Ishikawa, S., Yoshida, KI., Taoka, N., Kobayashi, S., Yasueda, H., Kondo, A., Hasunuma, T. (2024/06) High-throughput evaluation of hemolytic activity through precise measurement of colony and hemolytic zone sizes of engineered Bacillus subtilis on blood agar, Biology Methods & Protocols, 9(1):bpae044

  20. Mori, H., Matsui, M., Bamba, T., Hori, Y., Kitamura, S., Toya, Y., Hidese, R., Yasueda, H., Hasunuma, T., Shimizu, H., Taoka, N., Kobayashi, S. (2024/07) Engineering Escherichia coli for efficient glutathione production, Metabolic engineering, 84, 180-190

  21. Asama, R., Tominaga, M., Ito, S., Ito, Y., Takemura, K., Sakuraba, S., Katsurada, K., Fukuda, N., Kondo, A., Ishii, J.(2024/07) Screening of protein-based inhibitors for the intracellular domain of epidermal growth factor receptor by directed evolution using the yeast Gγ recruitment system, Journal of Bioscience and Bioengineering, 138(5), 375-381

  22. Koh, S., Endo, R., Kahar, P., Mori, Y., Ogino, C., Tanaka, S., Tanaka, S., Imai, Y., Taguchi, S. (2024/08) Complete sequence randomness of lactate-based copolymers (LAHBs) with varied lactate monomer fractions employing a series of propionyl-CoA transferases., International Journal of Biological Macromolecules, 274, 133055

  23. Putra, F.J.N., Kahar, P., Kondo, A., Ogino, C. (2024/08) Production of lignin monomeric alcohols and lipids from oil palm empty fruit bunch by a combination of alkaline nitrobenzene depolymerization and Lipomyces starkeyi bioconversion, Biochemical Engineering Journal, 208, 109347

  24. Noda, S., Mori, Y., Ogawa, Y., Fujiwara, R., Dainin, M., Shirai, T., Kondo, A. (2024/08) Metabolic and enzymatic engineering approach for the production of 2-phenylethanol in engineered Escherichia coli, Bioresource Technology, 406, 130927

  25. Inokuma, K., Toyohara, K., Hamada, T., Kondo, A., Hasunuma, T. (2024/08) One-pot synthesis of cellobiose from sucrose using sucrose phosphorylase and cellobiose phosphorylase co-displaying Pichia pastoris as a reusable whole-cell biocatalyst, Scientific Reports, 14: 18540

  26. Zain, N.A.A., Kahar, P., Sudesh, K., Ogino, C., Kondo, A. (2024/08) Production of single cell oil by Lipomyces starkeyi from waste plant oil generated by the palm oil mill industry, Journal of Bioscience and Bioengineering, 138(2), 153-162

  27. Apriliana, P., Kahar, P., Kashiwagi, N., Kondo, A., Ogino, C. (2024/08) Editing Streptomyces genome using target AID system fused with UGI-degradation tag, Engineering in Life Sciences, e2400005

  28. Chu, S., Haraguchi, Y., Asahi, T., Kato, Y., Kondo, A., Hasunuma, T., Shimizu, T. (2024/08) A serum-free culture medium production system by co-culture combining growth factor-secreting cells and l-lactate-assimilating cyanobacteria for sustainable cultured meat production, Scientific Reports, 14: 19578

  29. Nonaka, D., Hirata, Y., Kishida,M., Mori, A., Fujiwara, R., Kondo, A., Mori, Y., Noda, S., Tanaka,T.(2024/08) Parallel metabolic pathway engineering for aerobic 1,2-propanediol production in Escherichia coli, Biotechnology Journal, 19(8), e2400210

  30. Koh, S., Saito, Y., Kudo, H., Taguchi, S., Kumagai, A., Mizuno, M., Samejima, M., Amano, Y. (2024/09) Synthesis of a natural core substrate with lignin-xylan cross-linkage for unveiling the productive kinetic parameters of glucuronoyl esterase, Biochemical Biophysical Research Communications, 734, 150642

  31. Koh, S., Sato, M., Matsusaki, H., Taguchi, S. (2024/09) The Discovery of Membrane Vesicle Biogenesis in the Polyhydroxybutyrate-non- producing Mutant Strain of Cupriavidus necator H16, Microbes and Environments, 39(3), ME24007

  32. Tanaka, K., Kondo, A., Hasunuma, T. (2024/09) Minimized dark consumption of Calvin cycle intermediates facilitates the initiation of photosynthesis in Synechocystis sp. PCC 6803, Plant Cell Physiology, pcae102

  33. Tsuji, A., Inabe, K., Hidese, R., Kato, Y., Domingues, L., Kondo, A., Hasunuma, T. (2024/10) Pioneering precision in markerless strain development for Synechococcus sp. PCC 7002, Microbial Cell Factories, 23,268

  34. Haraguchi, Y., Kato, Y., Tsuji, A., Hasunuma, T., Shimizu, T. (2024/10) Recombinant lactate-assimilating cyanobacteria reduce high-concentration culture-associated cytotoxicity in mammalian cells, Archives of Microbiology, 206(11),425

  35. Putra, F.J.N., Kahar, P., Kondo, A., Ogino, C. (2024/10). Adaptive laboratory evolution of Lipomyces starkeyi for high production of lignin derivative alcohol and lipids with comparative untargeted metabolomics-based analysis. Microbial Cell Factory, 23, 270.

  36. Kahar, P. (2024/10). Insights in Synthetic Bioengineering and Aspects of Creating a New Biotechnology. SynBio, 2(4), 344-348.

  37. Rachmadona, N., Kahar, P., Juanssilfero, A.B. et al. (2024/10). Evaluation of lipid production efficiency using palm oil mill effluent as a carbon source by Lipomyces starkeyi. Biomass Conversion and Biorefinery.

  38. Koshiba, A., Nakano, M., Hirata, Y., Konishi, R., Matsuoka, Y., Miwa, Y., Mori, A., Kondo, A., Tanaka,T.(2024/11) Enhanced production of isobutyl and isoamyl Acetate using Yarrowia lipolytica, Biotechnology Progress, 40(6), e3499

  39. Postiaux, A., Putra, F.J.N., Kahar, P., Richel, A., Ogino, C. (2024/11). Maleic Acid-Butanol Pretreatment to Enhance Cellulose Accessibility for Enzymatic Hydrolysis and Ethanol Production from Oil Palm Empty Fruit Bunch. ACS Environmental Au, 5, 1, 76–85.

  40. Mitsui, R., Kondo, A., Shirai, T. (2024/12) Production of (R)-citramalate by engineered Saccharomyces cerevisiae, Metabolic Engineering Communications, 19,

  41. Hasunuma, T., Jin, YS. (2024/12) Editorial overview: Chemical biotechnology paving the way for a sustainable future, Current Opinion in Biotechnology, 90, 103215

  42. Tominaga, M., Shima, Y., Nozaki, K., Ito, Y., Someda, M., Shoya, Y., Hashii, N., Obata, C., Matsumoto-Kitano, M., Suematsu, K., Matsukawa, T., Hosoya, K., Hashiba, N., Kondo, A., Ishii, J. (2024/12) Designing strong inducible synthetic promoters in yeasts Nature Communications, 15, 10653

  43. Bamba, T., Munakata, R., Ushiro, Y., Kumokita, R., Tanaka, S., Hori, Y., Kondo, A., Yazaki, K., Hasunuma, T. (2024/12) De novo production of the bioactive phenylpropanoid artepillin C using membrane-bound prenyltransferase in Komagataella phaffii. ACS Synthetic Biology, 13(12):4040-4049

総説・解説

  1. 森 裕太郎, つなげ，電子のタスキ！あげろ，エネルギー準位！, 生物工学会誌, 102(1), 26-26 (2024/01)

  2. 佐々木大介, 新谷知也, 特集；食物繊維を巡る最新の話題, In vitro培養モデルによる食物繊維の腸内細菌叢への影響評価, 食品と開発, インフォーママーケッツジャパン, 59(1) (2024/01)

  3. 高 相昊, 「代謝と材料」両睨みのバイオものづくり, 生物工学会誌, 102(5) (2024/5)

  4. 冨永将大, 近藤昭彦, 石井純, 酵母における遺伝子スイッチ進化工学ワークフローの「ロバスト化」, 生物物理, 64(3), 144-146 (2024/06)

  5. 近藤昭彦, 巻頭言　バイオものづくりによるGXの推進, Bioscience & Industry, 82(4), 366-367 (2024/07)

  6. 蓮沼誠久, 産業と行政　バイオものづくりに資するテンプレート酵素の探索と応用, Bioscience & Industry, 82(4), 432-434 (2024/07)

  7. 蓮沼誠久, ppGppによるラン藻の窒素利用制御, 光アライアンス, 35(9), 18-21 (2024/09)

  8. 高 相昊, 微生物がつくる “エコ” なプラスチック~海洋プラごみ汚染問題への挑戦~, エコひょうご, 112 (秋号), 1-4 (2024/09)

  9. 近藤昭彦, 「バイオものづくり」CO2からバイオプラスチック生産, Kobe University Technology Promotion Club, 99, 3-7 (2024/09)

  10. 田口精一, 世界初、海水中で分解できる“強靭性”と“生分解性”を両立したプラスチックの大量生産に成功（上）, 科学機器, 915, 10-17 (2024/09)

  11. 蓮沼誠久, ppGpp に着目した細胞増殖制御による光合成的芳香族生産, BIO INDUSTRY, 41(10)通巻487号, 1-7 (2024/10)

  12. 田口精一, 世界初、海水中で分解できる“強靭性”と“生分解性”を両立したプラスチックの大量生産に成功（下）, 科学機器, 916, 14-21 (2024/10)

  13. 近藤昭彦, 熱量とハングリー精神, 生物工学会誌, 102（12）, 605 (2024/12)

著書

  1. 蓮沼誠久，第11章 微生物によるカロテノイド高生産とメタボローム解析の応用, カロテノイドの科学 -基礎, 研究の新展開, 生理活性-, シーエムシー出版, 123-131 (2024/03)

  2. Putra, F.J.N., Kahar P, Ogino C, Kondo. A. Advanced Lignin Valorization for Biorefinery Application, Advanced Lignin Technologies [Working Title], IntechOpen (2024/04)

  3. 蓮沼誠久, 第8章 バイオマスの生物化学的変換　５節 代謝と遺伝子工学の利用, バイオマスの科学と技術 -未来を創るエネルギー-, コロナ社, 403-418 (2024/07)

  4. 松尾真紀子, 松本拓郎, 石塚大輔, 吉田彩乃, 城山英明, 蓮沼誠久, 立川雅司, 水無渉, バイオエコノミーの実現に向けたバイオものづくりの推進における課題と政策的検討を⾏う上での必須事項に関するフレームワーク, ワーキングペーパー, No.32 (2024/09)

  5. 蓮沼誠久, 第15章 材料/製造, 5.スマートセル・バイオものづくり, テクノロジー・ロードマップ 2025-2034 全産業編, 日経BP (2024/11)