研究成果
Papers 2020
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Inokuma, K., Kurono, H., den Haan, R., van Zyl, W. H., Hasunuma, T., Kondo, A. (2020/01) Novel strategy for anchorage position control of GPI-attached proteins in the yeast cell wall using different GPI-anchoring domains, Metabolic Engineering, 57, 110-117
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Matsumoto, T., Mori, Y., Tanaka, T., Kondo, A. (2020/01) n-Butylamine production from glucose using a transaminase-mediated synthetic pathway in Escherichia coli, Journal of Bioscience and Bioengineering, 129(1), 99-103
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Vavricka, CJ., Hasunuma, T., Kondo, A. (2020/01) (Review) Dynamic metabolomics for engineering biology: Accelerating learning cycles for bioproduction, Trends in Biotechnology, 38(1), 68-82
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Fujiwara, R., Noda, S., Tanaka, T., Kondo, A. (2020/01) Metabolic engineering of Escherichia coli for shikimate pathway derivative production from glucose–xylose co-substrate, Nature Communications, 11: 279
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Vavricka, CJ., Matsumoto, T., Hiromasa K. (2020/01) Towards improvement of covalent neuraminidase inhibitors with anomeric substitution, Trends in Glycoscience and Glycotechnology, 32(185), E1-E5
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Hidese, R.#, Matsuda, M.#, Osanai, T., Hasunuma, T.*, Kondo, A. (2020/01) Malic enzyme facilitates D-lactate production through increased pyruvate supply during anoxic dark fermentation in Synechocystis sp. PCC 6803, ACS Synthetic Biology, 9, 260-268
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Watanabe, N., Murata, M., Ogawa, T., Vavricka, CJ., Kondo, A., Ogino, C., Araki, M. (2020/02) Exploration and evaluation of machine learning-based models for predicting enzymatic reactions, Journal of Chemical Information and Modeling, 60(3), 1833-1843
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Fukuda, W., Yamori, Y., Hamakawa, M., Osaki, M., Fukuda, M., Hidese, R., Kanesaki, Y., Okamoto-Kainum, A., Kato, S., Fujiwara, S. (2020/02) Genes regulated by branched-chain polyamine in the hyperthermophilic archaeon Thermococcus kodakarensis, Amino Acids, 52, 287-299
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Quayson, E., Amoah, J., Rachmadona, N., Hama, S., Yoshida, A., Kondo, A., Ogino, C. (2020/03) Biodiesel-mediated biodiesel production: A recombinant Fusarium heterosporum lipase-catalyzed transesterification of crude plant oils, Fuel Processing Technology, 199, 106278
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Kobayashi, S., Kawaguchi, H., Shirai, T., Ninomiya, K., Takahashi, K., Kondo, A., Tsuge, Y. (2020/03) Automatic redirection of carbon flux between glycolysis and pentose phosphate pathway using an oxygen-responsive metabolic switch in Corynebacterium glutamicum, ACS Synthetic Biology, 9, 814-826
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Wijaya, H., Sasaki, K., Kahar, P., Quayson, E., Rachmadona, N., Amoah, J., Hama, S., Ogino, C., Kondo, A. (2020/04) Concentration of lipase from Aspergillus oryzae expressing Fusarium heterosporum by nanofiltration to enhance transesterification, Processes, 8(4), 450
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Sasaki, K., Sasaki, D., Inoue, J., Hoshi, N., Maeda, T., Yamada, R., Kondo, A. (2020/05) Bacillus coagulans SANK 70528 suppresses Enterobacteriaceae in the microbiota of ulcerative colitis in vitro and enhances butyrogenesis in healthy microbiota, Applied Microbiology and Biotechnology, 104(9), 3859-3867
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Hatanaka, M., Morita, H., Aoyagi, Y., Sasaki, K., Sasaki, D., Kondo, A., Nakamura, T. (2020/05) Effective bifidogenic growth factors cyclo-Val-Leu and cyclo-Val-Ile produced by Bacillus subtilis C-3102 in the human colonic microbiota model, Scientific Reports, 10, 7591
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Wijaya H., Sasaki, K., Kahar, P., Rahmani, N., Hermiati, E., Yopi, Ogino, C., Prasetya, B., Kondo, A. (2020/05) High enzymatic recovery and purification of xylooligosaccharides from empty fruit bunch via nanofiltration, Processes, 8, 619
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Isozaki, A., Nakagawa, Y., Loo, MH., Shibata, Y., Tanaka, N., Setyaningrum, DL., Park, JW., Shirasaki, Y., Mikami, H., Huang, D., Tsoi, H., Riche, CT., Ota, T., Miwa, H., Kanda, Y., Ito, T., Yamada, K., Iwata, O., Suzuki, K., Ohnuki, S., Ohya, Y., Kato, Y., Hasunuma, T., Matsusaka, S., Yamagishi, M., Yazawa, M., Uemura, S., Nagasawa, K., Watarai, H., Di Carlo, D., Goda, K. (2020/05) Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume biological compartments, Science Advances, 6(22), eaba6712
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Sasaki, K., Sasaki, D., Hannya, A., Tsubota, J., Kondo, A. (2020/05) In vitro human colonic microbiota utilises D-β-hydroxybutyrate to increase butyrogenesis, Scientific Reports, 10, 8516
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Fujikura, U., Ezaki, K., Horiguchi, G., Seo, M., Kanno, Y., Kamiya, Y., Lenhard, M., Tsukaya, H. (2020/06) Suppression of class I compensated cell enlargement by xs2 mutation is mediated by salicylic acid signaling, PLOS Genetics, 16(6): e1008873
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Qu, W., Show, PL., Hasunuma, T., Ho, SH. (2020/06) Optimizing real swine wastewater treatment efficiency and carbohydrate productivity of newly microalga Chlamydomonas sp. QWY37 used for cell-displayed bioethanol production, Bioresource Technology, 305, 123072
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Iijima, H., Watanabe, A., Sukigara, H., Shirai, T., Kondo, A., Osanai, T. (2020/06) Simultaneous increases in the levels of compatible solutes by cost‐effective cultivation of Synechocystis sp. PCC 6803, Biotechnology and Bioengineering, 117(6), 1649-1660
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Satowa, D., Fujiwara, R., Uchio, S., Nakano, M., Otomo, C., Hirata, T., Matsumoto, T., Noda, S., Tanaka, T., Kondo, A. (2020/07) Metabolic engineering of E. coli for improving mevalonate production to promote NADPH regeneration and enhance acetyl-CoA supply, Biotechnology and Bioengineeering, 117(7), 2153-2164
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Nitta, N., Iino, T., Isozaki, A., Yamagishi, M., Kitahama, Y., Sakuma, S., Suzuki, Y., Tezuka, H., Oikawa, M., Arai, F., Asai, T., Deng, D., Fukuzawa, H., Hase, M., Hasunuma, T., Hayakawa, T., Hiraki, K., Hiramatsu, K., Hoshino, Y., Inaba, M., Inoue, Y., Ito, T., Kajikawa, M., Karakawa, H., Kasai, Y., Kato, Y., Kobayashi, H., Lei, C., Matsusaka, S., Mikami, H., Nakagawa, A., Numata, K., Ota, T., Sekiya, T., Shiba, K., Shirasaki, Y., Suzuki, N., Tanaka, S., Ueno, S., Watarai, H., Yamano, T., Yazawa, M., Yonamine, Y., Di Carlo, D., Hosokawa, Y., Uemura, S., Sugimura, T., Ozeki, Y., Goda, K. (2020/07) Raman image-activated cell sorting, Nature Communications, 11, 3452
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Sakata, R,C., Ishiguro, S., Mori, H., Tanaka, M., Tastuno, K., Ueda, H., Yamamoto, S., Seki, M., Masuyama, N., Nishida, N., Nishimasu, H., Arakawa, K., Kondo, A., Nureki, O., Tomita, M., Aburatani, H., Yachie, N. (2020/07) Base editors for simultaneous introduction of C-to-T and A-to-G mutations, Nature Biotechnology, 38(7), 865-869
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Narutaki, S., Lee, I., Sugawara, Y., Akada, K., Kondo, A. (2020/07) Case study on the environmental monitoring for biological manufacturing using Time-lapse Shadow Image Analysis, Biologicals, 66, 1-8
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Murai, K., Sasaki, D., Kobayashi, S., Yamaguchi, A., Uchikura, H., Shirai, T., Sasaki, K., Kondo, A., Tsuge, Y. (2020/07) Optimal ratio of carbon flux between glycolysis and the pentose phosphate pathway for amino acid accumulation in Corynebacterium glutamicum, ACS Synthetic Biology, 9(7), 1615-1622
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Yoshida, N., Yamashita, T., Kishino, S., Watanabe, H., Sasaki, K., Sasaki, D., Tabata, T., Sugiyama, Y., Kitamura, N., Saito, Y., Emoto, T., Hayashi, T., Takahashi, T., Shinohara, M., Osawa, R., Kondo, A., Yamada, T., Ogawa, J., Hirata, K. (2020/08) A possible beneficial effect of Bacteroides on faecal lipopolysaccharide activity and cardiovascular diseases, Scientific Reports, 10(1), 13009
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Kawaguchi, H., Sazuka, T., Kondo, A. (2020/08) Complete and draft genome sequences of amino acid-producing Corynebacterium glutamicum strains ATCC 21799 and ATCC 31831 and their genomic islands, Microbiology Resource Announcements, 9(32), e00430-20
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Sato, N., Kishida, M., Nakano, M., Hirata, Y., Tanaka T*. (2020/09) Metabolic engineering of shikimic acid-producing Corynebacterium glutamicum from glucose and cellobiose retaining its phosphotransferase system function and pyruvate kinase activities, Frontiers in Bioengineering and Biotechnology, 8, 569406
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Zhang, S., Wakai, S., Sasakura, N., Tsutsumi, H., Hata, Y., Ogino, C., Kondo, A. (2020/09) Pyruvate metabolism redirection for biological production of commodity chemicals in aerobic fungus Aspergillus oryzae, Metabolic Engineering, 61, 225-237
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Nishimura, Y., Ezawa, R., Morita, K., Nakayama, M., Ishii, J., Sasaki, R., Ogino, C., Kondo, A. (2020/09) In vivo evaluation of the ZHER2-BNC/LP carrier encapsulating an anticancer drug and a radiosensitizer, ACS Applied Bio Materials, 3(11), 7743-7751
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Sasaki, D., Sasaki, K., Kondo, A. (2020/10) Glycosidic linkage structures influence dietary fiber fermentability and propionate production by human colonic microbiota in vitro, Biotechnology Journal, 15(10), 1900523 (10月号表紙採用)
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Oba, S., Sunagawa, T., Tanihiro, R., Awashima, K., Sugiyama, H., Odani, T., Nakamura, Y., Kondo, A., Sasaki, D., Sasaki, K. (2020/10) Prebiotic effects of yeast mannan, which selectively promotes Bacteroides thetaiotaomicron and Bacteroides ovatus in a human colonic microbiota model, Scientific Reports, 10(1), 17351
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Quayson, E., Amoah, J., Rachmadona, N., Morita, K., Darkwah, L., Hama, S., Yoshida, A., Kondo, A., Ogino, C. (2020/11) Valorization of palm biomass waste into carbon matrices for the immobilization of recombinant Fusarium heterosporum lipase towards palm biodiesel synthesis, Biomass and Bioenergy, 142, 105768
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Uunziker, J., Nishida, K., Kondo, A., Kishimoto, S., Ariizumi, T., Ezura, H. (2020/11) Multiple gene substitution by Target-AID base-editing technology in tomato, Scientific Reports, 10(1), 20471
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Cunha, JT., Romani, A., Inokuma, K., Johansson, B., Hasunuma, T., Kondo, A., Domingues, L. (2020/12) Consolidated bioprocessing of corn cob-derived hemicellulose: engineered industrial Saccharomyces cerevisiae as efficient whole cell biocatalysts, Biotechnology for Biofuel, 13(1), 1-15
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Quayson, E., Amoah, J., Hama, S., Kondo, A., Ogino, C. (2020/12) Immobilized lipases for biodiesel production: Current and future greening opportunities, Renewable and Sustainable Energy Reviews, 134, 110355
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Ito, Y., Terai, G., Ishigami, M., Hashiba, N., Nakamura, Y., Bamba, T., Kumokita, R., Hasunuma, T., Asai, K., Ishii, J., Kondo, A. (2020/12) Exchange of endogenous and heterogeneous yeast terminators in Pichia pastoris to tune mRNA stability and gene expression, Nucleic Acids Research, 48(22), 13000-13012
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Yamamoto, H., Hayakawa, E., Tsugawa, H., Moriya, Y., Fukusaki, E., Goto, S., Hasunuma, T., Miura, N., Yoshizawa, A,C. (2020/12) Japan Computational Mass Spectrometry Meeting 2020 Activity Report, Journal of Proteome Data and Methods, 2: 2020. 0005
総説・解説
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蓮沼誠久, Christopher J. Vavricka, 荒木通啓, 新たに設計した代謝経路を用いた大腸菌によるアルカロイド高生産, バイオサイエンスとインダストリー, Vol. 78(1), 32-33 (2020/01)
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蓮沼誠久, <巻頭言>スマートセルインダストリーの形成に向けたバイオ×デジタルの技術開発, 化学工学, Vol. 84(2), 51 (2020/02)
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番場崇弘, 湯川貴弘, 蓮沼誠久, 鉄代謝改変酵母による1,2,4-ブタントリオール生産, バイオサイエンスとインダストリー(B&I), vol.78(2), 114-115 (2020/03)
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佐々木建吾, 持続可能・健康社会の構築に向けた複合微生物系の制御, 生物工学会誌, 第98巻, 第3号, 116-122 (2020/03)
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藤原良介, 田中勉, 野田修平, 微生物に糖を目的別に使い分けさせる新技術によるポリマー原料の生産性向上, クリーンエネルギー, vol. 29(5), 20-25 (2020/05)
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藤原良介, 野田修平, 田中勉, 物質生産とエネルギー獲得を独立させるパラレル型代謝工学技術, バイオサイエンスとインダストリー, Vol. 78(4), 316-317 (2020/07)
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佐々木建吾, 星奈美子, 高性能培養装置による潰瘍性大腸炎腸内細菌叢の是正戦略構築, アグリバイオ, Vol.4(10), 92-96 (2020/09)
著書
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蓮沼誠久, 脱石油に向けたCO2資源化技術―化学・生物プロセスを中心に―, 第Ⅲ編 生物プロセス, 第2章 ラン藻によるバイオコハク酸生産, シーエムシー, 247-254 (2020/07)
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佐々木建吾, バイオリファイナリーと分離技術, 3.1 バイオ化合物(バイオエタノール)生産への膜分離技術の適用, 日本液体清澄化技術工業会, 29-34 (2020/07)
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Ishii, M., Wakai, S. (Eds.) Electron-Based Bioscience and Biotechnology, Springer (2020/09)