神戸大学大学院理学研究科化学専攻 松原研究室

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論文

2026

  • “Preparation of Nitrones by Hydrogenation of 2-(2-Nitro-1-phenylethyl)cyclohexanones”

    X. Li, A. Sakamoto, S. Murakami, R. Matsubara, M. Hayashi
    J. Heterocycl. Chem. Synlett, in press. DOI : 10.1055/a-2770-5422

2025

  • Synthesis of Glycosides Containing D-Allose

    A. Ikemoto, D. Huanlin, C. Chi, S. Murakami, R. Matsubara, M. Hayashi
    J. Heterocycl. Chem. 62, 892–898 (2025).DOI: 10.1002/jhet.70037
  • Photocatalytic CO2 reduction to formate using triarylphosphine as reductant

    J. Xu, S. Murakami, T. Harada, W. Xie, T. Yabuta, M. Hayashi, R. Matsubara
    Tetrahedron, 184, 134787 (2025). DOI: 10.1016/j.tet.2025.1347877
  • Multifaceted reactivity of benzimidazoline as an electron donor, a hydride donor, and a catalyst

    T. Harada, S. Murakami, R. Matsubara
    Tetrahedron Chem, 16, 100147 (2025). DOI: 10.1016/j.tchem.2025.100147
  • CO2からのギ酸製造~希少金属を使用しないCO2変換法~
    R. Matsubara
    (Noble Meta-Free CO2 Conversion to Formic Acid)” エネルギー・資源, 46, 562–573 (2025).
  • Carbazol-3-olate photosensitizers enable photocatalytic hydrodefluorination and Birch-type reduction reactions

    H. Kuang, W. Xie, T. Yabuta, M. Fuki, M. Higashi, Y. Kobori, N. Sakai, S. Akimoto, M. Hayashi, R. Matsubara
    Org. Chem. Front. 12, 3626–3635 (2025). DOI: 10.1039/D5QO00056D
  • Enhancing Reaction Efficiency in Photochemical Organic Synthesis by Controlling the Dynamic Effects of Excitons
    H. Mitsunuma, R. Matsubara
    J. Chem. Phys. 162, 100902 (2025). DOI: 10.1063/5.0240938
  • Non-aerobic and One-pot Synthesis of Carbazoles from Cyclohexanones and Arylhydrazines

    K. Miki, R. Matsubara, M. Hayashi
    Synthesis 57, 1599–1606 (2025). DOI: 10.1055/a-2519-9499
  • Facile Synthesis of 2- and 3-Substituted Indoles Using a Catalytic Amount of Pd/C and 1-Octene System

    D. Xu, R. Matsubara, M. Hayashi
    Synthesis 57, 800-811 (2025). DOI: 10.1055/a-2464-6964
  • Regiodivergent Desymmetrization of meso-4,5-Epoxycyclohex-1-ene

    Y. Wang, M. Wakiya, R. Matsubara, M. Hayashi
    J. Org. Chem. 90, 840-845 (2025). DOI: 10.1021/acs.joc.4c02214

2024

  • Triazolium-Catalyzed Metal-Free Photochemical Reduction of CO2 into Formate

    W. Xie, M. Fuki, A. Sukegawa, K. Okunaka, M. Hayashi, Y. Kobori, R. Matsubara
    ACS Sustainable Chem. Eng. 12, 17328-17335 (2024).
    DOI: 10.1021/acssuschemeng.4c07137
  • Synthesis of 2-(Pyridin-2-yl)phenols and 2-(Pyridin-2-yl)anilines

    K. Miki, K. Maeda, R. Matsubara, M. Hayashi
    J. Org. Chem. 89, 5797-5810 (2024). DOI: 10.1021/acs.joc.4c00423

2023

  • Sensitizer-free photochemical regeneration of benzimidazoline organohydride

    R. Matsubara, T. Harada, W. Xie, T. Yabuta, J. Xu, M. Hayashi
    J. Org. Chem. 88, 12276–12288 (2023). DOI: 10.1021/acs.joc.3c00898
  • Recent progress in synthesis and application of furoxan

    M. Abu Yousef, R. Matsubara
    RSC Advances, 13, 5228–5248 (2023). DOI: 10.1039/d3ra00189j
  • One-pot synthesis of 3-substiuted indoles from 2-(2-nitro-1-phenylethyl)cyclohexanone derivatives

    Y. Kuang, K. Maeda, R. Matsubara, M. Hayashi
    J. Org. Chem.88, 5791–5800 (2023). DOI: 10.1021/acs.joc.3c00233.
  • Photophysical and electrochemical properties of 9-naphthyl-3,6-diaminocarbazole derivatives and their application as photosensitizers

    R. Matsubara, H. Kuang, T. Yabuta, W. Xie, M. Hayashi, E. Sakuda
    J. Photochem. Photobiol. 15, 100176 (2023). DOI: 10.1016/j.jpap.2023.100176
  • Metal-free reduction of CO2 to formate using a photochemical organohydride-catalyst recycling strategy

    W. Xie, J. Xu, U. Md Idros, J. Katsuhira, M. Fuki, M. Hayashi, M. Yamanaka, Y. Kobori,, R. Matsubara
    Nat. Chem. 15, 794–802 (2023). DOI: 10.1038/s41557-023-01157-6
  • Cuticular hydrocarbon reception by sensory neurons in basiconic sensilla of the Japanese carpenter ant
    H. Watanabe, S. Ogata, N. Noudomi, K. Tateishi, H. Nishino, R. Matsubara, M. Ozaki, F. Yokohari
    Front. Cell. Neurosci. Sec. Cellular Neurophysiology. 17, 1084803 (2023). DOI: 10.3389/fncel.2023.1084803

2022

  • Diboration of alkynes accelerated by synergistic effects of ruthenium complexes and phenoxides

    S. Murakami, R. Matsubara, M. Hayashi
    Eur. J. Org. Chem. 15, e202200905 (2022). DOI: 10.1002/ejoc.202200905
  • Chemical identification of an active component and putative neural mechanism for repellent effect of a native ant’s odor on invasive species
    T. Uebi, T. Sakita, R. Ikeda, K. Sakanishi, T. Tsutsumi, Z. Zhang, H. Ma, R. Matsubara, S. Matsuyama, S. Nakajima, R.-N. Huang, S. Habe, A. Hefetz, M. Ozaki
    Front. Physiol. 13, 844084 (2022). DOI: 10.3389/fphys.2022.844084
  • Direct arylation of furoxan using potassium aryltrifluoroborates

    C. Dong, M. Hayashi, R. Matsubara
    Heterocycles. 104, 1770–1781 (2022). DOI: 10.3987/com-22-14720

2021

  • Furoxan incorporation into C–H bonds enabling nitrogen-containing functional group installation into the same

    C. Dong, X. Zhao, Y. Katsuragi, H. Kim, M. Hayashi, R. Matsubara
    J. Org. Chem. 86, 15807–15817 (2021). DOI: 10.1021/acs.joc.1c01950
  • Borylfuroxans : Synthesis and applications

    W. Xie, M. Hayashi, R. Matsubara
    Org. Lett. 23, 4317–4321 (2021). DOI: 10.1021/acs.orglett.1c01250
  • Regiodivergent Desymmetrization Reaction of meso-Azabicycloheptene Providing Two Enantioenriched Structural Isomers

    Yuxin Zheng, Yanze Huang, Peng Gao, Hongyan Liu, Suguru Murakami, Ryosuke Matsubara, and Masahiko Hayashi
    Org. Lett. 23, 2411-2414 (2021). DOI: 10.1021/acs.orglett.1c00036
  • Synthesis of Substituted Anilines from Cyclohexanones Using Pd/C−Ethylene System and Its Application to Indole Synthesis

    Katsumi Maeda, Ryosuke Matsubara, and Masahiko Hayashi
    Org. Lett. 23, 1530-1534 (2021). DOI: 10.1021/acs.orglett.0c04056
  • Photocatalytic Reductive C−O Bond Cleavage of Alkyl Aryl Ethers by Using Carbazole Catalysts with Cesium Carbonate

    Tatsushi Yabuta, Masahiko Hayashi, and Ryosuke Matsubara
    J. Org. Chem. 86, 2545-2555 (2021). DOI: 10.1021/acs.joc.0c02663

2020

  • Synthesis, structure, and catalytic activity of [Cp∗Ru(η1-ArCN)3]PF6 complexes

    Suguru Murakami, Ryosuke Matsubara, Masahiko Hayashi
    Journal of Organometallic Chemistry 933 (2021) 121653. DOI: 10.1016/j.jorganchem.2020.121653
  • Selective Synthesis of Some Aminosugars via Catalytic Aminohydroxylation of Protected 2,3-Unsaturated D‐Gluco- and D‐Galacto-2-hexenopyranosides

    Ippei Fukuhara, Ryosuke Matsubara, and Masahiko Hayashi
    J. Org. Chem. 85, 9179-9189 (2020). DOI: 10.1021/acs.joc.0c01170
  • Synthesis and synthetic application of chloro- and bromofuroxans

    R. Matsubara, A. Ando, H. Hasebe, H. Kim, T. Tsuneda, M. Hayashi
    J. Org.Chem. 85, 5959-5972 (2020). DOI: 10.1021/acs.joc.0c00326
  • Modular synthesis of carbon-substituted furoxans via radical addition pathway. Useful tool for transformation of aliphatic carboxylic acids based on “build-and-scrap” strategy

    R. Matsubara, H. Kim, T. Sakaguchi, W. Xie, X. Zhao, Y. Nagoshi, C. Wang, M. Tateiwa, A. Ando, M. Hayashi, M. Yamanaka, T. Tsuneda
    Org. Lett. 22, 1182-1187 (2020). DOI: 10.1021/acs.orglett.0c00062

2019

  • 9-Aryl-3-aminocarbazole as an environment- and stimulisensitive fluorogen and applications in lipid droplet imaging

    R. Matsubara, T. Kaiba, A. Nakata, T. Yabuta, M. Hayashi, M. Tsubaki, T. Uchino, E. Chatani
    J. Org. Chem. 84, 5535–5547 (2019). DOI: 10.1021/acs.joc.9b00493
  • Activated carbon-promoted dehydrogenation of hydroquinones to benzoquinones, naphthoquinones, and anthraquinones under molecular oxygen atmosphere

    S. Kim, R. Matsubara, M. Hayashi
    J. Org. Chem. 84, 2997–3003 (2019). DOI: 10.1021/acs.joc.8b02961
  • A fluorescent naphthalenediimide-alkoxyfuroxan photoinduced nitric oxide donor

    C. P. Seymour, A. Nakata, M. Tsubaki, M. Hayashi, R. Matsubara
    Bull. Chem. Soc. Jpn. 92, 162–169 (2019). DOI: 10.1246/bcsj.20180219

2018

  • Photoinduced nitrile formation from O-(arylcarbonyl)oxime: Usage as a photoremovable protective group

    R. Matsubara, U. Md Idros, T. Yabuta, H. Ma, M. Hayashi, K. Eda
    ChemPhotoChem 2, 1012–1016 (2018). DOI: 10.1002/cptc.201800167
  • UVA- and visible light-mediated generation of carbon radicals from organochlorides using non-metal photocatalyst

    R. Matsubara, T. Yabuta, U. Md Idros, M. Hayashi, F. Ema, Y. Kobori, K. Sakata
    J. Org. Chem. 83, 9381–9390 (2018). DOI: 10.1021/acs.joc.8b01306
  • Synthesis of arylamines via non-aerobic dehydrogenation using a palladium/carbon-ethylene system

    Y. Shimomoto, R. Matsubara, M. Hayashi
    Adv. Synth. Catal. 360, 3297–3305 (2018). DOI: 10.1002/adsc.201800504
  • Synthesis of sulfonyloxy furoxans via hydroxyfuroxan ammonium salts

    R. Matsubara, Y. Katsuragi, T. Sakaguchi, S. Eguchi, M. Hayashi, A. Ando
    Tetrahedron 74, 3642–3651 (2018). DOI: 10.1016/j.tet.2018.05.029

2017

  • Inositol hexakis phosphate is the seasonal phosphorus reservoir in the deciduous woody plant (Populus alba L.)
    Y. Kurita, K. Baba, M. Ohnishi, R. Matsubara, K. Kosuge, A. Anegawa, C. Shichijo, K. Ishizaki, Y. Kaneko, M. Hayashi, T. Suzaki, H. Fukaki, T. Mimura
    Plant Cell Physiol. 58, 1477–1485 (2017). DOI: 10.1093/pcp/pcx106
  • Synthesis of cyanofuroxans from 4-nitrofuroxans via C–C bond forming reactions

    R. Matsubara, A. Ando, M. Hayashi
    Tetrahedron Lett. 58, 3337–3340 (2017). DOI: 10.1016/j.tetlet.2017.07.015
  • Photosensitization of fluorofuroxans and its application to the development of visible light-triggered nitric oxide donor

    C. P. Seymour, R. Tohda, M. Tsubaki, M. Hayashi, R. Matsubara
    J.Org.Chem. 86, 9647–9654 (2017). DOI: 10.1021/acs.joc.7b01709
  • Synthesis of Enantiomerically Pure(8S,9S,10R,6Z)-Trihydroxy octadec -6-enoic Acid

    Jogula Srinivas, Yoichi Namito, Ryosuke Matsubara, and Masahiko Hayashi
    J.Org.Chem. 82, 5146–5154 (2017). DOI: 10.1021/acs.joc.7b00376
  • Recent topics on catalytic asymmetric 1,4-addition

    Masahiko Hayashi and Ryosuke Matsubara
    Tetrahedron Lett. 58, 1793-1805 (2017). DOI: 10.1016/j.tetlet.2017.03.044
  • Dehydrogenative Formation of Resorcinol Derivatives Using Pd/C-Ethylene Catalytic System

    Ibrahim Yussif El-Deeb, Tatsuya Funakoshi, Yuya Shimomoto, Ryosuke Matsubara, and Masahiko Hayashi
    J. Org. Chem. 82, 2630-2640 (2017). DOI: 10.1021/acs.joc.6b03037
  • Study on the photo-induced nitric oxide-releasing ability of 4-alkoxy furoxans

    R. Matsubara, S. Takazawa, A. Ando, M. Hayashi, R. Tohda, M. Tsubaki
    Asian J. Org. Chem. 6, 619-626 (2017). DOI: 10.1002/ajoc.201700030
  • Synthesis of alkynyl furoxans. Rare carbon–carbon bond-forming reaction on a furoxan ring

    R. Matsubara, S. Eguchi, A. Ando, M. Hayashi
    Org. Biomol. Chem. 15, 1965-1969 (2017). DOI: 10.1039/c7ob00181a
  • Conversion of Cyclohexanones to Alkyl Aryl Ethers Using a Pd/C–Ethylene System

    Ibrahim Yussif El-Deeb, Miaomiao Tian, Tatsuya Funakoshi, Ryosuke Matsubara and Masahiko Hayashi
    Eur. J. Org. Chem. 409–413 (2017). DOI: 10.1002/ejoc.201601362

2016

  • Selective Synthesis of Partially Protected D-Talopyranosides and D-Gulopyranosides via Catalytic Asymmetric Dihydroxylation: Multiplier Effects of Substrate Control and Catalyst Control

    Namito, Yoichi.; Michigami, Kyosuke.; Nagahashi, Takaaki.; Matsubara, Ryosuke.; Hayashi, Masahiko.
    Org. Lett. 18, 6058—6061 (2016). DOI: 10.1021/acs.orglett.6b03000
  • Photoinduced Charge-Transfer State of 4-Carbazolyl-3-(triluoromethyl)benzoic Acid: Photophysical Property and Application to Reduction of Carbon-Halogen Bonds as a Sensitizer

    R. Matsubara, T. Shimada, Y. Kobori, T. Yabuta, T. Osakai, M. Hayashi
    Chem. Asian J. 11, 2006–2010 (2016). DOI: 10.1002/asia.201600538
  • Fluorofuroxans: Synthesis and Application as Photo-induced Nitric Oxide Donors

    A. Ando, R. Matsubara, S. Takazawa, T. Shimada, M. Hayashi
    Asian J. Org. Chem. 5, 886–890 (2016). DOI: 10.1002/ajoc.201600149
  • Synthesis of Furoxans (1,2,5-oxadiazole 2-oxides) from Styrenes and Nitrosonium Tetrafluoroborate in Non-Acidic Media and Mechanistic Study

    R. Matsubara, A. Ando, Y. Saeki, K. Eda, N. Asada, T. Tsutsumi, Y.-S. Shin, M. Hayashi
    J. Heterocyclic Chem. 53, 1094–1105 (2016). DOI: 10.1002/jhet.2360

2015

  • Concise Synthesis of Asymmetrically 4,5-Disubstituted 9,9-Dimethyl-9H-xanthenes.

    Matsubara, R.; Koide, M.; Shin, Y.-S.; Shimada, T.; Hayashi, M.
    Synthesis, 47, 187―192 (2015). DOI: 10.1055/s-0034-1379368

2014

  • Revisiting the Saito Photochemical Reduction and the Development of a One-Pot Deoxygenation of Alcohols.

    Matsubara, R.; Shin, Y.-S.; Shimada, T.; Hayashi, M.
    Asian J. Org. Chem., 3, 1054―1057 (2014). DOI: 10.1002/ajoc.201402123

2013

  • Synthesis of Furoxans from Styrenes under Basic or Neutral Conditions.

    Matsubara, R.; Saeki, Y.; Li, J.; Eda, K.
    Synthesis., 45, 1524―1528 (2013)
    Highlighted by Synfacts (9, 813 (2013)). DOI: 10.1055/s-0033-1338436
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