Research/Project

Changes of the aging appearance are well known to cause "gray hair", "waviness" and more loss of "firmness" and "elasticity" in the hair, while "blotches," "wrinkles," or "sagging" in the skin.

Therefore, our project aims to develop and commercialize a technology that can improve these aging changes in appearance using cosmetic materials produced with advanced green chemical technology, of which the Graduate School of Science and Technology Innovation has a great deal of experience.

  1. Development of new bioconjugation technology to improve firmness, elasticity, and waviness caused by hair aging
  2. Development of next-generation hair-dyeing technology to improve gray hair using natural coloration technology
  3. Development of "wrinkles" and "sagging" by functional ingredients discovered in black vinegar which is already recognized for its medicinal properties, and also development of technology to improve "sensitive skin" and "atopic dermatitis" induced by environmental pollution

In addition to these new technologies, we are developing more new technologies in a wide range of fields such as container developments, sales strategies, and branding, and we are also trying to create new value through a fusion of the business administration and sciences, including the development of new markets with an entrepreneurial spirit.

Development of new bioconjugation technology to improve firmness, elasticity, and waviness of hair which is caused by aging

Seeds category

life science

Keywords

hair care, hair quality improvement, hair straightening

Research

We have discovered a new ingredient through bioconjugation technology to get bouncy, elastic and wave less hair. We are then researching the mechanism and production technology of this new ingredient on hair.

Effects and Applications

Our new technology has been confirmed to be able to straighten African hair, which is extremely frizzy. This straightening not only takes away the waviness, but also improves the twists of the hair.

Furthermore, its technology has the potential to be applied to hair care products to adjust the desired hair quality or shape, which was not possible before.

Development of next-generation hair-dyeing technology to improve gray hair using natural coloration technology

Seeds category

life science

Keywords

hair coloring, natural color, biochemical reaction

Research

We are developing a new biotechnological hair coloring technology to improve graying of aging hair. This technology is based on a color reaction that occurs in living organisms, and our goal is to create a coloring technology that is safer, easier, and more convenient than existing hair coloring techniques. In addition to this new technology, we are working on SDGs-friendly bio-production of dyes and catalysts, as well as developing containers for hair coloring.

Effects and Applications

Our new technology is expected to be the next generation of hair coloring technology, meeting the six criteria of Feel, Natural, Biodegradable, Sustainability, Animal origin-free, and Cost-effectiveness.

Development of skin care application technology for the novel functional ingredient, FRAGLIDE1

Seeds category

life science

Keywords

FRAGLIDE1, skincare

Research

We have found that the functional ingredient ‘FRAGLIDE1’ in the traditional healthy ingredient, fragrant vinegar, has PPAR-γligand activity or ARE activity. Recently, we discovered that its FRAGLIDE1 has XRE-inactivating activity and also suppresses Artemin and MMP-9 expression. And it is expected to have further functions from the results of RNAseq of FRAGLIDE1 using keratinocytes and fibroblasts. We are working to elucidate its function. FRAGLIDE1 has also been found in Japanese black vinegar, and we are researching to elucidate the synthetic pathway of FRAGLIDE1 with the cooperation of a black vinegar manufacturer.

Effects and Applications

Our goal is to develop new technology by using FRAGLIDE1 to improve not only "wrinkles" and "sagging" but also "sensitive skin" and "atopic dermatitis" induced by air pollution. Black vinegar extract containing FRAGLIDE1 or FRAGLIDE1 itself is expected to have high added value as a cosmetic raw material.