山地 秀樹
1962年12月2日
博士(工学)
教授
生物プロセス工学
化学工学
詳細リンク
| 学歴 | 京都大学大学院工学研究科化学工学専攻修士課程修了
(1987) 京都大学工学部化学工学科卒業 (1985) |
|---|---|
| 職歴 |
神戸大学大学院工学研究科 (2007−2011 准教授，
2011− 教授) 神戸大学工学部 (1996−2004 助手， 2004−2007 助教授) School of Chemical Engineering, University of Birmingham (1999−2000 Honorary Research Fellow) 鐘淵化学工業株式会社 (1987−1996) |
| 教育研究 分野 |
生物化学工学 細胞培養工学 |
| 研究内容 | ○動物・昆虫細胞による有用物質生産プロセスの開発 ○バイオリアクター技術の開発 |
| 主要論文 |
○"Efficient production of Japanese encephalitis virus-like particles by
recombinant lepidopteran insect cells", Appl. Microbiol. Biotechnol., 97(3), 1071-1079 (2013) ○"Production of Japanese encephalitis virus-like particles using the baculovirus-insect cell system", J. Biosci. Bioeng., 114(6), 657-662 (2012) ○"Production of antibody in insect cells", Cell Engineering, 7, 53-76 (2011) ○"Adenovirus vector production by low multiplicity infection of 293 cells", Cytotechnology, 59(3), 153-160 (2009) ○"Production of functional antibody Fab fragment by recombinant insect cells", Biochem. Eng. J., 41(3), 203-209 (2008) ○"Immobilization of Escherichia coli cells using porous support particles coated with cationic polymers", J. Biosci. Bioeng., 104(2), 98-103 (2007) ○"Efficient production of recombinant protein in immobilized insect cell culture using serum-free basal media after baculovirus infection", Biochem. Eng. J., 28(2), 67-72 (2006) ○"Cell cycle analysis of Chinese hamster ovary cells stimulated by phosphatidic acid in serum-free culture", J. Biosci. Bioeng., 98(6), 487-489 (2004) ○"Effects of phosphatidic acid on recombinant protein production by Chinese hamster ovary cells in serum-free culture", Biochem. Eng. J. 10(2), 85-92 (2002) ○"Production of recombinant protein by baculovirus-infected insect cells in immobilized culture using porous biomass support particles", J. Biosci. Bioeng., 89(1), 12-17 (2000) ○"Effects of phospholipids on growth of Chinese hamster ovary cells in serum-free media", J. Biosci. Bioeng., 88(3), 306-309 (1999) ○"Optimal production of recombinant protein by the baculovirus-insect cell system in shake-flask culture with medium replacement", J. Biosci. Bioeng., 87(5), 636-641 (1999) ○"Growth kinetics of animal cells immobilized within porous support particles in a perfusion culture", Appl. Microbiol. Biotechnol., 42(4), 531-535 (1994) ○"Growth and death behaviour of anchorage-independent animal cells immobilized within porous support matrices", Appl. Microbiol. Biotechnol., 37(2), 244-251 (1992) ○"Long-term cultivation of anchorage-independent animal cells immobilized within reticulated biomass support particles in a circulating bed fermentor", Appl. Microbiol. Biotechnol., 34(6), 730-734 (1991) ○"Immobilisation of anchorage-independent animal cells using reticulated polyvinyl formal resin biomass support particles", Appl. Microbiol. Biotechnol., 30(6), 609-613 (1989) |
| 学会活動 | ○化学工学会 (正会員 (1983−)) ○日本生物工学会 (正会員 (1988−)) ○日本動物細胞工学会 (正会員 (2000−)) ○近畿化学協会 (正会員 (2003−)) |
| 受賞等 | ○平成8年度化学工学会賞奨励賞
(多孔性の保持粒子を用いる浮遊性動物細胞の固定化培養に関する研究
(1997)) |
| 社会活動 |