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研究業績

2015年
Eri Chatani, Rintaro Inoue, Hiroshi Imamura, Masaaki Sugiyama, Minoru Kato, Masahide Yamamoto, Koji Nishida, and Toshiji Kanaya
"Early aggregation preceding the nucleation of insulin amyloid fibrils as monitored by small angle X-ray scattering"
Sci. Rep. 5, 15485 (2015)

茶谷 絵理
「プログラムされていないフォールディング−アミロイド線維の形成−」
生化学 87, 292-297 (2015)

井上 倫太郎、茶谷 絵理、金谷 利治
「小角X線散乱によるアミロイド線維形成機構に関する研究」
SPring-8/SACLA利用研究成果集 3, 2011B1996/BL40B2 (2015)

2014年
Eri Chatani, Yutaro Tsuchisaka, Yuki Masuda, Roumiana Tsenkova
"Water molecular system dynamics associated with amyloidogenic nucleation as revealed by real time near infrared spectroscopy and aquaphotomics"
PLoS One., 9, e101997 (2014)

Eri Chatani, Hiroshi Imamura, Naoki Yamamoto, and Minoru Kato
"Stepwise organization of the β-structure identifies key regions essential for the propagation and cytotoxicity of insulin amyloid fibrils"
J. Biol. Chem., 289, 10399-10410 (2014)

2013年
茶谷 絵理,井上 倫太郎,竹中 幹人,西田 幸次,金谷 利治
「超小角X線散乱によるインスリンアミロイド線維の構造解析」
SPring-8/SACLA利用研究成果集1, 2011B1951 (2013)

2012年
Eri Chatani, Hisashi Yagi, Hironobu Naiki, and Yuji Goto
"Polymorphism of β2-microglobulin amyloid fibrils manifested by ultrasonication-enhanced fibril formation in trifluoroethanol"
J. Biol. Chem. 287, 22827-22837 (2012)

茶谷 絵理、小沼 剛、後藤 祐児
「アミロイド線維伸長における中間体構造の捕捉と構造解析」
生物物理 52, 148-149 (2012)

2011年
Tsuyoshi Konuma†, Eri Chatani†, Masanori Yagi, Kazumasa Sakurai, Takahisa Ikegami, Hironobu Naiki, and Yuji Goto (†equally contributed)
"Kinetic intermediates of β2-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis"
J. Mol. Biol. 405, 851-862 (2011)

2010年
Yuichi Yoshimura, Kazumasa Sakurai, Young-Ho Lee, Takahisa Ikegami, Eri Chatani, Hironobu Naiki, and Yuji Goto
"Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy"
Protein Sci. 19, 2347-2355 (2010)

Eri Chatani†, Reina Ohnishi†, Tsuyoshi Konuma, Kazumasa Sakurai, Hironobu Naiki, and Yuji Goto (†equally contributed)
"Pre-steady-state kinetic analysis of amyloid fibrils of β2-microglobulin with tryptophan mutagenesis"
J. Mol. Biol., 400, 1057-1066 (2010)

Tsubasa Yamamoto, Eri Chatani, and Minoru Kato
"FTIR observation of compression recovery of the secondary structure of heat denaturated ribonuclease A in sucrose solution"
J. Phys. Conf. Ser., 215, 012155 (2010)

2009年
Eri Chatani, Young-Ho Lee, Hisashi Yagi, Yuichi Yoshimura, Hironobu Naiki, and Yuji Goto
"Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils"
Proc. Natl. Acad. Sci. USA, 106, 11119-11124 (2009)

Young-Ho Lee, Eri Chatani, Kenji Sasahara, Hironobu Naiki, and Yuji Goto
"A comprehensive model for packing and hydration for amyloid fibrils of β2-microglobulin"
J. Biol. Chem., 284, 2169-2175 (2009)

2008年
Yuji Goto, Hisashi Yagi, Keiichi Yamaguchi, Eri Chatani, and Tadato Ban
"Structure, formation and propagation of amyloid fibrils"
Curr. Pharm. Des., 14, 3205-3218 (2008)

Michiko Sakata†, Eri Chatani†, Atsushi Kameda, Kazumasa Sakurai, Hisonobu Naiki, and Yuji Goto (†equally contributed)
"Kinetic coupling of folding and prolyl isomerisation of β2-microglobulin studied by mutational analysis"
J. Mol. Biol., 382, 1242-1255 (2008)

2007年
Hyun-Jin Kim, Eri Chatani, Yuji Goto, and Seung R. Paik
"Seed-dependent accelerated fibrillation of α-synuclein induced by periodic ultrasonication treatment"
J. Microbiol. Biotechnol., 17, 2027-2032 (2007)

茶谷 絵理, 後藤 祐児
「圧力をもちいたアミロイド線維研究の展開」
高圧力の科学と技術, 17, 42-49 (2007)

2006年
Miho Kihara, Eri Chatani, Kentaro Iwata, Kaori Yamamoto, Takanori Matsuura, Atsushi Nakagawa, Hironobu Naiki, and Yuji Goto
"Conformation of amyloid fibrils of 2-microglobulin probed by tryptophan mutagenesis"
J. Biol. Chem., 281, 31061-31069 (2006)

Eri Chatani, Hironobu Naiki, and Yuji Goto
"Seeding-dependent propagation and maturation of β2-microglobulin amyloid fibrils under high pressure"
J. Mol. Biol., 359, 1086-1096 (2006)

茶谷 絵理, 内木 宏延, 後藤 祐児
「圧力でさぐるアミロイド線維の構造構築原理」
高圧力下の生物科学, pp. 85-92, さんえい出版 (2006)

2005年
Eri Chatani, Michiko Kato, Tomoji Kawai, Hironobu Naiki, and Yuji Goto
"Main-chain dominated amyloid structures demonstrated by the effect of high pressure"
J. Mol. Biol., 352, 941-951 (2005)

Miho Kihara, Eri Chatani, Miyo Sakai, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto
"Seeding-dependent maturation of β2-microglobulin amyloid fibrils at neutral pH"
J. Biol. Chem., 280, 12012-12018 (2005)

Bakthisaran Raman, Eri Chatani, Miho Kihara, Tadato Ban, Miyo Sakai, Kazuhiro Hasegawa, Hironobu Naiki, Ch Mohan Rao, and Yuji Goto
"Critical balance of electrostatic and hydrophobic interactions is required for β2-microglobulin amyloid fibril growth and stability"
Biochemistry, 44, 1288-1299 (2005)

Eri Chatani and Yuji Goto
"Structural stability of amyloid fibrils of β2-microglobulin in comparison with its native fold"
Biochim. Biophys. Acta, 1753, 64-75 (2005)

茶谷 絵理, 後藤 祐児
「アミロイド線維形成機構?裏の世界の構築原理」
実験医学, 23, 2384-2390, 羊土社 (2005)

2004年
Takehiro Narimoto, Kazumasa Sakurai, Azusa Okamoto, Eri Chatani, Masaru Hoshino, Kazuhiro Hasegawa, Hironobu Naiki, and Yuji Goto
"Conformational stability of amyloid fibrils of β2-microglobulin probed by guanidine-hydrochloride-induced unfolding"
FEBS Lett., 576, 313-319 (2004)

Haruko Maeda, Eri Chatani, Tomohiro Koyama, Masataka Sugiura, Hirohisa Izumi, and Rikimaru Hayashi
"Indiscriminate glycosylation of procarboxypeptidase Y expressed in Pichia pastoris"
Carbohydr. Res., 339, 1041-1045 (2004)

茶谷 絵理
「圧力で探求するタンパク質疎水性コア構造: ウシ膵臓リボヌクレアーゼAを例として」
日本農芸化学会誌, 78, 407-409 (2004)

2003年
Tetsuya Kadonosono, Eri Chatani, Rikimaru Hayashi, Hideaki Moriyama, and Tatzuo Ueki
"Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A"
Biochemistry, 42, 10651-10658 (2003)

2002年
Eri Chatani, Rikimaru Hayashi, Claude Balny, and Reinhard Lange
"Comparison of heat- and pressure-induced unfolding of ribonuclease A: the critical role of Phe46 which appears to belong to a new hydrophobic chain-folding initiation site"
Biochemistry, 41, 4567-4574 (2002)

Eri Chatani, Rikimaru Hayashi, Hideaki Moriyama, and Tatzuo Ueki
"Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution"
Protein Sci., 11, 72-81 (2002)

Eri Chatani, Tetsuya Kadonosono, and Rikimaru Hayashi
"The structural basis for functionality and stability of hydrophobic core in RNase A as probed by the application of high pressure"
Advances in High Pressure Bioscience and Biotechnology II, pp. 87-94, Elsevier (2002)

2001年
Eri Chatani, Rikimaru Hayashi, Reinhard Lange, and Clande Balny
"Thermal and pressure stability of Phe46 mutants of ribonuclease A"
Trends in High Pressure Bioscience and Biotechnology, pp. 27-32, Elsevier (2001)

Eri Chatani and Rikimaru Hayashi
"Roles of each amino acid residues composing bovine pancreatic ribonuclease A"
J. Biosci. Bioeng., 92, 98-107 (2001)

2000年
Eri Chatani, Naoki Tanimizu, Hiroshi Ueno, and Rikimaru Hayashi
"Structural and functional changes in bovine pancreatic ribonuclease A by the replacement of Phe120 with other hydrophobic residues"
J. Biochem., 129, 917-922 (2000)

Eri Chatani, Naoki Tanimizu, Hiroshi Ueno, and Rikimaru Hayashi
"Expression of soluble bovine pancreatic ribonuclease A in Pichia pastoris and its purification and characterization"
Biosci. Biotechnol. Biochem., 64, 2437-2444 (2000)