メンバー紹介

准教授田中 勉 Tsutomu Tanaka

経歴

2001/03
東京大学 工学部 応用化学科 卒業
2003/03
東京大学大学院 工学系研究科化学生命工学専攻 博士前期課程 修了
2006/03
東京大学大学院 工学系研究科化学生命工学専攻 博士後期課程 修了 博士(工学)
2006/12
神戸大学 自然科学研究科 分子物質科学専攻 助手
2007/04
神戸大学 自然科学系先端融合研究環重点研究部 助教(改組)
2011/10
神戸大学 大学院工学研究科 応用化学専攻 准教授
2018/07
神戸大学 先端バイオ工学研究センター 兼任

受賞等

  • 2021/10 神戸大学 令和3年度学長表彰(財務貢献者)
  • 2020/10 神戸大学 令和2年度学長表彰(財務貢献者)
  • 2019/10 神戸大学工学部 平成30年度優秀教育賞(応用化学科)
  • 2014/12 酵素工学研究会 酵素工学奨励賞
  • 2014/01 日本農芸化学会 BBB論文賞受賞
  • 2013/09 日本生物工学会 生物工学論文賞
  • 2011/03 平成22年度化学工学会 研究奨励賞

発表論文

  1. Noda, S*., Mori, Y., Fujiwara, R., Shirai, T., Tanaka, T., Kondo, A. (2021/09) Reprogramming Escherichia coli pyruvate-forming reaction towards chorismate derivatives production, Metabolic Engineering, 67, 1-10
  2. Nonaka, D., Fujiwara, R., Hirata, Y., Tanaka, T*., Kondo, A. (2021/02) Metabolic engineering of 1,2-propanediol production from cellobiose using beta-glucosidase-expressing E. coli, Bioresource Technology, 329, 124858
  3. Sato, N., Kishida, M., Nakano, M., Hirata, Y., Tanaka T*. (2020/09) Metabolic engineering of shikimic acid-producing Corynebacterium glutamicum from glucose and cellobiose retaining its phosphotransferase system function and pyruvate kinase activities, Frontiers in Bioengineering and Biotechnology, 8, 569406
  4. Satowa, D., Fujiwara, R., Uchio, S., Nakano, M., Otomo, C., Hirata, T., Matsumoto, T., Noda, S., Tanaka, T., Kondo, A. (2020/07) Metabolic engineering of E. coli for improving mevalonate production to promote NADPH regeneration and enhance acetyl-CoA supply, Biotechnology and Bioengineeering, 117(7), 2153-2164
  5. Fujiwara, R., Noda, S.*, Tanaka, T.*, Kondo, A. (2020/01) Metabolic engineering of Escherichia coli for shikimate pathway derivative production from glucose–xylose co-substrate, Nature Communications, 11: 279
  6. Matsumoto, T., Mori, Y., Tanaka, T.*, Kondo, A. (2020/01) n-Butylamine production from glucose using a transaminase-mediated synthetic pathway in Escherichia coli, Journal of Bioscience and Bioengineering, 129(1), 99-103
  7. Matsuura, R., Kishida, M., Konishi, R., Hirata, Y., Adachi, N., Segawa, S., Imao, K., Tanaka, T.*, Kondo, A. (2019/06) Metabolic engineering to improve 1,5-diaminopentane production from cellobiose using β-glucosidase-secreting Corynebacterium glutamicum, Biotechnology and Bioengineering, 116(10), 2640-2651
  8. Takayama, S., Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Hirata, Y., Matsumoto, T., Tanaka, T.*, Kondo, A. (2018/11) Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe. Microbial Cell Factories, 17, 176
  9. Fujiwara, R., Noda, S., Tanaka, T.*, Kondo, A. (2018/10) Muconic acid production using gene-level fusion proteins in Escherichia coli, ACS Synthetic Biology, 7(11), 2698-2705
  10. Okano, K., Uematsu, G., Hama, S., Tanaka, T., Noda, H., Kondo, A., Honda, K. (2018/05) Metabolic engineering of Lactobacillus plantarum for direct L-lactic acid production from raw corn starch, Biotechnology Journal, 13(5), 1700517
  11. Gonçalves, G.A.L., Mori, Y., Tanaka, T., Kamiya, N. (2018/03) Casein-based scaffold for artificial cellulosome design., Process Biochemistry, 66, 140-145
  12. Matsumoto, T., Isogawa, Y., Tanaka, T.*, Kondo, A. (2018/01) Streptavidin-hydrogel prepared by sortase A-assisted click chemistry for enzyme immobilization on an electrode. Biosensors and Bioelectronics, 99, 56-61
  13. Matsumoto, T., Tanaka, T., Kondo, A. (Review) (2017/12) Engineering metabolic pathways in Escherichia coli for constructing a “microbial chassis” for biochemical production. Bioresource Technology, 245, 1362-1368
  14. Imao, K., Konishi, R., Kishida, M., Hirata, Y., Segawa, S., Adachi, N., Matsuura, R., Tsuge, Y., Matsumoto, T., Tanaka T., Kondo, A. (2017/12) 1,5-Diaminopentane production from xylooligosaccharides using metabolically engineered Corynebacterium glutamicum displaying beta-xylosidase on the cell surface. Bioresource Technology, 245, 1684-1691
  15. Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Takayama, S., Matsumoto, T., Tanaka, T.*, Kondo, A. (2017/08) Metabolic engineering of Schizosaccharomyces pombe via CRISPR-Cas9 genome editing for lactic acid production from glucose and cellobiose. Metabolic Engineering Communications, 5, 60-67
  16. Eguchi, Y., Kato, T., Tanaka, T., Maruyama, T. (2017/04) A DNA-gold nanoparticle hybrid hydrogel network prepared by enzymatic reaction. Chemical Communications, 53, 5802-5805
  17. Okano, K., Hama, S., Kihara, M., Noda, H., Tanaka, T., Kondo, A. (2017/03) Production of optically pure D-lactic acid from brown rice using metabolically engineered Lactobacillus plantarum, Applied Microbiology and Biotechnology, 101(5), 1869-1875
  18. Fujiwara R., Noda, S., Tanaka, T., Kondo, A. (2016/12) Styrene production from a biomass-derived carbon source using a coculture system of phenylalanine ammonia lyase and phenylacrylic acid decarboxylase-expressing Streptomyces lividans transformants, Journal of Bioscience and Bioengineering, 122(6), 730-735
  19. Matsumoto, T., Furuta, K., Tanaka, T., Kondo, A. (2016/11) Sortase A-Mediated Metabolic Enzyme Ligation in Escherichia coli, ACS Synthetic Biology, 5(11), 1284-1289
  20. Fujiwara, R., Noda, S., Kawai, Y., Tanaka, T., Kondo, A. (2016/09) 4-Vinylphenol production from glucose using recombinant Streptomyces mobaraense expressing Rhodobacter sphaeroides tyrosine ammonia lyase, Biotechnology Letters, 38(9), 1543-1549
  21. Nakayama, M., Sasaki, R., Ogino, C., Tanaka, T., Morita, K., Umetsu, M., Ohara, S., Tan, Z., Nishimura, Y., Akasaka, H., Sato, K., Numako, C., Takami, S., Kondo, A. (2016/07) Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo, Radiation Oncology, 11(1): 91
  22. Tanimura, K., Takashima, S., Matsumoto, T., Tanaka, T., Kondo, A. (2016/07) 2,3-Butanediol production from cellobiose using exogenous beta-glucosidase-expressing Bacillus subtilis, Applied Microbiology and Biotechnology, 100(13), 5781-5789
  23. Tanimura, K., Matsumoto, T., Nakayama, H., Tanaka, T., Kondo, A. (2016/07) Improvement of ectoine productivity by using sugar transporter-overexpressing Halomonas elongata, Enzyme and Microbial Technology, 89, 63-68
  24. Mori, Y., Nakazawa, H., Gonçalves, G.A.L., Tanaka, T., Umetsu, M., Kamiya, N. (2016/03) One-dimensional assembly of functional proteins: toward the design of an artificial cellulosome, Molecular Systems Design & Engineering, 1, 66-73
  25. Matsumoto, T., Isogawa, Y., Minamihata, K., Tanaka, T.*, Kondo, A. (2016/03) Twigged streptavidin polymer as a scaffold for protein assembly, Journal of Biotechnology, 225, 61-66
  26. Zhang, Y., Kumar, A., Hardwidge, P.R., Tanaka, T., Kondo, A., Vadlani, P.V. (2016/03) D-lactic acid production from renewable lignocellulosic biomass via genetically modified Lactobacillus plantarum, Biotechnology Progress, 32(2), 271-278
  27. Zhang, Y., Vadlani, P.V., Kumar, A., Hardwidge, P.R., Govind, R., Tanaka, T., Kondo, A. (2016/01) Enhanced D-lactic acid production from renewable resources using engineered Lactobacillus plantarum, Applied Microbiology and Biotechnology, 100(1), 279-288
  28. Tanaka, T., Kondo, A. (Review) (2015/11) Cell surface engineering of industrial microorganisms for biorefining applications, Biotechnology Advances, 33, 1403-1411
  29. Hata, Y., Matsumoto, T., Tanaka, T.*, Kondo, A. (2015/10) C-terminal-oriented immobilization of enzymes using sortase A-mediated technique, Macromolecular Bioscience, 15(10), 1375-1380
  30. Hama, S., Mizuno, S., Kihara, M., Tanaka, T., Ogino, C., Noda, H., Kondo, A. (2015/07) Production of D-lactic acid from hardwood pulp via mechanical milling followed by simultaneous saccharification and fermentation using metabolically engineered Lactobacillus plantarum, Bioresource Technology, 187, 167-172
  31. Jia, L., Goncalves, G., Takasugi, Y., Mori, Y., Noda, S., Tanaka, T., Ichinose, H., Kamiya, N. (2015/06) Effect of pretreatment methods on the synergism of cellulase and xylanase during the hydrolysis of bagasse, Bioresouce Technology, 185, 158-164
  32. Goncalves, G., Takasugi, Y., Jia, L., Mori, Y., Noda, S., Tanaka, T., Ichinose, H., Kamiya, N. (2015/05) Synergistic effect and application of xylanases as accessory enzymes to enhance the hydrolysis of pretreated bagasse, Enzyme and Microbial Technology, 72, 16-24
  33. Noda, S., Kawai, Y., Tanaka, T., Kondo, A. (2015/03) 4-Vinylphenol biosynthesis from cellulose as the sole carbon source using phenolic acid decarboxylase-and tyrosine ammonia lyase-expressing Streptomyces lividans, Bioresource Technology, 180, 59-65
  34. Tanaka, T., Kondo, A. (Review) (2015/02) Cell-surface display of enzymes by the yeast Saccharomyces cerevisiae for synthetic biology, FEMS Yeast Research, 15, 1-9
  35. Noda, S., Matsumoto, T., Tanaka, T., Kondo, A. (2015/01) Secretory production of tetrameric native full-length streptavidin with thermostability using Streptomyces lividans as a host, Microbial Cell Factories, 14(1): 5
  36. Matsumoto, T., Shimada, S., Hata, Y., Tanaka, T.*, Kondo, A. (2015/01) Multi-functional glycoside hydrolase: Blon_0625 from Bifidobacterium longum subsp. infantis ATCC 15697, Enzyme and Microbial Technology, 68, 10-14
  37. Tanaka, T., Hirata, Y., Nakano, M., Kawabata, H., Kondo, A. (2014) Creation of cellobiose and xylooligosaccharides-coutilizing Escherichia coli displaying both beta-glucosidase and beta-xylosidase on its cell surface., ACS Synthetic Biology , 3(7), 446-453
  38. Tsuge, Y., Kawaguchi, H., Sasaki, K., Tanaka, T., Kondo, A. (2014) Two-step production of D-lactate from mixed sugars by growing and resting cells of metabolically engineered Lactobacillus plantarum., Applied Microbiology and Biotechnology, 98(11), 4911-4918
  39. Ogino, C., Matsuda, T., Okazaki, F.,Tanaka, T., Kondo, A. (2014) The effect of combining signal sequences with the N28 fragment on GFP production in Aspergillus oryzae., Process Biochemistry, 49, 1078-1083
  40. Tan, Z., Sato, K., Takami, S., Numako, C., Umetsu, M., Soga, K., Nakayama, M., Sasaki, R., Tanaka, T., Ogino, C., Kondo, A., Yamamoto, K., Hashishin, T., Ohara, S. (2013) Particle size for photocatalytic activity of anatase TiO2 nanosheets with highly exposed {001} facets., RSC Advances, 3, 19268-19271
  41. Matsumoto, T., Shimada, S., Yamamoto, K., Tanaka, T.*, Kondo, A. (2013) Two-stage oxidation of glucose by an enzymatic bioanode., Fuel Cells, 13(6), 960-964
  42. Tsuge, Y., Tateno, T., Sasaki, K., Hasunuma, T., Tanaka, T., Kondo, A. (2013) Direct production of organic acids from starch by cell surface engineered Corynebacterium glutamicum in anaerobic conditions., AMB Express,3(1):72
  43. Ikeda, N., Miyamoto, M., Adachi, N., Nakano, M., Tanaka, T., Kondo, A. (2013) Direct cadaverine production from cellobiose using beta-glucosidase displaying Escherichia coli., AMB Express, 3(1), 67
  44. Miyazaki, T., Noda, S., Tanaka, T., Kondo, A. (2013) Hyper secretion of Thermobifida fusca β-glucosidase via a Tat-dependent signal peptide using Streptomyces lividans., Microbial Cell Factories, 12(1), 88
  45. Adachi, N., Takahashi, C., Murota, N., Yamaguchi, R., Tanaka, T., Kondo, A. (2013) Direct L-lysine production from cellobiose by Corynebacterium glutamicum displaying beta-glucosidase on its cell surface., Applied Microbiology and Biotechnology, 97(16), 7165-7172
  46. Yamamoto, K., Matsumoto, T., Shimada, S., Tanaka, T.*, Kondo, A. (2013) Starchy biomass-powered enzymatic biofuel cell based on amylases and glucose oxidase multi-immobilized bioanode., New Biotechnology, 30(5), 531-535
  47. Noda, S., Miyazaki, T.,Tanaka, T., Ogino, C., Kondo, A. (2013) High-level production of mature active-form Streptomyces mobaraensis transglutaminase via pro-transglutaminase processing using Streptomyces lividans as a host., Biochemical Engineering Journal, 74, 76-80
  48. Mori, A., Ozasa, S., Noda, S., Tanaka, T., Ichinose, H., Kamiya, N. (2013) Aligning an endoglucanase Cel5A from Thermobifida fusca on a DNA scaffold : potent design of an artificial cellulosome., Chemical Communications, 49(62), 6971-6973
  49. Tanimura, K., Nakayama, H., Tanaka, T., Kondo, A. (2013) Ectoine production from lignocellulosic biomass-derived sugars by engineered Halomonas elongata., Bioresource Technology, 142, 523-529
  50. Noda, S., Kawai, Y., Miyazaki, T,. Tanaka, T., Kondo, A. (2013) Creation of endoglucanase-secreting Streptomyces lividans for enzyme production using cellulose as the carbon source., Applied Microbiology and Biotechnology, 97(13), 5711-5720
  51. Joseph, A., Aikawa, S., Sasaki, K., Tsuge, Y., Matsuda, F., Tanaka, T., Kondo, A. (2013) Utilization of lactic acid bacterial genes in Synechocystis sp. PCC 6803 for the production of lactic acid., Bioscience, Biotechnology, and Biochemistry, 77(5), 966-970
  52. Kawai, Y., Noda, S., Ogino, C., Takeshima, Y., Okai, N., Tanaka, T., Kondo, A. (2013) p-Hydroxycinnamic acid production directly from cellulose using endoglucanase- and tyrosine ammonia lyase-expressing Streptomyces lividans., Microbial Cell Factories, 12(1), 45
  53. Tanaka, T., Matsumoto, S., Yamada, M., Yamada, R., Matsuda, F., Kondo, A. (2013) Display of active beta-glucosidase on the surface of Schizosaccharomyces pombe cells using novel anchor proteins., Applied Microbiology and Biotechnology, 97(10), 4343-4352
  54. Honjo, T,. Hoe, K., Tabayashi, S., Tanaka, T., Shimada, J., Goto, M., Matsuyama, H., Maruyama, T. (2013) Preparation of afinity membranes using thermally induced phase separation for one-step purification of recombinant proteins., Analytical Biochemistry, 434, 269-274
  55. Song,Y., Matsumoto, K., Tanaka, T., Kondo, A. Taguchi, S. (2013) Single-step production of polyhydroxybutyrate from starch by using α-amylase cell-surface displaying system of Corynebacterium glutamicum., Journal of Bioscience and Bioengineering, 115(1), 12-14
  56. Soma, Y., Inokuma, K., Tanaka, T., Ogino, C., Kondo, A., Okamoto, M., Hanai, T. (2012) Direct isopropanol production from cellobiose by engineered Escherichia coli using a synthetic pathway and a cell surface display system., Journal of Bioscience and Bioengineering, 114(1), 80-85
  57. Okazaki, F., Aoki, J., Tabuchi, S., Tanaka, T., Ogino, C., Kondo, A. (2012) Efficient heterologous expression and secretion in Aspergillus oryzae of a llama variable heavy-chain antibody fragment V-HH against EGFR., Applied Microbiology and Biotechnology, 96(1), 81-88
  58. Matsumoto, T., Tanaka, T.*, Kondo, A. (Review) (2012) Enzyme-mediated methodologies for protein modification and bioconjugate synthesis., Biotechnology Journal, 7(9), 1137-1146
  59. Tanaka, T., Yamada, R., Ogino, C., Kondo, A. (Review) (2012) Recent developments in yeast cell surface display toward extended applications in biotechnology., Applied Microbiology and Biotechnology, 95, 577-591
  60. Noda, S., Kitazono, E., Tanaka, T., Ogino, C., Kondo, A. (2012) Benzoic acid fermentation from starch and cellulose via a plant-like beta-oxidation pathway in Streptomyces maritimus., Microbial Cell Factories, 11(1) : 49
  61. Yamakawa, S., Yamada, R., Tanaka, T., Ogino, C., Kondo, A. (2012) Repeated fermentation from raw starch using Saccharomyces cerevisiae displaying both glucoamylase and alpha-amylase., Enzyme and Microbial Technology, 50(6-7), 343-347
  62. Matsumoto, T., Takase, R., Tanaka, T.*, Fukuda, H., Kondo, A. (2012) Site-specific protein labeling with amine-containing molecules using Lactobacillus plantarum sortase., Biotechnology Journal, 7(5), 642-648
  63. Matsumoto, T., Tanaka, T.*, Kondo, A. (2012) Sortase A-catalyzed site-specific coimmobilization on microparticles via streptavidin., Langmuir, 28(7), 3553-3557
  64. Maruyama, T., Tabayashi, S., Honjo, T., Hoe, K., Tanaka, T., Shimada, J., Goto, M., Matsuyama, H. (2012) Task-specific membranes for the isolation of recombinant proteins with peptide tags., RSC Advances, 2, 125-127
  65. Noda, S., Miyazaki, T., Tanaka, T., Ogino, C., Kondo, A. (2012) Production of Streptoverticillium cinnamoneum transglutaminase and cinnamic acid by recombinant Streptomyces lividans cultured on biomass-derived carbon sources., Bioresource Technology, 104, 648-651
  66. Nishimura, Y., Shishido, T., Ishii, J., Tanaka, T., Ogino, C., Kondo, A. (2011) Protein-encapsulated bio-nanocapsules production with ER membrane localization sequences., Journal of Biotechnology, 157(1), 124-129
  67. Tanaka, T., Kawabata, H., Ogino, C., Kondo, A. (2011) Creation of cellooligosaccharide-assimilating escherichia coil strain by displaying active beta-glucosidase on the cell surface via a novel anchor protein, Applied and Environmental Microbiology, 77(17), 6265-6270
  68. Yoshida, S., Okano, K., Tanaka, T., Ogino, C., Kondo, A. (2011) Homo-D-lactic acid production from mixed sugars using xylose-assimilating operon-integrated Lactobacillus plantarum.,  Applied Microbiology and Biotechnology, 92(1), 67-76.
  69. Saitoh, S., Tanaka, T., Kondo, A. (2011) Co-fermentation of cellulose/xylan using engineered industrial yeast strain OC-2 displaying both β-glucosidase and β-xylosidase., Applied Microbiology and Biotechnology, 91(6), 1553-1559
  70. Shinkawa, S., Okano, K., Yoshida, S., Tanaka, T., Ogino, C., Fukuda, H. and Kondo, A. (2011) Improved homo L-lactic acid fermentation from xylose by abolishment of the phosphoketolase pathway and enhancement of the pentose phosphate pathway in genetically modified xylose-assimilating Lactococcus lactis, Applied Microbiology and Biotechnology, 91(6), 1537-1544
  71. Yamada, R., Taniguchi, N., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2011) Direct ethanol production from cellulosic materials using a diploid strain of Saccharomyces cerevisiae with optimized cellulase expression., Biotechnology for Biofuels, 4: 8
  72. Noda, S., Miyazaki, T., Miyoshi, T., Miyake, M., Okai, N., Tanaka, T., Ogino C., Kondo, A. (2011) Cinnamic acid production using Streptomyces lividans expressing phenylalanine ammonia lyase ., Journal of Industrial Microbiology and Biotechnology, 38(5), 643-648
  73. Yamada, R., Yamakawa, S., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2011) Direct and efficient ethanol production from high-yielding rice using aSaccharomyces cerevisiae strain that express amylases., Enzyme and Microbial Technology, 48, 393-396
  74. Matsumoto, T., Sawamoto, S., Sakamoto, T., Tanaka, T.*, Fukuda, H., Kondo, A. (2011) Site-specific tetrameric streptavidin-protein conjugation using sortase A., Journal of Biotechnology, 152(1-2), 37-42
  75. Tsuchidate, T., Tateno, T., Okai, N., Tanaka, T., Ogino, C., Kondo, A. (2011) Glutamate production from b-glucan using endoglucanase-secreting Corynebacterium glutamicum., Applied Microbiology and Biotechnology, 90(3), 895-901
  76. Kondo, A., Tanaka, T., Hasunuma, T., Ogino C. (Review) (2010) Applications of yeast cell-surface display in bio-refinery., Recent Patent on Biotechnology, 4(3): 226-234
  77. Sakamoto, T., Sawamoto, S. Tanaka, T.*, Fukuda, H. Kondo, A. (2010) Enzyme-mediated site-specific antibody-protein modification using a ZZ domain as a linker., Bioconjugate Chemistry, 21(12), 2227-2233
  78. Fukui, Y., Maruyama, T., Iwamatsu, Y., Fujii, A., Tanaka, T., Ohmukai, Y., Matsuyama, H. (2010) Preparation of monodispersed polyelectrolyte microcapsules with high encapsulation efficiency by an electrospray technique., Colloids and Surfaces A, 370, 28-34
  79. Yamada, R., Tanaka, T., Ogino C., Kondo, A. (Review) (2010) Gene copy number and polyploidy on products formation in yeast., Applied Microbiology and Biotechnology, 88(4), 849-857
  80. Matsui, K., Karasaki, M., Segawa, M., Hwang, S. Y., Tanaka, T., Ogino, C., Kondo, A. (2010) Biofunctional TiO2 nanoparticle-mediated photokilling of cancer cells using UV irradiation., Medicinal Chemistry Communication, 1, 209-211
  81. Yanase, S., Hasunuma, T., Yamada, R., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Direct ethanol production from cellulosic materials at high temperature using the thermotolerant yeast Kluyveromyces marxianus displaying cellulolytic enzymes., Applied Microbiology and Biotechnology, 88(1), 381-388
  82. Shishido, T., Mieda, H., Hwang, S. Y., Nishimura, Y., Tanaka, T., Ogino, T., Fukuda, H., Kondo, A. (2010) Affibody-displaying bionanocapsules for specific drug delivery to HER2-expressing cancer cells., Bioorganic & Medicinal Chemistry Letters, 20(19), 5726-5731
  83. Saito, S., Hasunuma, T., Tanaka, T., Kondo, A. (2010) Co-fermentation of cellobiose and xylose using beta-glucosidase displaying diploid industrial yeast strain OC-2., Applied Microbiology and Biotechnology, 87(5), 1975-1982
  84. Noda, S., Ito, Y., Shimizu, N., Tanaka, T., Ogino, C., Kondo, A. (2010) Over-production of various secretory-form proteins in Streptomyces lividans., Protein Expression and Purification, 73, 198-202
  85. Tabuchi, S., Ito, J., Adachi, T., Ishida, H., Hata, Y., Okazaki, F., Tanaka, T., Ogino, C., Kondo, A. (2010) Display of both N- and C-terminal target fusion proteins on the Aspergillus oryzae cell surface using a chitin-binding module., Applied Microbiology and Biotechnology, 87(5), 1783-1789
  86. Yamada, R., Taniguchi, N., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Cocktail δ-integration: a novel method to construct cellulolytic enzyme expression ratio-optimized yeast strains., Microbial Cell Factories, 14;9, 32
  87. Koda, R., Numata, T., Hama, S., Tamalampudi, S., Nakashima, K., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Ethanolysis of rapeseed oil to produce biodiesel fuel catalyzed by Fusarium heterosporum lipase-expressing fungus immobilized whole-cell biocatalysts., Journal of Molecular Catalysis B, 66(1-2), 101-104
  88. Togawa, S., Ishii, J., Ishikura, A., Tanaka, T., Ogino, C., Kondo, A. (2010) Importance of asparagine residues at positions 13 and 26 on the amino-terminal domain of human somatostatin receptor subtype-5 in signalling., Journal of Biochemistry, 147(6), 867-873
  89. Iguchi, Y., Ishii, J., Nakayama, H., Ishikura, A., Izawa, K., Tanaka, T., Ogino, C., Kondo, A. (2010) Control of signalling properties of human somatostatin receptor subtype-5 by additional signal sequences on its amino-terminus in yeast., Journal of Biochemistry, 147(6), 875-884
  90. Ishii, J., Fukuda, N., Tanaka, T., Ogino, C., Kondo, A. (Review) (2010) Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling, FEBS Journal, 277(9), 1982-1995
  91. Yamakawa, S., Yamada, R., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Repeated batch fermentation from raw starch using a maltose transporter and amylase expressing diploid yeast strain. Applied Microbiology and Biotechnology, 87(1), 109-115
  92. Yanase, S., Yamada, R., Kaneko, S., Noda, H., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Ethanol production from cellulosic materials using cellulase-expressing yeast., Biotechnology Journal, 5, 449-455
  93. Fukuda, N., Ishii, J., Tanaka, T., Kondo A. (2010) The competitor-introduced Gγ recruitment system, a new approach for screening affinity‐enhanced proteins, FEBS Journal, 277(7), 1704-1712
  94. Tanaka, T., Masunari, S., Ishii, J., Wakamura, K., Segawa, M., Fukuda, H., Kondo, A. (2010) Displaying non-natural, functional molecules on yeast surfaces via biotin-streptavidin interaction., Journal of Biotechnology, 145(1) 79-83
  95. Okano, K., Zhang, Q. Yoshida, S., Tanaka, T., Fukuda, H., Kondo, A. (2010) D-lactic acid production from cellooligosaccharides and beta-glucan using L-LDH gene-deficient and endoglucanase-secreting Lactobacillus plantarum, Applied Microbiology and Biotechnology, 85(3), 643-50
  96. Horii, K., Adachi, T., Tanino, T., Tanaka, T., Kotaka, A., Sahara, H., Hashimoto, T., Kuratani, N., Shibasaki, S., Ogino, C., Noda, H., Hata, Y., Ueda, M., Kondo, A. (2010) Fatty acid production from butter using novel cutinase-displaying yeast., Enzyme and Microbial Technology, 46, 194-199
  97. Okano, K., Tanaka T., Ogino C., Fukuda H., Kondo, A. (Review) (2010) Biotechnological production of enantiomeric pure lactic acid from renewable resources: recent achievements, perspectives, and limits., Applied Microbiology and Biotechnology, 85(3), 413-23
  98. Yamada, R., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2010) Novel strategy for yeast construction using δ-integration and cell fusion to efficiently produce ethanol from raw starch, Applied Microbiology and Biotechnology, 85, 1491-1498
  99. Okano, K., Yoshida, S., Tanaka, T., Ogino C., Fukuda, H., Kondo, A. (2009) Improved production of homo-D-lactic acid via xylose fermentation by introduction of xylose assimilation genes and redirection of the phosphoketolase pathway to the pentose phosphate pathway in L-Lactate dehydrogenase gene-deficient Lactobacillus plantarum., Applied and Environmental Microbiology, 75(24), 7858-61
  100. Shishido, T., Azumi, Y., Nakanishi, T., Umetsu, M., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2009) Biotinylated bionanocapsules for displaying diverse ligands toward cell-specific delivery., Journal of Biochemistry, 146(6), 867-74
  101. Okano, K., Yoshida, S., Tanaka, T., Fukuda, H., Kondo, A. (2009) Homo D-lactic acid fermentation from arabinose by redirection of phosphoketolase pathway to pentose phosphate pathway in L-lactate dehydrogenase gene-deficient lactobacillus plantarum., Applied and Environmental Microbiology, 75(15), 5175-5178
  102. Zhou, Y., Kajiyama S., Itoh, K., Tanino, T., Fukuda N., Tanaka, T., Kondo, A., Fukui K. (2009) Development of an enzyme activity screening system for β-glucosidase-displaying yeasts using calcium alginate micro-beads and flow sorting., Applied Microbiology and Biotechnology, 84(2), 375-382
  103. Kaneko, S., Tanaka, T., Noda H., Fukuda, H., Akada, R., Kondo, A. (2009) Marker disruptive gene integration and URA3 recycling for multiple gene manipulation in Saccharomyces cerevisiae., Applied Microbiology and Biotechnology, 83(4), 783-789
  104. Tateno, T., Hatada, K., Tanaka, T., Fukuda, H., Kondo, A. (2009) Development of novel cell surface display in Corynebacterium glutamicum using porin., Applied Microbiology and Biotechnology, 84, 733-739
  105. Ito, J., Kosugi A., Tanaka T., Kuroda, K., Shibasaki, S., Ogino, C., Ueda, M., Fukuda, H., Doi, R.H., Kondo, A. (2009) Regulation of the display ratio of enzymes on the Saccharomyces cerevisiae cell surface by the immunoglobulin G and cellulosomal enzyme binding domains., Applied and Environmental Microbiology, 75(12), 4149-4154
  106. Tateno, T., Okada, Y., Tsuchidate, T., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2009) Direct production of cadaverine from soluble starch using Corynebacterium glutamicum coexpressing α-amylase and lysine decarboxylase., Applied Microbiology and Biotechnology, 82(1), 115-121
  107. Okano, K., Zhang, Q., Shinkawa, S., Yoshida, S., Tanaka, T., Fukuda, H., Kondo, A. (2009) Efficient production of optically pure D-lactic acid from raw corn starch using genetically modified L-lactate dehydrogenase gene-deficient and α-amylase-secreting Lactobacillus plantarum., Applied and Environmental Microbiology, 75(2), 462-467
  108. Horii, K., Adachi T., Matsuda T., Tanaka, T., Sahara H., Shibasaki S., Ogino C., Hata Y., Ueda M., Kondo, A. (2009) Improvement of isoflavone aglycones production using β-glucosidase secretory produced in recombinant Aspergillus oryzae., Journal of Molecular Catalysis B, 59(4), 297-301
  109. Shishido, T., Kurata, N., Yoon, M., Tanaka, T., Yamaji, H., Fukuda, H., Kondo, A. (2009) A high-level expression vector containing selectable marker for continuous production of recombinant protein in insect cells., Biotechnology Letters, 31, 623-627
  110. Yamada, R., Bito, Y., Adachi, T., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2009) Efficient production of ethanol from raw starch by a mated diploid Saccharomyces cerevisiae with integrated α-amylase and glucoamylase genes., Enzyme and Microbial Technology, 44, 344-349
  111. Shishido, T., Yonezawa, D., Iwata K., Tanaka, T., Ogino, C., Fukuda, H., Konodo, A. (2009) Construction of arginine-rich peptide displaying bionanocapsules., Bioorganic & Medicinal Chemistry Letters, 19(5), 1473-1476
  112. Ishii, J., Izawa, K., Matsumura, S., Wakamura, K., Tanino T., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2009) A simple and immediate method for simultaneously evaluating expression level and plasmid maintenance in yeast., Journal of Biochemistry, 145(6), 701-708
  113. Fukuda, N., Ishii, J., Tanaka, T., Fukuda, H., Kondo, A. (2009) Construction of a novel detection system for protein-protein interactions using yeast G-protein signaling., FEBS Journal, 276, 2636-2644
  114. Horii, K., Adachi, T., Tanino, T., Tanaka, T., Sahara, H., Shibasaki, S., Ogino C., Hata, Y., Ueda, M., Kondo, A. (2009) Evaluation of cell surface-displayed protein stability against simulated gastric fluid, Biotechnlogy Letter, 31(8), 1259-1264
  115. Okano, K., Qiao, Z., Kimura, S., Narita, J., Tanaka, T., Fukuda, H., Kondo, A., (2008) System using tandem repeats of the cA peptidoglycan-binding domain from Lactococcus lactis for display of both N- and C-terminal fusions on cell surfaces of lactic acid bacteria., Applied and Environmental Microbiology, 74(4), 1117-1123
  116. Tanaka, T., Yamamoto, T. Tsukiji, S. and Nagamune T. (2008) Site-specific protein modification on living cells catalyzed by Sortase., ChemBioChem. 9(5), 802-807
  117. Fukuda, N., Ishii, J., Tanaka, T., Fukuda, H., Ohnishi, N., Kondo, A. (2008) Rapid and efficient selection of yeast displaying a target protein using thermo-responsive magnetic nanoparticles., Biotechnology Progress, 24(2), 352-357
  118. Ishii,J., Tanaka, T., Matsumura, S., Tatematsu, K., Kuroda, S., Ogino, C., Fukuda, H., Kondo, A. (2008) Yeast-based fluorescence reporter assay of G protein-coupled receptor signalling for flow cytometric screening: FAR1-disruption recovers loss of episomal plasmid caused by signalling in yeast, Journal of Biochemistry, 143(5), 667-674
  119. Saitoh, S., Tanaka, T., Kondo A. (2008) Breeding of industrial diploid yeast strain with chromosomal integration of multiple β-glucosidase genes., Journal of Bioscience and Bioengineering, 106(6), 594-597
  120. Kurata, N., Shishido, T., Muraoka, M., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A. (2008) Specific protein delivery to target cells by antibody-displaying bionanocapsules., Journal of Biochemistry, 144(6), 701-707
  121. Nakamura, N., Yamada, R., Katahira, S., Tanaka, T., Fukuda, H., Kondo, A. (2008) Effective xylose/cellobios co-fermentation and ethanol production by xylose-assimilating S. cerevisiae via expression of β-glucosidase on its cell surface., Enzyme and Microbial Technology, 43, 233-236
  122. Katahira, S., Ito, M., Takema, H., Fujita, Y., Tanino, T., Tanaka, T., Fukuda., H., Kondo, A. (2008) Improvement of ethanol productivity during xylose and glucoseco-fermentation by xylose-assimilating S. cerevisiae via expression of glucose transporter Sut1., Enzyme and Microbial Technology, 43, 115-119
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総説・解説等

  1. 藤原良介, 野田修平, 田中勉, 物質生産とエネルギー獲得を独立させるパラレル型代謝工学技術, バイオサイエンスとインダストリー, Vol. 78(4), 316-317 (2020/07)
  2. 藤原良介, 田中勉, 野田修平, 微生物に糖を目的別に使い分けさせる新技術によるポリマー原料の生産性向上, クリーンエネルギー, vol. 29(5), 20-25 (2020/05)
  3. 田中勉, 近藤昭彦, 分裂酵母を用いた有機酸生産技術の開発, ケミカルエンジニヤリング, 特集=革新技術が拓く新しい可能性, vol. 63(7), 7-10 (2018/07)
  4. Matsumoto, T., Tanaka, T., Kondo, A. Sortase A-Assisted Metabolic Enzyme Ligation in Escherichia coli for Enhancing Metabolic Flux. In: Braman J. (eds) Synthetic Biology, Methods in Molecular Biology, vol 1772. pp125-136 Humana Press, New York, NY (2018/05)
  5. 松本拓也, 田中勉, Sortase Aを用いたタンパク質配向固定化技術の開発, 細胞・生体分子の固定化と機能発現, 第3章, 18-25 (2018)
  6. 岡野憲司, 田中勉, 本田孝祐, 近藤昭彦, 乳酸菌の遺伝子操作技術の進展, 酵母菌・麹菌・乳酸菌の産業応用展開, 第III編 乳酸菌 第2章, シーエムシー出版, 201-207 (2018/01)
  7. 岡野憲司, 濵真司, 田中勉, 野田秀夫, 近藤昭彦, 未利用バイオマスからのD-乳酸生産に向けた乳酸菌の代謝工学研究, JATAFFジャーナル, Vol.5, No.3, 33-37 (2017)
  8. Bisaria, V., Kondo, A. Bioprocessing of Renewable Resources to Commodity Bioproducts, Wiley (2014)
    Chapter 13, Lactic acid, Okano, K., Tanaka, T., Kondo, A. 353-380
  9. 近藤昭彦, 田中勉, 遺伝子工学, 1章, 遺伝子工学序論, 化学同人, 1-14 (2012)
  10. 近藤昭彦, 田中勉, 遺伝子工学, 15章, バイオエネルギー, バイオ材料, 化学同人, 206-216 (2012)
  11. 近藤昭彦, 荻野千秋, 蓮沼誠久, 田中勉, 中島一紀, 次世代燃料・化成品原料製造に向けたバイオリファイナリー戦略, 生物工学, 88(7), 333-335 (2010)
  12. 近藤昭彦, 荻野千秋, 蓮沼誠久, 田中勉, 中島一紀, バイオマスからのバイオ燃料生産に向けた戦略, バイオインダストリー, Vol. 11, 6-12 (2010)
  13. 近藤昭彦, 荻野千秋, 蓮沼誠久, 田中勉, 中島一紀, エコバイオリファイナリー, 第6章, バイオエネルギーと新プラットフォーム形成, シーエムシー出版, 82-91 (2010)
  14. 石井純, 田中勉, 荻野千秋, 近藤昭彦, シングルセル解析の最前線, 第3章4, フローサイトメトリーとGFPレポーターによるG蛋白質シグナルのシングルセル解析, シーエムシー出版, 158-165 (2010)
  15. 近藤昭彦, 荻野千秋, 田中勉, 生体分子と無機材料を融合した中空バイオナノ粒子による新しいがん治療戦略, 工業材料, 61-64 (2009)
  16. 田中勉, 荻野千秋, 近藤昭彦, 第二世代バイオ燃料の開発と応用展開, 第7章1, 未来型CBP法による先導技術の展開, シーエムシー出版, 133-149 (2009)
  17. 近藤昭彦, 福田秀樹, 荻野千秋, 田中勉, 第二世代バイオ燃料の開発と応用展開, 第1章1, バイオ燃料の最新動向, シーエムシー出版, 3-7 (2009)
  18. 田中勉, 荻野千秋, 近藤昭彦, 細胞表層提示技術を用いた微生物の高機能化と有用物質生産, 月刊バイオインダストリー, 25(8), 13-20 (2008)
  19. 荻野千秋, 田中勉, 福田秀樹, 近藤昭彦, 微生物によるものづくり, 第6章3  バイオエタノール, シーエムシー出版, 310-315 (2008)
  20. 荻野千秋, 田中勉, 福田秀樹, 近藤昭彦, バイオリファイナリーが求める植物バイオマス, 月刊バイオインダストリー, 25(4), 11-19 (2008)
  21. 近藤昭彦, 石井純, 田中勉, タンパク質間相互作用とシグナル伝達解析, 未来材料, 6, 40-45 (2007)