メンバー紹介

准教授石井 純 Jun Ishii

経歴

2002/03
神戸大学 工学部応用化学科 卒業
2004/03
神戸大学 大学院自然科学研究科 応用化学専攻 博士前期課程 修了
2008/03
神戸大学 大学院自然科学研究科 分子物質科学専攻 博士後期課程 修了
博士(工学)
2008/08
神戸大学 自然科学系先端融合研究環 特命助教
2012/04
神戸大学 自然科学系先端融合研究環 特命准教授
2013/04
神戸大学 自然科学系先端融合研究環 准教授
2016/04
神戸大学 大学院科学技術イノベーション研究科 准教授

発表論文

  1. Nambu-Nishida, Y., Sakihama, Y., Ishii, J., Hasunuma, T., Kondo, A. (2018) Selection of yeast Saccharomyces cerevisiae promoters available for xylose cultivation and fermentation, Journal of Bioscience and Bioengineering, 125(1), 76-86
  2. Hara, Y. K., Kobayashi, J., Yamada, R., Sasaki, D., Kuriya, Y., Hirono-Hara, Y., Ishii, J., Araki, M., Kondo, A. (2017) Transporter Engineering in Biomass Utilization by Yeast, FEMS Yeast Research, 17(7), fox061
  3. Fukuda, N., Kaishima, M., Ishii, J., Honda, S. (2017) Positive detection of GPCR antagonists using a system for inverted expression of a fluorescent reporter gene. ACS Synthetic Biology, 6(8), 1554-1562
  4. Morita, K., Nomura, Y., Ishii, J., Matsuda, F., Kondo, A., Shimizu, H. (2017) Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner-Doudoroff pathway-related genes in Saccharomyces cerevisiae for improvement of isobutanol production, Journal of Bioscience and Bioengineering, 124(3), 263-270
  5. A. Prima, Hara, Y. K., A. C. Djohan, Kashiwagi, N., P. Kahar, Ishii, J., Nakayama, H., Okazaki, F., B. Prasetya, Kondo, A., Yopi, Ogino, C. (2017) Glutathione production from mannan-based bioresource by mannanase/mannosidase expressing Saccharomyces cerevisiae, Bioresource Technology, 245, 1400-1406
  6. Ryo, S., Ishii, J., Matsuno, T., Nakamura, Y., Matsubara, D., Tominaga, M., Kondo, A. (2017) Positive feedback genetic circuit incorporating a constitutively active mutant Gal3 into yeast GAL induction system., ACS Synthetic Biology, 6(6), 928-935
  7. Fukutani, Y., Ishii, J., Kondo, A., Ozawa, T., Matsunami, H., Yohda, M. (2017) Split luciferase complementation assay for the analysis of G protein-coupled receptor ligand response in Saccharomyces cerevisiae. Biotechnology and Bioengineering, 114(6): 1354-1361
  8. Nishimura, Y., Ezawa, R., Ishii, J., Ogino, C., Kondo, A. (2017) Affibody-displaying bio-nanocapsules effective in EGFR, typical biomarker, expressed in various cancer cells., Bioorganic & Medicinal Chemistry Letters, 27(2), 336-341
  9. Kaishima, M., Ishii, J., Matsuno, T., Fukuda, N., Kondo, A. (2016) Expression of varied GFPs in Saccharomyces cerevisiae: codon optimization yields stronger than expected expression and fluorescence intensity., Scientific Reports,6:35932
  10. Yamamoto, K., Hara, Y. K., Morita, T., Nishimura, A., Sasaki, D., Ishii, J., Ogino, C., Kizaki, N., Kondo, A. (2016) Enhancement of astaxanthin production in Xanthophyllomyces dendrorhous by efficient method for the complete deletion of genes., Microbial Cell Factories,15(1):155
  11. Ishii, J., Okazaki, F., Djohan, C. Apridah., Hara, Y. K., Asai-Nakashima, N., Teramura, H., Andriani, A., Tominaga, M., Wakai, S., Kahar, P., Yopi, Prasetya, B., Ogino, C., Kondo, A. (2016) From mannan to bioethanol: cell surface co-display of β-mannanase and βmannosidase on yeast Saccharomyces cerevisiae., Biotechnology for Biofuels, 9, 188
  12. Inokuma, K., Bamba, T., Ishii, J., Ito, Y., Hasunuma, T., Kondo, A. (2016) Enhanced cell-surface display and secretory production of cellulolytic enzymes with Saccharomyces cerevisiae Sed1 signal peptide., Biotechnology and Bioengineering, 113(11), 2358-2366
  13. Nakamura, Y., Hashimoto, T., Ishii, J., Kondo, A. (2016) Dual-color reporter switching system to discern dimer formations of G-protein-coupled receptors using Cre/loxP site-specific recombination in yeast., Biotechnology and Bioengineering, 113(10), 2178-2190
  14. Fukuda, N., Kaishima, M., Ishii, J., Kondo, A., Honda, S. (2016) Continuous crossbreeding of sake yeasts using growth selection systems for a-type and α-type cells., AMB Express,6:45
  15. Nakamura, Y., Ishii, J., Kondo, A.(Review) (2016) Current techniques for studying oligomer formations of G-protein-coupled receptors using mammalian and yeast cells., Current Medicinal Chemistry,23(16)1638-1656
  16. Hattan, J., Shindo, K., Ito, T., Shibuya, Y., Watanabe, A., Tagaki, C., Ohno, F., Sasaki, T., Ishii, J., Kondo, A., Misawa, N. (2016) Identification of a novel hedycaryol synthase gene isolated from Camellia brevistyla flowers andfloral scent of Camellia cultivars., Planta, 243(4), 959-972
  17. Shen, L., Nishimura, Y., Matsuda, F., Ishii, J., Kondo, A. (2016) Overexpressing enzymes of the Ehrlich pathway and deleting genes of the competing pathway in Saccharomyces cerevisiae for increasing 2- phenylethanol production from glucose.,  Journal of Bioscience and Bioengineering, 122(1), 34-39
  18. Tsuge, Y., Kudou, M., Kawaguchi, H., Ishii, J., Hasunuma, T., Kondo, A. (2016) FudC, a protein primary responsible for furfural detoxification in Corynebacterium glutamicum., Applied Microbiology and Biotechnology, 100(6), 2685-2692
  19. Hiraoka, R., Funasaki, Y., Ishii, J., Maruyama, T. (2015) Rational design of degradable polyanion for layer-by-layer assembly for encapsulation and release of cationic functional biomolecules.,Chemical Communications, 51(98): 17447-17450
  20. Kaishima, M., Ishii, J., Fukuda, N., Kondo, A. (2015) Gγ recruitment systems specifically select PPI and affinity-enhanced candidate proteins that interact with membrane protein targets., Scientific Reports, 5, 16723
  21. Hasunuma, T., Ishii, J., Kondo, A. (Review) (2015) Rational design and evolutional fine tuning of Saccharomyces cerevisiae for biomass breakdown., Current Opinion in Chemical Biology, 29: 1-9
  22. Nakamura, Y., Ishii, J., Kondo, A. (2015) Applications of yeast-based signaling sensor for characterization of antagonist and analysis of site-directed mutants of the human serotonin 1A receptor., Biotechnology and Bioengineering, 112(9), 1906-1915
  23. Ida, K., Ishii, J., Matsuda, F., Kondo, T., Kondo, A. (2015) Eliminating the isoleucine biosynthetic pathway to reduce competitive carbon outflow during isobutanol production by Saccharomyces cerevisiae., Microbial Cell Factories ,14: 62
  24. Mohamed suffian, I.F., Nishimura, Y., Morita,K., Nakamura-Tsuruta, S., Al-Jamal, K.T., Ishii, J., Ogino, C., Kondo, A. (2015) Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles., Journal of Nanobiotechnology, 13(1): 15
  25. Inokuma, K., Ishii, J., Hara, K.Y., Mochizuki, M., Hasunuma, T., Kondo, A. (2015) Complete genome sequence of Kluyveromyces marxianus NBRC1777, a nonconventional thermotolerant yeast., Genome Announcements , 3(2), e00389-15
  26. Fukutani, Y., Hori, A., Tsukada, S., Sato, R., Ishii, J., Kondo, A., Matsunami, H., Yohda, M. (2015) Improving the odorant sensitivity of olfactory receptor-expressing yeast with accessory proteins., Analytical Biochemistry, 471, 1-8
  27. Suzuki, H., Ishii, J., Kondo, A., Yoshida, K. (2015) Polyamino acid display on cell surfaces enhances salt and alcohol tolerance of Escherichia coli., Biotechnology Letters, 37(2), 429-435
  28. Takenaka, M., Miyachi, Y., Ishii, J., Ogino, C., Kondo, A. (2015) The mapping of yeast’s G-protein coupled receptor with an atomic force microscope., Nanoscale, 7, 4956-4963
  29. Inokuma, K., Yoshida, T., Ishii, J., Hasunuma, T., Kondo, A. (2015) Efficient co-displaying and artificial ratio control of α-amylase and glucoamylase on the yeast cell surface by using combinations of different anchoring domains., Applied Microbiology and Biotechnology, 99(4), 1655-1663
  30. Tsuge, Y., Hori, Y., Kudou, M., Ishii, J., Hasunuma, T., Kondo, A. (2014) Detoxification of furfural in Corynebacterium glutamicum under aerobic and anaerobic conditions., Applied Microbiology and Biotechnology, 98(20), 8675-8683
  31. Kaishima, M., Fukuda, N., Ishii, J., Kondo, A. (2014) Desired alteration of protein affinities: competitive selection of protein variants using yeast signal transduction machinery., PLoS ONE, 9(9): e108229
  32. Nakamura, Y., Ishii, J., Kondo, A. (2014) Construction of a yeast-based signaling biosensor for human angiotensin Ⅱtype 1 receptor via functional coupling between Asn295-mutated receptor and Gpa1/Gi3 chimeric Gα., Biotechnology and Bioengineering, 111(11), 2220-2228
  33. Nakamura, Y., Ishii, J., Kondo, A. (2014) Signaling assays for detection of human G-protein-coupled receptors in yeast., Bio-protocol, 4(16), e1206
  34. Nishimura, Y., Ishii, J., Ogino, C., Kondo, A. (Review) (2014) Genetic engineering of bio-nanoparticles for drug delivery: a review., Journal of Biomedical Nanotechnology, 10(9), 2063-2085
  35. Ishii, J., Kondo, T., Makino, H., Ogura, A., Matsuda, F., Kondo, A. (2014) Three gene expression vector sets for concurrently expressing multiple genes in Saccharomyces cerevisiae., FEMS Yeast Research, 14(3), 399-411
  36. Nishimura, Y., Takeda, K., Ezawa, R., Ishii, J., Ogino, C., Kondo, A. (2014) A display of pH-sensitive fusogenic GALA peptide facilitates endosomal escape from a Bio-nanocapsule via an endocytic uptake pathway., Journal of Nanobiotechnology, 21(1), 11
  37. Ishii, J., Oda, A., Togawa, S., Fukao, A., Fujiwara, T., Ogino, C., Kondo, A. (2014) Microbial fluorescence sensing for human neurotensin receptor type 1 using Gα-engineered yeast cells., Analytical Biochemistry, 446, 37-43
  38. Nakamura, Y., Takemoto, N., Ishii, J., Kondo, A. (2014) Simultaneous method for analyzing dimerization and signaling of G-protein-coupled receptor in yeast by dual-color reporter system., Biotechnology and Bioengineering, 111(3), 586-596
  39. Matsuda, F., Ishii, J., Kondo, T., Ida, K., Tezuka, H,. Kondo, A. (2013) Increased isobutanol production in Saccharomyces cerevisiae by eliminating competing pathways and resolving cofactor imbalance., Microbial Cell Factories, 12:119
  40. Nakamura, Y., Ishii, J., Kondo, A. (2013) Bright fluorescence monitoring system utilizing Zoanthus sp. green fluorescent protein (ZsGreen) for human G-protein-coupled receptor signaling in microbial yeast cells., PLoS ONE, 8(12) e82237
  41. Nishimura, Y., Mieda, H., Ishii, J., Ogino, Fujiwara, T., Kondo, A. (2013) Targeting cancer cell-specific RNA interference by siRNA delivery using a complex carrier of affibody-displaying bio-nanocapsules and liposomes., Journal of Nanobiotechnology, 11, 19
  42. Matsuda, F., Shirai, T,. Ishii, J., Kondo, A. (2013) Regulation of central carbon metabolism in Saccharomyces cerevisiae by metabolic inhibitors., Journal of Bioscience and Bioengineering,116(1), 59-64
  43. Nakamura, Y., Ishii, J., Kondo, A. (2013) Rapid, facile detection of heterodimer partners for target human G-protein-coupled receptors using a modified split-ubiquitin membrane yeast two-hybrid system., PLoS ONE, 8(6), e66793
  44. Hasunuma, T., Okazaki, F., Okai, N., Hara, K.Y., Ishii, J., Kondo, A. (Review) (2013) A review of enzymes and microbes for lignocellulosic biorefinery and the possibility of their application to consolidated bioprocessing technology., Bioresourse Technology , 135, 513-522
  45. Nishimura, Y., Takeda, K., Ishii, J., Ogino, C., Kondo, A. (2013) An affinity chromatography method used to purify His-tag-displaying bio-nanocapsules., Journal of Virological Methods, 189(2), 393-396
  46. Nishimura, Y., Mimura, W., Suffian, IMF, Amino, T., Ishii, J., Ogino C., Kondo, A. (2013) Granting specificity for breast cancer cells using a Hepatitis B core particle with a HER2-targeted affibody molecule., Journal of Biochemistry, 153(3), 251-256
  47. Kondo, A., Ishii, J., Hara, K.Y., Hasunuma, T., Matsuda, F. (Review) (2013) Development of microbial cell factories for bio-refinery through synthetic bioengineering., Journal of Biotechnololgy, 163(2), 204-216
  48. Ishii, J., Yoshimura, K., Hasunuma, T., Kondo, A., (2013) Reduction of furan derivatives by overexpressing NADH-dependent Adh1 improves ethanol fermentation using xylose as sole carbon source with Saccharomyces cerevisiae harboring XR-XDH pathway., Applied Microbiology and Biotechnology, 97(6), 2597-2607
  49. Suga, H., Matsuda, F., Hasunuma, T., Ishii, J., Kondo, A. (2013) Implementation of a transhydrogenase-like shunt to counter redox imbalance during xylose fermentation in Saccharomyces cerevisiae., Applied Microbiology and Biotechnology, 97(4), 1669-1678
  50. Matsuda, F., Kondo, T., Ida, K., Tezuka, H., Ishii, J., Kondo, A. (2012) Construction of an artificial pathway for isobutanol biosynthesis in the cytosol of Saccharomyces cerevisiae., Bioscience, Biotechnlolgy, and Biochemistry, 76(11), 2139-2141
  51. Nishimura, Y., Ishii, J., Okazaki, F., Ogino, C., Kondo, A. (2012) Complex carriers of affibody-displaying bio-nanocapsules and composition-varied liposomes for HER2-expressing breast cancer cell-specific protein delivery., Journal of Drug Targeting., 20(10), 897-905
  52. Fukutani, Y., Ishii, J., Noguchi, K., Kondo, A., Yohda, M. (2012) An improved bioluminescence-based signaling assay for odor sensing with a yeast expressing a chimeric olfactory receptor., Biotechnology and Bioengineering, 109(12), 3143-3151
  53. Ishii, J., Yoshimoto, N., Tatematsu, K., Kuroda, S., Ogino, C., Fukuda, H., Kondo, A. (2012) Cell wall trapping of autocrine peptides for human g-protein-coupled receptors on the yeast cell surface., PLoS ONE, 7(5) : e37136
  54. Ishii, J., Moriguchi, M., Hara, K.Y., Shibasaki, S., Fukuda, H., Kondo, A. (2012) Improved identification of agonist-mediated Gα(i)-specific human G-protein-coupled receptor signaling in yeast cells by flow cytometry., Analytical Biochemistry, 426(2), 129-133
  55. Hara, K. Y., Kim, S., Kiriyama, K., Yoshida, H., Arai, S., Ishii, J., Ogino, C., Fukuda, H., Kondo, A. (2012) An energy-saving glutathione production method from low-temperature cooked rice using amylase-expressing Saccharomyces cerevisiae., Biotechnology Journal, 7(5), 686-689
  56. Ryo, S., Ishii, J., Iguchi, Y., Fukuda, N., Kondo, A. (2012) Transplantation of the GAL regulon into G-protein signaling circuitry in yeast., Analytical Biochemistry, 424(1), 27-31
  57. Kondo, T., Tezuka, H., Ishii, J., Matsuda, F., Ogino C., Kondo, A. (2012) Genetic engineering to enhance the Ehrlich pathway and alter carbon flux for increased isobutanol production from glucose by Saccharomyhces cerevisiae., Journal of Biotechnology, 159(1-2), 32-7
  58. Nishimura, Y., Shishido, T., Ishii, J., Tanaka, T., Ogino, C., Kondo, A.(2012) Protein-encapsulated bio-nanocapsules production with ER membrane localization sequences. Journal of Biotechnology.,157(1), 124-129.
  59. Fukutani, Y., Nakamura, T., Yorozu, M., Ishii, J., Kondo, A., Yohda, M. (2012) The N-terminal replacement of an olfactory receptor for the development of a yeast-based biomimetic odor sensor. Biotechnology and Bioengineering., 109(1), 205-212.
  60. Matsuda, F., Furusawa, C., Kondo, T., Ishii, J., Shimizu, H., Kondo, A.(2011) Engineering strategy of yeast metabolism for higher alcohol production. Microbial Cell Factories., 10:70.
  61. Fukuda, N., Ishii, J., Kondo, A. (2011) Gγ recruitment system incorporating a novel signal amplification circuit to screen transient protein-protein interactions., FEBS Journal, 278, 3086-3094.
  62. Fukuda, N., Ishii, J., Kaishima, M., Kondo, A. (2011) Amplification of agonist stimulation of human G-protein-coupled receptor signaling in yeast., Analytical Biochemistry, 417, 182-187.
  63. Hasunuma, T., Sanda, T., Yamada, R., Yoshimura, K., Ishii, J., Kondo, A. (2011) Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae., Microbial Cell Factories, 10(1): 2.
  64. Tanino, T., Hotta, A., Ito, T., Ishii, J., , Yamada, R., Hasunuma, T., Ogino, C., Ohmura, N., Ohshima, T., Kondo, A. (2010) Construction of a xylose-metabolizing yeast by genome integration of xylose isomerase gene and investigation of the effect of xylitol on fermentation., Applied Microbiology and Biotechnology, 88, 1215-1221
  65. Iguchi, Y., Ishii, J., Nakayama, H., Ishikura, A., Izawa, K., Tanaka, T., Ogino, C., Kondo, A. (2010) Control of signalling properties of human somatostatin receptor subtype-5 by additional signal sequences on its amino-terminus in yeast., Journal of Biochemistry, 147(6), 875-884.
  66. Togawa, S., Ishii, J., Ishikura, A., Tanaka, T., Ogino, C., Kondo, A. (2010) of asparagine residues at positions 13 and 26 on the amino-terminal domain of human somatostatin receptor subtype-5 in signalling., Journal of Biochemistry, 147(6), 867-873.
  67. Ishii, J., Fukuda, N., Tanaka, T., Ogino, C., Kondo, A. (Review) (2010)Protein-protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling., FEBS Journal, 277(9), 1982-1995.
  68. Fukuda, N., Ishii, J., Tanaka, T., Kondo, A. (2010)The competitor-introducedGγ recruitment system, a new approach for screening affinity-enhanced proteins., FEBS Journal, 277(7), 1704-1712.
  69. Tanaka, T., Masunari, S., Ishii, J., Wakamura, K., Segawa, M., Fukuda, H., Kondo, A. (2010) Displaying non-natural, functional molecules on yeast surfaces via biotin-streptavidin interaction., Journal of Biotechnology, 145, 79-83.
  70. Ishii, J., Izawa, K., Matsumura, S., Wakamura, K., Tanino T., Tanaka, T., Ogino, C., Fukuda, H., Kondo, A.(2009) A simple and immediate method for simultaneously evaluating expression level and plasmid maintenance in yeast., Journal of Biochemistry,145(6), 701-708. 
  71. Fukuda, N., Ishii, J., Tanaka, T., Fukuda, H., Kondo, A.(2009) Construction of a novel detection system for protein-protein interactions using yeast G-protein signaling., FEBS Journal, 276(9), 2636-2644 .
  72. Ishii, J., Tanaka, T., Matsumura, S., Tatematsu, K., Kuroda, S., Ogino, C., Fukuda, H., Kondo, A. (2008) Yeast-based fluorescence reporter assay of G protein-coupled receptor signalling for flow cytometric screening: FAR1-disruption recovers loss of episomal plasmid caused by signalling in yeast., Journal of Biochemistry, 143(5), 667-674.
  73. Fukuda, N., Ishii, J., Tanaka T., Fukuda, H., Ohnishi, N., Kondo, A. (2008) Rapid and efficient selection of yeast displaying a target protein using thermo-responsive magnetic nanoparticles., Biotechnology Progress, 24(2), 352-357.
  74. Shibasaki, S., Sakata, K., Ishii, J., Kondo, A., Ueda, M. (2008) Development of a yeast protein fragment complementation assay (PCA) system using dihydrofolate reductase (DHFR) with specific additives. Applied Microbiology and Biotechnology, 80(4), 735-743.
  75. Fukuda, N, Ishii, J., Shibasaki, S, Ueda, M, Fukuda, H, Kondo, A.(2007) High-efficiency recovery of target cells using improved yeast display system for detection of protein-protein interactions., Applied Microbiology and Biotechnology, 76(1), 151-158
  76. Shibasaki S, Kawabata A, Ishii, J., Yagi S, Kadonosono T, Kato M, Fukuda N, Kondo A, Ueda M. (2007) Construction of a novel synergistic system for production and recovery of secreted recombinant proteins by the cell surface engineering. Applied Microbiology and Biotechnology, 75(4), 821-828.
  77. Ishii, J., Matsumura, S., Kimura, S., Tatematsu, K., Kuroda, S., Fukuda, H., Kondo, A. (2006) Quantitative and dynamic analyses of G protein-coupled receptor signaling yeast using Fus1, enhanced green fluorescence protein (EGFP), and His3 fusion protein., Biotechnology Progress, 22, 954-960.

総説・解説等

  1. 柘植謙爾, 石井純, 荒木通啓, 近藤昭彦, ゲノム合成の潮流のインパクト 微生物による物質生産, 現代化学, 1月号, No.562, <特集>生命をつくる:ゲノム編集の時代, 36-41 (2018)
  2. 中村泰之, 伊藤洋一郎, 梅津光央, 石井純, 近藤昭彦, 低分子抗体医薬の開発展望, バイオインダストリー, Vol.34, No.6, 54-62 (2017)
  3. 蓮沼誠久, 石井純, 荻野千秋, 近藤昭彦, バイオリファイナリーの現状と展望, 化学と生物,Vol.53, No.10, 689-695 (2015)
  4. 石井純, 荒木通啓, 中津井雅彦, 崎濱由梨, 柘植陽太, 蓮沼誠久, 近藤昭彦, 合成生物工学によるモノづくり微生物のデザインに向けて, 生物工学会誌, 第93巻, 第9号, 523-526 (2015)
  5. 化学便覧 応用化学編 28章 バイオマス利用技術 
    28.1 近藤昭彦, 28.2.3 荻野千秋, 28.5.1 蓮沼誠久・近藤昭彦, 28.5.3 原清敬・近藤昭彦, 28.6.2 岡井直子・近藤昭彦, 28.6.3 石井純・近藤昭彦, 28.6.6 山田亮祐・近藤昭彦, 丸善出版, 1615-1651 (2014)
  6. 石井純,蓮沼誠久,松田史生, 近藤昭彦, バイオリファイナリー社会に向けた燃料・化学品生産, 安全工学, Vol.52, No.4, 249-255 (2013)
  7. 石井純,蓮沼誠久,松田史生, 近藤昭彦, 革新的なものづくり実現のための「合成生物工学」,生物工学会誌,91(6), 314-318 (2013)
  8. 石井純,荻野千秋,近藤昭彦, 次世代医薬開発に向けた抗体工学の最前線,第Ⅱ編第4章第4節,酵母による抗体フラグメントおよび抗体様結合性タンパク質の改変技術,シーエムシー出版, 60-65 (2012)
  9. 石井純, 田中勉, 荻野千秋, 近藤昭彦, シングルセル解析の最前線, 第3章4, フローサイトメトリーとGFPレポーターによるG蛋白質シグナルのシングルセル解析, シーエムシー出版, 158-165(2010)
  10. 石井純,田中勉,近藤昭彦,タンパク質間相互作用とシグナル伝達解析,未来材料 6. 40-45 (2007)
  11. 石井純,近藤昭彦, コンビナトリアル・バイオエンジニアリングによる新しい創薬システム, 生物工学会誌,84(8),319-321 (2006)