メンバー紹介

特命教授田口 精一 Seiichi Taguchi

経歴

1985/03
東京理科大学 理学部 応用化学科 卒業
1987/03
東京大学 大学院工学系研究科 工業化学専攻 前期修士課程 修了
1989/03
東京大学 大学院工学系研究科 工業化学専攻 後期博士課程 単位修得退学
1989/04
東京理科大学 基礎工学部 生物工学科 助手(1999年3月まで)
1997/01
仏国 ルイパスツール大学 分子細胞生物学研究所 客員研究員(1997年4月まで)
1999/04
理化学研究所 高分子化学研究室 先任研究員(2002年3月まで)
2000/04
マレーシア科学大学 客員教授(兼任)(2002年3月まで)
2002/04
明治大学 農学部 農芸化学科 助教授(2004年3月まで)
理化学研究所客員研究員(兼任)(2004年3月まで)
2004/04
北海道大学 大学院工学研究科 教授(2010年3月まで)
理化学研究所 客員主管研究員(兼任)
2010/04
北海道大学 大学院工学研究院 教授(2017年3月まで)
2017/04
北海道大学 大学院工学研究院 名誉教授
東京農業大学 生命科学部 教授
2022/01
神戸大学 大学院科学技術イノベーション研究科 客員教授
2022/04
神戸大学 大学院科学技術イノベーション研究科 特命教授<
神戸大学 先端バイオ工学研究センター 兼務

受賞等

  • 2016/04 平成28年度 科学技術分野の文部科学大臣表彰科学技術賞(研究部門)
  • 2014/03 北海道大学研究総長賞
  • 2004/06 バイオインダストリー協会 「発酵と代謝」研究奨励賞
  • 2002/06 天野エンザイム株式会社 酵素応用研究奨励賞
  • 2002/03 日本農芸化学会 第3回日本農芸化学会研究企画賞
  • 1992/06 日本放線菌学会研究奨励賞(浜田賞)

発表論文

  1. Koh, S., Saito, Y., Kudo, H., Taguchi, S., Kumagai, A., Mizuno, M., Samejima, M., Amano, Y. (2024/09) Synthesis of a natural core substrate with lignin-xylan cross-linkage for unveiling the productive kinetic parameters of glucuronoyl esterase, Biochemical Biophysical Research Communications, 734, 150642
  2. Koh, S., Sato, M., Matsusaki, H., Taguchi, S. (2024/09) The Discovery of Membrane Vesicle Biogenesis in the Polyhydroxybutyrate-non- producing Mutant Strain of Cupriavidus necator H16, Microbes and Environments, 39(3), ME24007
  3. Koh, S., Endo, R., Kahar, P., Mori, Y., Ogino, C., Tanaka, S., Tanaka, S., Imai, Y., Taguchi, S. (2024/08) Complete sequence randomness of lactate-based copolymers (LAHBs) with varied lactate monomer fractions employing a series of propionyl-CoA transferases., International Journal of Biological Macromolecules, 274, 133055
  4. Imai, Y., Tominaga, Y., Tanaka, S., Yoshida, M., Furutate, S., Sato, S., Koh, S., Taguchi, S. (2024/05) Modification of poly(lactate) via polymer blending with microbially produced poly[(R)-lactate-co-(R)-3-hydroxybutyrate] copolymers, International Journal of Biological Macromolecules, 266, 130990
    プレスリリース
  5. Koh, S., Furutate, S., Imai, Y., Kanda, T., Tanaka, S., Tominaga, Y., Sato, S., Taguchi, S. (2024/04) Microbial platform for tailor-made production of a biodegradable polylactide modifier: Ultrahigh-molecular-weight lactate-based polyester LAHB, ACS Sustainable Chem. Eng., 12, 6145-6156
    プレスリリース
  6. Koh, S., Noda, S., Taguchi, S. (2023) Population dynamics in the biogenesis of single-/multi-layered membrane vesicles revealed by encapsulated GFP-monitoring analysis. Appl. Microbiol., 3(3), 1027-1036
  7. Nagao, Y., Koh, S., Taguchi, S., Shimada, T. (2023) Cell-growth phase-dependent promotor replacement approach for improved poly(lactate-co-3-hydroxybutyrate) production in Escherichia coli. Microb. Cell Fact. 22, 131
  8. Koh, S., Sato, M., Yamashina, K., Usukura, Y., Toyofuku, M., Nomura, N., Taguchi, S. (2022) Controllable secretion of multilayer vesicles driven by microbial polymer accumulation, Scientific Reports, 12, 3393
  9. K. Yokoyama, D. Ogaya, H. Utsumi, M. Suzuki, T. Kashiwagi, E. Suzuki, S. Taguchi, (2021) Effect of introducing a disulfide bridge on the thermostability of microbial transglutaminase from Streptomyces mobaraensis, Applied and Environmental Microbiology, 105(7), 2737-2745
  10. S. Mizuno, T. Sakurai, M. Nabasama, K. Kawakami, A. Hiroe, S. Taguchi, T. Tsuge, (2021) The influence of medium composition on the microbial secretory production of hydroxyalkanoate oligomers, The Journal of General and Applied Microbiology, 67(4), 134-141
  11. A. Hiroe, T. Sakurai, S. Mizuno, Y. Miyahara, S. Goto, M. Yamada, T. Tsuge, S. Taguchi, (2021) Microbial oversecretion of (R)-3-hydroxybutyrate oligomer with diethylene glycol terminal as a macromonomer for polyurethane synthesis, Internationa of Journal of Biological Macromolecules, 167, 1290-1296
  12. T. Yajima, M. Nagatomo, A. Wakabayashi, M. Sato, S. Taguchi, M. Maeda, (2020) Bioconversion of biphenyl to a polyhydroxyalkanoate copolymer by Alcaligeneses denitrificans A41, AMB Express, 10, 155
  13. C. Hori, T. Sugiyama, K. Watanabe, J. Sun, Y. Kamada, T. Ooi, T. Isono, T. Satoh, S. Sato, S. Taguchi, K. Matsumoto, (2020) Isolation of poly[d-lactate (LA)-co-3-hydroxybutyrate)]-degrading bacteria from soil and characterization of d-LA homo-oligomer degradation by the isolated strain, 179, Polymer Degradation and Stability, 176
  14. R. Kadoya, N. Tanaka, Y. Shiwa, N. Fujita, S. Taguchi, (2020) Changed bacterial community in the river water samples upon introduction of biodegradable poly(3-hydroxybutyrate), Polymer Degradation and Stability, 176
  15. Y. Miyahara, A. Hiroe, T. Tsuge, S. Taguchi, (2019) Microbial secretion platform for 3-hydroxubutyrate oligomer and its end-capped forms using chain transfer reaction-mediated polyhydroxyalkanoate synthases, Biotechnology Journal, 14(12): e1900201
  16. K. Matsumoto, J. Saito, T. Yokoo, C. Hori, A. Nagata, Y. Kudoh, T. Ooi, S. Taguchi, (2019) Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO)-mediated de novo synthesis of glycolate-based polyhydroxyalkanoate in Escherichia coli, Journal of Bioscience and Bioengineering, 128(3), 302-306
  17. S. Goto, A. Hokamura, H. Shiratsuchi, S. Taguchi, K. Matsumoto, H. Abe, K. Tanaka, H. Matsusaki, (2019) Biosynthesis of novel lactate-based polymers containing medium-chain-length 3-hydroxyalkanoates by recombinant Escherichia coli strains from glucose, Journal of Bioscience and Bioengineering, 128(2), 191-197
  18. S. Goto, N. Suzuki, K. Matsumoto, S. Taguchi, Tanaka, H. Matsusaki, (2019) Enhancement of lactate fraction in poly(lactate-co-3-hydroxybutyrate) synthesized by Escherichia coli harboring the D-lactate dehydrogenase gene from Lactobacillus acetotolerans HT, The Journal of General and Applied Microbiology, 65(4), 204-208
  19. C. Utsunomia, S. Taguchi, (2018) Microbial secretion system of lactate-based oligomers and its application: Biosynthesis, Green Polymer Chemistry: New products, Processes, and Applications, Chapter 4, ACS Symposium Series, 1310, 41-60
  20. C. Hori, K. T. Yamazaki, G. Ribordy, K. Takisawa, K. Matsumoto, T. Ooi, M. Zinn, S. Taguchi, (2018) High-cell density culture of poly(lactate-co-3-hydroxybutyrate)-produing Escherichia coli by using glucose/xylose-switching fed-batch jar fermentation, Journal of Bioscience and Bioengineering, 127(6), 721-725
  21. M. Takenoyama, S. Taguchi, S. Yajima, (2018) Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum, Acta crystallographica Section F Structural Biology Communications, 74(Pt 11), 733-740
  22. K. Matsumoto, C. Hori, R. Fujii, M. Takaya, T. Ooba, T. Ooi, T. Isono, T. Satoh, S. Taguchi, (2018) In vitro analysis of d-lactyl-CoA-polymerizing polyhydoxyalkanoate synthase in polylactate and poly(lactate-co-3-hydroxybutyrate) synthases, Biomacromolecules, 19(7), 2889-2895
  23. K. Matsumoto, C. Hori, R. Fujii, M. Takaya, T. Ooba, T. Ooi, T. Isono, T. Satoh, S. Taguchi, (2018) Dynamic changes of intracellular monomer levels regulate block sequence of polyhydroxyalkanoates in engineered Escherichia coli, Biomacromolecules, 19(2), 662-672
  24. C. Hori, K. Oishi, K. Matsumoto, S. Taguchi: R. Kadoya, K. Matsumoto, K. Takisawa, T. Ooi, S. Taguchi, (2018) Site-directed saturation mutagenesis of polyhydroxyalkanoate synthase for efficient microbial production of poly[(R)-2-hydroxybutyrate], Journal of Bioscience and Bioengineering, 125(6), 632-636
  25. R. Kadoya, K. Matsumoto, K. Takisawa, T. Ooi, S. Taguchi, (2018) Enhanced production of lactate-based polyesters in Escherichia coli from a mixture of glucose and xylose by Mlc-mediated catabolite derepression, Journal of Bioscience and Bioengineering, 125(4), 365-370
  26. R. Kadoya, K. Matsumoto, K. Takisawa, T. Ooi, S. Taguchi, (2018) Enhanced production of lactate-based polyesters in Escherichia coli from a mixture of glucose and xylose by Mlc-mediated catabolite derepression, Journal of Bioscience and Bioengineering, 125(4), 365-370
  27. K. Matsumoto, K. Yamazaki, S. Kawakami, D. Miyoshi, T. Ooi, S. Hashimoto, S. Taguchi, (2017) In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay), Scientific Reports, 7(1): 12136
  28. C. Utsunomia, T. Saito, K. Matsumoto, C. Hori, T. Isono, T. Satoh, S. Taguchi, (2017) Synthesis of lactate(LA)-based poly(ester-urethane) using hydroxyl-terminated LA-based oligomers from a microbial secretion system, Journal of Polymer Research, 24(10), 167-171
  29. C. Utsunomia, C. Hori, K. Matsumoto, S. Taguchi, (2017) Investigation of the Escherichia coli membrane transporters involved in the secretion of D-lactate-based oligomers by loss-of-function screening, Journal of Bioscience and Bioengineering, 124(2), 635-640
  30. C. Utsunomia, K. Matsumoto, K. Date, C. Hori, S. Taguchi, (2017) Microbial secretion of lactate-enriched oligomers for efficient conversion into lactide: A biological shortcut to polylactide, Journal of Bioscience and Bioengineering, 124(2), 204-208
  31. C. Utsunomia, K. Matsumoto, S. Taguchi, (2017) Microbial secretion of D-lactate-based oligomers, ACS Sustainable Chemistry & Engineering, 5(3), 2360-2367
  32. K. Matsumoto, T. Shiba, Y. Hiraide, S. Taguchi, (2017) Incorporation of glycolate units promotes hydrolytic degradation in flexible poly(glycolate-co-3-hydroxybutyrate) synthesized by engineered Escherichia coli, ACS Biomaterials Science & Engineering, 3(12), 3058-3063
  33. D. Ishii, K. Takisawa, K. Matsumoto, T. Ooi, T. Hikima, M. Takata, S. Taguchi, T. Iwata, (2017) Effect of monomeric composition on the thermal, mechanical and crystalline properties of poly[(R)-lactate-co-(R)-3-hydroxybutyrate], Polymer, 122, 169-173
  34. L. Salamanca-Cardona, R.A. Scheel, K. Mizuno, N.S. Bergey, A.J. Stipanovic, K. Matsumoto, S. Taguchi, C.T. Nomura, (2017) Effect of acetate as a co-feedstock on the production of poly(lactate-co-3-hydroxyalkanoate) by pflA-deficient Escherichia coli, Journal of Bioscience and Bioengineering, 123, 547-554
  35. R. Kadoya, Y. Kodama, K. Matsumoto, T. Ooi, S. Taguchi, (2017) Genome-wide screening of transcription factor deletion targets in Escherichia coli for enhanced production of lactate-based polyesters, Journal of Bioscience and Bioengineering, 123(5), 535-539
  36. K. Takisawa, T. Ooi, K. Matsumoto, R. Kadoya, S. Taguchi, (2017) Xylose-based hydrolysate from eucalyptus extract as feedstock for poly(lactate-co-3-hydroxybutyrate) production in engineered Escherichia coli, Process Biochemistry, 54, 102-105
  37. T. Yoshizumi, M. Yamada, M. Higuchi-Takeuchi, K. Matsumoto, S. Taguchi, M. Matsui, K. Numata, (2017) Polyhydroxyalkanoate accumulation in Arabidopsis does not inhibit plant growth, Plant Biotechnology, 34(1), 39-43
  38. S. Taguchi, (2017) Designer enzyme for materials innovation: Lactate-polymerizing enzyme as a key catalyst, Frontiers of Chemical Science and Engineering, 11, 139-142
  39. K. Tajima, X. Han, Y. Hashimoto, Y. Satoh, T. Satoh, S. Taguchi, (2016) In vitro synthesis of polyhydroxyalkanoate using thermostable acetyl-CoA syntase, CoA transferase, and PHA synthase from thermotorelant bacteria, Journal of Bioscience and Bioengineering, 122, 660-665
  40. T. Kabe, K. Matsumoto, S. Terai, T. Hikima, M. Takata, M. Miyake, S. Taguchi, T. Iwata, (2016) Co-crystallization phenomena in biosynthesized isotactic poly[(R)-lactate-co-(R)-2-hydroxybutyrate]s with various lactate unit ratios, Polymer Degradation and Stability, 132, 137-144
  41. L. Salamanca-Cordona, R. Scheel, N. BergeyY, A. Stipanovic C, K. Matsumoto, S. Taguchi, C. Nomura, (2016) Consolidated bioprocessing of poly(lactate-co-3-hydroxybutyrate) from xylan as a sole feedstock by genetically-engineered Escherichia coli, Journal of Bioscience and Bioengineering, 122, 406-414
  42. J. Sun, C. Utsunomia, S. Sasaki, K. Matsumoto, T. Yamada, T. Ooi, S. Taguchi, (2016) Microbial production of poly(lactate-co-3-hydroxybutyrate) from hybrid Miscanthus-derived sugars, Bioscience, Biotechnology, and Biochemistry, 80, 818-820
  43. J. Sun, K. Matsumoto, Y. Tabata, R. Kadoya, T. Ooi, H. Abe, S. Taguchi, (2015) Molecular weight-dependent degradation of D-lactate-containing polyesters by polyhydroxyalkanoate depolymerases from Variovorax sp. C34 and Alcaligenes faecalis T1, Applied and Environmental Microbiology, 99, 9555-9563
  44. R. Kadoya, Y. Kodama, K. Matsumoto, S. Taguchi, (2015) Indirect positive effects of a sigma factor RpoN deletion on the lactate-based polymer production in Escherichia coli, Bioengineered, 6: 307-311
  45. R. Kadoya, K. Matsumoto, T Ooi, S. Taguchi, (2015) MtgA deletion-triggered cell enlargement of Escherichia coli for enhanced intracellular polyester accumulation, PLos ONE, 10, e0125163
  46. R. Kadoya, Y. Kodama, K. Matsumoto, S. Taguchi, (2015) Enhanced cellular content and lactate fraction of the P(lactate-co-3-hydroxybutyrate) produced in recombinant Escherichia coli by the deletion of sigma factor RpoN, Journal of Bioscience and Bioengineering, 119, 427-429
  47. T. Yokoo, K. Matsumoto*, T. Ooba, K. Morimoto, S. Taguchi, (2015) Enhanced poly(3-hydroxybutyrate) production in transgenic tobacco BY-2 cells using engineered acetoacetyl-CoA reductase, Bioscience, Biotechnology, and Biochemistry, 3, 1-3
  48. J. Sun, K. Matsumoto, J. M. Nduko, T. Ooi, S. Taguchi, (2014) Enzymatic characterization of a depolymerase from the isolated bacterium Variovorax sp. C34 that degrades poly(enriched lactate-co-3-hydroxybutyrate), Polymer Degradation and Stability, 110, 44-49
  49. K. Matsumoto, K. Tobitani, S. Aoki, Y. Song, T. Ooi, S. Taguchi, (2014) Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step, AMB Express, 4, 83
  50. L. Salamanca-Cardona, R. A. Scheel, B. R. Lundgren, A. J. StipanovicC, K. Matsumoto, S. Taguchi, C. T. Nomura, (2014) Deletion of the pflA gene in Escherichia coli LS5218 and its effects on the production of polyhydroxyalkanoates using beechwood xylan as a feedstock, Bioengineered, 5, 284-287
  51. R. Tappel, W. Pan, N Bergey, Q. Wang, I Patterson, O. Ozumba, K. Matsumoto, S. Taguchi, C. Nomura, (2014) Engineering Escherichia coli for improved production of short-chain-length-co-medium-chain-length poly[(R)-3-hydroxyalkanoate] (SCL-co-MCL PHA) copolymers from renewable non-fatty acid feedstocks, ACS Sustainable Chemistry & Engineering, 2(7), 1879-1887
  52. J. M. Nduko, K. Matsumoto, T. Ooi, S. Taguchi, (2014) Enhanced production of poly(lactate-co-3-hydroxybutyrate) from xylose in engineered Escherichia coli overexpressing a galactitol transporter, Applied and Environmental Microbiology, 98, 2453-2460
  53. J. Yu, D. Ogata, Z. Gai, S. Taguchi, I. Tatanka, T. Ooi, M. Yao, (2014) Structure of AzrA, AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism, Acta Crystallographica Section D, 70, 553-564
  54. K. Matsumoto, Y. Tanaka, T. Watanabe, R. Motohashi, K. Ikeda, K. Tobitani, M. Yao, I. Tanaka, S. Taguchi, (2013) Directed evolution and structural analysis of NADPH-dependent acetoacetyl-CoA reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics, Applied and Environmental Microbiology, 79(19), 6134-6139
  55. J. M. Nduko, K. Matsumoto, S. Taguchi, (2013) Chapter 13 Microbial plastic factory: Synthesis and properties of the new lactate-based biopolymers, Green Polymer Chemistry: Biocatalysis and Materials II, ACS Symposium Series, 1144, American Chemical Society, 175-197/447
  56. K. Matsumoto, S. Terai, A. Ishiyama, J. Sun, T. Kabe, Y. Song, J. M. Nduko, T. Iwata, S. Taguchi, (2013) One-pot microbial production, mechanical properties and enzymatic degradation of isotactic P[(R)-2-hydroxybutyrate] and its copolymer with (R)-lactate, Biomacromolecules, 14(6), 1913-1918
  57. A. Ochi, K. Matsumoto, T. Ohba, K. Sakai, T. Tsuge, S. Taguchi, (2013) Engineering of class I lactate-polymerizing polyhydroxyalkanoate synthases from Ralstonia eutropha that synthesize lactate-based polyester with a block nature, Applied and Environmental Microbiology, 97(8), 3441-3447
  58. J. M. Nduko, K. Matsumoto, T. Ooi, S. Taguchi, (2013) Effectiveness of xylose utilization for high yield production of lactate-enriched P(lactate-co-3-hydroxybutyrate) using a lactate-overproducing strain of Escherichia coli and an evolved lactate-polymerizing enzyme, Metabolic Engineering, 15, 159-166
  59. Y. Song, K. Matsumoto, T. Tanaka, A. Kodoh, S. Taguchi, (2012) Single-step production of polyhydroxybutyrate from starch by using α-amylase cell-surface displaying system of Corynebacterium glutamicum, Journal of Bioscience and Bioengineering, 115(1), 12-14
  60. J.-A. Chuah, M. Yamada, S. Taguchi, S. Kumar, Y. Doi, K. Numata, (2013) Biosynthesis and characterization of polyhydroxyalkanoate containing 5-hydroxyvalerate (5HV) units: Effects of 5HV units on biodegradability, cytotoxicity, mechanical and thermal properties, Polymer Degradation and Stability, 98, 331-338
  61. K. Matsumoto, T. Okey, I. Honma, T. Ooi, H. Aoki, S. Taguchi, (2012) Efficient (R)-3-hydroxybutyrate production using acetyl-CoA regenerating pathway catalyzed by coenzyme A transferase, Applied and Environmental Microbiology, 97, 205-210
  62. J. M. Nduko, K. Matsumoto, S. Taguchi, (2012) Biological lactate-polymers synthesized by one-pot microbial factory: Enzyme and metabolic engineering, Biobased Monomers, Polymers, and Materials, ACS Symposium Series, American Chemical Society, 1105, 215-235/360
  63. K. Tajima, X. Han, Y. Satoh, A. Ishii, Y. Araki, M. Munekata, S. Taguchi, (2012) In vitro synthesis of polyhydroxyalokanoate (PHA) incorporating lactate (LA) with a block sequence by using a newly engineered thermostable Pseudomonas sp. SG4502 PHA synthase with acquired LA-polymerizing activity, Applied and Environmental Microbiology, 94, 365-376
  64. Y. Song, K. Matsumoto, M. Yamada, A. Gohda, C. J. Brigham, A. J. Sinsky, S. Taguchi, (2012) Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production, Applied and Environmental Microbiology, 93(5), 1919-1925
  65. Y. Watanabe, Y. Ichinomiya, D. Shimada, A. Saika, H. Abe, S. Taguchi, T. Tsuge, (2012) Development and validation of an HPLC-based screening method to require polyhydroxyalkanoate synthase mutants with altered substrate specificity, Journal of Bioscience and Bioengineering, 113, 286-292
  66. T. Ooi, D. Ogata, K. Matsumoto, G. Nakamura, J. Yu, Y. Min, M. Kitamura, S. Taguchi, (2012) Flavin-binding of azoreductase: Direct evidences for dual-binding property of apo-azoreductase with FMN and FAD, Journal of Molecular Catalysis B, 74, 204-208
  67. A. Ochi, K. Matsumoto, T. Ooba, K. Sakai, T. Tsuge, S. Taguchi, (2012) Engineering of class 1 lactate polymerizing polyhydroxyalkanoate synthase from Ralstonia eitropha that synthesize lactate-based polyester with a block nature, Applied and Environmental Microbiology, 97, 3441-2447
  68. J. M. Nduko, W. Suzuki, K. Matsumoto, H. Kobayashi, T. Ooi, A. Fukuoka, S. Taguchi, (2011) Polyhydroxyalkanoates production from cellulose hydrolysate in Escherichia coli LS5218 with superior resistance against 5-hydroxymethylfurfural, Journal of Bioscience and Bioengineering, 113, 70-72
  69. K. Matsumoto, A. Ishiyama, K. Sakai, T. Shiba, S. Taguchi, (2011) Biosynthesis of glycolate-based polyesters containing medium-chain-length 3-hydroxyalkanoates in recombinant Escherichia coli expressing engineered polyhydroxyalkanoate synthase, Journal of Biotechnology, 156, 214-217
  70. X. Han, Y. Satoh, T. Satoh, K. Matsumoto, T. Kakuchi, S. Taguchi, T. Dairi, M. Munekata, K. Tajima, (2011) Chemo-enzymatic synthesis of polyhydroxyalkanoate (PHA) incorporating 2-hydroxybutyrate by wild-type class I PHA synthase from Ralstonia eutropha, Applied and Environmental Microbiology, 92, 509-517
  71. M. Yamada, K. Matsumoto, S. Uramoto, R. Motohashi, H. Abe, S. Taguchi, (2011) Lactate fraction dependent mechanical properties of semitransparent poly(lactate-co-3-hydroxybutyrate)s produced by control of lactyl-CoA monomer fluxes in recombinant Escherichia coli, Journal of Biotechnology, 154, 255-260
  72. K. Buhbalan, J-A. Chuah, F. Shozui, S. Taguchi, C. J. Brigham, A. J. Sinsky, K. K. Sudesh, (2011) Characterization of the highly active PHA synthase of Chromobacterium sp. USM2, Applied and Environmental Microbiology, 77, 2926-2933
  73. K. Matsumoto, K. Morimoto, A. Gohda, H. Shimada, S. Taguchi, (2011) Improved polyhydroxybutyrate (PHB) production in transgenic tobacco by enhancing translation efficiency of bacterial PHB biosynthetic genes, Journal of Bioscience and Bioengineering, 111, 485-488
  74. K. Matsumoto, K. Kitagawa, S-J, Jo, Y. Song, S. Taguchi, (2011) Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Corynebacterium glutamicum using propionate as a precursor, Journal of Biotechnology, 152, 144-146
  75. K. Matsumoto, M. Yamada, C. R. Leong, S. J. Jo, T. Kuzuyama, S. Taguchi, (2011) A new pathway for poly(3-hydroxybutyrate) production in Escherichia coli and Corynebacterium glutamicum by functional expression of a new acetoacetyl-coenzyme A synthase, Bioscience, Biotechnology, and Biochemistry, 75, 364-366
  76. F. Shozui, K. Matsumoto, R. Motohashi, J. Sun, S. Taguchi, (2011) Biosynthesis of lactate(LA)-based polyester with a 96 mol% LA fraction and its application to stereocomplex formation, Polymer Degradation and Stability, 96, 499-504
  77. K. Matsumoto, H. Kobayashi, K. Ikeda, T. Komanoya, A. Fukuoka, S. Taguchi, (2011) Chemo-microbial conversion of cellulose into polyhydroxybutyrate through ruthenium-catalyzed hydrolysis of cellulose into glucose, Bioresource Technology, 102, 3564-3567
  78. J. Sun, F. Shozui, M. Yamada, K. Matsumoto, S. Taguchi, (2010) Production of P(3-hydroxybutyrate-co-3-hydroxyhexanoate-co-3-hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida, Bioscience, Biotechnology, and Biochemistry, 74, 1716-1718
  79. F. Shozui, J. Sun Y. Song, M. Yamada, K. Sakai, K. Matsumoto, K. Takase, S. Taguchi, (2010) A new beneficial mutation in Pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template, Bioscience, Biotechnology, and Biochemistry, 74, 1710-1712
  80. K. Yokoyama, H. Utsumi, T. Nakamura, D. Ogaya, N. Shimba, E. Suzuki, S. Taguchi, (2010) Screening for improved activity of a transglutaminase from Streptomyces mobaraensis created by a novel rational mutagenesis and random mutagenesis, Applied and Environmental Microbiology, 87, 2087-2096
  81. F. Shozui, K. Matsumoto, R. Motohashi, M. Yamada, S. Taguchi, (2010) Establishment of a metabolic pathway to introduce the 3-hydroxyhexanoate unit into LA-based polyesters via a reverse reaction of β-oxidation in Escherichia coli LS5218, Polymer Degradation and Stability, 95, 1340-1344
  82. T. Imamura, M. Yasuda, H. Kusano, H. Nakashita, Y. Ohno, T. Kamakura, S. Taguchi, H. Shimada, (2010) Acquired resistance to the rice blast in transgenic rice accumulating the antimicrobial peptide thanatin, Transgenic Researchearch, 19, 415-424
  83. Q. Wang, A. Mueller, R. L. Chean, K. Matsumoto, S. Taguchi, C. T. Nomura, (2010) Quick and efficient method for genetic transformation of biopolymer producing bacteria, Journal of Chemical Technology and Biotechnology, 85, 775-778
  84. D. Ogata, T. Ooi, T. Fujikawa, S. Taguchi, I. Tanaka, M. Yao, (2010) Crystallization and preliminary X-ray studies of azoreductases from Bacillus sp. B29, Acta Crystallographica section F, 66, 503-505
  85. K. Matsumoto, Y. Orakasa, K. Ichinohe, S. Hashimoto, T. Ooi, S. Taguchi, (2010) Flow cytometric analysis of the contributing factors for antimicrobial activity enhancement of cell-penetrating type peptides: case study on engineered apidaecins, Biochemical and Biophysical Research Communications, 395, 7-10
  86. K. Matsumoto, Y. Mukai, D. Ogata, F. Shozui, J. M. Nduko, S. Taguchi, T. Ooi, (2010) Characterization of thermostable FMN-dependent NADH azoreductase from the moderate thermophile Geobacillus stearothermophilus, Applied and Environmental Microbiology, 86, 1431-1438
  87. M. Yamada, K. Matsumoto, K. Shimizu, S. Uramoto, T. Nakai, F. Shozui, S. Taguchi, (2010) Adjustable mutations in lactate (LA)-polymerizing enzyme for the microbial production of LA-based polyesters with tailor-made monomer composition, Biomacromolecules, 11, 815-819
  88. F. Shozui, K. Matsumoto, T. Nakai, M. Yamada, S. Taguchi, (2010) Biosynthesis of novel terpolymers poly(lactate-co-3-hydroxybutyrate-co-3-hydroxyvalerate) in lactate-overproducing mutant Escherichia coli JW0885 by feeding propionate as a precursor of 3-hydroxyvalerate, Applied and Environmental Microbiology, 85, 949-954
  89. F. Shozui, K. Matsumoto, T. Sasaki, S. Taguchi, (2009) Engineering of polyhydroxyalkanoate synthase by Ser477X/Gln481X saturation mutagenesis for efficient production of 3-hydroxybutyrate-based copolyesters, Applied and Environmental Microbiology, 84, 1117-1124
  90. T. Ooi, H. Sato, K. Matsumoto, S. Taguchi, (2009) A unique post-translational processing of an exo-b-glucanase of Penicillium sp. KH10 expressed in Aspergillus oryzae, Protein Expression and Purification, 67, 126-131
  91. Y. Orikasa, K. Ichinohe, J. Saito, S. Hashimoto, K. Matsumoto, T. Ooi, S. Taguchi, (2009) Hydrophobicity in chemically modified side-cahin of cysteine residues of thanatin is related to antimicrobial activity against Micrococcus luteus, Bioscience, Biotechnology, and Biochemistry, 73, 1683-1684
  92. T. Ooi, T. Shibata, K. Matsumoto, S. Kinoshita, S. Taguchi, (2009) Comparative enzymatic analysis of azoreductases from Bacillus sp. B29, Bioscience, Biotechnology, and Biochemistry, 73, 1209-1211
  93. S. J. Jo, C. R. Leong, K. Matsumoto, S. Taguchi, (2009) Dual production of poly(3-hydroxybutyrate) with glutamate using Corynebacterium glutamicum by regulation of biotin concentration, Journal of Bioscience and Bioengineering, 107, 409-411
  94. K. Matsumoto, T. Murata, R. Nagao, C. Nomura, S. Arai, K. Takase, H. Nakashita, S. Taguchi, H. Shimada, (2009) Production of short-chain-length/medium-chain-length polyhydroxyalkanoate (PHA) copolymer in the plastid of Arabidopsis thaliana using the evolved 3-ketoacyl-acyl carrier protein synthase III, Biomacromolecules, 10, 686-690
  95. K. Matsumoto, K. Takase, Y. Yamamoto, Y. Doi, S. Taguchi, (2009) Chimeric enzyme composed of polyhydroxyalkanoate (PHA) synthases from Ralstonia eutropha and Aeromonas caviae enhances production of PHAs in recombinant Escherichia coli, Biomacromolecules, 10, 682-685
  96. M. Yamada, K. Matsumoto, T. Nakai, S. Taguchi, (2009) Microbial production of lactate-enriched poly[(R)-lactate-co-(R)-3-hydroxybutyrate] with novel thermal properties, Biomacromolecules, 10, 677-681
  97. K. Tajima, Y. Satoh, T. Satoh, R. Itoh, X. Han, S. Taguchi, T. Kakuchi, M. Munekata, (2009) Chemo-enzymatic synthesis of poly(lactate-co-(3-hydroxybutyrate)) by a lactate-polymerizing enzyme, Macromolecules, 42, 1985-1989
  98. K. Matsumoto, F. Shozui, Y. Satoh, K. Tajima, M. Munekata, S. Taguchi, (2009) Kinetic analysis of engineered polyhydroxyalkanoates synthases with broad substrate specificity, Polymer Journal, 41, 237-240
  99. S. Taguchi, K. Mita, K. Ichinohe, S. Hashimoto, (2009) Targeted engineering of the antibacterial peptide, apidaecin, based on an in vivo monitoring assay system, Applied and Environmental Microbiology, 75, 1460-1464
  100. T. Tsuge, T. Yamamoto, K. Yana, H. Abe, Y. Doi, S. Taguchi, (2009) Evaluating the ability of polyhydroxyalkanoate synthase mutants to produce P(3HB-co-3HA) from soybean oil, Macromolecular Bioscience, 9, 71-78
  101. K. Tajima, Y. Satoh, T. Satoh, R. Itoh, X. Han, S. Taguchi, T. Kakuchi, M. Munekata, (2009) Chemo-enzymatic synthesis of poly (lactate-co-(3-hydroxybutyrate)) by a lactate-polymerizing enzyme, Macromolecules, 42, 1985-1989
  102. S. Taguchi, M. Yamada, K. Matsumoto, K. Tajima, Y. Sato, M. Munekata, K. Ohono, K. Kohda, T. Shimamura, H. Kambe, S. Obata, (2008) A microbial factory for lactate-based polyesters using a lactate-polymerizing enzyme, Proceedings of the National Academy of Sciences of USA, 105(45), 17323-17327
  103. K. Kuwasako, N. Dohme, M. Inoue, M. Shirouzu, S. Taguchi, P. Guntert, B. Seraphin, Y. Muto, S. Yokoyama, (2008) Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses, Proteins, 71, 1617-1636
  104. K. Kuwasako, M. Takahashi, N. Tochio, C. Abe, M. Inoue, T. Terada, M. Shirouzy, N. Kobayashi, T. Kigawa, S. Taguchi, A. Tanaka, Y. Hayashizaki, P. Guntert, Y. Muto, S. Yokoyama, (2008) Solution structure of the second RNA recognition motif (RRM) domain of murine T cell intracellular antigen-1 (TIA-1) and its RNA recognition mode, Biochemistry, 47, 6437-6450
  105. C. T. Nomura, T. Tanaka, T. E. Eguen, A. S. Appah, K. Matsumoto, S. Taguchi, S, Ortiz CL, Y. Doi, (2008) FabG mediates polyhydroxyalkanoate production from both related and nonrelated carbon sources in recombinant Escherichia coli LS5218, Biotechnology Progress, 24, 342-351
  106. T. Imamura, N. Yamamoto, A. Tamura, S. Murabayashi, S. Hashimoto, H. Shimada, S. Taguchi, (2008) NMR based structure-activity relationship analysis of an antimicrobial peptide, thanatin, engineered by site-specific chemical modification: activity improvement and spectrum alteration, Biochemical and Biophysical Research Communications, 369, 609-615
  107. T. Tsuge, S. Watanabe, D. Shimada, H. Abe, Y. Doi, S. Taguchi, (2007) Combination of N149S and D171G mutations in Aeromonas caviae PHA synthase and impact on polyhydroxyalkanoate biosynthesis, FEMS Microbiology Letters, 277, 217-222
  108. S. J. Jo, K. Matsumoto, C. R. Leong, T. Ooi, S. Taguchi, (2007) Improvement of poly(3-hydroxybutyrate) [P(3HB)] production in Corynebacterium glutamicum by codon optimization, point mutation and gene dosage of P(3HB) biosynthetic genes, Journal of Bioscience and Bioengineering, 104, 457-463
  109. T. Tsuge, S. Watanabe, S. Sato, T. Hiraishi, H. Abe, Y. Doi, S. Taguchi, (2007) Variation in copolymer composition and molecular weight of polyhydroxyalkanoate generated by saturation mutagenesis of Aeromonas caviae PHA synthase, Macromolecular Bioscience, 7, 846-854
  110. S. J. Jo, K. Matsumoto, C. R. Leong, T. Ooi, S. Taguchi, (2007) Improvement of poly(3-hydroxybutyrate) [P(3HB)] production in Corynebacterium glutamicum by codon optimization, point mutation and gene dosage of P(3HB) biosynthetic genes, Journal of Bioscience and Bioengineering, 104, 457-463
  111. M. Yamada, A. Wakuda, S. Taguchi, (2007) Morphological change in cellular granule formation of poly[(R)-3-hydroxybutyrate] caused by DNA-binding-related mutations of an autoregulated repressor PhaR, Bioscience, Biotechnology, and Biochemistry, 71, 1572-1576
  112. C. T. Nomura, S. Taguchi, (2007) PHA synthase engineering toward superbiocatalysts for custom-made biopolymers, Applied and Environmental Microbiology, 73(5), 969-979
  113. H. Watanabe, K. Tsumoto, S. Taguchi, K. Yamashita, Y. Doi, Y. Nishiyama, H. Kondo, M. Umetsu, I. Kumagai, (2007) A human antibody fragment with high affinity for biodegradable polymer film, Bioconjugate Chemistry, 18, 645-651
  114. M. Yamada, K. Yamashita, A. Wakuda, K. Ichimura, A. Maehara, M. Maeda, S. Taguchi, (2007) Autoregulator protein PhaR for biosynthesis of polyhydroxybutyrate [P(3HB)] possibly has two separate domains that bind to the target DNA and P(3HB): functional mapping of amino acid residues responsible for DNA binding, Journal of Bacteriology, 189, 1118-1127
  115. T. Hiraishi, Y. Hirahara, Y. Doi, M. Maeda, S. Taguchi, (2006) Effects of mutations in the substrate-binding domain of poly[(R)-3-hydroxybutyrate] (PHB) depolymerase from Ralstonia pickettii T1 on PHB degradation, Applied and Environmental Microbiology, 72, 7331-7338
  116. K. Matsumoto, Y. Arai, R. Nagao, T. Murata, K. Takase, H. Nakashita, S. Taguchi, H. Shimada, Y. Doi, (2006) Synthesis of short-chain-length/medium-chain length polyhydroxyalkanoate (PHA) copolymers in peroxisome of the transgenic Arabidopsis thaliana harboring the PHA synthase gene from Pseudomonas sp. 61-3, Journal of Polymers and the Environment, 14, 369-374
  117. S. J. Jo, M. Maeda, T. Ooi, S. Taguchi, (2006) Production system for biodegradable polyester polyhydroxybutyrate by Corynebacterium glutamicum, Journal of Bioscience and Bioengineering, 102, 233-236
  118. K. Matsumoto, E. Aoki, K. Takase, Y. Doi, S. Taguchi, (2006) In vivo and in vitro characterization of Ser477X mutations in polyhydroxyalkanoate (PHA) synthase 1 from Pseudomonas sp. 61-3: Effects of beneficial mutations on enzymatic activity, substrate specificity, and molecular weight of PHA, Biomacromolecules, 7, 2436-2442
  119. K. Yamashita, M. Yamada, K. Numata, S. Taguchi, (2006) Nonspecific hydrophobic interactions of a repressor protein, PhaR, with poly[(R)-3-hydroxybutyrate] film studied with a quartz crystal microbalance, Biomacromolecules, 7, 2449-2454
  120. Y. M. Normi, T. Hiraishi, S. Taguchi, H. Abe, K. Sudesh, N. Najimudin, Y. Doi, (2005) Site-directed saturation mutagenesis of residue F420 and recombination of beneficial mutations of Ralstonia eutropha PHA synthase: Analysis of mutational effects on poly(3-hydroxybutyrate) and PHA synthase, Biotechnology Letters, 27, 705-712
  121. K. Matsumoto, R. Nagao, T. Murata, Y. Arai, T. Kichise, H. Nakashita, S. Taguchi, H. Shimada, Y. Doi, (2005) Enhancement of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) production in the recombinant Arabidopsis thaliana by the in vitro evolved highly active mutants of polyhydroxyalkanoate (PHA) synthase from Aeromonas caviae, Biomacromolecules, 6, 2126-2130
  122. Y. M. Normi, T. Hiraishi, S. Taguchi, H. Abe, K. Sudesh, N. Najimudin, Y. Doi, (2005) Characterization and properties of G4X mutants of Ralstonia eutropha PHA synthase for poly(3-hydroxybutyrate) biosynthesis in Escherichia coli, Macromolecular Bioscience, 5, 197-206
  123. T. Tsuge, K. Yano, S. Imazu, K. Numata, Y. Kikkawa, H. Abe, S. Taguchi, Y. Doi, (2005) Biosynthesis of polyhydoroxyalkanoate(PHA) copolymer from fructose using wild-type and laboratory-evolved PHA synthases, Macromolecular Bioscience, 5, 112-117
  124. K. Matsumoto, K. Takase, S. Taguchi, Y. Doi, (2005) Synergistic effects of Glu130Asp substitution in the type II polyhydroxyalkanoate (PHA) synthase: enhancement of PHA production and alteration of polymer molecular weight, Biomacromolecules, 6, 99-104
  125. K. Takase, K. Matsumoto, S. Taguchi, Y. Doi, (2004) Alteration of substrate chain-length specificity of type II synthase for polyhydroxyalkanoate biosynthesis by in vitro evolution: in vivo and in vitro enzyme assays, Biomacromolecules, 5, 480-485
  126. C. T. Nomura, K. Taguchi, S. Taguchi, Y. Doi, (2004) Coexpression of genetically engineered 3-ketoacyl-ACP synthase (fabH) and polyhydroxyalkanoate synthase (phaC) genes leads to short-chain-length-medium-chain-length polyhydroxyalkanoate copolymer production from glucose in Escherichia coli JM109, Applied and Environmental Microbiology, 70, 999-1007
  127. T. Tsuge, S. Imazu, K. Takase, S. Taguchi, Y. Doi, (2004) An extra large insertion in the polyhydroxyalkanoate synthase from Delftia acidovorans DS-17: its deletion effects and relation to cellular proteolysis, FEMS Microbiology Letters, 231, 77-83
  128. T. Tsuge, T. Hisano, S. Taguchi, Y. Doi, (2003) Alteration of chain length substrate specificity of Aeromonas cavie (R)-specific enoyl-CoA hydratase through site-directed mutagenesis, Applied and Environmental Microbiology, 16, 107-113
  129. Y. Suzuki, S. Taguchi, T. Hisano, K. Toshima, S. Matsumura, Y. Doi, (2003) Correlation between structure of the lactones and substrate specificity in enzyme-catalyzed polymerization for the synthesis of polyesters, Biomacromolecules, 4, 537-543
  130. S. Taguchi, H. Nakamura, T. Kichise, T. Tsuge, I. Yamato, Y. Doi, (2003) Production of polyhydroxyalkanoate (PHA) from renewable carbon sources in recombinant Ralstonia eutropha using mutants of original PHA synthase, Biochemical Engineering Journal, 16, 107-113
  131. K. Takase, S. Taguchi, Y. Doi, (2003) Enhanced synthesis of poly(3-hydroxybutyrate) in recombinant Escherichia coli by means of error-prone PCR mutagenesis, saturation mutagenesis and in vitro recombination of type II polyhydroxyalkanoate synthase gene, The Journal of Biochemistry, 133, 139-145
  132. T. Tsuge, K. Taguchi, S. Taguchi, Y. Doi, (2003) Molecular characterization and properties of (R)-specific enoyl-CoA hydratases from Pseudomonas aeruginosa: metabolic tools for synthesis of designed polyhydroxyalkanoate via fatty acid β-oxidation, International Journal of Biological Macromolecules, 31, 195-205
  133. S. Taguchi, K. Arakawa, K. Yokoyama, S. Takehana, H. Takagi, H. Momose, (2002) Overexpression and purification of microbial pro-transglutaminase from Streptomyces cinnamoneum and in vitro processing by Streptomyces albogriseolus proteases, Journal of Bioscience and Bioengineering, 94, 478-481
  134. S. Taguchi, H. Matsusaki, K. Matsumoto, K. Takase, K. Taguchi, Y. Doi, (2002) Biosynthesis of biodegradable copolyesters from renewable carbon sources by recombinant bacteria, Polymer International, 51, 899-906
  135. A. Maehara, S. Taguchi, T. Nishiyama, T. Yamane, Y. Doi, (2002) A repressor protein, PhaR, regulates PHA synthesis via its direct interaction with PHA, Journal of Bacteriology, 184, 3992-4002
  136. S. Taguchi, H. Nakamura, T. Hiraishi, I. Yamato, Y. Doi, (2002) In vitro evolution of a polyhydroxybutyrate synthase by intragenic suppression-type mutagenesis, The Journal of Biochemistry, 131, 801-806
  137. A. Arisawa, M. Matsufuji, T. Nakashima, K. Dobashi, K. Issiki, T. Yoshioka, S. Yamada, H. Momose, S. Taguchi, (2002) Streptomyces serine protease (DHP-A) as a new biocatalyst capable of forming chiral intermediates of 1,4-hydropyridine calcium antagonists, Applied and Environmental Microbiology, 68, 2716-2725
  138. T. Kichise, S. Taguchi, Y. Doi, (2002) Enhanced accumulation and changed monomer composition in polyhydroxyalkanoate (PHA) copolyester by in vitro evolution of Aeromonas caviae PHA polymerase, Applied and Environmental Microbiology, 68, 2411-2419
  139. Y. Suzuki, S. Taguchi, T. Saito, K. Toshima, S. Matsumura, Y. Doi, (2001) Involvement of catalytic amino acid residues in enzyme-catalyzed polymerization, Biomacromolecules, 2, 541-544
  140. S. Taguchi, A. Maehara, K. Takase, M. Nakahara, H. Nakamura, Y. Doi, (2001) Analysis of mutational effects of a polyhydroxybutyrate (PHB) polymerase on bacterial PHB accumulation using an in vivo assay system, FEMS Microbiology Letters, 198, 65-71
  141. K. Matsumoto, H. Matsusaki, S. Taguchi, M. Seki, Y. Doi, (2001) Cloning and characterization of the Pseudomonas sp. 61-3 phaG gene involved in polyhydroxyalkanoate biosysnthesis, Biomacromolecules, 2, 142-147
  142. S. Taguchi, K. Kuwasako, A. Suenaga, M. Okada, H. Momose, (2000) Functional mapping against Escherichia coli for the broad spectrum antimicrobial peptide, thanatin, based on the in vivo monitoring assay system, The Journal of Biochemistry, 128, 745-754
  143. S. Taguchi, K. Nishihama, K. Igi, K. Ito, H. Taira, M. Motoki, H. Momose, (2000) Substrate specificity analysis of microbial transglutaminase by using proteinaceious protease inhibitors (SILs) as natural model substrates, The Journal of Biochemistry, 128, 415-425
  144. S. Taguchi, S. Komada, H. Momose, (2000) The complete amino acid substitutions at position 131 that is positively involved in cold adaptation of subtilisin BPN', Applied and Environmental Microbiology, 66, 37-42
  145. T. Tsuge, T. Fukui, H. Matsusaki, S. Taguchi, G. Kobayashi, A. Ishizaki, Y. Doi, (2000) Molecular cloning of two (R)-specific enoyl CoA hydratase genes from Pseudomonas aeruginosa and their use for polyhydroxyalkanoate biosynthesis, FEMS Microbiology Letters, 184, 193-198
  146. H. Sasakawa, A. Tamura, S. Fujimaki, S. Taguchi, K. Akasaka, (1999) Secondary structures and structural fluctuation in a dimer protein, Streptomyces subtilisin inhibitor, The Journal of Biochemistry, 126, 859-865
  147. S. Taguchi, A. Ozaki, T. Nonaka, Y. Mitsui, H. Momose, (1999) A cold-adapted protease engineered by experimental evolution system, The Journal of Biochemistry, 126, 689-693
  148. H. Sasakawa, A. Tamura, K. Akasaka, S. Taguchi, Y. Miyake, M. Kainosho, (1999) Backbone 1H, 13C and 15N resonance assignments of Streptomyces subtilisin inhibitor, Journal of Biomolecular NMR, 14, 285-286
  149. S. Taguchi, T. Ogawa, T. Endo, H. Momose, (1998) Identification of a structural gene encoding a metallothionein-like domain that includes a putative regulator protein for Streptomyces protease gene expression, Bioscience, Biotechnogy, and Biochemistry, 62, 2476-2479
  150. Y. Miyota, S. Kodama, H. Momose, S. Taguchi, (1998) Quantitative assay system for specific enzyme activity using antibody: the case of protease, subtilisin BPN', Journal of Biotechnology, 66, 157-163
  151. S. Taguchi, S. Yamada, S. Kojima, H. Momose, (1998) An endogenous target protease, SAM-P26, of Streptomyces protease inhibitor (SSI): purification, primary structure determination and enzymatic characterization, The Journal of Biochemistry, 124, 804-810
  152. S. Taguchi, P. Bulet, J. A. Hoffmann, (1998) A novel insect defensin from the ant Formica rufa, Biochimie, 80, 343-346
  153. S. Taguchi, A. Ozaki, H. Momose, (1998) Engineering of a cold-adapted protease by sequential random mutagenesis and a screening system, Applied and Environmental Microbiology, 64, 492-495
  154. S. Taguchi, S. Kojima, M. Terabe, Y. Kumazawa, H. Kohriyama, M. Suzuki, K. Miura, H. Momose, (1997) Molecular phylogenetic characterization of Streptomyces protease inhibitor family, Journal of Molecular Evolution, 44, 542-551
  155. S. Taguchi, T. Ogawa, T. Endo, H. Momose, (1997) A gene homologous to the Streptomyces chymotrypsin-like protease (SAM-20) gene is tandemly located, Bioscience, Biotechnogy, and Biochemistry, 61, 909-913
  156. S. Taguchi, S. Kojima, M. Terabe, Y. Kumazawa, H. Kohriyama, M. Suzuki, K. Miura, H. Momose, (1997) Molecular phylogenetic characterization of Streptomyces protease inhibitor family, Journal of Molecular Evolution, 44, 542-551
  157. H. Kano, S. Taguchi, H. Momose, (1997) Cold adaptation of a mesophilic serine protease, subtilisin, by in vitro random mutagenesis, Applied Microbiology and Biotechnology, 47, 46-51
  158. M Suzuki, S. Taguchi, S. Yamada, S. Kojima, K. Miura, H. Momose, (1997) A novel member of subtilisin-like protease family from Streptomyces albogriseolus, Journal of Bacteriology, 179, 430-438
  159. S. Taguchi, A. Ozaki, K. Nakagawa, H. Momose, (1996) Functional mapping of amino acid residues responsible for antibacterial action of apidaecin, Applied and Environmental Microbiology, 62, 4652-4655
  160. A. Kuramoto, A. Lezhava, S. Taguchi, H. Momose, H. Kinashi, (1996) The location and deletion of the genes which code for SSI-like protease inhibitors in Streptomyces species by pulsed-field gel electrophoresis, FEMS Microbiology Letters, 139, 37-42
  161. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura, (1996) New subtilisin-trypsin inhibitors produced by Streptomyces: primary structures and their relationship to other proteinase inhibitors from Streptomyces, Biochimica et Biophysca Acta, 1292, 233-240
  162. S. Taguchi, S. Kojima, K. Miura, H. Momose, (1996) Taxonomic characterization of closely related Streptomyces spp. based on the amino acid sequence analysis of protease inhibitor proteins, FEMS Microbiology Letters, 135, 169-173
  163. S. Taguchi, M. Suzuki, S. Kojoma, K. Miura, H. Momose, (1995) Streptomyces serine protease (SAM-P20): Recombinant production, characterization, and interaction with endogenous protease inhibitor, Journal of Bacteriology, 177, 6638-6643
  164. S. Taguchi, T. Endo, Y. Naoi, H. Momose, (1995) Molecular cloning and sequence analysis of a gene encoding an extracellular serine protease from Streptomyces lividans 66, Bioscience, Biotechnogy, and Biochemistry, 59, 1386-1388
  165. S. Taguchi, S. Misawa, Y. Yoshida, H. Momose, (1995) Microbial secretion of biologically active human transforming growth factor α fused to the Streptomyces protease inhibitor, Gene, 159, 239-243
  166. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura, (1995) A subtilisin inhibitor produced by Streptomyces bikiniensis possesses a glutamine residue at reactive site P1, The Journal of Biochemistry, 117, 609-613
  167. S. Taguchi, A. Odaka, Y. Watanabe, H. Momose, (1995) Molecular characterization of a gene encoding extracellular serine protease isolated from a subtilisin inhibitor-deficient mutant of Streptomyces albogriseolus S-3253, Applied and Environmental Microbiology, 61, 180-186
  168. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura, (1994) Primary structure and inhibitory properties of subtilisin-chymotrypsin inhibitor from Streptomyces virginiae, European Journal of Biochemistry, 226, 627-632
  169. M. Terabe, S. Kojima, S. Taguchi, H. Momose, K. Miura, (1994) Three novel subtilisin-trypsin inhibitors from Streptomyces: primary structures and inhibitory properties, The Journal of Biochemistry, 116, 1156-1163
  170. S. Kojima, M. Terabe, S. Taguchi, H. Momose, K. Miura, (1994) Primary structure and inhibitory properties of a proteinase inhibitor produced by Streptomyces cacaoi, Biochimica et Biophysica Acta, 1207, 120-125
  171. S. Taguchi, K. Nakagawa, M. Maeno, H. Momose, (1994) In vivo monitoring system for structure-function relationship analysis of the antibacterial peptide Apidaecin, Applied and Environmental Microbiology, 60, 3566-3572
  172. T. Tange, S. Taguchi, H. Momose, (1994) Improvement of a useful enzyme (subtilisin BPN') by an experimental evolution system, Applied Microbiology and Biotechnology, 41, 239-244
  173. S. Taguchi, S. Kojima, M. Terabe, K. Miura, H. Momose, (1994) Comaparative studies on the primary structures and inhibitory properties of subtilisin-trypsin inhibitors from Streptomyces, European Journal of Biochemistry, 220, 911-918
  174. M. Maeno, S. Taguchi, H. Momose, (1993) Production of antibacterial peptide ‘Apidaecin' using the secretory expression system of Streptomyces, Biosci. Biotech. Biochem., 57, 1206-1207
  175. S. Taguchi, Y. Yoshida, K. Matsumoto, H. Momose, (1993) Improved leader and putative terminator sequences for high-level production of Streptomyces subtilisin inhibitor in Escherichia coli, Applied Microbiology and Biotechnology, 39, 732-737
  176. S. Taguchi, H. Kikuchi, M. Suzuki, S. Kojima, M. Terabe, K. Miura, T. Nakase, H. Momose, (1993) Streptomyces subtilisin inhibitor-like proteins are distributed widely in streptomycetes, Applied and Environmental Microbiology, 59, 4338-4341
  177. M. Maeno, S. Taguchi, H. Momose, (1993) Production of antibacterial peptide ‘Apidaecin' using the secretory expression system of Streptomyces, Bioscience, Biotechnogy, and Biochemistry, 57, 1206-1207
  178. S. Taguchi, Y. Yoshida, K. Matsumoto, H. Momose, (1993) Improved leader and putative terminator sequences for high-level production of Streptomyces subtilisin inhibitor in Escherichia coli, Applied Microbiology and Biotechnology, 39, 732-737
  179. S. Taguchi, H. Kikuchi, S. Kojima, I. Kumagai, T. Nakase, K. Miura H. Momose, (1993) High frequency of SSI-like protease inhibitors among Streptomyces, Bioscience, Biotechnogy, and Biochemistry, 57, 522-524
  180. Y. Ueda, S. Taguchi, K. Nishiyama, I. Kumagai, K. Miura, (1993) Effect of a rare leucine codon, TTA, on expression of a foreign gene in Streptomyces lividans, Biochimica et Biophysica Acta, 1172, 262-266
  181. S. Taguchi, Y. Yoshida, I. Kumagai, K. Miura, H. Momose, (1993) Effect of downstream message secondary structure on the secretory expression of the Streptomyces subtilisin inhibitor, FEMS Microbiology Letters, 107, 185-190
  182. S. Taguchi, S. Kojima, I. Kumagai, H. Ogawara, K. Miura, H. Momose, (1992) Isolation and partial characterization of SSI-like protease inhibitors from Streptomyces, FEMS Microbiology Letters, 99, 293-298
  183. S. Taguchi, K. Furukawa, H. Momose, M. Kishimoto, (1992) Optimization of the microbial production of a protein (SSI) using an indicator host-vector system, Journal of Fermentation and Bioengineering, 73, 317-318
  184. S. Taguchi, M. Maeno, H. Momose, (1992) Extracellular production system of heterologous peptide driven by a secretory protease inhibitor of Streptomyces, Applied Microbiology and Biotechnology, 36, 749-753
  185. S. Taguchi, K. Nishiyama, I. Kumagai, H. Momose, K. Miura, (1991) Relationship between utilization of dual translational initiation signals and protein processing in Streptomyces, Molecular Genetics and Genetics MGG, 226, 328-331
  186. S. Taguchi, I. Kumagai, K. Miura, (1990) Comparison of secretory expression in Escherichia coli and Streptomyces of Streptomyces subtilisin inhibitor (SSI) gene, Biochimimica et Biophysica Acta, 1049, 278-285
  187. S. Taguchi, I. Kumagai, J. Nakayama, A. Suzuki, K. Miura, (1989) Efficient extracellular expression of a foreign protein in Streptomyces using secretory protease inhibitor (SSI) gene fusion, Nature Biotechnology, 7, 1063-1066
  188. S. Taguchi, K. Nishiyama, I. Kumagai, K. Miura, (1989) Analysis of transcriptional control regions in the Streptomyces subtilisin-inhibitor-encoding gene, Gene, 84, 279-286
  189. S. Obata, S. Taguchi, I. Kumagai, K. Miura, (1989) Molecular cloning and nucleotide sequence determination of gene encoding Streptomyces subtilisin inhibitor (SSI), The Journal of Biochemistry, 105, 367-371
  190. K. Miura, I. Kumagai, S. Obata, S. Kojima, S. Taguchi, (1988) Partial alteration of a protein Streptomyces subtilisin inhibitor by site-directed mutagenesis, Proceedings of the Japan Academy, 64, 147-149

総説・解説等

  1. 田口精一, 世界初、海水中で分解できる“強靭性”と“生分解性”を両立したプラスチックの大量生産に成功(下), 科学機器, 916, 14-21 (2024/10)
  2. 田口精一, 世界初、海水中で分解できる“強靭性”と“生分解性”を両立したプラスチックの大量生産に成功(上), 科学機器, 915, 10-17 (2024/09)
  3. 高 相昊, 田口精一, メンブレンベシクル創発の新原理~バイオプラスチック合成が“引き金”~, 化学と生物, 61(5), 217-219 (2023/05)
  4. 田口精一, 高 相昊, 生分解性「多元ポリ乳酸LAHB」の研究ストーリー:乳酸重合酵素誕生・オリゴマー分泌生産発見・膜小胞創発, 生物工学会誌, 100(9), 483-488 (2022/09)
  5. J.M. Nduko, S. Taguchi, Microbial production of biodegradable lactate-based polymers and olgomeric building blocks from renewable and waste resources, Front. Bioeng. Biotechnol., 8(618077) (2021)
  6. S. Taguchi, K. Matsumoto, Evolution of polyhydroxyalkanoate synthesizing systems toward a sustainable plastic industry, Polym. J., 53, 67-79 (2020)
  7. 田口精一,ノーベル賞受賞者から香る研究観, 【随縁随意】, 日本生物工学会, 98(5), 227-227 (2020)
  8. 田口精一,「多元ポリ乳酸」の生合成と生分解:メカニズム解明の鍵"オリゴマー", 化学と生物, 日本農芸化学会誌, 58(4), 248-254 (2020)
  9. 田口精一, ファージディスプレイ法の登場による進化分子工学の大きな発展―知的な進化マシナリー(特別解説2018年ノーベル化学賞を読み解く化学賞Part II, 化学), 月刊化学, 化学同人, 73(12), 17-20 (2018)
  10. M.F. Chek, A. Hiroe, T. Hakoshima, K. Sudesh, S. Taguchi, PHA synthase (PhaC): Interpreting the function of bioplastic-producing enzyme from a strauctural perspective, Appl. Microbiol. Biotechnol., 1131-1141 (2018)
  11. 松本謙一郎, 廣江綾香, 田口精一, オリゴマー分泌発見に基づいたポリ乳酸生産プロセスの短縮化, バイオサイエンスとインダストリー(バイオインダストリー協会), 76(6), 462-466 (2018)
  12. T. Hiraishi, S. Taguchi, Enzymes catalyzing the synthesis and degradation of beta-linked biopolymers and their applications, Biodegradable Polymers: Recent Developments and New Perspectives, Mini-Reviews in Organic Chemistry, 14(6), 1-32 (2017)
  13. 田口精一, 石井大輔, 多元ポリ乳酸の生合成及び物性・機能, 「特集 新しいものづくりへの挑戦」, プラスチックスエージ = Plastics age, 63(1), 71-75 (2017)
  14. 大井俊彦, 松本謙一郎, 田口精一, 植物バイオマスから合成される高分子, 「Polymers synthesized from plant biomass」, 高分子科学最近の進歩, 高分子, 66(6), 296-300 (2017)
  15. 田口精一, 多種多芸の微生物バイオポリマー:透明で硬軟多様で接着性も, 日本接着学会誌総説, 52(2), 44-49 (2016)
  16. 門屋亨介, 滝沢憲治, 松本謙一郎, 大井俊彦, 田口精一, 乳酸ベースバイオプラスチックの創製と「風船型」微生物工場の誕生, 「コンバーティングとホワイトバイオ」コンバーテック, 44(4), 125-127 (2016)
  17. 田口精一, バイオプラスチックの本格的生産に資する風船型微生物工場「特集 プラスチック産業のエコロジーへの取組」, プラスチックス, 日本プラスチック工業連盟誌, 67(11), 30-33 (2016)
  18. 田口精一, 合成生物学によって創発される「多元ポリ乳酸」, バイオプラジャーナル, 62(2), 18-26 (2016)
  19. 田口精一, 微生物プラスチック工場 : 石油化学工業から生物化学工業へ (特集 ポリマー生産プロセスの現状と将来展望), 化学工学, 79(4), 310-312 (2015)
  20. 田口精一, 乳酸重合酵素が駆動する乳酸ポリマー微生物工場とポリ乳酸の高機能化~「多元ポリ乳酸」への展開~, 『バイオマスプラスチックの新展開』, 月刊 『BIO INDUSTRY』, シーエムシー出版, 32(2), 26-35 (2015)
  21. S. Taguchi, T. Ooi, K. Mizuno, H. Matsusaki, Advances and needs for endotoxin-free production strains, Appl. Microbiol. Biotechnol., 99, 9349-9360 (2015)
  22. K. Matsumoto, S. Taguchi, Biosynthetic polyesters consisting of 2-hydroxyalkanoic acids: current challenges and unresolved questions, Appl. Microbiol. Biotechnol., 97(18), 8011-8021 (2013)
  23. 松本謙一郎, ジョン・マサニ・ンドウコ, 田口精一, 乳酸発酵と乳酸ポリマー発酵のメタボリックケミストリー, 化学と生物, 日本農芸化学会誌, 51(7), 448-456 (2013)
  24. K. Matsumoto, S. Taguchi, Enzyme and metabolic engineering for the production of novel polymers: crossover of biological and chemical processes, Curr. Opin. Biotechnol., 24(6), 1054-1060 (2013)
  25. 松本謙一郎, 田口精一, バイオプラ最前線 微生物はどこまでのポリエステルを合成できるか, バイオプラジャーナル, 12(4), 12-17 (2013)
  26. 大井俊彦, 松本謙一郎, 門屋亨介, 田口精一, 植物バイオマスから微生物バイオポリマー生産のための一貫プロセス開発, 高分子論文集:特集号「持続可能な社会に向けた高分子」(総合論文), 70(12), 675-683 (2013)
  27. 田口精一, Microbial Plastic Factory — 酵素工学研究が駆動する多元ポリ乳酸創製—, 酵素工学研究会誌, 68, 11-16 (2012)
  28. 松本謙一郎, 田口精一, Microbial Plastic Factory―ポリ乳酸から多元ポリ乳酸の時代へ―, 創立90周年記念特集「バイオリファイナリーの今、そして未来」, 日本生物工学会誌, 90(7), 411-414 (2012)
  29. 松本謙一郎, 田口精一, 生体触媒の連携が実現する”一気通貫型”の乳酸ポリマー生合成プロセス-乳酸重合酵素の発見から物性解析まで-, 高分子論文集, 68, 271-280 (2011)
  30. 田口精一, 乳酸ポリマー合成微生物工場の誕生, バイオサイエンスとインダストリー, 69(5), 375-379 (2011)
  31. 田口精一, 乳酸ポリマー生産用微生物工場:石油原料からバイオマス原料へ, PETROTECH, 34, 867-872 (2011)
  32. 田口精一, 乳酸重合酵素が駆動する乳酸ポリマーの完全生合成プロセス, 日本応用酵素協会誌, 45, 1-9 (2011)
  33. S. Hashimoto, S. Taguchi, Activity improvement of antimicrobial peptides by a chemical modification approach: Toward the creation of novel types of antimicrobial agents, Org. Chem., 7, 282-289 (2010)
  34. S. Taguchi, Current advances in microbial cell factories for lactate-based polyesters driven by lactate-polymerizing enzymes: toward further creation of new LA-based polyesters, Polymer Degradation and Stability, 95, 1421-1428 (2010)
  35. K. Matsumoto, S. Taguchi, Enzymatic and whole-cell synthesis of lactate-containing polyesters: towards the complete biological production of polylactate, Appl. Microbiol. Biotechnol., 85, 921-932 (2010)
  36. 田口精一, 乳酸ポリマー合成の新展開:化学工場から微生物工場へ, 繊維学会誌, 66(8), 268-273 (2010)
  37. 田口精一, バイオポリマー合成プロセス開発の変遷--化学工場→微生物工場→植物工場, ケミカル・エンジニアリング, 55(10), 770-777 (2010)
  38. 田口精一, 乳酸ポリマー完全生合成システムの幕開け―新原理に基づく微生物工場の誕生―, バイオプラジャーナル「最前線」, 35, 18-23 (2009)
  39. 山田美和, 田口精一, BIO R&D 乳酸ポリマー生産用微生物工場を駆動するエンジニア酵素, BIOINDUTRY, 26(7), 54-62 (2009)
  40. 田口精一, BP最前線 乳酸ポリマー完全生合成システムの幕開けー新原理に基づく微生物工場の誕生, バイオプラジャーナル, 9(3), 18-23 (2009)
  41. T. Hiraishi, S. Taguchi, Enzyme-catalyzed synthesis and degradation of biopolymers, Mini-Reviews in Org. Chem., 6(1), 44-54 (2009)
  42. 鈴木陽一, 田口精一, バイオポリマー合成プロセス研究の新潮流, 未来材料, 8(1), 56–61 (2008)
  43. 山田美和, 松本謙一郎, 田口精一, バイオプラスチック生産のための微生物工場, 繊維学会誌, 64(11), 365-370 (2008)
  44. 田口精一, 阿部敬悦, 礒部公安, 新産業創出に挑むキィーエンザイムの顔ぶれ, 日本生物工学会誌, 86(11) (2008)
  45. C.T. Nomura, S. Taguchi, PHA synthase engineering toward superbiocatalysts for custom-made biopolymers, Appl. Microbiol. Biotechnol. (Mini-review), 73(5), 969-979 (2007)
  46. 松本謙一郎, 田口精一, 酵素進化工学に基づくバイオポリマー生物生産システムの開発研究, バイオサイエンスとインダストリー, 65(7), 334-339 (2007)
  47. 山田美和, 田口精一, バイオプラスチックの"輪廻転生"―合成・調節・分解―, 化学, 化学同人, 62, 66-67 (2007)
  48. 田口精一, 平石知裕, "酵素"が演出するバイオプラスチックの生合成と生分解, 未来材料, 6(7), 44–51 (2006)
  49. 田口精一, 田島健次, 佐藤康治, バイオプラスチック合成研究の最前線-in vivoとin vitroのクロスオーバー, 高分子加工, 55(1), 30-43 (2006)
  50. 山田美和, 松本謙一郎, 田口精一, バイオを駆使した環境調和型プラスチックの創製―微生物生産から植物生産へ, 日本油化学会誌, 5, 523-532 (2005)
  51. 田口精一, 高性能バイオプラスチック創製のための酵素進化工学とナノプロセッシグ, 化学工業, 56(6), 468-473 (2005)
  52. 田口精一, バイオプラスチックのつくられ方とつくり方―生合成調節機構と酵素進化工学による新規プラスチック創製, 蛋白質核酸酵素, 50(3), 262-269 (2005)
  53. 田口精一, バイオが演出する"グリーンプラ", 高分子, 60, 30-31 (2004)
  54. 田口精一, 酵素進化工学による多様なバイオプラスチックの創製, 日本農芸化学会誌, 78, 30-31 (2004)
  55. S. Taguchi, Y. Doi, Evolution of polyhydroxyalkanoate (PHA) production system by "enzyme evolution”: successful case studies of directed evolution, Macromolecular Bioscience., 4, 145-156 (2004)
  56. 田口精一, 柘植丈治, 土肥義治, バイオプラスチック生産研究の国際動向, 化学経済, 3, 32-38 (2004)
  57. 田口精一, 酵素進化工学による"グリーンプラ"の創製, バイオサイエンスとインダストリー, 60, 30-31 (2002)
  58. 田口精一, バイオプラスチック生産における進化分子工学, 化学工業(総説), 53(7), 22-28 (2002)
  59. A. Maehara, S. Taguchi, T. Nishiyama, S. Ueda, H. Nakano, T. Yamane, Y. Doi, Molecular characterization of a regulatory protein (PhaR) involved in PHA biosynthesis, RIKEN Review (Focused on Ecomolecular Science Research), 42, 77-80 (2001)
  60. K. Taguchi, T. Tsuge, K. Matsumoto, S. Nakae, S. Taguchi, Y. Doi, Investigation of metabolic pathways for biopolyester production, RIKEN Review (Focused on Ecomolecular Science Research), 42, 71-74 (2001)
  61. S. Taguchi, A. Maehara, K. Takase, M. Nakahjara, Y. Doi, In vivo assay system of the polymerase as a key enzyme for PHA biosynthesis, RIKEN Review (Focused on Ecomolecular Science Research), 42, 3-6 (2001)
  62. 松崎弘美, 田口精一, 土肥義治, 環境調和型バイオポリエステル研究の新展開:代謝制御工学から分子生理まで, 日本油化学会誌, 48, 1353-1364 (1999)
  63. 田口精一, 進化分子工学的手法によるタンパク質機能の改変と有用物質生産への応用及び代謝工学による新規有用物質の合成に関する最近の動向に関する調査報告書(平成10年度), 新化学発展協会, 1-58 (1999)
  64. 田口精一, 放線菌におけるプロテアーゼ・インヒビター相互作用系, 財団法人日産科学振興財団・平成8年度研究成果報告書 (1997)
  65. 田口精一, 枯草菌(納豆類縁金)プロテアーゼの実験進化的研究, 財団法人タカノ農芸化学研究助成財団・平成7年度助成研究報告書 (1997)
  66. 百瀬春生, 田口精一, 有用微生物の低温適応化に関する遺伝学的研究(2), 岩谷財団研究報告書 (1993)
  67. 百瀬春生, 田口精一, 有用微生物の低温適応化に関する遺伝学的研究(1), 岩谷財団研究報告書 (1992)
  68. 田口精一, 大腸菌の形質転換, SUTBULLETIN, 生物実験セミナー (1992)
  69. 田口精一, 大腸菌の培養, SUTBULLETIN, 生物実験セミナー (1992)
  70. 田口精一, マルチタレント生物と脳天気生物, SUTBULLETIN, 私の研究 (1992)
  71. 田口精一, 放線菌プロテアーゼインヒビターSSI, 遺伝子の情報発現に関する研究, SUTBULLETIN, 科学教養講座, 9, 19-25 (1992)
  72. 田口精一, 百瀬春生:放線菌における異種蛋白質分泌生産系, 蛋白質核酸酵素(共立出版臨時増刊), 蛋白質工学の進展, 37, 245-257 (1992)
  73. S. Taguchi, Communication between protease and protease inhibitor in the Streptomyces world, Actinomycetologica, 9, 216-227 (1992)
  74. S. Taguchi, Streptomyces subtilisin inhibitor: genetical characterization and its application, Actinomycetologica (Review of SAJ Award ,Invited Lecture), 6(1), 9-20 (1992)
  75. 田口精一, 放線菌における異種蛋白質の分泌生産系の構築, 平成2年度理大研究助成金研究実績報告書 (1991)
  76. 三浦謹一郎, 熊谷泉, 小畑充生, 小島修一, 田口精一, 遺伝子工学によるプロテアーゼの人工的改変, 東京大学工学部紀要A, 64(25), 58-59 (1987)

著書

  1. 田口精一, 乳酸ポリマーP(LAHB)の微生物生産, バイオリアクターのスケールアップと物質生産事例集, エヌ・ティー・エス出版, 287-295/366 (2021)
  2. Y. Miyahara, A. Hiroe, S. Sato, T, Tsuge, S. Taguchi, Chapter 8 Microbial Polyhydroxyalkanoates (PHAs): From Synthetic Biology to Industrialization, Biopolymers for Biomedical and Biotechnological Applications, Wiley-VCH Verlag Gmbh&Co. KGaA., 231-264 (2020)
  3. 田口精一, 山田美和, 第3章 生分解性プラスチックの高性能化・高機能化・複合化技術, 第6節 「オリゴマー」が鍵:バイオプラスチックの生合成と生分解, 生分解性プラスチックの素材・技術開発~海洋プラスチック汚染問題を見据えて~, エヌ・ティー・エス出版, 287-295/366 (2019)
  4. 田口精一, 松本謙一郎, 第Ⅲ編 ポリ乳酸の高性能化と生分解性、第2章 多元ポリ乳酸の合成/分解の交差点:「オリゴマー」, 生分解性プラスチックの環境配慮設計指針, シーエムシー出版, 287-295/336 (2019)
  5. 松本謙一, 田口精一, 第Ⅱ編 微生物産生ポリエステルの合成と生分解性、第3章 非天然型ポリヒドロキシアルカン酸の分解性とその評価法, 生分解性プラスチックの環境配慮設計指針, シーエムシー出版, 287-295/336 (2019)
  6. 田口精一, 第5編 バイオプラスチック, 第28章「多元ポリ乳酸」生合成の新展開:オリゴマー分泌発見によるプロセス革新, プラスチックの資源循環に向けたグリーンケミストリーの要素技術, シーエムシー出版, 287-295/336 (2019)
  7. 田口精一, 第4編 生産・技術, 3章 昆虫由来抗菌ペプチドの作用メカニズム解明と進化工学, 天然系抗菌・防カビ剤の開発と応用, シーエムシー出版, 287-295/239 (2019)
  8. A. Hiroe, M. F. Chek, T. Hakoshima, K. Sudesh, S. Taguchi, Synthesis of Polyesters III: Acyltransferase as Catalyst, Enzymatic Polymerization towards Green Polymer Chemistry (Springer), 199-231 (2019)
  9. C. Utsunomia, S. Taguchi, Microbial secretion system of lactate-based oligomers and its application: Biosynthesis, Green Polymer Chemistry: New products, Processes, and Applications, Chapter 4, ACS Symposium Series Vol. 1310, American Chemical Society, 41-60 (2018)
  10. T. Hiraishi, S. Taguchi, Enzymes, The synthesis and degradation of beta-linked biopolymers and theirs applications, Biodegradable polymers: recent developments and new perspectives, Mini-Reviews in Organic Chemistry, IAPC publishing, 14(6), 1-32 (2017)
  11. S. Taguchi, Bioengineering of Polyhydroxyalkanoates (PHAs), Encyclopedia of Polymer Science and Technology, Chapter 13. Microbial Plastic Factory: Synthesis and Properties of the New Lactate-Based Biopolymers, Wiley Blackwell (John Wiley & Sons), DOI:10.1002/0471440264.pst655 (2017)
  12. 田口精一, 第2章 微生物の生体成分利用, 第9節 生活に浸透する微生物ポリマーの威力, 応用微生物学(第3版), 文永堂出版, 93-99/184 (2016)
  13. 田口精一, 門屋亨介, 大井俊彦, 第7章 タンパク質の機能と進化, カラー 生化学 第4版, 西村書店, 209-256/1193 (2015)
  14. K. Matsumoto, K. Tajima, S. Taguchi, Biosynthesis of polymers, Encyclopedia of Polymeric Nanomaterials, Springer Berlin Heidelberg, 1-12 (2015)
  15. J. M. Nduko, J. Sun, S. Taguchi, Biosynthesis, properties, and biodegradation of lactate-based polymers, Green Polymer Chemistry: Biobased Materials and Biocatalysis, ACS Symposium Series Vol. 1192, American Chemical Society, 113-131 (2015)
  16. Y. Song, J. M. Nduko, K. Matsumoto, S. Taguchi, Microbial factory for the production of polyesters: A new platform of Corynebacterium glutamicum, Corynebacterium glutamicum: From Systems Biology to Biotechnological Applications, Caister Academic Press, 137-148 (2015)
  17. 田口精一, 微生物ポリエステル, 化学便覧 応用化学編 第7編, 丸善出版 (2014)
  18. 田口精一, 2章 1節 酵素進化工学によって創出される多様なバイオポリマー, 3編 1節 進化分子工学のケーススタディー:産業酵素と抗菌ペプチド, 進化分子工学—高速分子進化によるタンパク質・核酸の開発, エヌ・ティー・エス出版, 319-329/466 (2013)
  19. 田口精一, 2章 1節 酵素進化工学によって創出される多様なバイオポリマー, 3編 1節 進化分子工学のケーススタディー:産業酵素と抗菌ペプチド, 進化分子工学—高速分子進化によるタンパク質・核酸の開発, エヌ・ティー・エス出版, 287-295/466 (2013)
  20. J. M. Nduko, K. Matsumoto, S. Taguchi, Chapter 13 Microbial plastic factory: Synthesis and properties of the new lactate-based biopolymers, Green Polymer Chemistry: Biocatalysis and Materials II, ACS Symposium Series, Vol. 1144, American Chemical Society, 175-197/447 (2013)
  21. T. Iwata, T. Tsuge, S. Taguchi, H. Abe, T. Tanaka: Polyhydroxyalkanoate, Handbook of R&D information Japan, Bio-based polymers, CMC publishing, 71-85 (2013)
  22. T. Hiraishi, S. Taguchi, Chapter 6 Protein engineering of enzymes involved in bioplastic metabolism, Protein Engineering – Technology and Application, INTECH, 133-165/174 (2013)
  23. 田口精一(総合監修&10章分担執筆), まえがき(編著より), 「生命システム工学 ―細胞を知り、改造し、超える―」, PartⅢ 細胞システム工学:第9章 バイオポリエステルの生産システム工学生命システム工学(DOJIN BIOSCIENCE SERIES)―進化分子工学から進化生命工学へ―, 化学同人, pp. 3-5、pp.177-204 (2012). ISBN-9784759815061
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  26. J.M. Nduko, S. Taguchi, Microbial production and properties of LA-based polymers and oligomers from renewable feedstock., Part of the Biofuels and Biorefineries book series (BIOBIO, volume 9) Production of Materials from Sustainable Biomass Resources (Springer), 361-390 (2012)
  27. J. M. Nduko, K. Matsumoto, S. Taguchi, Biological lactate-polymers synthesized by one-pot microbial factory: Enzyme and metabolic engineering, Biobased Monomers, Polymers, and Materials, ACS Symposium Series, Vol. 1105, American Chemical Society, 215-235/360 (2012)
  28. S. Taguchi, T. Iwata, H. Abe, Y. Doi: Polymers in biology and medicine, 9.09 Poly(hydroxyalkanoate)s, Polymer Science: A Comprehensive Reference, Polymers in Biology and Medicine, Elsevier, vol. 9, 157-182/560 (2012)
  29. 北村昌也, 田口精一, 4章 コンストラクトの作製 Ⅱ.DNAの増幅法の原理とプロトコール, 「目的別で選べる核酸実験の原理とプロトコール」, 羊土社, 199-220 (2011)
  30. 越智杏奈, 渡辺剛, 田口精一, 1章 新しい植物由来ポリマー・材料の開発, 9節 微生物を用いた乳酸ポリマーのワンステップ重合法, 「植物由来ポリマー・複合材料の開発」, サイエンス&テクノロジー株式会社, 74-80 (2011)
  31. 田口精一, 第7章 バイオプロダクトと新プラットフォーム形成, 12. 乳酸ポリマーのワンポット微生物合成, エコバイオリファイナリー―脱石油社会へ移行するための環境ものづくり戦略―, シーエムシー出版, 237-245/252 (2010)
  32. 田口精一, 第5編 機能材料 第6章 バイオポリマーPHAと酵素分子進化工学, 酵素利用技術大系, 産業酵素の応用技術と最新動向, エヌ・ティー・エス出版, 920-925/1064 (2010)
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  34. 田口精一, 第7編 酵素を使うII―産業応用, 第26章 バイオプラスチックの合成・調節・分解に関わる酵素群の科学と工学, 産業酵素の応用技術と最新動向, シーエムシー出版, 257-271/345 (2009)
  35. 田口精一, 第5章 化成品素材の生産―バイオポリエステル―, 「微生物によるものづくり 化学法に代わるホワイトバイオテクノロジーの全て(バイオテクノロジーシリーズ)」, シーエムシー出版, 244-253/322 (2008)
  36. S. Taguchi, T. Tsuge: Natural polyester-related proteins: structure, function, evolution and engineering, Protein Engineering Handbook, WILEY-VCH Verlag GmbH, 877-914/901 (2008)
  37. 田口精一, バイオプラスチックの高機能化・再資源化技術, 第2編 バイオプラスチック創製のためのバイオテクノロジーからのアプローチ 1. 酵素系, エヌ・ティー・エス出版, 79-90/392 (2007)
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  39. 田口精一, 松本謙一郎, 第1編 第1章 バイオプロセスにおける有用物質生産のための生物, 第1編 第3章 進化分子工学による酵素の改質, バイオプラスチックの完全生合成, 「バイオプロセスハンドブック バイオケミカルエンジニアリングの基礎から有用物質生産・環境調和技術まで」, エヌ・ティ・エス出版, 3-11 および 91-103 (2007)
  40. 田口精一, バイオマスからのポリマーの発酵生産, エコマテリアルハンドブック, 176-178, 丸善 (2006)
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