Hidese, R., Sakai, K., Takenaka, M., Fushimi, K., Kudo, H., Tanaka, K., Nasuno, R., Vavricka, CJ.,Kondo, A., Hasunuma, T. (2025/06) Identification of subfamily specific residues within highly active and promiscuous alcohol dehydrogenases, ACS Catalysis, 15, 11931-11943
Tsuji, A., Inabe, K., Hidese, R., Kato, Y., Domingues, L., Kondo, A., Hasunuma, T. (2024/10) Pioneering precision in markerless strain development for Synechococcus sp. PCC 7002, Microbial Cell Factories, 23,268
Hidese, R., Ohira, T., Sakakibara, S., Suzuki, T., Shigi, N., Fujiwara. S. (2024/08) Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon, Thermococcus kodakarensis. mBio, 15(8), e0053424
Mori, H., Matsui, M., Bamba, T., Hori, Y., Kitamura, S., Toya, Y., Hidese, R., Yasueda, H., Hasunuma, T., Shimizu, H., Taoka, N., Kobayashi, S.(2024/07) Engineering Escherichia coli for efficient glutathione production, Metabolic Engineering, 84, 108-190
Kato, Y., Hidese, R., Matsuda, M., Ohbayashi, R., Ashida, H., Kondo, A., Hasunuma, T.(2024/02) Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria. Commun. Biol. 7(1), 233
Hidese, R., Ohbayashi, R., Kato, Y., Matsuda, M., Tanaka, K., Imamura, S., Ashida, H., Kondo, A., Hasunuma, T. (2023/12) ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels, Communications Biology, 6, 1285
Hidese, R., Matsuda, M., Kajikawa, M., Osanai, T., Kondo, A., Hasunuma, T. (2022/11) Metabolic and microbial community engineering for four-carbon dicarboxylic acid production from CO2-derived glycogen in the Cyanobacterium Synechocystis sp. PCC6803, ACS Synthetic Biology, 11, 4054-4064
Oyama, T., Kato, Y., Hidese, R., Matsuda, M., Matsutani, M., Watanabe, S., Kondo, A., Hasunuma, T. (2022/09) Development of a stable semi-continuous lipid production system of an oleaginous Chlamydomonas sp. mutant using multi-omics profiling, Biotechnology for Biofuels and Bioproducts, 15, 95
Fukuda, W., Osaki, M., Yasuda, Y., Hidese R., Higuchi, T., Umezawa, N., Fujiwara, S.* Mizohata, E.* (2022/05) Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12(5) 567
Kato, Y., Inabe, K., Hidese, R., Kondo, A., Hasunuma, T. (2022/01) Metabolomics-based engineering for biofuel and bio-based chemical production in microalgae and cyanobacteria: A review, Bioresource Technology, 344(A): 126196
Inabe, K., Miichi, A., Matsuda, M., Yoshida, T., Kato, Y., Hidese, R., Kondo, A., Hasunuma, T. (2021/12) Nitrogen availability affects the metabolic profile in Cyanobacteria, Metabolites, 11, 867
Kato, Y., Oyama, T., Inokuma, K., Vavricka, CJ., Matsuda, M., Hidese, R., Satoh, K., Oono, Y., Chang, JS., Hasunuma, T., Kondo, A. (2021/04) Enhancing carbohydrate repartitioning into lipid and carotenoid by disruption of microalgae starch debranching enzyme, Communications Biology, 4: 450
Fukuda, W., Yamori, Y., Hamakawa, M., Osaki, M., Fukuda, M., Hidese, R., Kanesaki, Y., Okamoto-Kainum, A., Kato, S., Fujiwara, S. (2020/02) Genes regulated by branched-chain polyamine in the hyperthermophilic archaeon Thermococcus kodakarensis, Amino Acids, 52, 287-299
Hidese, R.#, Matsuda, M.#, Osanai, T., Hasunuma, T.*, Kondo, A. (2020/01) Malic enzyme facilitates D-lactate production through increased pyruvate supply during anoxic dark fermentation in Synechocystis sp. PCC 6803, ACS Synthetic Biology, 9, 260-268 # equally contributed authors
Hidese, R., Toyoda, M., Yoshino, KI., Fukuda, W., Wihardja, GA., Kimura, S., Fujita, J., Niitsu, M., Oshima, T., Imanaka, T., Mizohata, E., Fujiwara, S. (2019/10) The C-terminal flexible region of branched-chain polyamine synthase facilitates substrate specificity and catalysis. The FEBS Journal, 286(19), 3926-3940
Yamori, Y., Hamakawa, M., Hidese, R., Fukuda, M., Atomi, H., Fukuda, W., Fujiwara, S. (2019/05) Branched-chain polyamine stabilizes RNA polymerase at elevated temperatures in hyperthermophiles. Amino Acids, 1-11
Sakihama, Y., Hidese, R., Hasunuma, T., Kondo, A. (2019/03) Increased flux in acetyl-CoA synthetic pathway and TCA cycle of Kluyveromyces marxianus under respiratory conditions. Scientific Reports, 9(1): 5319
Okano, H., Baba, M., Hidese, R., Iida, K., Li, T., Kojima, K., Takita, T., Yanagihara, I., Fujiwara, S., Yasukawa, K. (2018/08) Accurate fidelity analysis of the reverse transcriptase by a modified next-generation sequencing. Enzyme Microb Technol, 115: 81-85
Akasaka, N., Kato, S., Kato, S., Hidese, R., Wagu, Y., Sakoda, H., Fujiwara, S. (2018/07) Agmatine Production by Aspergillus oryzae Is Elevated by Low pH during Solid-State Cultivation. Appl Environ Microbiol, 17; 84(15)
Okano, H., Baba, M., Kawato, K., Hidese, R., Yanagihara, I., Kojima, K., Takita, T., Fujiwara, S., Yasukawa, K. (2018/03) High sensitive RNA detection by one-step RT-PCR using the genetically engineered variant of DNA polymerase with reverse transcriptase activity from hyperthermophilies, Journal of Bioscience and Bioengineering, 125(3), 275-281
Hidese, R., Kawato, K., Nakura, Y., Yasukawa, K., Yanagihara, I., Fujiwara, S. (2018/01) Thermostable DNA helicase improves the sensitivity of digital PCR, Biochemical and Biophysical Research Communications, 495(3), 2189-2194
Ishii, Y., Akasaka, N., Sakoda, H., Hidese, R., Fujiwara, S. (2018/01) Leucine responsive regulatory protein is involved in methionine metabolism and polyamine homeostasis in acetic acid bacterium Komagataeibacter europaeus, Journal of Bioscience and Bioengineering, 125(1), 67-75
Hidese, R., Tse, KM., Kimura, S., Mizohata, E., Fujita, J., Horai, Y., Umezawa, N., Higuchi, T., Niitsu, M., Oshima, T., Imanaka, T., Inoue, T., Fujiwara, S. (2017/11) Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine. The FEBS Journal, 284(21), 3684-3701
Yasukawa, K., Iida, K., Okano, H., Hidese, R., Baba, M., Yanagihara, I., Kojima, K., Takita, T., Fujiwara, S. (2017/10) Next-generation sequencing-based analysis of reverse transcriptase fidelity. Biochemical and Biophysical Research Communications, 492(2): 147-153
Hidese, R., Yamashita, K., Kawazuma, K., Kanai, T., Atomi, H., Imanaka, T., Fujiwara, S. (2017/09) Gene regulation of two ferredoxin:NADP+ oxidoreductases by the redox-responsive regulator SurR in Thermococcus kodakarensis, Extremophiles, 21(5): 903-917
Gao, L., Hidese, R., Fujiwara, S. (2017/09) Function of a thermophilic archaeal chaperonin is enhanced by electrostatic interactions with its targets, Journal of Bioscience and Bioengineering, 124(3): 283-288
Hidese, R., Im, KH., Kobayashi, M., Niitsu, M., Furuchi, T., Fujiwara, S. (2017/07) Identification of a novel acetylated form of branched-chain polyamine from a hyperthermophilic archaeon Thermococcus kodakarensis, Bioscience, Biotechnology, and Biochemistry, 81(9): 1845-1849
Okano, H., Baba, M., Yamasaki, T., Hidese, R., Fujiwara, S., Yanagihara, I., Ujiiye, T., Hayashi, T., Kojima, K., Takita, T., Yasukawa, K. (2017/05) High sensitive one-step RT-PCR using MMLV reverse transcriptase, DNA polymerase with reverse transcriptase activity, and DNA/RNA helicase, Biochemical and Biophysical Research Communications, 487(1): 128-133
Okano, H., Katano, Y., Baba, M., Fujiwara, A., Hidese, R., Fujiwara, S., Yanagihara, I., Hayashi, T., Kojima, K., Takita, T., Yasukawa, K. (2017/01) Enhanced detection of RNA by MMLV reverse transcriptase coupled with termostable DNA polymerase and DNA/RNA helicase, Enzyme and Microbial Technology, 96: 111-120
Fujiwara, A., Kawato, K., Kato, S., Yasukawa, K., Hidese, R., Fujiwara, S. (2016/05) Application of a Euryarchaeota-Specific Helicase from Thermococcus kodakarensis for Noise Reduction in PCR, Applied and Environmental Microbiology, 82(10): 3022-3031
Hidese, R., Ataka, K., Bill, E., Shima, S. (2015/07) CuI and H2O2 Inactivate and FeII Inhibits [Fe]-Hydrogenase at very low Concentrations, ChemBioChem, 16(13): 1861-1865
Akasaka, N., Astuti, W., Ishii, Y., Hidese, R., Sakoda, H., Fujiwara, S. (2015/06) Change in the plasmid copy number in acetic acid bacteria in response to growth phase and acetic acid concentration, Journal of Bioscience and Bioengineering, 119(6): 661-668
Akasaka, N., Ishii, Y., Hidese, R., Sakoda, H., Fujiwara, S. (2014/12) Enhanced production of branched-chain amino acids by Gluconacetobacter europaeus with a specific regional deletion in a leucine responsive regulator, Journal of Bioscience and Bioengineering, 118(6): 607-615
Hidese, R., Inoue, T., Imanaka, T., Fujiwara, S. (2014/07) Cysteine desulphurase plays an important role in environmental adaptation of the hyperthermophilic archaeon Thermococcus kodakarensis, Molecular Microbiology, 93(2): 331-345
Okada, K., Hidese, R., Fukuda, W., Niitsu, M., Takao, K., Horai, Y., Umezawa, N., Higuchi, T., Oshima, T., Yoshikawa, Y., Imanaka, T., Fujiwara, S. (2014/05) Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles, Journal of Bacteriology, 196(10): 1866-1876
Hidese, R., Nishikawa, R., Gao, L., Katano, M., Imai, T., Kato, S., Kanai, T., Atomi, H., Imanaka, T., Fujiwara, S. (2014/05) Different roles of two transcription factor B proteins in the hyperthermophilic archaeon Thermococcus kodakarensis, Extremophiles, 18(3): 573-588
Hidese, R., Mihara, H., Kurihara, T., Esaki, N. (2014/03) Global identification of genes affecting iron-sulfur cluster biogenesis and iron homeostasis, Journal of Bacteriology, 196(6):1238-1249
Akasaka, N., Sakoda, H., Hidese, R., Ishii, Y., Fujiwara, S. (2013/12) An efficient method using Gluconacetobacter europaeus to reduce an unfavorable flavor compound, acetoin, in rice vinegar production, Applied and Environmental Microbiology, 79(23): 7334-7342
Nagaoka, E., Hidese, R., Imanaka, T., Fujiwara, S. (2013/08) Importance and determinants of induction of cold-induced DEAD RNA helicase in the hyperthermophilic archaeon Thermococcus kodakarensis, Journal of Bacteriology, 195(15): 3442-3450
Hidese, R., Mihara, H., Kurihara, T., Esaki, N. (2012/10) Pseudomonas putida PydR, a RutR-like transcriptional regulator, represses the dihydropyrimidine dehydrogenase gene in the pyrimidine reductive catabolic pathway, Journal of Biochemistry, 152(4): 341-346
Hidese, R., Mihara, H., Esaki, N. (2011/07) Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors, Applied Microbiology and Biotechnology, 91(1): 47-61
Hidese, R., Mihara, H., Kurihara, T., Esaki, N. (2011/02) Escherichia coli dihydropyrimidine dehydrogenase is a novel NAD-dependent heterotetramer essential for the production of 5,6-dihydrouracil, Journal of Bacteriology, 193(4): 989-993
Hidese, R., Mihara, H., Esaki, N. (2009/09) Functional analysis of a novel NADH-dependent dihydropyrimidine dehydrogenase from Escherichia coli, Vitamins (Japan), 83(9): 528-532
Mihara, H., Hidese, R., Yamane, M., Kurihara, T., Esaki, N. (2008/08) The iscS gene deficiency affects the expression of pyrimidine metabolism genes, Biochemical and Biophysical Research Communications, 372(3): 407-411
Hidese, R., Fukuda, W., Niitsu, M., Fujiwara, S. Identification of branched-chain polyamines in hyperthermophiles, In Methods in Molecular Biology, Ruben Alcazar and Antonio F. Tiburcio (eds.). Heidelberg: Springer, pp. 81-94 (2018)
Fujiwara, S., Hidese, R., Inoue, T., Fukuda, W. Protein synthesis and polyamines in thermophiles: Effect of polyamines on nucleic acid maintenance and gene expression, In Polyamines, a universal molecular nexus for growth, survival and specialized metabolism, Tomonobu Kusano and Hideyuki Suzuki (eds.). Heidelberg: Springer, pp. 143-152 (2015/11)
Fukuda, W., Hidese, R., Fujiwara, S. Long-chain and branched polyamines in thermophilic microbes. In Polyamines, a universal molecular nexus for growth, survival and specialized metabolism, Tomonobu Kusano and Hideyuki Suzuki (eds.). Heidelberg: Springer, pp. 15-25 (2015)
