研究業績

原著論文(査読付き)

  1. がん細胞指向性リガンドを導入したポリグリセロールデンドリマーのアルギニンデリバリー評価
    • 板倉幸枝、大谷 亨
    • 高分子論文集., 23, http://doi.org/10.1295/koron.2017-0011 (2017).
  2. Crosslinked network with rotatable binding sites based on mono-carboxylated α-cyclodextrin [2]rotaxane capable of angiotensin III recognition
    • K. Ohmori, , T. Ooya, T. Takeuchi*
    • Chem. Eur. J., 23, 4708-4712 (2017).
  3. Enhanced solubilization of α-tocopherol by hyperbranched polyglycerol-modified β-cyclodextin
    • M. Kimura, T. Ooya*
    • J. Drug Delivery Science and Technology, 35, 30-33 (2016).
  4. Reflectometric interference spectroscopy-based sensing for evaluating biodegradability of polymeric thin films
    • T. Ooya, Y. Sakata, H. W. Choi, T. Takeuchii*
    • Acta Biomater., 38, 163-167 (2016).
  5. Polyglycerol Dendrimer of Generation 3 Encapsulates Amino Acids Bearing Two Amino Groups
    • T. Ooya*, H. Lee
    • ChemNanoMat , 1, 264-269 (2015).
  6. Amphiphilic Polymerizable Porphyrins Conjugated to a Polyglycerol Dendron Moiety as Functional Surfactants for Multifunctional Polymer Particles
    • M. Moriishi, Y. Kitayama, T. Ooya, T. Takeuchi*
    • Langmuir, 31, 12903-12910 (2015).
  7. Reflectometric Interference Spectroscopy-based Immunosensing Using Immobilized Antibody via His-tagged Recombinant Protein A
    • H. W. Choi, Y. Sakata, T. Ooya, Y. Kitayama, T. Takeuchi*
    • Journal of Bioscience and Bioengineering., 119, 195-199 (2015).
  8. Molecularly imprinted protein recognition thin films constructed by controlled/living radical polymerization
    • S. Sasaki, T. Ooya, Y. Kitayama, T. Takeuchi*
    • Journal of Bioscience and Bioengineering., 119, 200-205 (2015).
  9. Two-Layer Reflectometric Interference Spectroscopy-Based Immunosensing for C-Reactive Protein
    • A. Murata, T. Ooya, T. Takeuchi*
    • Microchimica Acta., 182, 307-313 (2015).
  10. Conjugated protein mimics with molecularly imprinted reconstructible and transformable regions assembled using space-filling prosthetic groups
    • T. Takeuchi*, T. Mori, A. Kuwahara, T. Ohta, A. Ohshita, H. Sunayama, Y. Kitayama, T. Ooya
    • Angewande Chemie. International Edition., 53, 12765-12770 (2014).
  11. Molecularly Imprinted Polymers for Catechin Recognition Prepared Using Dummy-Template Molecules
    • A. Kitamura, Y. Kitayama, T. Ooya, T. Takeuchi*
    • Chromatography , 35, 139-145 (2014)
  12. Precisely Controlled Molecular Imprinting of Glutathione-s-Transferase by Orientated Template Immobilization Using Specific Interaction with an Anchored Ligand on a Gold Substrate
    • Y. Kamaon, R. Matsuura, Y. Kitayama, T. Ooya, T. Takeuchi*
    • Polymer Chemistry., 5, 4764-4771 (2014).
  13. Fluorescent protein-imprinted polymers capable of signal transduction of specific binding events prepared by a site-directed two-step post-imprinting modification.
    • H. Sunayama, T. Ooya, T. Takeuchi*
    • Chemical Communications., 50, 1347-1349 (2014). DOI: 10.1039/c3cc47759b
  14. Supraparticles comprising molecularly imprinted nanoparticles and modified gold nanoparticles as a nanosensor platform,
    • A. Uchida, Y. Kitayama, E. Takano, T. Ooya, T. Takeuchi*
    • RSC Advances, 3, 25306-25311 (2013). DOI:10.1039/C3RA43660H
  15. Fluorescent molecularly imprinted polymer thin films for specific protein detection prepared with dansyl ethylenediamine-conjugated O-acryloyl L-hydroxyproline
    • Y. Inoue, A. Kuwahara, K. Ohmori, H. Sunayama, T. Ooya, T. Takeuchi*
    • Biosensors and Bioelectronics, 48, 113-119 (2013). DOI: 10.1016/j.bios.2013.03.005
  16. Hydrophilic molecularly imprinted polymers for bisphenol A prepared in aqueous solution
    • N. Inoue, T. Ooya, T. Takeuchi*
    • Microchimica Acta, 180, 1387-1392 (2013). DOI: 10.1007/s00604-013-0996-5
  17. Molecularly imprinted polymers prepared using protein-conjugated cleavable monomers followed by site-specific post-imprinting introduction of fluorescent reporter molecules
    • Y. Suga, H. Sunayama, T. Ooya, T. Takeuchi*
    • Chemical Communications., 49, 8450-8452 (2013). DOI: 10.1039/c3cc40484f
  18. Simple immobilization of antibody in organic/inorganic hybrid thin films for immunosensing,
    • A. Murata, T. Ooya, T. Takeuchi*
    • Biosensors and Bioelectronics, 43, 45-49 (2013).
  19. Microfluidic reflectometric interference spectroscopy-based sensing for exploration of protein-protein interaction condition
    • Y. Kurihara, M. Takama, M. Moribuchi, T. Ooya, T. Takeuchi*
    • Biosensors and Bioelectronics, 40, 247-251 (2013).
  20. 19F-, 1H-NMR, and fluorescence studies of interaction between 5-fluorouracil and polyglycerol dendrimers.
    • H. J. Lee, T. Ooya*
    • The Journal of Physical Chemistry B, 116, 12263-12267 (2012).
  21. Generation-dependent Host-Guest Interactions: Solution States of Polyglycerol Dendrimers of Generations 3 and 4 Modulate the Localization of a Guest Molecule.
    • H. J. Lee, T. Ooya*
    • Chemistry - A European Journal, 18, 10624-10629 (2012).
  22. Fabrication of Carboxylated Silicon Nitride Sensor Chips for Detection of Antigen-Antibody Reaction Using Microfluidic Reflectometric Interference Spectroscopy
    • Y. Kurihara, M. Takama, M. Sekiya, Y. Yoshihara, T. Ooya, T. Takeuchi*
    • Langmuir, 28, 13609-13615 (2012).
  23. Dummy Template-imprinted Polymers for Bisphenol A Prepared Using a Schiff base-type Template Molecule with Post-imprinting Oxidation.
    • E. Takano, Y. Taguchi, T. Ooya, T. Takeuchi*
    • Analytical Letters, 45, 1204-1213 (2012).
  24. Label-free Detection of C-reactive Protein Using Reflectometric Interference Spectroscopy-based Sensing System.
    • H. W. Choi, Y. Sakata, Y. Kurihara, T. Ooya, T. Takeuchi*
    • Analytica Chimica Acta, 728, 64-68 (2012).
  25. Molecularly Imprinted Microspheres for Bisphenol A Prepared Using a Microfluidic Device.
    • E. Takano, F. Tanaka, T. Ooya, T. Takeuchi*
    • Analytical Sciences, 28, 457-461 (2012).
  26. Dendritic Nanospace Constructed by Only Glycerol Units Enhanced Uptakes of a Fluorescent Molecule in Aqueous Solution
    • H. J. Lee, T. Ooya*
    • Chemical Communications., 48, 546-548 (2012).
  27. Protein Imprinted TiO2-coated Quantum Dots for Fluorescent Protein Sensing Prepared by Liquid Phase Deposition
    • J. Inoue, T. Ooya, T. Takeuchi*
    • Soft Matter, 7, 9681-9684 (2011).
  28. Label-free Detection of Glycoproteins using Reflectometric Interference Spectroscopy-based Sensing System with Upright Episcopic Illumination
    • H. W. Choi, H. Takahashi, T. Ooya, T. Takeuchi*
    • Analytical Methods, 3, 1366-1370 (2011).
  29. Fluorescent Protein Recognition Polymer Thin Films Capable of Selective Signal Transduction of Target Binding Events Prepared by Molecular Imprinting with a Post-Imprinting Treatment.
    • H. Sunayama, T. Ooya, T. Takeuchi*
    • Biosensor and Bioelectronics, 26, 458-462 (2010).
  30. Highly Selective Bisphenol A-imprinted Polymers Prepared by Atom Transfer Radical Polymerization.
    • S. Sasaki, T. Ooya, T. Takeuchi*
    • Polymer Chemistry, 1, 1684-1688 (2010).
  31. Synthesis of Structurally Well-Defined Triglyceryl Di-, Tri-, and Tetra-Fatty Acid Esters as New Oil Gelators.
    • M. Hamada, M. Terayama, K. Kaneko, T. Ooya, T. Kishimoto, N. Nakajima*
    • Synthesis-Stuttgart, 22, 3663-3669 (2008).
  32. Supramolecular Control of Polyplex Dissociation and Cell Transfection: Efficacy of Amino Groups and Threading Cyclodextrins in Biocleavable Polyrotaxanes.
    • A. Yamashita, D. Kanda, R. Katoono, N. Yui*, T. Ooya, A. Maruyama, H. Akita, K. Kogure, H. Harashima*
    • Journal of Controlled Release, 131, 137-144 (2008).
  33. Effect of Polymer Adsorption on The Water Structure at The Quartz/water Interface Studied by Optical Sum Frequency Generation.
    • H. Sano*, H. Yoshida, T. Oosugi, T. Murakami, Y. Takagawa, G. Mizutani, T. Ooya, N. Yui*
    • Surface Science, 601,5173-5179 (2007).
  34. Cationic Hydrogels of PEG Crosslinked by a Hydrolyzable Polyrotaxane for Cartilage Regeneration.
    • T. Ooya, T. Ichi, T. Furubayashi, M. Katoh, N. Yui*
    • Reactive and Functional Polymers, 67, 1408-1417 (2007).
  35. Molecular "Screw and Nut": a-Cyclodextrin Recognizes Polylactide Chirality.
    • Y. Ohya*, S. Takamido, K. Nagahama, T. Ouchi, T. Ooya, R. Katoono, N. Yui*
    • Macromolecules, 40, 6441-6444 (2007).
  36. Successful Low-energy Cardioversion Using a Novel Biodegradable Gel Pad: Feasibility of Treating Postoperative Atrial Fibrillation in Animals.
    • K. Iino, N. Yui, T. Ooya, R. Kawabata, S. Tomita, G. Watanabe*
    • Journal of Thoracic and Cardiovascular Surgery, 134, 1519-1525 (2007).
  37. 1H NMR Titration Study of Stimuli-Responsive Supramolecular Assemblies: Inclusion Complexes between PEG−b−PEI Copolymer- Grafted Dextran and Naphthalene-Appended g-Cyclodextrins via Double-Chain Inclusion.
    • Y. K. Joung, T. Ooya, N. Yui*
    • Journal of Inclusion Phenomena and Macrocyclic Chemistry, 57, 323-328 (2007).
  38. Preparation of Polypseudorotaxane Consisting of Fluorescent Molecule-modified Beta-cyclodextrins and Biotin-terminated Poly(propylene glycol) with High Yield
    • A. Ito, T. Ooya, N. Yui*
    • Journal of Inclusion Phenomena and Macrocyclic Chemistry, 57, 233-236 (2007).
  39. Modulating Rheological Properties of Supramolecular Networks by pH-Responsive Double-Axle Intrusion into g-Cyclodextrin.
    • Y. K. Joung, T. Ooya, N. Yui*
    • Advanced Materials, 19, 396-400. (2007).
  40. Molecular Mobility of Interlocked Structures Exploiting New Functions of Advanced Biomaterials.
    • N. Yui*, T. Ooya
    • Chemistry –A European Journal, 12, 6730-6737 (2006).
  41. Providing Natural Water Structure Surrounding Highly Mobile Maltose Groups Conjugated with Polyrotaxanes.
    • H. Hirose, H. Sano*, G. Mizutani, M. Eguchi, T. Ooya, N. Yui*
    • Polymer Journal, 38, 1093-1097 (2006).
  42. Synthesis, Characterization and pH-Triggered Dethreading of a-Cyclodextrin-Polyethylene Glycol Polyrotaxanes Bearing Cleavable Endcaps.
    • S. Loethen, T. Ooya, H. S. Choi, N. Yui*, D. H. Thompson*
    • Biomacromolecules, 7, 2501-2506 (2006).
  43. Molecular Recognition and Binding Properties of Cyclodextrin-Conjugated Polyrotaxanes.
    • H. S. Choi, A. Takahashi, T. Ooya, N. Yui*
    • ChemPhysChem, 7, 1668-1670 (2006).
  44. Synthesis of a Biocleavable Polyrotaxane-Plasmid DNA (pDNA) Polyplex and Its Use for The Rapid Non-viral Delivery of pDNA to Cell Nuclei.
    • A. Yamashita, N. Yui*, T. Ooya, A. Kano, A. Maruyama*, H. Akita, K. Kogure, H. Harashima*
    • Nature Protocol, 1, 2861-2869 (2006).
  45. pH-Sensitive Locomotion of Cyclodextrins in a Block-Selective Mobile Polyrotaxane.
    • H. S. Choi, A. Hirasawa, T. Ooya, D. Kajiwara, T. Hohsaka, N. Yui*
    • ChemPhysChem 7, 1671-1673 (2006).
  46. pH-Responsive Movement of Cucurbit[7]uril in a Dual Polypseudorotaxane: Contribution of Dimethyl b-Cyclodextrin.
    • T. Ooya, D. Inoue, H. S. Choi, Y. Kobayashi, S. Loethen, D. H. Thompson*, Y. H. Ko, K. Kim*, N. Yui*
    • Organic Letters, 8, 3159-3162 (2006).
  47. One-Pot Synthesis of a Polyrotaxane via Selective Threading of a PEI-b-PEG-b-PEI Copolymer.
    • H. S. Choi, T. Ooya, N. Yui*
    • Macromolecular Bioscience, 6 , 420-424 (2006).
  48. Biocleavable Polyrotaxane-Plasmid DNA Polyplex for Enhanced Gene Delivery.
    • T. Ooya, H. S. Choi, A. Yamashita, N. Yui*, Y. Sugaya, A. Kano, A. Maruyama, H. Akita, K. Kogure, R. Ito, H. Harashima*
    • Journal of The American Chemical Society, 128, 3852-3853 (2006).
  49. Improved Cell Viability of Linear Polyethyleneimine Through g-Cyclodextrin Inclusion for Effective Gene Delivery.
    • A. Yamashita, H. S. Choi, T. Ooya, N. Yui*, H. Akita, K. Kogure, R. Ito, H. Harashima*
    • ChemPhysChem, 7, 297-302 (2006).
  50. Poly(ethylene glycol) Hydrogels Cross-linked by Hydrolyzable Polyrotaxane Containing Hydroxyapatite Particles as Scaffolds for Bone Regeneration
    • M. Fujimoto, M. Isobe, S. Yamaguchi*, T. Amagasa, A. Watanabe, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 16, 1611-1621 (2005).
  51. Sunflower-Shaped Cyclodextrin-Conjugated Poly(e-Lysine) Polyplex as a Controlled Intracellular Trafficking Device.
    • H. S. Choi, A. Yamashita, T. Ooya, N. Yui*, H. Akita, K. Kogure, R. Ito, H. Harashima*
    • ChemPhysChem, 6, 1986-1990 (2005).
  52. Synthesis of Poly(e-lysine)-Grafted Dextrans and Their pH- and Thermosensitive Hydrogelation with Cyclodextrins
    • H. S. Choi, K. Yamamoto, T. Ooya, N. Yui*
    • ChemPhysChem, 6, 1081-1086 (2005).
  53. Preparation of a-Cyclodextrin-terminated Polyrotaxane Consisting of b-Cyclodextrins and Pluronic as a Building Block of Biodegradable Network
    • T. Ooya, A. Ito, N. Yui*
    • Macromolecular Bioscience, 5, 379-383 (2005).
  54. Self-assembly of Cholesterol-Hydrotropic Dendrimer Conjugates into Micelle-like Structure: Preparation and Hydrotropic Solubilization of Paclitaxel.
    • T. Ooya, K. M. Huh, M. Saitoh, E. Tamiya, K. Park*
    • Science and Technology of Advanced Materials, 6 , 452-456 (2005).
  55. Temperature-controlled Erosion of Poly(N-isopropylacrylamide)-based Hydrogels Crosslinked by Methacrylate-introduced Hydrolyzable Polyrotaxane.
    • T. Ooya, M. Akutsu, Y. Kumashiro, N. Yui*
    • Science and Technology of Advanced Materials, 6, 447-451 (2005).
  56. Anticoagulant Supramolecular-structured Polymers: Synthesis and Anticoagulant Activity of Taurine-conjugated Carboxyethylester-polyrotaxanes.
    • Y. K. Joung, Y. Sengoku, T. Ooya, K. D. Park, N. Yui*
    • Science and Technology of Advanced Materials, 6, 484-490 (2005).
  57. pH-Triggered Changing in Assembling Properties of b-Cyclodextrin-conjugated Poly(e-lysine) Complexes.
    • H. S. Choi, T. Ooya, N. Yui*
    • Biomacromolecules, 6, 1200-1204 (2005).
  58. Rapid Binding of Concanavalin A and Mmaltose-polyrotaxane Conjugates due to Mobile Motion of a-Cyclodextrins Threaded onto a Poly(ethylene glycol).
    • T. Ooya, H. Utsunomiya, M. Eguchi, N. Yui*
    • Bioconjugate Chemistry, 16, 62-69 (2005).
  59. Novel Biodegradable Cholesterol-introduced Polyrotaxane Hydrogels for Cartilage Regeneration
    • W. Tachaboonyakiat, T. Furubayashi, M. Katoh, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 15,1389-1404 (2004)
  60. Structural Role of Guest Molecules in Rapid and Sensitive Supramolecular Assembling System based on b-Cyclodextrin-conjugated Poly(e-lysine).
    • H. S. Choi, A. Takahashi, T. Ooya, N. Yui*
    • Macromolecules, 37, 10036-10041 (2004).
  61. Block-Selective Polypseudorotaxane Formation via pH Variation.
    • S. C. Lee, H. S. Choi, T. Ooya, N. Yui*
    • Macromolecules, 37, 7464-7468 (2004).
  62. pH-Dependence of Polypseudorotaxane Formation between Cationic Linear Polyethyleneimine.
    • H. S. Choi, S. C. Lee, T. Ooya, S. Sasaki, M. Kurisawa, H. Uyama, N. Yui*
    • Macromolecules, 37, 6705-6710 (2004).
  63. Dextran Hydrogels Containing Poly(N-isopropylacrylamide) as Grafts and Cross-Linkers Exhibiting Enzymatic Regulation at Specific Temperature Range.
    • Y. Kumashiro, T. Ooya, N. Yui*
    • Macromolecular Rapid Communications, 25, 867-872 (2004).
  64. Effect of The Mobility of Ligands in Polyrotaxanes on Order Structure of Water Clusters.
    • H. Hirose, H. Sano*, G. Mizutani, M. Eguchi, T. Ooya, N. Yui*
    • Langmuir, 20, 2852-2854 (2004).
  65. Hydrotropic Dendrimers of Generations 4 and 5: Synthesis, Characterization, and Hydrotropic Solubilization of Paclitaxel.
    • T. Ooya, J. Lee, K. Park*
    • Bioconjugate Chemistry, 15, 1221-1229 (2004).
  66. Gelation Rate Modulation of an a-Cyclodextrin and Poly(ethylene glycol)-Grafted Hyaluronic acid Solution System by Inclusion Complexation in Microphase-Separated Structure
    • T. Nakama, T. Ooya, N. Yui*
    • Macromolecular Rapid Communications, 25, 739-742 (2004).
  67. pH-Triggered Assembling System Using Cooperative Binding Between Cyclodextrin-Conjugated Poly(e-lysine)s and Anionic Guest in Aqueous Media.
    • H. S. Choi, K. M. Huh, T. Ooya, N. Yui*
    • The Journal of Physical Chemistry B., 108, 7646-7650 (2004).
  68. Spontaneous Change of Physical State from Hydrogels to Crystalline Precipitates During Polypseudorotaxane Formation.
    • H. S. Choi, T. Ooya, S. Sasaki, N. Yui*, M. Kurisawa, H. Uyama, S. Kobayashi
    • ChemPhysChem, 5, 1431-1434 (2004).
  69. Sulfonated Poly(ethylene glycol) Containing Methacrylate Copolymer Surfaces; Preparation, Characterization and In Vitro Biocompatibility
    • K. D. Park, H. D. Park, H. J. Lee, Y. H. Kim, T. Ooya, N. Yui*
    • Macromolecular Research,12, 342-351 (2004).
  70. Temperature- and pH-Controlled Hydrogelation of Poly(ethylene glycol)-Grafted Hyaluronic Acid by Inclusion Complexation with a-Cyclodextrin
    • T. Nakama, T. Ooya, N. Yui*
    • Polymer Journal, 36, 338-344 (2004).
  71. Effects of Polyrotaxane Structure on Polyion Complexation with DNA
    • T. Ooya, A. Yamashita, M. Kurisawa, Y. Sugaya, A. Maruyama, N. Yui*
    • Science and Technology of Advanced Materials, 5, 363-369 (2004).
  72. Design of Polyrotaxanes as Supramolecular Conjugates for Cells and Tissues.
    • N. Yui*, T. Ooya
    • Journal of Artificial Organs, 7, 62-68 (2004).
  73. Supramolecular Hydrogel Formation Based on Inclusion Complexation Between Poly(ethylene glycol) Modified Chitosan and a-Cyclodextrin.
    • K. M. Huh, Y. W. Cho, H. Chung, I. C. Kwon, S. Y. Jeong, T. Ooya, W. K. Lee, S. Sasaki, N. Yui*
    • Macromolecular Bioscience, 4, 92-99 (2004).
  74. Controlling The Mechanism of Trypsin Inhibition by The Numbers of a-Cyclodextrins and Carboxyl Groups in Carboxyethylester-Polyrotaxanes.
    • M. Eguchi, T. Ooya, N. Yui*
    • Journal of Controlled Release, 96, 301-307 (2004).
  75. Control of Rapid Phase Transition Induced by Supramolecular Complexation of b-Cyclodextrin-Conjugated Poly(e-lysine) with a Specific Guest.
    • H. S. Choi, T. Ooya, S. Sasaki, N. Yui*
    • Macromolecules, 36, 5342-5347 (2003).
  76. Supramolecular Design for Multivalent Interaction: Maltose Mobility Along Polyrotaxane Enhanced Binding with Concanavalin A.
    • T. Ooya, M. Eguchi, N. Yui*
    • Journal of The American Chemical Society, 125, 13016-13017 (2003).
  77. Supramolecular Control of Ester Hydrolysis in Poly(ethylene glycol) Interlocked Hydrogels.
    • T. Ichi, T. Ooya, N. Yui*
    • Macromolecular Bioscience, 3, 373-380 (2003).
  78. Preparation of Porous Hydrolyzable Polyrotaxane Hydrogels and Their Erosion Behavior.
    • T. Ichi, W. K. Lee, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 14, 567-580 (2003).
  79. pH- and Thermo-Sensitive Supramolecular Assembling System: Rapidly Responsive Properties of b-Cyclodextrin-Conjugated Poly(e-lysine).
    • H. S. Choi, K. M. Huh, T. Ooya, N. Yui*
    • Journal of The American Chemical Society, 125, 6350-6351 (2003).
  80. Polyrotaxanes: Challenge to Multivalent Binding with Biological Receptors on Cell Surfaces.
    • N. Yui*, T. Ooya
    • Materials Science Forum, 426-432, 3243-3248 (2003).
  81. Preparation and Characterization of Polypseudorotaxanes Based on Biodegradable Poly(L-lactide)/Poly(ethylene glycol) Triblock Copolymers.
    • H. S. Choi, T. Ooya, Y. Ohya, T. Ouchi, N. Yui*
    • Macromolecules, 36, 9313-9318 (2003).
  82. Novel Poly(ethylene glycol) Scaffolds Crosslinked by Hydrolyzable Polyrotaxane for Cartilage Tissue Engineering.
    • W. K. Lee, T. Ichi, T. Ooya, T. Yamamoto, M. Kato, N. Yui*
    • Journal of Biomedical Materials Research, 67A, 1087-1092 (2003).
  83. In Vitro Biocompatibility Assessment of Sulfonated Polyrotaxanes-Immobilized Polyurethane Surfaces.
    • H. D. Park, W. K. Lee, T. Ooya, K. D. Park, Y. H. Kim, N. Yui*
    • Journal of Biomedical Materials Research, 66A, 596-604 (2003).
  84. Effects of Ethylene Glycol-based Graft, Star-shaped, and Dendritic Polymers on Solubilization and Controlled Release of Paclitaxel.
    • T. Ooya, J. Lee, K. Park*
    • Journal of Controlled Release, 93, 121-127 (2003).
  85. Hydrogels Having Tubular a-Cyclodexrin Structure: Effect of Nano-Tube Structure on Long Alkyl Chain Partitions.
    • T. Ooya, N. Kobayashi, T. Ichi, S. Sasaki, N. Yui*
    • Science and Technology of Advanced Materials, 4, 39-42 (2003).
  86. Preparation and Characterization of Plasmid DNA Network Via Both Triple Helix Formation and Photo-Crosslinking
    • Y. Kawabata, T. Ooya, N. Yui*
    • Science and Technology of Advanced Materials, 4, 43-46 (2003).
  87. Thermodynamic Analysis of Inclusion Complexation Between a-Cyclodextrin-Based Molecular Tube and Poly(ethylene oxide)-block-Poly(tetrahydrofuran)-block-Poly(ethylene oxide) Triblock Copolymer
    • T. Ikeda, W. K. Lee, T. Ooya, N. Yui*
    • Journal of Physical Chemistry B, 107, 14-19 (2003).
  88. Synthesis of a-Cyclodextrin-Conjugated Poly(e-lysine)s and Their Inclusion Complex.
    • K. M. Huh, H. Tomita, W. K. Lee, T. Ooya, N. Yui*
    • Macromolecular Rapid Communications, 23, 179-182 (2002).
  89. Fibloblast Adhesion and Proliferation on Poly(ethylene glycol) Hydrogels Cross-linked by Hydrolyzable Polyrotaxane.
    • J. Watanabe, T. Ooya, K. Nitta, K. D. Park, Y. H. Kim, N. Yui*
    • Biomaterials, 23, 4041-4048 (2002).
  90. pH Dependence of Inclusion Complexation Between Cationic Poly(e-lysine) and a-Cyclodextrin.
    • K. M. Huh, H. Tomita, T. Ooya, W. K. Lee, S. Sasaki, N. Yui*
    • Macromolecules, 35, 3775-3777 (2002).
  91. Enzymatic Degradation of Semi-IPN Hydrogels Based on N-Isopropylacrylamide and Dextran at a Specific Temperature Range.
    • Y. Kumashiro, T. Ooya, W. K. Lee, N. Yui*
    • Macromolecular Rapid Communications, 23, 407-410 (2002).
  92. Rapid Induction of Thermoreversible Hydrogel Formation Based on Poly(propylene glycol)-grafted Dextran Inclusion Complexes.
    • H. S. Choi, K. Kontani, K. M. Huh, S. Sasaki, T. Ooya, W. K. Lee, N. Yui*
    • Macromolecular Bioscience, 2, 298-303 (2002).
  93. Self-Assembled Plasmid DNA Network Prepared Through Both Triple-helix Formation and Streptavidin-Biotin Interaction.
    • Y. Kawabata, W. K. Lee, T. Ooya, N. Yui*
    • Macromolecular Bioscience, 2, 195-198 (2002).
  94. Synthesis of a-Cyclodextrin-Conjugated Poly(e-lysine)s and Their Inclusion Complex.
    • K. M. Huh, H. Tomita, W. K. Lee, T. Ooya, N. Yui*
    • Macromolecular Rapid Communications, 23, 179-182 (2002).
  95. Inhibitory Effect of Supramolecular Polyrotaxane-Dipeptide Conjugates on Digested Peptide Uptake via Intestinal Human Peptide Transporter.
    • N. Yui*, T. Ooya, T. Kawashima, Y. Saito, I. Tamai, Y. Sai, A. Tsuji*
    • Bioconjugate Chemistry, 13, 582-587 (2002).
  96. Multivalent Interactions between Biotin-Polyrotaxane Conjugates and Streptavidin as a Model of New Targeting for Transporters.
    • T. Ooya, N. Yui*
    • Journal of Controlled Release, 80, 219-228 (2002).
  97. Carboxyethylester-Polyrotaxanes as a New Calcium Chelating Polymer: Synthesis, Calcium Binding and Mechanism of Trypsin Inhibition.
    • T. Ooya, M. Eguchi, A. Ozaki, N. Yui*
    • International Journal of Pharmaceutics, 242, 47-54 (2002).
  98. Raman Scattering Study of Water Clusters Around Polyrotaxane and Pseudopolyrotaxane Supramolecular Assembly.
    • H. Sano*, T. Ichi, Y. Kumashiro, H. Kontani, T. Ooya, N. Yui*, G. Mizutani
    • Spectrochimica Acta A, 59, 285-289 (2002).
  99. Anticoagulant Activity of Sulfonated Polyrotaxanes as Blood Compatible Materials.
    • H. D. Park, W. K. Lee, T. Ooya, K. D. Park, Y. H. Kim, N. Yui*
    • Journal of Biomedical Materials Research, 60, 186-190 (2002).
  100. Synthesis and Characterization of Nitric Oxide Generative Polyrotaxane.
    • W. K. Lee, J. Kobayashi, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 13, 1152-1161 (2002).
  101. Supramolecular-Structured Hydrogel Showing a Reversible Phase Transition by Inclusion Complexation Between Poly(ethylene glycol) Grafted Dextran and a-Cyclodextrin.
    • K. M. Huh, T. Ooya, W. K. Lee, S. Sasaki, I. C. Kwon, S. Y. Jeong, N. Yui*
    • Macromolecules, 34, 8657-8662 (2001).
  102. Transience in Polyion Complexation between Nicotinamide-Modified Dextran and Carboxymethyl Dextran During Enzymatic Degradation of Dextran.
    • W. Kamimura, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 12, 1109-1122 (2001).
  103. Polymer Inclusion Complex Consisting of Poly(e-lysine) and a-Cyclodextrin.
    • K. M. Huh, T. Ooya, N. Yui*
    • Macromolecules, 34, 2402-2404 (2001).
  104. Study on The Solution Properties of Thermo-Responsive Polyrotaxanes with Different Number of Cyclic Molecules.
    • T. Ikeda, N. Watabe, T. Ooya, N. Yui*
    • Macromolecular Chemistry and Physics, 202, 1338-1344 (2001).
  105. Supramolecular Network Through Inclusion Complexation of a-CD-Based Molecular Tube.
    • T. Ikeda, T. Ooya, N. Yui*
    • Macromolecular Rapid Communications, 21, 1257-1261 (2001).
  106. Synthesis of Polyrotaxane-Biotin Conjugates and Surface Plasmon Resonance Analysis of Streptavidin Recognition.
    • T. Ooya, T. Kawashima, N. Yui*
    • Biotechnology and Bioprocess Engineering, 6, 293-300 (2001).
  107. Modulatory Factors on Temperature-Synchronized Degradation of Dextran Grafted with Thermo-Responsive Polymer and Its Hydrogels.
    • Y. Kumashiro, K. M. Huh, T. Ooya, N. Yui*
    • Biomacromolecules, 2, 874-879 (2001).
  108. New Synthetic Route for Dextran Graft Copolymers Containing Thermo-Responsive Polymers.
    • K. M. Huh, Y. Kumashio, T. Ooya, N. Yui*
    • Polymer Journal, 33, 108-111 (2001).
  109. Thermodynamic Analysis on Inclusion Complexation Between a-Cyclodextrin-Based Molecular Tube and Sodium Alkyl Sulfonate.
    • T. Ikeda, E. Hirota, T. Ooya, N. Yui* 
    • Langmuir,17, 234-238 (2001).
  110. Enhanced Accessibility of Peptide Substrate Toward a Membrane-Bound Metalloexopeptidase by Supramolecular Structure of Polyrotaxane.
    • T. Ooya, M. Eguchi, N, Yui*
    • Biomacromolecules, 2, 200-203 (2001).
  111. Controllable Erosion Time and Profile in Poly(ethylene glycol) Hydrogels by Supramolecular Structure of Hydrolyzable Polyrotaxane.
    • T. Ichi, J. Watanabe, T. Ooya, N. Yui*
    • Biomacromolecules, 2, 204-210 (2001).
  112. Preparation and Characterization of PEG Hydrogels Crosslinked by Hydrolyzable Polyrotaxane.
    • J. Watanabe, T. Ooya, K. D. Park, Y. H. Kim, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 11, 1333-1345 (2000).
  113. Synthesis and Characterization of an Oligopeptide-Terminated Polyrotaxane as a Drug Carrier.
    • T. Ooya, K. Arizono, N. Yui*
    • Polymers for Advanced Technology, 11, 642-651 (2000).
  114. Inclusion Complexation of Fractionated a-Cyclodextrin Molecular Tube with Sodium Dodecyl Sulfate
    • T. Ikeda, T. Ooya, N. Yui*
    • Polymers for Advanced Technology, 11, 830-836 (2000).
  115. Self-Complex Formation of Nicotineamide-Modified Dextrans with Carboxymethyl Dextran Using their Degradation Products.
    • W. Kamimura, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 11, 747-765 (2000).
  116. Synthesis and Characterization of Dextran Grafted with Poly (N-Isopropylacrylamide-co-Dimethylacrylamide).
    • K. M. Huh, J. Hashi, T. Ooya, N. Yui*
    • Macromolecular Chemistry and Physics, 201, 613-619 (2000).
  117. Feasibility Study of Hydrolyzable Polyrotaxanes Aiming at Implantable Materials
    • J. Watanabe, T. Ooya, N. Yui*
    • Journal of Artificial Organs, 3, 136-142 (2000).
  118. Pulsatile Peptide Release from Multi-layered Hydrogel Formulations Consisting of Poly(ethylene glycol)-Grafted and Ungrafted Dextrans.
    • K. Moriyama, T. Ooya, N. Yui
    • Journal of Biomaterials Science, Polymer Edition, 10, 1251-1264 (1999).
  119. Effect of Acetylation of Biodegradable Polyrotaxanes on Its Supramolecular Dissociation via Terminal Ester Hydrolysis.
    • J. Watanabe, T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 10, 1275-1288 (1999).
  120. Thermally-Responsive Properties of a Polyrotaxane Consisting of b-Cyclodextrins and Poly(ethylene glycol)-Poly(propylene glycol) Triblock-Copolymer.
    • H. Fujita, T. Ooya, N. Yui*
    • Polymer Journal, 31, 1099-1104 (1999).
  121. Thermally Induced Localization of Cyclodextrins in a Polyrotaxane Consisting of b-Cyclodextrins and Poly(ethylene glycol)-Poly(propylene glycol) Triblock-Copolymer.
    • H. Fujita, T. Ooya, N. Yui*
    • Macromolecules, 32, 2534-2541 (1999).
  122. Regulation of Polypseudorotaxane Formation Between a-Cyclodextrin and Azobenzene-Terminated Poly(ethylene glycol).
    • T. Ikeda, T. Ooya, N. Yui*
    • Polymer Journal, 31, 658-663 (1999).
  123. Synthesis and Characterization of a Polyrotaxane Consisting of b-Cyclodextrins and Poly(ethylene glycol)-Poly(propylene glycol) Triblock-Copolymer.
    • H. Fujita, T. Ooya, N. Yui*
    • Macromolecular Chemistry and Physics, 200, 706-719 (1999).
  124. Synthesis of a Theophylline-Polyrotaxane Conjugate and Its Drug Release via Supramolecular Dissociation.
    • T. Ooya, N. Yui*
    • Journal of Controlled Release, 58, 251-269 (1999).
  125. Hyaluronic Acid Grafted with Poly(ethylene glycol) as a Novel Peptide Formulation.
    • K. Moriyama, T. Ooya, N. Yui*
    • Journal of Controlled Release, 59, 77-86 (1999).
  126. Supramolecular Dissociation of Biodegradable Polyrotaxanes by Terminal Hydrolysis.
    • T. Ooya, N. Yui*
    • Macromolecular Chemistry and Physics, 199, 2311-2320 (1998).
  127. Preparation and Characterization of a Polyrotaxane with Non-Enzymatically Hydrolyzable Stoppers.
    • J. Watanabe, T. Ooya, N. Yui*
    • Chemistry Letters, 1998, 1031-1032.
  128. Regulation of Intracellular Metabolism by Biodegradable Polyrotaxanes.
    • T. Ooya, T. Kumeno, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 9, 313-326 (1998).
  129. Effect of Bbiodegradable Polyrotaxane on Platelet Activation.
    • N. Yui*, T. Ooya, T. Kumeno
    • Bioconjugate Chemistry, 9, 118-125 (1998).
  130. Synthesis and Characterization of Biodegradable Polyrotaxane as a Novel Supramolecular-Structured Drug Carrier.
    • T. Ooya, N. Yui*
    • Journal of Biomaterials Science, Polymer Edition, 8, 437-456 (1997).
  131. Interaction of Polyrotaxane with Hairless Rat stratum Corneum.
    • W. Kamimura, T. Ooya, N. Yui*
    • Journal of Controlled Release, 44, 295-299 (1997).
  132. ポリロタキサン構造からなる超分子集合体と皮膚角質層との相互作用およびそのインドメタシン透過性への影響
    • 大谷 亨、菅原広行、由井伸彦*
    • Drug Delivery Systems(日本DDS学会誌)12(2), 89-94 (1997).  
  133. Thermally Switchable Polyrotaxane as a Model of Stimuli-Responsive Supramolecules for Nano-scale Devices.
    • H. Fujita, T. Ooya, M. Kurisawa, H. Mori, M. Terano, N. Yui*
    • Macromolecular Rapid Communications, 17, 509-515 (1996).
  134. Synthesis of a Biodegradable Polymeric Supramolecular Assembly for Drug Delivery.
    • T. Ooya, H. Mori, M. Terano, N. Yui*
    • Macromolecular Rapid Communications, 16, 259-263 (1995).

総説・解説

  1. ポリグリセロール型デンドリマーの機能評価と利用
    • 杉本洋輔、大谷 亨
    • オレオサイエンス、17 211-216 (2017).
  2. ポリグリセロールデンドリマーおよびデンドロンの微粒子としての特徴
    • 大谷 亨
    • バイオマテリアル(日本バイオマテリアル学会誌)33 284-287 (2015).
  3. ポリグリセロール枝分かれ環境が及ぼす分子間相互作用制御
    • 大谷 亨
    • 科学と工業, 88 2-8 (2015).
  4. ポリグリセロールデンドリマーの薬剤学的応用、
    • 大谷 亨
    • バイオマテリアル(日本バイオマテリアル学会誌)27(1) 32-37 (2009).
  5. モレキュラーインプリンティング -最近の展開ー,
    • 大谷 亨、竹内俊文、
    • 高分子 , 57 (11), 903-911 (2008)
  6. 学会印象記「35th Annual Meeting & Exposition of the Controlled Release Society」
    • 大谷 亨
    • Drug Delivery Systems(日本DDS学会誌)23(5), 585-587 (2008).
  7. シクロデキストリンと高分子の串刺し構造による標的指向性向上へのアプローチ
    • 大谷 亨、由井伸彦、
    • バイオインダストリー24(3), 28-34 (2007).
  8. 人工臓器—最近の進歩・人工材料(有機)
    • 大谷 亨、由井伸彦
    • 人工臓器、35(3), 356-358 (2007).
  9. ポリロタキサン構造を有するバイオマテリアルの合成と応用
    • 大谷 亨
    • バイオマテリアルー生体材料24(3), 209-215 (2006).
  10. 学会印象記 「2004年夏・欧州学会報告: World Polymer Congress MACRO 2004 (40th International Symposium on Macromolecules sponsored by the International Union of Pure and Applied Chemistry (IUPAC)), 43rd Microsymposium Polymer Biomaterials: Biomimetic and Bioanalogous System, Inst. Macromol. Chem., Academy of Sciences of The CzechRepublic, Prague, Czech Republic」
    • 大谷 亨
    • バイオマテリアル(日本バイオマテリアル学会誌)22(6) 432 (2004).
  11. 新設大学・新研究室からの思想と経験
    • 大谷 亨
    • 高分子(高分子学会誌)52(11), 850 (2003).
  12. 学会印象記 「Winter Symposium & 11th International Symposium on Recent Advances in Drug Delivery Systems」
    • 大谷 亨
    • Drug Delivery Systems(日本DDS学会誌)18(4), 403-404 (2003).
  13. 学会印象記 「A Symposium in honor of the 70th birthday of Professor Allan S. Hoffman: Gels, Genes, Grafts & Giants Transitioning Biomaterials in the 21st Century」
    • 大谷 亨
    • バイオマテリアル(日本バイオマテリアル学会誌)21(3), 234-235 (2003).
  14. Book Review 「Dendrimers and Other Dendritic Polymers. Jean M. J. Fréchet and Donald A. Tomalia, Eds., John Wiley & Sons, Inc., 605 Third Avenue, New York, NY 10158-0012, 2001, 647 pp., illustrations, $225.00.」
    • T. Ooya
    • Pharmaceutical Research, 19 (12), 1921 ( 2002)
  15. 生体との多価相互作用を目指した生体内分解性ポリロタキサンの設計
    • 大谷 亨,江口 優,由井伸彦
    • 高分子論文集,59, 734-741(2002).
  16. ポリロタキサン型超分子構造システムの医療への応用
    • 大谷 亨,由井伸彦
    • 医学のあゆみ, 199, 783-784 (2001).
  17. 分子認識能を有するポリロタキサン
    • 大谷 亨
    • 高分子, 50, 456 (2001).
  18. ポリロタキサン構造に着目した医用材料設計
    • 由井伸彦、大谷 亨
    • 未来材料, 1, 26-32 (2001).
  19. 超分子構造を有する生医学高分子材料の分子設計とインテリジェント機能
    • 由井伸彦、大谷 亨
    • 化学と教育, 48, 728-731 (2000).
  20. 超分子構造を利用した新規アクチュエーター用材料の研究
    • 池田太一、藤田広明、大谷 亨、由井伸彦
    • 高分子加工, 49, 307-312 (2000).
  21. シクロデキストリンの超分子化を利用した高分子機能
    • 由井伸彦、大谷 亨
    • 日本油化学協会誌, 49, 471-478 (2000).
  22. 組織工学材料を目指した生分解性ポリロタキサンの設計
    • 渡邊順司、大谷 亨、由井伸彦
    • 高分子加工, 48, 98-104 (1999).
  23. 刺激応答型ポリロタキサン設計 ―超分子の新展開
    • 大谷 亨、藤田広明、由井伸彦
    • 表面, 37, 232-239 (1999).
  24. Polyrotaxanes; Synthesis, Structure and Potential in Drug Delivery.
    • T. Ooya, N. Yui
    • Critical Reviews in Therapeutic Drug Carrier System, 16, 289-330 (1999).
  25. Biodegradable Polyrotaxanes As a Drug Carrier.
    • T. Ooya, N. Yui
    • s.t.p. Pharma. Sci., 9, 129-138 (1999).  IF =??, 引用回数 = 6
  26. 生体内分解性超分子
    • 大谷 亨、由井伸彦
    • 機能材料, 18, 56-67 (1998).
  27. 時間制御型DDSを目指した生体内分解性高分子
    • 大谷 亨、由井伸彦
    • バイオサイエンスとインダストリー 54, 25-28 (1996).

著書

  1. モレキュラーインプリント法による人工酵素
    • 竹内俊文、大谷 亨
    • (監修:小宮山 眞)酵素利用技術大系~基礎・解析から改変・高機能化・産業利用まで~ (株)エヌ・ティー・エス、2010, pp376-386
  2. 分子インプリンティングのバイオ応用
    • 竹内俊文、大谷 亨
    • (編集:有賀克彦)ナノ空間材料の創製と応用、フロンティア出版、東京、2009, pp336-342
  3. ポリロタキサン基盤材料
    • 大谷 亨
    • in: 次世代医療のための高分子材料工学、監修 秋吉一成,岸田晶夫、シーエムシー, 2008, pp.24-32
  4. 細胞工学のためのマイクロ・ナノスケールでの細胞環境制御
    • 診断・治療に向けた標的指向性パーフルオロカーボンナノ微粒子
    • 大谷 亨
    • 翻訳:ナノバイオテクノロジー ―未来を開く概念と応用―、監訳 丸山 厚、NTS, 2008, pp.311-327, 328-346.
  5. Hydrotropic polymer micelles for cancer therapeutics
    • S. C. Lee, T. Ooya, K. M. Huh, K. Park
    • in: Nanotechnology for Cancer Therapy, Editor(s): Amiji, Mansoor M., CRC Press, 2006.Dec, pp. 385-408
  6. Polymeric delivery systems for poorly soluble drugs
    • K. M. Huh, S. C. Lee, T. Ooya, K. Park
    • in: Encyclopedia of Pharmaceutical Technology Second Edition, ed by James Swarbrick, Marcel Dekker, NY, 2006, pp.2913-2924.
  7. Hydrotropic nanocarriers for poorly soluble drugs
    • T. Ooya, S. C. Lee, K. M. Huh, K. Park
    • in: Nanocarrier Technologies: Frontiers of Nanotherapy, Mozafari, M. Reza, Ed., Springer, Netherlands, 2006, pp.51-73.
  8. Biochemical and Physical Stimuli-triggered Cyclodextrin Release From Biodegradable Polyrotaxanes and Those Hydrogels
    • T. Ooya
    • in: Cyclodextrin Materials Photochemistry, Photophysics, and Photobiology, ed by Abderrazzak Douhal, Elsevier, 2006, pp.305-318.
  9. Biofunctional polyrotaxanes for enhancing biomolecular interactions
    • T. Ooya, N. Yui
    • in: The MML Series volume 7: Smart Nano and Microparticles, Kentus Books, UK, 2006, pp. 231-248.
  10. Polymer solution properties, polymer networks, micelles, dendrimers, hydrogels
    • T. Ooya, K. Park
    • in: Biomaterial for Delivery and Targeting of Proteins and Nucleic Acids ed by Ram I. Mahato, CRC, Boca Raton, 2005, pp.95-118
  11. Fast sliding motion of supramolecular assembly
    • N. Yui, T. Ooya
    • in: Reflexive Polymers and Hydrogels: Understanding and Designing Fast-Responsive Polymeric Systems, eds. by N. Yui, K. Park, R. J. Mrsny, CRC, Boca Raton, 2004, pp. 259-281.
  12. 多重刺激応答ヒドロゲルの創製 
    • 大谷 亨
    • (監修:石原一彦)ナノバイオエンジニアリングマテリアル、フロンティア出版、東京、2004, pp336-342
  13. Biodegradable polymers
    • N. Yui, T. Ooya
    • in: Supramolecular Design for Biological Applications, ed. by N. Yui, CRC, Boca Raton, 2002, pp169-189.
  14. Biodegradable polyrotaxanes aiming at biomedical and pharmaceutical applications
    • T. Ooya, N. Yui
    • in: Biomedical Polymers and Polymer Therapeutics, edited by E. Cheiellini, J. Sunamoto, C. Migliaresi, R. M. Ottenbrite, D. Cohn, Kluwer Academic / Plemun Publishers, New York, 2001, pp.75-90
  15. 新しい生分解性高分子による薬物送達システム
    • 由井伸彦、大谷 亨
    • バイオミメティックスハンドブック(長田義仁:編集)(2000) エヌ・ティー・エス、東京、pp803-812                              
  16. Design of polyrotaxane-based hydrolyzable materials for tissue engineering
    • J. Watanabe, T. Ooya, K.D.Park, Y. H. Kim, N. Yui
    • in: Biomaterials and Drug Delivery toward New Millennium, ed. by K. D. Park, I. C. Kwon, N. Yui, A. Y. Jeong, K. Park, Han Rim Won Publishing Co., Seoul, 2000, pp. 565-577.
  17. Solution property of a polyrotaxane in relation to stimuli-responsive movement of b-cyclodextrins
    • H. Fujita, T. Ooya, N. Yui
    • in: Precision Polymers and Nano-Organized Systems, ed. by T. Kunitake, S. Nakahama, S. Takahashi, N. Toshima, Kodansha Scientific, Tokyo, 2000, p.155-158.
  18. Supramolecular-structured polymers for drug delivery
    • T. Ooya, N. Yui
    • in: Controlled Drug Delivery: Designing Technologies for the Future, ed. by K. Park, ACS Symposium Series No. 752, ACS, Washington DC, 2000,pp. 375-384.
  19. 生体内分解性超分子
    • 由井伸彦、大谷 亨
    • 機能性超分子の設計と将来展望(緒方直哉、寺野 稔、由井伸彦:監修)(1998) シー・エムー・シー、東京、pp167-180.
  20. Stimuli-responsive properties of polyrotaxanes consisting of b-cyclodextrins and hydrophilic-hydrophobic block-copolymer
    • H. Fujita, T. Ooya, M. Kurisawa, N. Yui,
    • in: Advances in Polymeric Biomaterials Science, eds. by T. Akaike, T. Okano, M. Akashi, M. Terano, N. Yui, pp 649-656, CMC, Tokyo (1997).
  21. Biodegradable polyrotaxanes as advanced biomaterials
    • T. Ooya, N. Yui
    • in: Advances in Polymeric Biomaterials Science, eds. by T. Akaike, T. Okano, M. Akashi, M. Terano, N. Yui, pp 283-308, CMC, Tokyo (1997) .
  22. Novel design of supramolecular-structured biodegradable polymer for temporal drug delivery
    • N. Yui, T. Ooya
    • in: Advances in Biomedical Polymers in Biomedical Engineering and Drug Delivery Systems, eds by T. Okano, N. Ogata, J. Feijen, S. W. Kim, Springer, Tokyo, 1996, p.333-334.

招待講演・依頼講演

  1. ポリグリセロールデンドリマー、ハイパーブランチポリグリセロールおよびこれら誘導体の水和と機能
    • 大谷 亨
    • 第26回日本MRS年次大会、2016年 12月, 横浜
  2. Combination of poly(ethylene glycol) and hyaluronic acid for insulin delivery
    • T. Ooya
    • 2016 Annual Meeting of The Korean Society For Biotechnology and Bioengineering (KSBB), (Gwanju (Korea)),Oct. 13-14. 2016.
  3. 水性二相分離現象を利用した成長因子の放出制御と血管新生への応用
    • 大谷 亨
    • 日本歯科理工学会 近畿・中四国支部地方セミナー、2016年 8月, 大阪歯科大学
  4. ヒアルロン酸とポリエチレングリコールを組み合わせたプロテインデリバリーの可能性
    • 大谷 亨
    • 高分子学会九州支部フォーラム~高分子科学と医療技術の交差点~ 、2016年 1月, 熊本大学
  5. ポリグリセロールデンドリマーのDDSへの応用可能性
    • 大谷 亨
    • 平成27年度第2回「メディショナルナノテク研究会」、2015年 9月, 大阪大学
  6. 新奇バイオマテリアル開発の発想: 基礎と企業化出口の両面をみる
    • 大谷 亨
    • はりま産学交流会,2015年 6月, 姫路
  7. Tocopherol-based drug carriers: combination of antioxdation and anticancer drugs
    • T. Ooya
    • The 2015 International Symposium for Advanced Materials Research (ISAMR 2015), (台北市、中華民国), Aug. 16-20. 2015.
  8. 低枝分かれグリセロールとタンパク質・細胞との相互作用:極性変化に伴うDDS応用への可能性、
    • 大谷 亨
    • 平成26年度第2回「メディショナルナノテク研究会」、2014年 9月, 神戸薬科大学
  9. Dendritic glycerols for application to drug delivery and biosensors
    • T. Ooya
    • The 2015 Symposium for the Promotion of Applied Research Collaboration in Asia (SPARCA 2015), (台北市、中華民国), February 8-11. 2015.
  10. Cyclodextin-based Crosslinked Polymers for Molecular Recognition,
    • T. Ooya
    • The 7th Asian Cyclodextrin Symposium, (バンコク市、タイ王国),November 27-29. 2013.
  11. Nitrogen-free Dendritic Biomaterials: From Host-Guest Chemistry to Biomolecular Interactions
    • T. Ooya
    • The 6th International Symposium on Intelligent Drug Delivery Systems, (ソウル市、韓国,), March, 2012
  12. 超分子を利用した生体反応の蛍光検出の試み、
    • 大谷 亨
    • 第24回生体機能関連化学シンポジウム若手フォーラム、2009年 9月, 九州大学
  13. 湿式微粒化装置を利用したソフトマテリアルの改質
    • 大谷 亨
    • 「ナノ構造・物性」第一回研究会(神戸大学)2009年 1月
  14. Polyglycerol dendrimers as a new biocompatible material
    • T. Ooya
    • The 2nd International Workshop on Future Molecular Systems, (テジョン市、韓国), May, 2007
  15. Multivalent molecular recognition based on molecular motion of cyclodextrins in polyrotaxanes
    • T. Ooya
    • The Third China-Japan-Korea (Asia3) Foresight Joint Symposium on Gene Therapy(テジョン市、韓国), May, 2007
  16. デンドリマーのナノ構造に基づいた薬物溶解と放出制御へのアプローチ
    • 大谷 亨
    • 第12回創剤フォーラム若手シンポジウム(横浜市)2006年 11月
  17. ポリロタキサンとデンドリマーのナノ構造が生化学的機能へ及ぼす影響
    • 大谷 亨
    • 第17回バイオマテリアル若手研究会(東京都)2006年 11月
  18. 薬物・バイオ領域を指向したポリグリセロールデンドリマーのナノサイズ効果
    • 大谷 亨
    • 第67回関西地区高分子若手研究会(大阪大学)2006年 11月
  19. Role of dendrimer and polyrotaxane structure on biomaterials design, seminar at medicinal science division
    • T. Ooya
    • 忠南国立大学、韓国科学技術研究院(テジョン市、韓国), Sep., 2006
  20. Structural effects of nano-biomaterials on drug delivery, tissue engineering, and diagnosis
    • T. Ooya
    • 第4回ナノ構造医用材料国際会議(ソウル市, 韓国), Sep., 2006
  21. シクロデキストリン誘導体の超分子形成による生体分子間相互作用制御
    • 大谷 亨
    • 第55回高分子学会年次大会(若手招待講演名古屋市)2006年 5月
  22. Degradation-triggered Cyclodextrin Release from Biodegradable Polyrotaxanes for Biomedical Applications
    • T. Ooya
    • The 3rd Asian Cyclodextrin Conference (ACC2005), Tianjin, China, May 8-12, 2005
  23. Modulated biomolecular recognition based on nano-sized association and mobility of supramolecular conjugates
    • T. Ooya, M. Eguchi, K. Machida, N. Yui
    • JAIST International Symposium: Nanotechnology 2003, Ishikawa, Japan, September 12-13, 2003.
  24. Hydrotropic polymers, hydrogels and dendrimers for solubility enhancement of poorly soluble drugs
    • T. Ooya, K. Park
    • The Winter Symposium and 11th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, USA, March 3-6, 2003.
  25. Supramolecular design as biomaterials: Ligand mobility along polyrotaxane backbone contributes to enhancing multivalent interaction with biological systems
    • T. Ooya
    • Advanced Polymeric Materials and Technology (APMT-2003), Gyeongju, March 15, 2003.
  26. Architectural functions of polyrotaxanes consisting of cyclodextrins and poly(ethylene glycol) as Biomaterials
    • T. Ooya
    • 2000 Spring Meeting of The Korean Society for Biomaterials, YonseiUniversity, Seoul, March 18, 2000.

特許

  1. PCT/JP2016/070704
    薬物徐放性担体及びその製造方法
    発明者:権 英淑 , 大谷 亨, 蒋 融融, 神山 文男 、
    出願者:コズメディ製薬(株)
  2. 特開2009-269982
    • 擬ポリロタキサンの調製法
    • 発明者:大谷 亨、原島謙一、尾塩岳治
    • 出願者:富山県、㈱スギノマシン
    • (特許認定になりました)特許権者: 株式会社スギノマシン, 富山県, 特許第5201550号, 特許登録日: 2013年2月22日
  3. 特開2009-114094
    • ポリグリセロール含有経皮吸収促進剤
    • 発明者:中島範行、大谷 亨、濱田昌弘、加藤達久、
    • 出願者:テイカ製薬(株)、富山県、
  4. 特開2009-051900
    • ポリグリセロールデンドリマーの精製法
    • 発明者:大谷 亨
    • 出願者:富山県
    • (特許認定になりました)特許権者: 富山県, 特許第5366168号, 特許登録日: 2013年9月20日
  5. 特開2008-100941
    • ポリグリセロールデンドリマーの3次元架橋物及び3次元架橋方法、並びにこれを用いたヒドロゲル、薬物送達システム
    • 発明者:大谷 亨
    • 出願者:富山県
  6. 特開2007−244601
    • 心筋用パッド
    • 発明者:飯野賢治、渡邊 剛、由井伸彦、大谷 亨、河端良二
    • 出願者:国立大学法人金沢大学、国立大学法人北陸先端科学技術大学院大学
  7. 特開2006−291097
    • ヒアルロン酸誘導体、およびその製造法
    • 発明者:由井伸彦、大谷 亨、吉田周平、河端良二、名嘉真剛
    • 出願者:由井伸彦、村上弘一、チッソ株式会社
  8. 特開2006−94799
    • 細胞剥離剤及び細胞シート剥離方法
    • 発明者:ワンペンテチャブンヤキャート、加藤雅一、大谷 亨、由井伸彦
    • 出願者:科学技術振興機構、株式会社ジャパンティッシュエンジニアリング、国立大学法人北陸先端科学技術大学院大学
  9. 特開2005-239687
    • 嚢胞内投与薬
    • 発明者:由井伸彦、村上弘一、大谷 亨、名嘉真剛、佐藤郁夫、河端良二、
    • 出願者:由井伸彦、村上弘一、チッソ株式会社
  10. 特開2005−143920
    • ポリロタキサンとそのヒドロゲル並びに組織再生用基材と軟骨細胞の培養方法
    • 発明者:ワンペンテチャブンヤキャート、古林呂之、加藤雅一、大谷 亨、由井伸彦、出願者:科学技術振興機構、株式会社ジャパンティッシュエンジニアリング、国立大学法人北陸先端科学技術大学院大学
  11. 特開2005-139080
    • 複合刺激応答材料
    • 発明者:由井伸彦、大谷 亨
    • 出願者:チッソ株式会社
  12. 特開2005-053974
    • 多糖架橋体及びその製造法
    • 発明者:由井伸彦、大谷 亨、名嘉真剛、河端良二
    • 出願者:チッソ株式会社
  13. 特開2004-323454
    • 薬剤
    • 発明者:由井伸彦、村上弘一、大谷 亨、名嘉真剛、佐藤郁夫、河端良二
    • 出願者:チッソ株式会社、由井伸彦、村上弘一
  14. 特開2004-323453
    • 分解性ゲル及びその製造法
    • 発明者:由井伸彦、大谷 亨、名嘉真剛、佐藤郁夫、河端良二
    • 出願者:チッソ株式会社、由井伸彦
  15. 特開2004-123785
    • n-アルカノイル化ヒアルロン酸もしくはその塩およびその製造法
    • 発明者:由井伸彦、大谷 亨、名嘉真 剛
    • 出願者:由井伸彦、チッソ株式会社
  16. 特開2004-27183
    • 多価結合性分子集合体、捕捉剤、薬剤基材、カルシウムキレート剤、及び、薬剤補助剤
    • 発明者:由井 伸彦、丸山 厚、大谷 亨
    • 出願者:由井 伸彦
  17. 特開2003-327545
    • 捕捉物キャリア、捕捉物キャリア複合体、捕捉物導入方法及び吸着体
    • 発明者:丸山 厚、由井 伸彦、大谷 亨
    • 出願者:丸山 厚、由井 伸彦
  18. 特願2003-387287
    • ポリロタキサンとそのヒドロゲル並びに組織再生用基材と軟骨細胞の培養方法
    • 発明者:ワンペンテチャブンヤキャート、古林呂之、加藤雅一、大谷 亨、由井伸彦
    • 出願者:科学技術振興機構、株式会社ジャパンティッシュエンジニアリング、北陸先端科学技術大学院大学長
  19. 特開2003-250546
    • 刺激応答型DNA組織体
    • 発明者:由井 伸彦、大谷 亨
    • 出願者:科学技術振興事業団
  20. 特開2003-246882
    • 生分解性包接組織体
    • 発明者:由井伸彦、大谷 亨
    • 出願者:チッソ株式会社
  21. 特開2003-2843
    • 組織特異的トランスポーター阻害剤
    • 発明者:辻 彰、玉井 郁己、崔 吉道、由井 伸彦、大谷 亨、宮本 賢一
    • 出願者:科学技術振興事業団
  22. 特開2002-356501
    • 化学修飾ヒアルロン酸またはその塩、およびその製造方法
    • 発明者:由井伸彦、大谷 亨、佐藤郁夫、出願者:チッソ株式会社、由井伸彦
  23. 特開2002-356447
    • 婦人科疾患治療剤
    • 発明者:由井伸彦、村上弘一、大谷 亨、佐藤郁夫、出願者:チッソ株式会社、由井伸彦、村上弘一
  24. 特開2002-37884
    • ポリロタキサンおよびε-ポリリジンの製造方法
    • 発明者:由井伸彦、大谷 亨、平木 純、荒川 健司、出願者:チッソ株式会社
  25. 特開平11-319069
    • 超分子埋植材料
    • 発明者:由井伸彦,大谷 亨、出願者:科学技術振興財団