Publication

(As of April 15, 2021)

Original papers

  1. Meredith, S. A., Yoneda, T., Hancock, A. M., Connell, S. D., Evans, S. D., Morigaki, K., Adams, P. G. "Model lipid membranes assembled from natural plant thylakoids into 2-D microarray patterns as a platform to assess the organization and photophysics of light-harvesting proteins", Small, 17, 2006608 (2021)
  2. Odagaki, S.-I., Maekawa, S., Hayashi, F., Suzaki, T., Morigaki, K. "The effects of phospholipids and fatty acids on the oligomer formation of NAP-22", Neurosci. Lett. 736, 135288, (2020)
  3. Yoneda, T., Tanimoto, Y., Takagi, D., Morigaki, K. "Photosynthetic model membranes of natural plant thylakoid embedded in a patterned polymeric lipid bilayer", Langmuir 36 (21), 5863-5871, (2020)
  4. Kaneshige, Y., Hayashi, F., Morigaki, K., Tanimoto, Y., Yamashita, H., Fuji, M., Awazu, A. "Affinity of rhodopsin to raft enables the aligned oligomer formation from dimers: Coarse-grained molecular dynamics simulation of disk membranes", PLoS One 15 (2), e0226123, (2020)
  5. Tamura, F., Tanimoto, Y., Nagai, R., Hayashi, F., Morigaki, K. "Self-spreading of phospholipid bilayer in a patterned framework of polymeric bilayer", Langmuir 35 (45), 14696-14703, (2019)
  6. Nomura, K., Yamaguchi, T., Mori, S., Fujikawa, K., Nishiyama, K.-i., Shimanouchi, T., Tanimoto, Y., Morigaki, K., Shimamoto, K. "Alteration of membrane physicochemical properties by two factors for membrane protein integration", Biophys. J. 117 (1), 99-110, (2019)
  7. Hayashi, F., Saito, N., Tanimoto, Y., Okada, K., Morigaki, K., Seno, K., Maekawa, S. "Raftophilic rhodopsin clusters offer stochastic platforms for G protein signalling in retinal discs", Commun. Biol. 2 209, (2019)
  8. Tanabe, M., Ando, K., Komatsu, R., Morigaki, K. "Nanofluidic biosensor created by bonding patterned model cell membrane and silicone elastomer with silica nanoparticles", Small 14 (49), 1802804, (2018)
  9. Nishimura, T., Tamura, F., Kobayashi, S., Tanimoto, Y., Hayashi, F., Sudo, Y., Iwasaki, Y., Morigaki, K. "Hybrid model membrane combining micropatterned lipid bilayer and hydrophilic polymer brush", Langmuir 33 (23), 5752-5759, (2017)
  10. Kinoshita, M., Suzuki, K. G. N., Matsumori, N., Takada, M., Ano, H., Morigaki, K., Abe, M., Makino, A., Kobayashi, T., Hirosawa, K. M., Fujiwara, T., Kusumi, A., Murata, M. "Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs", J. Cell Biol. 216 (4), 1183-1204, (2017)
  11. Nomura, K., Tanimoto, Y., Hayashi, F., Harada, E., Shan, X.-Y., Shionyu, M., Hijikata, A., Shirai, T., Morigaki, K., Shimamoto, K. "The role of the Prod1 membrane anchor in newt limb regeneration", Angew. Chem. Int. Ed. 56 (1), 270-274, (2017)
  12. Ando, K., Tanabe, M., Morigaki, K. "Nanometric gap structure with fluid lipid bilayer for the selective transport and detection of biological molecules", Langmuir 32 (31), 7958-7964, (2016)
  13. Tanimoto, Y., Okada, K., Hayashi, F., Morigaki, K. "Evaluating the raftophilicity of rhodopsin photoreceptor in a patterned model membrane", Biophys. J. 109 (11), 2307-2316, (2015)
  14. Sasahara, K., Morigaki, K., Mori, Y. "Uptake of raft components into amyloid beta-peptide aggregates and membrane damage", Anal. Biochem. 481 (1), 18-26, (2015)
  15. Kuroda, K., Miyoshi, H., Fujii, S., Hirai, T., Takahara, A., Nakao, A., Iwasaki, Y., Morigaki, K., Ishihara, K., Yusa, S. "Poly(dimethylsiloxane) (PDMS) surface patterning by biocompatible photo-crosslinking block copolymers", RSC Adv. 5 (58), 46686-46693, (2015)
  16. Okada, F., Morigaki, K. "Micropatterned model membrane with quantitatively controlled separation of lipid phases", RSC Adv. 5 1507-1513, (2015)
  17. Sasahara, K., Morigaki, K., Shinya, K. "Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces", FEBS J. 281 (11), 2597-2612, (2014)
  18. Fujiwara, M., Shiokawa, K., Kubota, T., Morigaki, K. "Preparation of calcium carbonate microparticles containing organic fluorescent molecules from vaterite", Adv. Powder Technol. 25 (3), 1147-1154, (2014)
  19. Kanemura, E., Goto, T., Tatsu, Y., Imaishi, H., Morigaki, K. "Parallel assay of inkjet-printed cytochrome P450", Anal. Methods 6 (7), 2117-2124, (2014)
  20. Yamada, M., Imaishi, H., Morigaki, K. "Microarrays of phospholipid bilayers generated by inkjet-printing", Langmuir 29 (21), 6404-6408, (2013)
  21. Sasahara, K., Morigaki, K., Shinya, K. "Effects of membrane interaction and aggregation of amyloid b-peptide on lipid mobility and membrane domain structure", Phys. Chem. Chem. Phys. 15 (23), 8929-8939, (2013)
  22. Morigaki, K., Mizutani, K., Saito, M., Okazaki, T., Nakajima, Y., Tatsu, Y., Imaishi, H. "Surface functionalization of a polymeric lipid bilayer for coupling a model biological membrane with molecules, cells, and microstructures", Langmuir 29 (8), 2722-2730, (2013)
  23. Sasahara, K., Morigaki, K., Okazaki, T., Hamada, D. "Binding of islet amyloid polypeptide to supported lipid bilayers and amyloid aggregation at the membranes", Biochemistry 51 (35), 6908–6919, (2012)
  24. Watanabe, K., Miyazaki, R., Terakado, G., Okazaki, T., Morigaki, K., Kano, H. "Localized surface plasmon microscopy of submicron domain structures of mixed lipid bilayers", Biomed. Opt. Express 3 (9), 2012-2020, (2012)
  25. Morigaki, K., Kimura, S., Okada, K., Kawasaki, T., Kawasaki, K. "Formation of substrate supported membranes from mixtures of long and short chain phospholipids", Langmuir 28 (25), 9649−9655, (2012)
  26. Chang, G., Mori, Y., Mori, S., Irie, T., Nagai, H., Goto, T., Tatsu, Y., Imaishi, H., Morigaki, K. "Microarray of human P450 with an integrated oxygen sensing film for high-throughput detection of metabolic activities", Anal. Chem. 84 (12), 5292−5297, (2012)
  27. Morigaki, K., Mizutani, K., Kanemura, E., Tatsu, Y., Yumoto, N., Imaishi, H. "Photo-regulation of cytochrome P450 activity by using caged compound", Anal. Chem. 84 (1), 155-160, (2012)
  28. Nomura, K., Lintuluoto, M., Morigaki, K. "Hydration and temperature dependence of 13C and 1H NMR spectra of the DMPC phospholipid membrane and complete resonance assignment of its crystalline state", J. Phys. Chem. B 115 (50), 14991-15001, (2011)
  29. Inaba, T., Tatsu, Y., Morigaki, K. "Fusion of lipid vesicles with planar lipid bilayers induced by a combination of peptides", Langmuir 27 (20), 12515-12520, (2011)
  30. Tawa, K., Cui, X., Kintaka, K., Nishii, J., Morigaki, K. "Sensitive bioimaging in microfluidic channels on the plasmonic substrate: Application of an enhanced fluorescence based on the reverse coupling mode", J. Photochem. Photobiol., A 221 (3), 261-267, (2011)
  31. Chang, G., Morigaki, K., Tatsu, Y., Hikawa, T., Goto, T., Imaishi, H. "Vertically integrated human P450 and oxygen sensing film for the assays of P450 metabolic activities", Anal. Chem. 83 (8), 2956-2963, (2011)
  32. Fujiwara, M., Shiokawa, K., Araki, M., Ashitaka, N., Morigaki, K., Kubota, T., Nakahara, Y. "Encapsulation of proteins into CaCO3 by phase yransition from vaterite to calcite", Cryst. Growth Des. 10 (9), 4030-4037, (2010)
  33. Goto, T., Moriuchi, H., Fu, X., Ikegawa, T., Matsubara, T., Chang, G., Uno, T., Morigaki, K., Isshiki, K., Imaishi, H. "The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsolaren", Drug Metab. Dispos. 38 (12), 2110-2116, (2010)
  34. Chang, G., Tatsu, Y., Goto, T., Imaishi, H., Morigaki, K. "Glucose concentration determination based on silica sol-gel encapsulated glucose oxidase optical biosensor arrays", Talanta 83 (1), 61-65, (2010)
  35. Nakai, K., Morigaki, K., Iwasaki, Y. "Molecular recognition on fluidic lipid bilayer microarray corralled by well-defined polymer brushes", Soft Matter 6 (23), 5937-5943, (2010)
  36. Tawa, K., Morigaki, K. "In-situ imaging of micropatterned phospholipid membranes by surface plasmon fluorescence microscopy", Colloids Surf. B 81 447-451, (2010)
  37. Okazaki, T., Tatsu, Y., Morigaki, K. "Phase separation of lipid microdomains controlled by polymerized lipid bilayer matrices", Langmuir 26 (6), 4126-4129, (2010)
  38. Watanabe, K., Miyazaki, R., Terakado, G., Okazaki, T., Morigaki, K., Kano, H. "High resolution imaging of patterned model biological membranes by localized surface plasmon microscopy", Appl. Opt. 49 (5), 887-891, (2010)
  39. Okazaki, T., Inaba, T., Tatsu, Y., Tero, R., Urisu, T., Morigaki, K. "Polymerized lipid bilayers on solid substrate: Morphologies and obstruction of lateral diffusion", Langmuir 25 (1), 345-351, (2009)
  40. Nomura, K., Inaba, T., Morigaki, K., Brandenburg, K., Seydel, U., Kusumoto, S. "Interaction of lipopolysaccharide and phospholipid in mixed membranes: Solid-state 31P-NMR spectroscopic and microscopic investigations", Biophys. J. 95 1226-1238, (2008)
  41. Ishizuka-Katsura, Y., Wazawa, T., Ban, T., Morigaki, K., Aoyama, S. "Biotin-containing phospholipid vesicle layer formed on the self-assembled monolayer of a saccharide-terminated alkyl disulfide for surface plasmon resonance biosensing", J. Biosci. Bioeng. 105 (5), 527-535, (2008)
  42. Fujiwara, M., Shiokawa, K., Morigaki, K., Tatsu, Y., Nakahara, Y. "Calcium phosphate composite materials including inorganic powders, BSA or duplex DNA prepared by W/O/W interfacial reaction method", Mater. Sci. Eng., C 28 280-288, (2008)
  43. Fujiwara, M., Shiokawa, K., Morigaki, K., Zhu, Y., Nakahara, Y. "Calcium carbonate microcapsules encapsulating biomacromolecules", Chem. Eng. J. (Lausanne) 137 (1), 14-22, (2008)
  44. Yagi, H., Ban, T., Morigaki, K., Naiki, H., Goto, Y. "Visualization and classification of amyloid b supramolecular assemblies ", Biochemistry 46 (51), 15009-15017, (2007)
  45. Morigaki, K., Schönherr, H., Okazaki, T. "Polymerization of diacetylene phospholipid bilayers on solid substrate: Influence of the film deposition temperature ", Langmuir 23 (24), 12254-12260, (2007)
  46. Ueda, Y., Morigaki, K., Tatsu, Y., Yumoto, N., Imaishi, H. "Immobilization and activity assay of cytochrome P450 on patterned lipid membranes", Biochem. Biophys. Res. Commun. 355 926-931, (2007)
  47. Fujiwara, M., Shiokawa, K., Hayashi, K., Morigaki, K., Nakahara, Y. "Direct encapsulation of BSA and DNA into silica microcapsules (hollow spheres)", J. Biomed. Mat. Res. A 81A 103-112, (2007)
  48. Namani, T., Ishikawa, T., Morigaki, K., Walde, P. "Vesicles from docosahexaenoic acid", Colloids Surf. B 54 118-123, (2007)
  49. Okazaki, T., Morigaki, K., Taguchi, T. "Phospholipid vesicle fusion on micropatterned polymeric bilayer substrates", Biophys. J. 91 1757-1766, (2006)
  50. Morigaki, K., Tawa, K. "Vesicle fusion studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy", Biophys. J. 91 1380-1387, (2006)
  51. Ban, T., Morigaki, K., Yagi, H., Kawasaki, T., Kobayashi, A., Yuba, S., Naiki, H., Goto, Y. "Real-time and single fibril observation of the formation of amyloid beta spherulitic structures", J. Biol. Chem. 281 (44), 33677-33683, (2006)
  52. Ikeda, K., Nakazawa, H., Shimo-Oka, A., Ishio, K., Miyata, S., Hosokawa, Y., Matsumura, S., Masuhara, H., Belloncik, S., Alain, R., Goshima, N., Nomura, N., Morigaki, K., Kawai, A., Kuroita, T., Kawakami, B., Endo, Y., Mori, H. "Immobilization of diverse foreign proteins in viral polyhedra and potential application for protein microarrays", Proteomics 6 (1), 54-66, (2006)
  53. Tawa, K., Morigaki, K. "Substrate-supported phospholipid membranes studied by surface plasmon resonance and surface plasmon fluorescence spectroscopy", Biophys. J. 89 2750-2758, (2005)
  54. Morigaki, K., Kiyosue, K., Taguchi, T. "Micropatterned composite membranes of polymerized and fluid lipid bilayers", Langmuir 20 (18), 7729-7735, (2004)
  55. Morigaki, K., Walde, P., Misran, M., Robinson, B. H. "Thermodynamic and kinetic stability. Properties of micelle and vesicle systems formed by decanoic acid/ decanoate", Colloids Surf. A 213 37-44, (2003)
  56. Morigaki, K., Schönherr, H., Frank, C. W., Knoll, W. "Photolithographic polymerization of diacetylene-containing phospholipid bilayers studied by multimode atomic force microscopy", Langmuir 19 (17), 6994-7002, (2003)
  57. Morigaki, K., Walde, P. "Giant vesicles formation from oleic acid/ sodium oleate on glass surfaces induced by adsorbed hydrocarbon molecules", Langmuir 18 (26), 10509-10511, (2002)
  58. Morigaki, K., Baumgart, T., Jonas, U., Offenhäusser, A., Knoll, W. "Photopolymerization of diacetylene lipid bilayers and its application to the construction of micropatterned biomimetic membranes", Langmuir 18 (10), 4082-4089, (2002)
  59. Morigaki, K., Baumgart, T., Offenhäusser, A., Knoll, W. "Patterning solid-supported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid", Angew. Chem., Int. Ed. 40 172-174, (2001)
  60. Fukuda, H., Goto, A., Yoshioka, H., Goto, R., Morigaki, K., Walde, P. "Electron spin resonance study of the pH-induced transformation of micelles to vesicles in an aqueous oleic acid/ oleate system", Langmuir 17 (14), 4223-4231, (2001)
  61. Walde, P., Blochliger, E., Morigaki, K. "Circular dichroic properties of phosphatidylcholine micelles", Langmuir 15 (7), 2346-2350, (1999)
  62. Morigaki, K., Dallavalle, S., Walde, P., Colonna, S., Luisi, P. L. "Autopoietic self-reproduction of chiral fatty acid vesicles", J. Am. Chem. Soc. 119 292-301, (1997)
  63. Morigaki, K., Liu, Z. F., Hashimoto, K., Fujishima, A. "Azobenzene-derivative Langmuir-Blodgett films deposited on various thiol monolayers", J. Phys. Chem. 99 (40), 14771-14777, (1995)
  64. Morigaki, K., Liu, Z. F., Hashimoto, K., Fujishima, A. "In-situ electrochemical actinometry using an azo monolayer film", Ber. Bunsen-Ges. Phys. Chem. 97 860-864, (1993)
  65. Liu, Z. F., Morigaki, K., Enomoto, T., Hashimoto, K., Fujishima, A. "Kinetic studies on thethermal cis-trans isomerization of an azo compound in the assembled monolayer film", J. Phys. Chem. 96 (4), 1875-1880, (1992)
  66. Liu, Z. F., Morigaki, K., Hashimoto, K., Fujishima, A. "Electrochemical actinometry using the assembled monolayer film of an azo compound", Anal. Chem. 64 (2), 134-137, (1992)

Reviews and book chapters (selected)

  1. Morigaki, K., "Patterned model biological membrane composed of polymerizable and natural lipids for reconstituting the membrane functions", Membrane (Maku) 46, 65-70 (2021)
  2. Morigaki, K., "Substrate-supported model membrane as a versatile analytical/ biosensing platform", Anal. Sci. 37, In press (2021)
  3. Yasuhara, K., Morigaki, K., "New lipid membrane technologies for reconstitution, analysis, and utilization of 'living' membrane proteins", Biophys. Physicobiol. 17, 125-129 (2020)
  4. Morigaki, K., Tanimoto, Y. "Evolution and development of model membranes for physicochemical and functional studies of the membrane lateral heterogeneity", Biochim. Biophys. Acta 1860 (10), 2012-2017, (2018)
  5. Morigaki, K. "Micropatterned model biological membranes on a solid surface",  in "Handbook of Biofunctional Surfaces", Knoll, W., Singapore, Pan Stanford Publishing, 639-659, (2012)
  6. Morigaki, K. "Functional interfaces from substrate-supported lipid membranes", Journal of Japanese Society for Biomaterials 27 145-150, (2009)
  7. Morigaki, K. "Micropatterned lipid bilayer membranes on solid substrates",  in "Advances in Planar Lipid Bilayers and Liposomes", Leitmannova-Liu, A., Amsterdam, Elsevier, 9, 107-134, (2009)
  8. Morigaki, K. "Micropatterned model biological membranes composed of polymerized and fluid lipid bilayers", Biointerphases 3 85-89, (2008)
  9. Morigaki, K. and Walde, P. "Fatty acid vesicles", Curr. Opin. Colloid Interface Sci. 12 75-80, (2007)
  10. Walde, P., Namani, T., Morigaki, K. and Hauser, H. "Formation and properties of fatty acid vesicles (liposomes)",  in "Liposome Technology", Gregoriadis, G., New York, Informa Healthcare, 1, 1-19, (2006)
  11. Knoll, W., Morigaki, K., Naumann, R., Sacca, B., Schiller, S. M. and Sinner, E. K. "Functional tethered lipid bilayer membranes",  in "Ultrathin Electrochemical Chemo- and Biosensors - Technology and Performance", Mirsky, V. M., Berlin, Springer, 2, 239-253, (2004)
  12. Morigaki, K., Enomoto, T., Hashimoto, K. and Fujishima, A. "Photoelectrochromic and potentiochromic behaviors of azobenzene LB film", Mol. Cryst. Liq. Cryst. 246 409-412, (1994)
  13. Morigaki, K., Liu, Z. F., Hashimoto, K. and Fujishima, A. "Electrochemical counting of photon number using the assembled monolayer film of azo compound", Sens. Actuators, B 13 226-229, (1993)
  14. Liu, Z. F., Morigaki, K., Hashimoto, K. and Fujishima, A. "New applications of electrochemical techniques", J. Photochem. Photobiol., A 65 285-292, (1992)

Patents

  1. Nanogap-junction-based biochip: JP-6400483, Kenichi Morigaki (September 14, 2018)
  2. Prediction of chemical toxicity with the metabolic patterns of cytochrome P450: JP-5930170, Hiromasa Imaishi, Kenichi Morigaki, Katsuhisa Horimoto (May 13, 2016)
  3. Assay method and kit for measuring the enzymatic activity of diverse cytochrome P450: JP- 5713318, Kenichi Morigaki, Hiromasa Imaishi, Gang Chang, Yoshiro Tatsu (March 20, 2015)
  4. Functional substrate constructed using polymeric lipid bilayer: JP-5532229, Kenichi Morigaki, Takashi Okazaki, Yoshiro Tatsu, Yoshihiro Nakajima (May 9, 2014)
  5. Controlling the lateral diffusion of molecules in a lipid membrane using photo-polymerizable lipid bilayers: JP- 4150793, Kenichi Morigaki (July 11, 2008)

Funding

JSPS Grant in aid (KAKENHI)

  • Reconstitution and functional analysis of photosynthetic machinery in a patterned model membrane: 19H04725, 2019-2020
  • Reconstitution of 2D ordered structures from photo-receptor proteins: 17KT0024, 2017-2019
  • Evaluating the affinity of membrane proteins and lipid raft using a patterned model membrane platform: 17H03666, 2017-2019
  • Model biological membrane having a nanometric gap structure: 15K14489, 2015-2016
  • Evaluating the raftophilicity of membrane proteins in a patterned model membrane: #26291031, 2014-2016
  • Molecular recognition and transport at the nanometric interface between patterned model membrane and micro-structures: #23106714, 2011-2012
  • Concentration and 2D crystallization of proteins in a patterned model membrane: #21651060, 2009-2010
  • Reconstitution of membrane proteins into a patterned model membrane: : #21023021, 2009-2010

Other funding sources

  • Model membrane platforms for light-harvesting: JSPS Joint Research Projects (JPJSBP120195707), 2019-2020
  • Functional roles of 2D ordered photo-receptor clusters in the photo-transduction: Research Foundation for Opto-Science and Technology, 2019-2021
  • Detecting biological molecules using model membrane and nanometric space: Tokyo Ohka Foundation, 2015-2016
  • Evaluating the raftophilicity of G-protein coupled receptors in a patterned model membrane: Hyogo Science and Technology Association, 2014-2015
  • Sensitive detection of biological molecules using a nanogap-junction between model membrane and silicone elastomer: Sumitomo Foundation, 2013-2014
  • Development of a nanometric gap structure between glass substrate and silicone elastomer for the single molecule detection of biological molecules: Nippon Sheet Glass Foundation, 2013-2014

Collaborative funding

  • Localized surface plasmon sensing for subtype determination of influenza viruses in a specimen with ultra-small volume: Dr. Hiroshi Kano (Muroran Institute of Technology), Kakenhi #25286062, 2013-2016
  • Effect of amyloid aggregation on dynamic properties of lipid membranes: Dr. Kenji Sasahara (Kobe University), Kakenhi # 24570185, 2012-2014
  • Localized surface plasmon sensing for detection and diagnosis of influenza viruses: Dr. Hiroshi Kano (Muroran Institute of Technology), Kakenhi # 22360022, 2010-2012
  • Development of a nano-device for evaluating food safety by measuring P450 activities: Dr. Hiromasa Imaishi (Kobe University), Program for Promotion of Basic Research Activities for Innovative Biosciences (PROBRAIN), 2007-2011