論 文・総 説 など
★別刷り請求は宮野までどうぞ 〒657-8501 神戸市灘区六甲台町1-1 神戸大学農学部 miyano@kobe-u.ac.jp
Mammalian Oocyte Growth（卵母細胞の発育）
Cell Cycle in Mammalian Oocytes（卵母細胞の細胞周期）
Fertilization/Early Development of Mammalian Oocytes（卵母細胞の受精・初期発生）
Mammalian Oocyte Growth（卵母細胞の発育）
Miyano T and Hirao Y. In vitro growth of oocytes from domestic species. J. Mamm. Ova Res., 20: in press, 2003.
Senbon S, Hirao Y and Miyano T. Interactions between the oocyte and surrounding somatic cells in follicular development: Lessons from in vitro culture. J. Reprod. Dev., 49: 259-269, 2003.
Senbon S, Ota A, Tachibana M and Miyano T. Bovine oocytes in secondary follicles grow and acquire the meiotic competence in severe combined immuno-deficient mice. Zygote, 11: 139-149, 2003.
宮野 隆. 卵巣内の小さな卵母細胞から成熟卵を作る. サイエンティスト, 2: 2-11, 2003.
Miyano T. Do mammalian primordial oocytes self-initiate their growth? in "Animal Frontier Science", Sato E, Miyamoto H and Manabe N (eds.), Hokuto Shobo, Kyoto, Japan, p. 53-60, 2003.
Miyano T. Bringing up small oocytes to eggs in pigs and cows. Theriogenology, 59: 61-72, 2003.
宮野 隆, 千本正一郎. 卵巣内未成熟卵子の体外受精への応用. Hormone Frontier in Gynecology, 9: 127-134, 2002.
Senbon S and Miyano T. Bovine oocytes in early antral follicles grow in serum-free media: effect of hypoxanthine on follicular morphology and oocyte growth. Zygote,10: 301-309, 2002.
宮野 隆, 千本正一郎. 卵母細胞の体外発育−体外受精. 産婦人科の世界, 54: 585-592, 2002.
Moritake S, Hirao Y, and Miyano T. Hypoxanthine promotes the acquisition of meiotic competence in pig oocytes from early antral follicles during growth culture. J. Mamm. Ova Res., 19: 39-45, 2002.
Miyano T. Bovine small oocytes in culture and xenografts. in "Reproductive Biotechnology", Miyamoto H and Manabe N (eds.), Hokuto Shobo, Kyoto, Japan, p. 221-227, 2001.
宮野隆, 千本正一郎, 太田篤. 未成熟卵子の体外受精への応用. 産科と婦人科, 6: 199-206, 2001.
宮野 隆, 沈 香菊, 平田和正. 卵母細胞による卵胞腔形成の誘導. 日本受精着床学会雑誌, 17: 32-34, 2000.
Miyano T. Cooperation
of oocytes and granulosa cells in mammalian oogenesis. in "Trends:
Graduate School of Science and Technology, Kobe University 1999",
Springer-Verlag, Tokyo, Japan, p. 217-222, 1999.
宮野 隆, 沈 香菊. 体外における卵母細胞の発育と卵胞の発達. 関西畜産学会報, 142: 1-3, 1999.
Ikeda Y, Hirao Y and Miyano T. Effects of androgens on early development of mouse follicles in organ-cultured ovaries. J. Mamm. Ova Res., 16: 148-153, 1999.
宮野 隆, 平尾雄二. 体外発育培養法を用いた卵巣内卵母細胞の利用−その現状と展望−.
日本胚移植学雑誌, 21:16-22, 1999.
Yamamoto K, Otoi T, Koyama N, Horikita N, Tachikawa S and Miyano
T. Development to live young from bovine small oocytes after growth,
maturation and fertilization in vitro. Theriogenology, 52: 81-89,
1999.
宮野 隆. 実験講座「ウシ卵母細胞の体外発育培養法」. 日本胚移植学雑誌, 20: 143-151, 1998.
Miyano T, Moritake S, Hirata K, Miyake M and Kato S. In vitro culture of growing pig oocytes from early antral follicles, J. Mamm. Ova Res., 15: 161-166, 1998.
宮野 隆, 山本 憲, 音井威重. 卵母細胞の体外発育−発育途上卵母細胞からの子ウシ生産の可能性−. 畜産の研究, 52: 1013-1017, 1998.
Osaki S, Matsumura K, Yamamoto K, Miyano T, Miyake M and Kato S. Fertilization of bovine oocytes grown in vitro, Reprod. Fertil. Dev., 9: 781-787, 1998.
Shen X, Miyano T and Kato S. Promotion of follicular antrum formation by pig oocytes in vitro. Zygote 6: 47-54, 1998.
Shen X, Miyano T and Kato S. In vivo and in vitro antrum formation of pig ovarian follicles. in "Reproductive Biology Update: Novel tools for assessment of environmental toxicity", Miyamoto H and Manabe N (eds), Nakanishi Pub. Co., Kyoto, Japan, p. 73-79, 1998.
Miyano T. In vitro growth of small oocytes from porcine and bovine ovaries. in "Reproductive Biology Update: Novel tools for assessment of environmental toxicity", Miyamoto H and Manabe N (eds.), Nakanishi Pub. Co., Kyoto, Japan, p. 105-116, 1998.
Miyano T. Acquisition of meiotic competence during oocyte growth in mammals. J. Mamm. Ova Res., 14: 117-124, 1997.
Shen X, Hirata K, Miyano T and Kato S. In vitro antrum formation of oocyte-cumulus-granulosa cell complexes from pig early antral follicles. J. Mamm. Ova Res., 14: 183-190, 1997.
Harada M, Miyano T, Matsumura K, Osaki S, Miyake M and Kato S. Bovine oocytes from early antral follicles grow to meiotic competence in vitro: effect of FSH and hypoxanthine. Theriogenology, 48: 743-755, 1997.
Prochazka R, Kalab P and Miyano T. EGF stimulated expansion of porcine oocyte-cumulus complexes is affected by the size of the donor follicles. Theriogenology, 47:199, 1997.
宮野 隆. 実験講座「マウス卵母細胞の体外発育培養法」. 日本胚移植学雑誌, 18: 159-166, 1996.
Hirao Y, Tsuji Y,
Miyano T, Okano A, Miyake M, Kato S and Moor RM. Association between
p34cdc2 levels and meiotic arrest in pig oocytes during early
growth. Zygote, 3:325-332, 1995.
Miyano T, Moritake S and Shen X. In vitro growth of mammalian
oocytes. J. Reprod. Dev., 42(Suppl): 71-73, 1996.
宮野 隆. 哺乳類卵母細胞の体外発育.
ETニュースレター, 17: 23-31, 1995.
Miyano T, Hirao Y, Ikeda Y and Kato S. Zona pellicida formation
by naked mouse oocytes grown in vitro, J. Reprod. Dev., 40: 189-195,
1994.
Hirao Y, Nagai T, Kubo M, Miyano T, Miyake M and Kato S. In vitro
growth and maturation of pig oocytes, J. Reprod. Fert., 100: 333-339,
1994.
宮野 隆, 平尾雄二, 加野浩一郎, 永井 卓, 三宅正史, 加藤征史郎. 卵胞卵子の体外発育−体外成熟. 産婦人科の世界,
46:221-228, 1994.
Hirao Y, Miyano T and Kato S. Acquisition of maturational competence in in vitro grown mouse oocytes. J. Exp. Zool., 267: 543-547, 1993.
Hirao Y, Kimura J, Miyano T and Kato S. Effect of PMSG on early oocyte growth and follicular development in newborn mouse ovaries cultured in vitro. J. Reprod. Dev., 39: 13-17, 1993.
Hirao Y, Miyano T and Kato S. Fertilization of in vitro grown mouse oocytes. Theriogenology, 34: 1071-1077, 1990.
Miyano T, Akamatsu J, Kato S, Nanjo I and Kanda S. Ovarian development in Meishan pigs. Theriogenology, 33: 769-775, 1990.
宮野 隆, 平尾雄二, 加藤征史郎, 苅田 淳. 器官培養マウス卵巣における卵母細胞の発達. 日本畜産学会報, 59: 848-853, 1988.
宮野 隆, 平尾雄二, 加藤征史郎, 苅田 淳. マウス卵巣における卵母細胞の発達と透明帯の形成. 家畜繁殖学雑誌, 34, 61-66, 1988.
Cell Cycle in Mammalian Oocytes（卵母細胞の細胞周期）
Miyano T, Lee J and Fulka J Jr. G2/M transition of pig oocytes: How oocytes initiate maturation? Reprod. Med. Biol., 2: 91-99, 2003.
Villa-Diaz LG and Miyano T. The extracellular regulated kinase, MAPK in porcine oocytes during maturation. in "Animal Frontier Science", Sato E, Miyamoto H and Manabe N (eds.), Hokuto Shobo, Kyoto, Japan, p. 75-79, 2003.
Kanayama N, Lee J and Miyano T. Acquisition of meiotic competence in growing pig oocytes correlates with their ability to activate Cdc2 kinase and MAP kinase. Zygote, 10, 261-270, 2002.
Miyano T. and Lee J. Change in cyclin B1 and MAP kinase molecules during maturation and fertilization of pig oocytes. in "Reproductive Biotechnology", Miyamoto H and Manabe N (eds.), Hokuto Shobo, Kyoto, Japan, p. 9-19, 2001.
Miyano T, Dai Y, Lee J, Kano K and Moor RM. Degradation of pig cyclin B1 molecules precedes MAP kinase dephosphorylation during fertilization of the oocytes. Zygote, 8: 153-158, 2000.
Lee J, Miyano T and Moor RM. Localization of phosphorylated MAP kinase during the transition from meiosis I to meiosis II in pig oocytes. Zygote, 8: 119-125, 2000.
Lee J, Miyano T and Moor RM. Spindle formation and dynamics of gamma-tubulin and NuMA distribution during meiosis in pig and mouse oocytes. Biol. Reprod., 62: 1184-1192, 2000.
Prochazka R, Srsen V, Nagyova E, Miyano T and Flechon JE. The developmental regulation of effect of epidermal growth factor on porcine oocyte-cumulus cell-complexes: nuclear maturation, expansion and F-actin remodeling, Mol. Reprod. Dev., 56: 63-73, 2000.
Tsuji-Goto Y and Miyano T. Meiotic resumption of pig oocytes by cAMP-dependent protein kinase inhibitor H89. Mamm. Ova Res., 17: 58-63, 2000
Lee J, Miyano T, Dai Y, Wooding P, Yen TJ and Moor RM. Specific regulation of CENP-E and kinetochores during meiosis I/meiosis II transition in pig oocytes. Mol. Reprod. Dev., 56: 51-62, 2000.
Miyano T. Cooperation
of oocytes and granulosa cells in mammalian oogenesis. in "Trends:
Graduate School of Science and Technology, Kobe University 1999",
Springer-Verlag, Tokyo, Japan, p. 217-222, 1999.
Lee J, Hata K, Miyano T, Yamashita M, Dai Y and Moor RM. Tyrosine
phosphorylation of p34cdc2 in metaphase II-arrested pig oocytes
results in pronucleus formation without chromosome segregation,
Mol. Reprod. Dev., 52: 107-116, 1999.
Miyano T. Acquisition of meiotic competence during oocyte growth in mammals. J. Mamm. Ova Res., 14: 117-124, 1997.
Miyano T, Moor RM, Wooding FBP and Shiroo M. Localization and function of tyrosine-phosphorylated protein in pig oocytes. Mol. Reprod. Dev., 44: 408-416, 1996.
Miyano T, Lee J
and Goto Y. Meiotic resumption of growing pig oocytes by H89 and
okadaic acid, in"Proceedings of 7th French-Czech-Slovak Conference
about PHYSIOLOGY OF REPRODUCTION", p.13, 1996.
Miyano T, Ebihara M, Goto Y, Hirao Y, Nagai T and Kato S. Inhibitory
action of hypoxanthine on meiotic resumption of denuded pig follicular
oocytes in vitro. J. Exp. Zool., 273: 70-75, 1995.
Hirao Y, Tsuji Y, Miyano T, Okano A, Miyake M, Kato S and Moor
RM. Association between p34cdc2 levels and meiotic arrest in pig
oocytes during early growth. Zygote, 3: 325-332, 1995.
Moor RM, Jung T, Miyano T and Baker P. Cyclin and p34cdc2 kinase activity in pig oocytes during the G2- to M-phase transition. "Gonadal Development and Function", Hillier SG (ed.), Raven Press, New York, p. 85-98, 1992.
Fertilization/Early Development of Mammalian Oocytes（卵母細胞の受精・初期発生）
Kren R, Kikuchi K, Myiano T, Ogushi S, Nagai T, Fulka J and Fulka J Jr. Intracytoplasmic sperm injection in the pig: Where is the problem? J. Reprod. Dev., 49: 271-273, 2003.
Okada K, Miyano T. and Miyake M. Artificial activation of mouse and pig mature oocytes by divalent cations, in "Animal Frontier Science", Sato E, Miyamoto H and Manabe N (eds.), Hokuto Shobo, Kyoto, Japan, p. 213-217, 2003.
Okada K, Miyano T and Miyake M. Activation of pig oocytes by intracytoplasmic injection of strontium and barium. Zygote, 11: 159-165, 2003.
Katayama M, Miyano T, Miyake M and Kato S. Progesterone treatment of boar spermatozoa improves male pronuclear formation after intracytoplasmic sperm injection into porcine oocytes. Zygote, 10: 95-104, 2002.
Kano K, Miyano T and Kato S. Effects of glycosaminoglycans on the development of in vitro-matured and -fertilized porcine oocytes to the blastocyst stage in vitro. Biol. Reprod., 58: 1226-1232, 1998.
Kano K, Miyano T
and Kato S. Effect of oviductal epitherial cells on fertilization
of pig oocytes in vitro. Theriogenology, 42: 1061-1068, 1994.
Kano K, Miyano T and Kato S. Ovarian response to exogenous gonadotropins
and in vitro fertilization of follicular oocytes in prepubertal
Chinese Jinhua pigs. J. Reprod. Dev., 40: 91-97, 1994.
Miyano T, Hiro-oka RE, Kano K, Miyake M, Kusunoki H and Kato S.
Effect of hyaluronic acid on the development of 1- and 2-cell
porcine embryos to the blastocyst stages in vitro. Theriogenology,
41: 1299-1305, 1994.
Kano K, Miyano T, Miyake M and Kato S. Effect of caffeine and
sperm preincubation on penetration of pig oocytes by ejaculated
spermatozoa, Anim. Sci. Tech., 65: 271-276, 1994.
Kano K, Hiro-oka R, Miyano T and Kato S. Effects of the time of maturation culture and subsequent co-culture with spermatozoa on fertilization and early cleavage of pig oocytes in vitro. J. Mamm. Ova Res., 10: 175-184, 1993.
加野浩一郎, 宮野 隆, 加藤征史郎.
ブタ卵胞卵子の体外成熟および体外受精に及ぼすヒト閉経期性腺刺激ホルモン(hMG)の影響.
繁殖技術研究会誌, 15: 29-34, 1993.
Hirao Y, Miyano T and Kato S. Fertilization of in vitro grown mouse oocytes. Theriogenology, 34: 1071-1077, 1990.
Miyano T, Yoshikawa K, Kato S, Harayama H, Nanjo I and Kanda S. In vitro fertilization of in vitro and in vivo matured oocytes from prepubertal Meishan gilts. Jpn. J. Zootech. Sci., 61: 1011-1016, 1990.