Members

Education and Experience

Mar. 2008

B.S., Faculty of Human Development, Kobe University

Mar. 2010

M.S., Graduate School of Biostudies, Kyoto University

Apr. 2010

Research associate, Matsutani Chemical Industry Co.,Ltd.

Apr. 2014-Dec. 2022

Senior research associate, Matsutani Chemical Industry Co.,Ltd.

Mar. 2020

Ph.D. (Life Sciences), The United Graduate School of Agricultural Science, Ehime University

Oct. 2018-Dec. 2022

Collaborative researcher, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Jan. 2023-Mar. 2023

Assistant Professor in Engineering Biology Research Center, Kobe University

Apr. 2023-present

Assistant Professor in Graduate School of Science, Technology and Innovation, Kobe University

Publications

1. Shintani, T.*, Yanai, S., Kanasaki, A., Tanaka, M., Iida, T., Ozawa, G., Kunihiro, T., Endo, S. (2022/11) Long-term D-Allose Administration Favorably Alters the Intestinal Environment in Aged Male Mice, Journal of Applied Glycoscience, 69(4), 97-102
2. Shintani, H., Ashida, H., Shintani, T.* (2021/12) Shifting the focus of d-glucosamine from a dietary supplement for knee osteoarthritis to a potential anti-aging drug, Human nutrition and metabolism, 26, 200134
3. Mizuta, N., Kosho, H., Nagata, Y., Shintani, T., Tanaka, K. (2021/03) Co-administration of D-Allulose and Soy Protein Favorably and Additively Alters Lipid Metabolism in Sprague-Dawley Rats, ACS Food Science & Technology, 1(3), 418-426
4. Shintani, H., Shintani, T.* (2020/12) Effects of antidiabetic drugs that cause glucose excretion directly from the body on mortality, Medicine in Drug Discovery, 8, 100062
5. Shintani, T.* (2020/12) Human antiaging research: A viewpoint from food science on calorie restriction mimetics, Food Research, 4(6), 2333-2335
6. Shintani, H., Sintani, T.*, Sato, M. (2020/08) D-allose of a trace component in human serum and its medical applicability, International Journal of Applied Biology and Pharmaceutical Technology, 11, 170-183
7. Sintani, T.* (2020/07) Processing and use of starch in food in Japan, Journal of Food Science and Nutrition Research, 3，140-152
8. Sakoguchi, H., Shintani, T., Ishiyama, H., Yanagita, R.C., Kawanami, Y., Sato, M. (2019/12) Nematocidal activity of 6-O-octanoyl- and 6-O-octyl-D-allose against larvae of Caenorhabditis elegans, Bioscience Biotechnology Biochemistry, 83(12), 2194-2197
9. Shintani, T.*, Sakoguchi, H., Yoshihara, A., Izumori, K., Sato, M. (2019/11) D-Allose, a stereoisomer of D-glucose, extends the lifespan of Caenorhabditis elegans via sirtuin and insulin signaling, Journal of Applied Glycoscience, 66(4), 139-142
10. Yoshihara, A., Sakoguchi, H., Shintani, T., Fleet, G.W.J., Izumori, K., Sato, M. (2019/09) Growth inhibition by 1-deoxy-D-allulose, a novel bioactive deoxy sugar, screened using Caenorhabditis elegans assay, Bioorganic & Medicinal Chemistry Letters, 29(17), 2483-2486
11. Shintani, T.* (2019/06) Food Industrial Production of Monosaccharides Using Microbial, Enzymatic, and Chemical Method, Fermentation, 5(2), 47
12. Shintani, H., Shintani, T.*, Ashida, H., Sato, M. (2018/11) Calorie Restriction Mimetics: Upstream-Type Compounds for Modulating Glucose Metabolism, Nutrients, 10(12), E1821
13. Shintani, T., Kosuge, Y., Ashida, H. (2018/08) Glucosamine Extends the Lifespan of Caenorhabditis elegans via Autophagy Induction, Journal of Applied Glycoscience, 65(3), 37-43
14. Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., Sato, M. (2017/12) D-Allulose, a stereoisomer of D-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic, Biochemical and Biophysical Research Communications, 493(4), 1528-1533
15. Yamada, T., Shintani, T., Iida, T., Kishimoto, Y., Okuma, K. (2017/12) Effect of Ingestion of Rare Sugar Syrup on the Blood Glucose Response in Humans, Journal of Japanese Society of Nutrition and Food Science, 70(6), 271-278
16. Nakamura, M., Yamada, T., Shintani, T., Yumiba, K., Kishimoto, Y., Iida, T. (2017/04) Effect of Rare Sugar Syrup on α-Glucosidase Inhibition and on Blood Glucose Response with Sucrose in Humans, Japanese Pharmacology and Therapeutics, 45(4), 587-594
17. Shintani, T.*, Yamada, T., Hayashi, N., Iida, T., Nagata, Y., Ozaki, N., Toyoda, Y. (2017/02) Rare Sugar Syrup Containing D-Allulose, but not High Fructose Corn Syrup, Maintains Glucose Tolerance and Insulin Sensitivity Partly via Hepatic Glucokinase Translocation in Wistar Rats, Journal of Agricultural and Food Chemistry, 65(13), 2888-2894
18. Yoshihara, A., Kozakai, T., Shintani, T., Matsutani, R., Ohtani, K., Iida, T., Akimitsu, K., Izumori, K., Gullapalli, PK. (2017/02) Purification and characterization of d-allulose 3-epimerase derived from Arthrobacter globiformis M30, a GRAS microorganism, Journal of Bioscience and Bioengineering, 123(2), 170-176
19. Sakoguchi, H., Yoshihara, A., Shintani, T., Okuma, K., Izumori, K., Sato, M. (2016/02) Growth inhibitory effect of D-arabinose against the nematode Caenorhabditis elegans: Discovery of a novel bioactive monosaccharide, Bioorganic & Medicinal Chemistry Letters, 26(3), 726-729
20. Shintani, T., Yamazaki, F., Katoh, T., Umekawa, M., Matahira, Y., Hori, S., Kakizuka, A., Totani, K., Yamamoto, K., Ashida, H. (2010/01) Glucosamine induces autophagy via an mTOR-independent pathway, Biochemical and Biophysical Research Communications, 391(4), 1775-1779

Reviews & Commentaries

1. 土橋竜也, 新谷知也, 希少糖プシコースの機能性と応用, 食品と開発, 9月号, 14-16 (2020)
2. 新谷知也, 新谷英也, 佐藤正資, 芦田久, 老化遅延効果が期待されるヘキソースと健康長寿戦略, 応用糖質科学, 9巻，2号, 98-102 (2019/05)
3. 秋光和也, 村尾孝児, 小川雅廣, 新谷知也, 何森健，希少糖研究の眺望-3 さまざまな分野における希少糖作用の応用, 希少糖資源による新規用途開発への挑戦, 化学と生物, 57巻，1号，50-57 (2018/12)
4. 新谷知也, 芦田久, 佐藤正資, カロリー制限模倣効果を発揮するヘキソース, 化学と生物, 56巻, 12号, 777-778 (2018/12)
5. 新谷知也, 飯田哲郎, 希少糖の開発と利用, 明日の食品産業, 2015巻, 4号, 34-41 (2015/04)
6. 新谷知也, 飯田哲郎, 脱かくれ肥満　カロリー制限模倣甘味料としての希少糖, FoodStyle21, 17巻, 9号, 64-66 (2013/09)
7. 新谷知也, 大隈一裕, 砂古口博文, 佐藤正資, カロリー制限模倣物質としての希少糖D-プシコース及びD-アロース―抗メタボリックシンドローム効果からアンチエイジング効果へ―, 日本醸造協会誌, 108巻, 8号, 565-574 (2013)

Books

1. 新谷知也, 佐藤正資. D-アルロース、D-アロースおよびD-グルコサミンの寿命延長効果, 生物の寿命延長 ～老化・長寿命の基盤研究最前線～, エヌ・ティー・エス, 255-233, (2022/03)
2. Shintani, T., Upadhyay, SK., Singh, SP. An introduction to microbial biodiversity and bio-prospection, Bioprospecting of Plant Biodiversity for Industrial Molecules, Wiley (2021/12)
3. Shintani, T., Lema-Perez, L., Shintani, H. The sugars with the potential to prolong human life, Sugar Intake - Risks and Benefits, IntechOpen (2021/08)