Members

Education and Experience

Apr, 2012 – Mar, 2016

Division of Applied Science, School of Engineering, The University of Osaka

Apr, 2016 – Mar, 2021

Department of Applied Chemistry, Graduate School of Engineering, The University of Osaka

Sep, 2017 – Dec, 2017

RWTH Aachen University, Institute of Biotechnology, Visiting Researcher

Apr, 2018 – Mar, 2021

Japan Society for the Promotion of Science Researcher DC1

Aug, 2018 – Dec, 2018

RWTH Aachen University, Institute of Biotechnology, Visiting Researcher

Apr, 2021 – Jun, 2025

Assistant Professor, Department of Applied Chemistry, Graduate School of Engineering, The University of Osaka

　

Jul, 2025 – Present

Associate Professor, Engineering Biology Research Center, Kobe University

Awards

• Sep 2024, Lecture Award, 18th Symposium on Biorelevant Chemistry, Division of Biofunctional Chemistry, The Chemical Society of Japan
• Jul 2021, Lecture Award, SRM 2021
• Oct 2019, Lecture Award, SRM 2021, The 69th Conference of Japan Society of Coordination Chemistry
• Jun 2019, 15th International Symposium on Applied Bioinorganic Chemistry (ISABC15) Poster Award
• Mar 2016, 大阪大学 工学賞

Publications

1. Kato, S., Nishiwaki, H., Endo, E., Hayashi, T. (2025/08) Radical Ring‐Opening Reaction of Non‐Activated Oximes Catalyzed by Aldoxime Dehydratases, Angewandte Chemie International Edition, in press, e202511590
2. Kato, S., Abe, M., Okahashi, N., Ariyasu, S., Matsuda, F., Shoji, O., Hayashi, T. (2025/08) Metabolic Engineering of the 5-Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein-Based Biocatalysis, Angewandte Chemie International Edition, in press, e202505875
3. Kato, S., Fujisawa, S., Adachi, Y., Bandai, M., Mori, Y., Mori, S., Shirai, T., Hayashi, T. (2025/04) NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent Enzymes, Journal of the American Chemical Society, 147(17), 14837–14844
4. Kato, S., Abe, M., Gröger, H., Hayashi, T. (2024/08) Reconstitution of Myoglobin with Iron Porphycene Generates an Artificial Aldoxime Dehydratase with Expanded Catalytic Activities, ACS Catalysis, 14(17), 13081–13087
5. Kato, S., Takeuchi, K., Iwaki, M., Miyazaki, K., Honda, K., Hayashi, T. (2023/06) Chitin‐ and Streptavidin‐Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery, Angewandte Chemie International Edition, 62(31), e202304721
6. Kato, S., Onoda, A., Schwaneberg, U., Hayashi, T. (2023/03) Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold, Journal of the American Chemical Society, 145(15), 8285–8290
7. Kato, S., Onoda, A., Grimm, A. R., Schwaneberg, U., Hayashi, T. (2021/03) Construction of a Whole-Cell Biohybrid Catalyst Using a Cp*Rh(III)-Dithiophosphate Complex as a Precursor of a Metal Cofactor, Journal of Inorganic Biochemistry, 216, 111352
8. Kato, S., Onoda, A., Taniguchi, N., Schwaneberg, U., Hayashi, T. (2021/02) Directed Evolution of a Cp*Rh(III)-Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification, ChemBioChem, 22(4), 679–685
9. Kato, S., Onoda, A., Grimm, A. R., Tachikawa, K., Schwaneberg, U., Hayashi, T. (2020/10) Incorporation of a Cp*Rh(III)-Dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)–H Bond Functionalization, Inorganic Chemistry, 59(19), 14457–14463
10. Miyazawa, T., Suzuki, T., Kumagai, Y., Takizawa, K., Kikuchi, T., Kato, S., Onoda, A., Hayashi, T., Kamei, Y., Kamiyama, F., Anada, M., Kojima, M., Yoshino, T., Matsunaga, S. (2020/10) Chiral Paddle-Wheel Diruthenium Complexes for Asymmetric Catalysis, Nature Catalysis, 3(10), 851–858
11. Grimm, A. R., Sauer, D. F., Davari, M. D., Zhu, L., Bocola, M., Kato, S., Onoda, A., Hayashi, T., Okuda, J., Schwaneberg, U. (2018/04) Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis, ACS Catalysis, 8(4), 3358–3364
12. Himiyama, T., Taniguchi, N., Kato, S., Onoda, A., Hayashi, T. (2017/10) A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction, Angewandte Chemie International Edition, 56(44), 13618–13622

Reviews & Commentaries

1. 加藤俊介，若手研究者からのメッセージ，日本化学会バイオテクノロジー部会ニュースレター28: 9-13, (2025)
2. 加藤俊介, 二置換シクロプロパンのstereodivergent合成を目的とした微生物ヘム依存性酵素の探索，日本化学会生体機能関連化学部会ニュースレター39: 5-9, (2024)
3. 加藤俊介, 林高史, キチン粉末を利用したタンパク質精製手法の開発と酵素探索への応用，酵素工学ニュース92: 23-25, (2024)
4. 加藤俊介, 海外研究室レポート アーヘン工科大学での研究生活，Organo Metallics NEWS143: 36-37, (2023)
5. 加藤俊介, 酵素で光り輝く有機合成，化学78: 59-60, (2023)
6. 加藤俊介, 林高史, 代表的な鉄含有タンパク質の構造と生体機能，金属91: 21-29, (2021)
7. 加藤俊介, 林高史, 人工金属酵素の創製－非天然の金属錯体を生体分子へ－，化学と教育66: 588-591, (2018)

Books

1. Hayashi, T., Kato, S., Engineering of hemoproteins. Comprehensive Inorganic Chemistry III. Reedijk, J. and Poeppelmeier, KR. eds. Elsevier, 2.09, 215-230, (ISBN: 9780128231449) (分担執筆) (2023)
2. 加藤俊介, 林高史, 水中で触媒する人工金属酵素, 水中有機合成の開発動向, 小林修, 北之園拓　監修, シーエムシー出版, 23, 215-230, (ISBN：9784781316635) (分担執筆) (2022)