Members

BioProduction Engineering Lab Members (Eng. Biol. Res. C) Shunsuke Kato

Associate ProfessorShunsuke Kato

Education and Experience

Apr, 2012 – Mar, 2016
Division of Applied Science, School of Engineering, The University of Osaka
Apr, 2016 – Mar, 2021
Department of Applied Chemistry, Graduate School of Engineering, The University of Osaka
Sep, 2017 – Dec, 2017
RWTH Aachen University, Institute of Biotechnology, Visiting Researcher
Apr, 2018 – Mar, 2021
Japan Society for the Promotion of Science Researcher DC1
Aug, 2018 – Dec, 2018
RWTH Aachen University, Institute of Biotechnology, Visiting Researcher
Apr, 2021 – Jun, 2025
Assistant Professor, Department of Applied Chemistry, Graduate School of Engineering, The University of Osaka
　
Jul, 2025 – Present
Associate Professor, Engineering Biology Research Center, Kobe University
　
Nov, 2025 – Present
Associate Professor, Graduate School of Science, Technology and Innovation, Kobe University

Awards

  • Feb 2026, Young Investigator Award, 27th Enzyme Application Symposium
  • Sep 2024, Lecture Award, 18th Symposium on Biorelevant Chemistry, Division of Biofunctional Chemistry, The Chemical Society of Japan
  • Jul 2021, Lecture Award, SRM 2021
  • Oct 2019, Lecture Award, SRM 2021, The 69th Conference of Japan Society of Coordination Chemistry
  • Jun 2019, 15th International Symposium on Applied Bioinorganic Chemistry (ISABC15) Poster Award
  • Mar 2016, Engineering Award, Osaka University

Publications

  1. Kato, S.,* Hasunuma, T.* (2026/04) Expanding the Chemical Space of Biosynthesis through Chemistry-Inspired Enzymatic Transformations, Current Opinion in Biotechnology, in press
  2. Sekiya, R., Nakamoto, M.,* Kato, S., Hayashi, T., Matsusaki, M.* (2026/03) Injectable and transient hydrogel with programmable lifetime by endogenous coordination crosslinking and enzymatic de-crosslinking, Journal of Controlled Release, 394, 114867
  3. Takeuchi, K., Kato, S.,* Ueshima, R., Hayashi, T.* (2026/01) Directed Evolution Enhances the Peroxidation Activity of Myoglobin Reconstituted with an Iron Corrole Complex, Bulletin of the Chemical Society of Japan, 99(2), uoag024
  4. Kato, S.,* Takeuchi, K., Umeda, K., Kudo, H., Hasunuma, T., Hayashi, T.* (2026/01) PCA-Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation, Angewandte Chemie International Edition, 65(10), e26025
  5. Abe, M., Takeuchi, M., Kato, S.,* Hasunuma, T., Groger, H., Hayashi, T.* (2026/01) Organic solvent-tolerant bacteria as a host for whole-cell biocatalysis: Enzymatic dehydration of aldoximes in organic medium, Journal of Porphyrins and Phthalocyanines, 29, A-F
  6. Becker, T., Takeuchi, K., Süßmuth, C., Boekhoff, F., Schäfer, M. A., Kato, S., Hoffmann, A., Hayashi, T., Herres-Pawlis, S.* (2025/10) All-Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters, Advanced Science, 13(8), e11260
  7. Kato, S.,* Nishiwaki, H., Endo, E., Hayashi, T.* (2025/08) Radical Ring‐Opening Reaction of Non‐Activated Oximes Catalyzed by Aldoxime Dehydratases, Angewandte Chemie International Edition, 64(45), e202511590
  8. Kato, S.,* Abe, M., Okahashi, N., Ariyasu, S., Matsuda, F., Shoji, O., Hayashi, T.* (2025/08) Metabolic Engineering of the 5-Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein-Based Biocatalysis, Angewandte Chemie International Edition, 64(39), e202505875
  9. Kato, S.,* Fujisawa, S., Adachi, Y., Bandai, M., Mori, Y., Mori, S., Shirai, T., Hayashi, T.* (2025/04) NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent Enzymes, Journal of the American Chemical Society, 147(17), 14837–14844
  10. Kato, S.,* Abe, M., Gröger, H., Hayashi, T.* (2024/08) Reconstitution of Myoglobin with Iron Porphycene Generates an Artificial Aldoxime Dehydratase with Expanded Catalytic Activities, ACS Catalysis, 14(17), 13081–13087
  11. Kato, S.,* Takeuchi, K., Iwaki, M., Miyazaki, K., Honda, K., Hayashi, T.* (2023/06) Chitin‐ and Streptavidin‐Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery, Angewandte Chemie International Edition, 62(31), e202304721
  12. Kato, S., Onoda, A.,* Schwaneberg, U., Hayashi, T.* (2023/03) Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold, Journal of the American Chemical Society, 145(15), 8285–8290
  13. Kato, S., Onoda, A.,* Grimm, A. R., Schwaneberg, U., Hayashi, T.* (2021/03) Construction of a Whole-Cell Biohybrid Catalyst Using a Cp*Rh(III)-Dithiophosphate Complex as a Precursor of a Metal Cofactor, Journal of Inorganic Biochemistry, 216, 111352
  14. Kato, S., Onoda, A.,* Taniguchi, N., Schwaneberg, U., Hayashi, T.* (2021/02) Directed Evolution of a Cp*Rh(III)-Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification, ChemBioChem, 22(4), 679–685
  15. Kato, S., Onoda, A.,* Grimm, A. R., Tachikawa, K., Schwaneberg, U., Hayashi, T.* (2020/10) Incorporation of a Cp*Rh(III)-Dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)–H Bond Functionalization, Inorganic Chemistry, 59(19), 14457–14463
  16. Miyazawa, T., Suzuki, T., Kumagai, Y., Takizawa, K., Kikuchi, T., Kato, S., Onoda, A., Hayashi, T., Kamei, Y., Kamiyama, F., Anada, M., Kojima, M., Yoshino, T.,* Matsunaga, S.* (2020/10) Chiral Paddle-Wheel Diruthenium Complexes for Asymmetric Catalysis, Nature Catalysis, 3(10), 851–858
  17. Grimm, A. R., Sauer, D. F., Davari, M. D., Zhu, L., Bocola, M., Kato, S., Onoda, A., Hayashi, T., Okuda, J.,* Schwaneberg, U.* (2018/04) Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis, ACS Catalysis, 8(4), 3358–3364
  18. Himiyama, T., Taniguchi, N., Kato, S., Onoda, A.,* Hayashi, T.* (2017/10) A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction, Angewandte Chemie International Edition, 56(44), 13618–13622

Reviews & Commentaries

  1. 加藤俊介, 有機化学から代謝反応を考える，生物工学会誌 バイオミディア104(2): 68, (2026)
  2. 加藤俊介, 若手研究者からのメッセージ，日本化学会バイオテクノロジー部会ニュースレター28: 9-13, (2025)
  3. 加藤俊介, 二置換シクロプロパンのstereodivergent合成を目的とした微生物ヘム依存性酵素の探索，日本化学会生体機能関連化学部会ニュースレター39: 5-9, (2024)
  4. 加藤俊介, 林高史, キチン粉末を利用したタンパク質精製手法の開発と酵素探索への応用，酵素工学ニュース92: 23-25, (2024)
  5. 加藤俊介, 林高史, キチン／キチン結合タンパク質を利用した簡便なタンパク質精製手法，バイオサイエンスとインダストリー82: 158-159, (2024)
  6. 加藤俊介, 海外研究室レポート アーヘン工科大学での研究生活，Organo Metallics NEWS143: 36-37, (2023)
  7. 加藤俊介, 酵素で光り輝く有機合成，化学78: 59-60, (2023)
  8. 加藤俊介, 林高史, 代表的な鉄含有タンパク質の構造と生体機能，金属91: 21-29, (2021)
  9. 加藤俊介, 林高史, 人工金属酵素の創製－非天然の金属錯体を生体分子へ－，化学と教育66: 588-591, (2018)

Books

  1. Hayashi, T., Kato, S., Engineering of hemoproteins. Comprehensive Inorganic Chemistry III. Reedijk, J. and Poeppelmeier, KR. eds. Elsevier, 2.09, 215-230, (ISBN: 9780128231449) (分担執筆) (2023)
  2. 加藤俊介, 林高史, 水中で触媒する人工金属酵素, 水中有機合成の開発動向, 小林修, 北之園拓　監修, シーエムシー出版, 23, 215-230, (ISBN：9784781316635) (分担執筆) (2022)